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Visualizing Alzheimer's disease
Using recently developed techniques for imaging individual cells in living animals, a team led by researchers at Washington University School of Medicine in St. Louis has watched as Alzheimer's-like brain plaques damage mouse brain cells. (2003-11-12)

Strange creatures accidentally discovered beneath Antarctica's ice shelves
Prior research has suggested that the watery depths below the Antarctic ice shelves are too cold and nutrient poor to sustain much life. But a new study from British Antarctic Survey published in Frontiers in Marine Science reveals the discovery of a colony of sponges and other animals attached to a boulder on the sea floor - challenging researchers' understanding about the existence of life in extreme environments. (2021-02-15)

Protein conjugation method offers new possibilities for biomaterials
Northwestern University Professor Michael Jewett and his research team have demonstrated a novel method in which protein-polymer conjugates can display new and unique types of functionalities. (2015-09-24)

Shedding light on luminescence: Scientists visualize structure of the photoprotein aequorin
In this week's issue of the journal Nature, Shimomura and his colleagues James Head from Boston University, Katsunori Teranishi from Mei University (Japan), and Satoshi Inouye from Chisso Corporation (Japan), describe the three- dimensional crystal structure of aequorin, the photoprotein that illuminates jellyfish, centophores and many other luminescing organisms. The study was supported by the National Science Foundation. (2000-05-17)

Expression of infrared fluorescence engineered in mammals
Researchers at the University of California, San Diego -- led by 2008 Nobel-Prize winner Roger Tsien, Ph.D. -- have shown that bacterial proteins called phytochromes can be engineered into infrared-fluorescent proteins. Because the wavelength of IFPs is able to penetrate tissue, these proteins are suitable for whole-body imaging in small animals. Their findings will be published in the May 8 edition of the journal Science. (2009-05-07)

Capturing the balance of nature
Researchers capture dynamic changes in marine life over twelve years. (2018-03-02)

Lighting up life: Cold Spring Harbor Protocols presents tips for creating glowing plants
The current issue of Cold Spring Harbor Protocols provides advice on choosing appropriate plant tissues, designing test proteins for maximal GFP detection and setting up microscope equipment for imaging in plants. This information will be useful to a broad range of scientists interested in plant biology and imaging technologies. (2007-02-01)

The consequences of exploiting the ocean depths
A group of international experts has just published an article in the prestigious review Nature in which they suggest responses to question such as how organisms live in the Twilight zone and how diverse they are; which organic processes transform and consume the zone's organic material; and how the organic material is carried into and out of it (2020-06-01)

Columbia crew catches a mysterious TIGER in the Indian Ocean
An unprecedented flash observed by the space shuttle Columbia crew in 2003 over the Indian Ocean may be a new type of transient luminous event, like lightning sprites, but one that is not necessarily caused by a thunderstorm. The authors describe the discharge as a Transient Ionospheric Glow Emission in Red, or TIGER, event. The authors analyzed the video and found what visually looks like a bright flash. They report that the emission did not resemble any known class of luminous events. (2005-01-17)

Monster mystery solved
Tully monsters, bizarre aquatic animals that lived in what's now Illinois 307 million years ago, have defied categorization for decades -- until now. New research has shown that they're vertebrates: specifically, jawless fish. (2016-03-16)

Mature stem cell transplants linked to treatment of cerebral palsy
Whether transplantation of mature stem cells can help babies with cerebral palsy is the study focus of a Medical College of Georgia physician-scientist. Dr. James E. Carroll, chief of the Section of Pediatric Neurology, has received a two-year grant from the National Institutes of Health to pursue whether brain damage that occurs during the birth of these babies can be repaired with transplants. (2002-05-29)

Monterey Bay Aquarium study finds sea turtles use flippers to manipulate food
Sea turtles use their flippers to handle prey despite the limbs being evolutionarily designed for locomotion, a discovery by Monterey Bay Aquarium researchers published in PeerJ. Research by Jessica Fujii and Dr. Kyle Van Houtan and others reveals a behavior thought to be less likely in marine tetrapods is actually widespread and that this type of exaptation of flippers may have been occurring 70 million years earlier than previously thought. (2018-03-28)

Computing toxic chemicals
A new computational method for working out in advance whether a chemical will be toxic will be reporting in a forthcoming issue of the International Journal of Data Mining and Bioinformatics. (2013-07-18)

Mathematical modeling predicts cellular communication
In a tour de force combination of mathematical modeling and precise quantitative measurements, Marc Kirschner, of Harvard Medical School, Reinhart Heinrich, of Humboldt University, Berlin, and colleagues push the envelope of our understanding of the Wnt signaling pathway, which plays a role both in various stages of embryonic development and in carcinogenesis. (2003-10-13)

Revealing bizarre deep-sea secrets
On Saturday, Aug. 7, Harbor Branch marine biologists and others will set out from Panama City, Fla. on an expedition called Operation Deep Scope to study the fantastic life forms of four alien landscapes in the deep reaches of the Gulf of Mexico. The team will be using the most advanced array of imaging tools ever deployed in the deep sea with the goal of revealing never before seen animals, behaviors, and phenomena. (2004-08-06)

Seeing without eyes: Hydra stinging cells respond to light
In the absence of eyes, the fresh water polyp, Hydra magnipapillata, nevertheless reacts to light. New research published in BioMed Central's open-access journal BMC Biology shows that stinging cells in hydra tentacles, which the animals use for self protection and to catch prey, are linked via a simple nervous system to primitive light responsive cells that coordinate the animals' feeding behavior. (2012-03-04)

A question of time
Researchers show how the immune system distinguishes between self molecules and non-self molecules such as those from pathogens. (2019-05-03)

Potential new painkiller provides longer lasting effects
Medications have long been used to treat pain caused by injury or chronic conditions. Unfortunately, most are short-term fixes or cause side effects that limit their use. Researchers at the University of Missouri have discovered a new compound that offers longer lasting painkilling effects, and shows promise as an alternative to current anesthetics. (2015-05-07)

Renegade genes caught red handed
Potentially dangerous genes embedded within human DNA were once thought to be locked down by helpful DNA structures called heterochromatin. A University of Arizona researcher disputes that belief and hopes to change the paradigm even further. (2019-09-16)

Scientists created proteins controlled by light
Researchers developed fluorescent proteins that can be controlled by orange and green light. These proteins will help to study processes in living cells. The work was supported by Russian Science Foundation (RSF) grant, and the results were published in Nature Methods. (2018-09-28)

Time for total rethink on the management of alien species
A new study led by the University of Plymouth and the Marine and Environmental Research (MER) Lab in Cyprus is calling for a complete rethink of how non-indigenous or alien species are considered in the future (2020-11-26)

Fluorescent peptide nanoparticles, in every color of the rainbow
The discovery of green fluorescent protein (GFP), which is made by a jellyfish, transformed cell biology. It allowed scientists to stitch the GFP sequence to proteins from other organisms to trace their movements and interactions in living cells. Now, researchers reporting in ACS Applied Materials & Interfaces have designed peptide nanoparticles that can each glow in a variety of colors, opening the door for many new biomedical applications. (2020-07-08)

Singapore and US scientists uncover the structure of Wnt, Wntless proteins
Preventing Wnt from hitching a ride may offer new avenue for novel treatments for cancer and fibrosis. (2021-01-11)

Scientists pioneer microscopy technique that yields fresh data on muscular dystrophy
New microscopy technique yields resolution an order of magnitude better than previously possible. (2014-09-18)

Brown biologist wins NSF's Waterman Award
Biologist Casey Dunn is this year's winner of the National Science Foundation's Alan T. Waterman Award. Dunn's work on animal evolution and the origins of biological complexity, particularly with deep-sea creatures called siphonophores, holds clues for how complex multicellular organisms, including humans, were formed. (2011-03-14)

Clues contained in ancient brain point to the origin of heads in early animals
The discovery of a 500-million-year-old fossilized brain has helped identify a point of crucial transformation in early animals, and answered some of the questions about how heads first evolved. (2015-05-07)

Animals first flex their muscles
A new fossil discovery identifies the earliest evidence for animals with muscles. (2014-08-26)

Scientists discover new details about rice blast, a deadly plant fungus
An international team of researchers discover new information about how rice blast fungus invades plants. (2013-06-18)

Climate shifts shorten marine food chain off California
Environmental disturbances such as El NiƱo shake up the marine food web off Southern California, new research shows, countering conventional thinking that the hierarchy of who-eats-who in the ocean remains largely constant over time. (2017-10-19)

APS Division of Fluid Dynamics meeting: Highlights and media registration
The 64th Annual Meeting of the American Physical Society's Division of Fluid Dynamics will include more than 2,000 compelling presentations from across the physical sciences, engineering, and medicine. Topics include: explosions -- from tiny experiments to massive stars; the quirks of flying; why coffee spills; and how rain contributes to the spread of disease among plants. (2011-09-28)

Xenacoelomorpha -- a new phylum in the animal kingdom
Scientists reorganize the animal phylogenetic tree. (2011-02-16)

Scripps scientists discover fluorescence in key marine creature
Fluorescent proteins found in nature have been employed in a variety of scientific research purposes, from markers for tracing molecules in biomedicine to probes for testing environmental quality. Until now, such proteins have been identified mostly in jellyfish and corals, leading to the belief that the capacity for fluorescence in animals is exclusive to such primitive creatures. (2007-10-30)

Yerkes researchers develop first transgenic nonhuman primate model of Huntington's disease
For the first time, researchers have genetically modified a nonhuman primate and captured the clinical features observed in human patients. This study clearly shows nonhuman primate models have privileges over other animal models in terms of best capturing and studying human diseases. The ability to create transgenic nonhuman primate models opens more doors for thoroughly studying human diseases and conditions. Researchers are one step closer to finding better treatments as well as preventions and cures. (2008-05-18)

Revolutionary nanotechnology illuminates brain cells at work
Scientists at the Carnegie Institution's Department of Plant Biology and Stanford University are the first to accurately measure the levels of important chemicals in single brain cells in real time. They used a process known as fluorescence resonance energy transfer, or FRET, and introduced nanosensors into nerve cells to measure the release of the neurotransmitter glutamate -- the major brain chemical that increases nerve-cell activity in mammalian brains and contributes to diseases such as Alzheimer's and Parkinson's. (2005-05-30)

New book presents neurobiology from an evolutionary perspective
A new book, (2007-03-29)

Some of the biggest raindrops on record found in both clean and dirty air
On two occasions, separated by four years and thousands of miles and in very different conditions, raindrops were measured at sizes similar to or greater than the largest ever recorded. The largest ones were at least 8 millimeters in diameter and were possibly a centimeter. (2004-07-13)

Stingray In The Sky Sparks New Theory
Australian astronomers have put forward a new theory to explain a weird stingray shaped remnant of a giant exploded star or supernova. (1998-05-07)

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