Liver Failure Current Events

Liver Failure Current Events, Liver Failure News Articles.
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Animated short created to raise public awareness about liver failure
An animated short-film produced by the ALIVER consortium titled 'Life After Liver Failure' premieres tomorrow morning at the BioTech Village in The International Liver Congress™ 2018. (2018-04-11)

A bioartificial system acts as 'dialysis' for failing livers in pigs
A bioartificial system that incorporates enhanced liver cells can act as an analogous form of dialysis for the liver in pigs, effectively carrying out the organ's detoxifying roles and preventing further liver damage in animals with acute liver failure. (2020-07-08)

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells -- possibly dormant from the earliest developmental stage of a human being -- which have the potential to mature into different cells types and help repair a failing liver. (2006-07-06)

New test can predict death in patients with serious liver disease
Researchers from Aarhus University Hospital and Aarhus University in Denmark have found that the biomarker CD163 can predict mortality in blood samples from patients with acute on chronic liver failure. (2016-04-01)

Innovation in science
Results of a study presented today at the International Liver Congress 2010 demonstrate that a dual FXR and TGR5 agonist decreases liver damage and modulates hepatic inflammation and fibrosis in a mouse model of primary sclerosing chlolangitis. In contrast, selective FXR or TGR5 agonists have no beneficial effect. (2010-04-17)

Liver problems will likely increase in adults
A new study indicates that liver scarring (or fibrosis), which can ultimately lead to liver failure, is fairly common. It was especially prevalent in individuals with diabetes or steatosis, the latter of which occurs when fat cells infiltrate the liver. (2015-08-18)

Live donor liver transplantation found safe and effective for acute liver failure
When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly. (2015-03-19)

Children's Hospital of Pittsburgh to lead international study of acute liver failure in children
Children's Hospital of Pittsburgh Principal investigator Robert H. Squires Jr., MD, will lead a five-year, $5.8 million study recently funded by the National Institute of Diabetes and Digestive and Kidney Diseases. Children's is one of approximately 19 sites that will study acute liver failure in children. Acute liver failure is a rapidly developing clinical condition that results in either death or liver transplantation in 50 percent of the cases. (2005-09-28)

Research offers hope of new treatments for liver damage 'plague'
Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. There is currently no cure for liver cirrhosis and a patient's only hope of survival is to receive a liver transplant. (2005-01-05)

Research offers hope of new treatments for liver damage
Millions of patients suffering from liver damage (cirrhosis) and failure may benefit from research by the Universities of Edinburgh and Southampton which may lead to new life-saving treatments. (2005-03-24)

Liver fibrosis tied to specific heart failure, regardless of HIV or hepatitis C status
While there is an association between liver fibrosis and heart failure, the mechanisms for this association are currently unclear but may be of particular importance for people living with human immunodeficiency virus (HIV) and/or hepatitis C, both of which are chronic infections that affect the liver and heart. (2020-03-06)

Immunity study signals new ways to treat liver failure
Patients with liver failure could benefit from a treatment that helps the immune system to combat infections linked to the condition, University of Edinburgh research suggests. A study in mice has revealed that treatment with an immune-boosting molecule called CSF-1 helps to trigger the body's natural defense mechanisms in the liver. (2015-09-09)

U-M News: Kidney failure risk higher for liver transplant patients following policy change
Research from the University of Michigan Health System shows the risk for kidney failure among liver transplant recipients is higher following the implementation of Model of End Stage Liver Disease (MELD), a policy change in 2002 that altered how liver transplant allocation is decided. (2012-01-17)

Genetic variation may increase risk of liver damage in patients with chronic hepatitis B
A new study has shown that genetic variation may increase the risk of severe liver damage in Caucasians with chronic hepatitis B infection. (2018-07-26)

Liver study offers insights into hard-to-treat diseases
A key cell process that could cause damage to bile ducts and help explain some liver diseases has been identified by scientists. (2018-03-09)

International research network identifies triggers for severe course of liver cirrhosis
Acute-on-chronic liver failure (ACLF) is a common cause of death in patients with cirrhosis. In ACLF the progressive loss of function of the scarred liver can no longer be compensated (acute decompensation). As a result, other organs such as the kidney or brain fail. The triggers for acute decompensation of liver cirrhosis and an ACLF are most frequently bacterial infections, liver inflammation caused by alcohol, or a combination of both factors. (2021-02-02)

Serious liver-related condition on the rise in the US
A new analysis reveals that cirrhosis and acute on chronic liver failure (ACLF, a deterioration of liver function in patients with cirrhosis that results in the failure of one or more organs) represent a substantial and increasing health and economic burden in the United States. (2016-10-03)

UPMC Reports On New Liver Assist Device
Preliminary results of a new bio-artificial liver assist device were presented by University of Pittsburgh Medical Center (UPMC) researchers today at the 44th annual American Society for Artificial Internal Organs (ASAIO) conference in New York City. The device, designed by Excorp Medical Inc., significantly improved liver failure in animal studies, and researchers anticipate their results will help secure approval to begin studies in humans soon. (1998-04-23)

Treatment with NAC is associated with better outcomes for children with liver failure
A new retrospective study on the effects of N-acetylcysteine on children with acute liver failure not caused by acetaminophen poisoning has found that the treatment was associated with a shorter hospital stay, higher incidence of liver recovery, and better survival after transplantation. (2008-01-03)

New genetic screen paves the way for long-sought treatments for liver disease
Chronic liver failure is a major health problem that causes about one million deaths each year. A study published in Cell reveals a new type of screen for identifying genes that promote liver repair in mouse models of liver disease. The study shows that the MKK4 gene could be a promising therapeutic target to enhance liver regeneration and provides a blueprint for future studies aimed at discovering new therapies for liver disease. (2013-04-11)

Stopping liver failure from painkiller overdose
University of Adelaide researchers have identified a key step for the future prevention of liver failure resulting from taking too much of the everyday painkiller acetaminophenl (also known as paracetamol). (2014-02-04)

Paracetamol restrictions reduce overdose severity
Limiting the number of paracetamol tablets in a single packet has reduced the amount taken in single overdoses, but not the level of severe liver failure, according to a study in this week's BMJ. (2000-10-12)

UTHealth's Cynthia Ju awarded NIH grants for liver injury research
Tiny solutions are being sought for big liver problems by a scientist at McGovern Medical School at The University of Texas Health Science Center at Houston (UTHealth). (2019-12-20)

Liver surgery success boosted by growth hormone
Growth hormone has been identified as playing a key role in reducing inflammation and increasing survival rates following liver surgery. (2020-05-04)

Brazil faces major challenges in liver transplantation
A recent analysis indicates that more than 1,700 liver transplantations are performed annually in Brazil. While Brazil performs more liver transplant surgeries than anywhere else in Latin America and is third worldwide in absolute terms, the country averages only 5 to 10 liver transplants per million population due to its increasing population and inadequate donor organ supply. (2016-08-01)

Researchers devise index for predicting long-term survival after liver re-transplantation
UCLA researchers have identified eight risk factors for potential re-transplantation failure and, using mathematical modeling, developed a risk scoring system ranging from 0 to 12 to gauge the risk of re-transplantation failure. (2011-09-28)

Protein involved in blood clotting stimulates liver repair
A team of Michigan State University researchers, led by James Luyendyk in the College of Veterinary Medicine, has uncovered a new pathway in the body that stimulates liver repair. Using an experimental model of high-dosage acetaminophen, the team found that liver injury activated blood clotting, which then stimulated liver repair. The study is published online in the Journal of Hepatology. (2017-01-18)

CU researchers offer insights into liver disease caused by intravenous nutrition
University of Colorado School of Medicine's Karim C. El Kasmi, MD, PhD, assistant professor of pediatrics, and Ronald Sokol, MD, professor of pediatrics, are authors of an article in the April 2018 Nature Communications that sheds light on the underlying cause of intestinal failure-associated liver disease and suggests new therapeutic approaches. (2018-05-23)

UT Southwestern researchers say overdoses of acetaminophen cause most cases of acute liver failure
Unintentional acetaminophen overdose is the most common cause of acute liver failure in the United States, research from UT Southwestern Medical Center at Dallas shows. (2002-12-16)

Liver study could aid recovery of overdose patients
Scientists have identified a protein that they believe could hold the key to limiting liver damage following a paracetamol overdose. Researchers at the University of Edinburgh have found that overdose patients who suffer the greatest liver damage have higher levels of a protein known as cyclophilin A in their urine. (2008-12-16)

Study links obesity to liver failure
Researchers have found that obesity can put patients with acute liver failure at increased risk of mortality and other major complications, according to a new study presented today at Digestive Disease Week® 2006 (DDW). (2006-05-24)

International Meeting To Highlight Latest Developments In Liver Transplantation
Medical experts from around the world will gather Oct. 15 to 17 in Seattle for a review of state-of-the-art developments in liver transplantation at the Fourth Congress of the International Liver Transplantation Society (1997-09-23)

Fatality rates are high within 2 years of drug-induced liver injury
Most patients suffering liver toxicity due to medications or herbal or dietary supplements recover from the acute liver injury without long-term problems, but some do not survive the injury or they require liver transplantation. (2017-06-26)

Living donor liver transplants may drastically decrease mortality from liver failure
Patients with acute liver failure could be saved by a transplant from a living donor, according to a new study in the September issue of Liver Transplantation, a journal by John Wiley & Sons. The recent experience of US patients shows that recipient mortality rates and donor morbidity rates are acceptable. (2008-09-04)

Study examines liver transplantation after drug induced acute liver failure
Liver transplantation offers a good chance for survival for patients with drug induced acute liver failure, however, certain pre-transplant factors are associated with worse outcomes. (2009-07-01)

Drinking coffee may reduce the risk of liver cirrhosis
Regular consumption of coffee was linked with a reduced risk of liver cirrhosis in a review of relevant studies published before July 2015. (2016-02-01)

Global Liver Cancer Conference
This event brings international scientists together to fight liver cancer. It will be hosted over a span of two days. The first full day will be researchers sharing their knowledge, followed by a poster session. On the second day, a panel of physicians will share and learn the optimal medical and surgical management of liver cancer. (2015-03-02)

Molecular signatures may aid fight against pediatric liver disease
Researchers have identified a set of (2010-06-30)

Alcohol use in patients with chronic liver disease
A review article published in the New England Journal of Medicine discusses the effects of alcohol use on various forms of liver disease, as well as the assessment and treatment of alcohol use in patients with chronic liver disease. (2018-09-26)

Medication effective for acute liver failure in early stages of disease
The antidote for acute liver failure caused by acetaminophen poisoning also can treat acute liver failure due to most other causes if given before severe injury occurs, UT Southwestern Medical Center researchers and their colleagues at 21 other institutions have found. (2009-10-08)

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