Liver Transplantation Current Events

Liver Transplantation Current Events, Liver Transplantation News Articles.
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International Meeting To Highlight Latest Developments In Liver Transplantation
Medical experts from around the world will gather Oct. 15 to 17 in Seattle for a review of state-of-the-art developments in liver transplantation at the Fourth Congress of the International Liver Transplantation Society (1997-09-23)

Brazil faces major challenges in liver transplantation
A recent analysis indicates that more than 1,700 liver transplantations are performed annually in Brazil. While Brazil performs more liver transplant surgeries than anywhere else in Latin America and is third worldwide in absolute terms, the country averages only 5 to 10 liver transplants per million population due to its increasing population and inadequate donor organ supply. (2016-08-01)

Heavy drinking endangers the health of liver transplants
Alcoholic liver disease is a major indication for liver transplantation, but up to 20 percent of patients experience severe alcoholic relapse. New research shows that such relapse can cause significant damage to newly transplanted livers. (2016-04-07)

Study's findings could help expand the donor pool for liver transplantation
Organ donation after circulatory death, in which transplant organs are taken from donors after ay period of no blood circulation or oxygenation, is often considered inferior to donation after brain death, in which circulation and oxygenation are maintained until organs are removed for transplantation (2015-09-08)

Cedars-Sinai surgeon and policymaker honored for work in liver disease and transplantation
Andrew S. Klein M.D., M.B.A., director of the Cedars-Sinai Comprehensive Transplant Center is being honored for a lifetime of achievement in the field of liver transplantation by the Los Angeles chapter of the American Liver Foundation. (2014-05-01)

Use of opioid pain medications may affect liver transplant patients' survival
An analysis of nearly 30,000 patients undergoing liver transplantation in the United States between 2008 and 2014 found elevated death and organ loss rates in the first five years after transplantation among recipients with the highest use of opioid pain medications while on the waiting list. (2017-03-02)

Fatality rates are high within 2 years of drug-induced liver injury
Most patients suffering liver toxicity due to medications or herbal or dietary supplements recover from the acute liver injury without long-term problems, but some do not survive the injury or they require liver transplantation. (2017-06-26)

Women, blacks, Medicare recipients less likely to be evaluated for liver transplantation
Patient race, gender and insurance status influence decisions about who will go on to receive liver transplants, according to a University of Pittsburgh School of Medicine study. Available online and published in the September issue of the American Journal of Transplantation, the study indicates that women, blacks and patients with Medicare who are in end-stage liver disease are less likely to be referred and evaluated for liver transplantation. (2009-08-31)

Live donor liver transplantation found safe and effective for acute liver failure
When patients develop acute liver failure, severe complications arise rapidly after the first signs of liver disease, and patients' health can deteriorate rapidly. (2015-03-19)

Livers from non-heart beating donors would boost organ supply
Liver transplants from non-heart beating donors have the potential to increase the supply of organs by as much as 20 percent, according to experts in this week's BMJ. (2006-02-16)

Researchers devise index for predicting long-term survival after liver re-transplantation
UCLA researchers have identified eight risk factors for potential re-transplantation failure and, using mathematical modeling, developed a risk scoring system ranging from 0 to 12 to gauge the risk of re-transplantation failure. (2011-09-28)

A bioartificial system acts as 'dialysis' for failing livers in pigs
A bioartificial system that incorporates enhanced liver cells can act as an analogous form of dialysis for the liver in pigs, effectively carrying out the organ's detoxifying roles and preventing further liver damage in animals with acute liver failure. (2020-07-08)

Early promise for steroid-free liver transplantation in children
Results of a preliminary study into paediatric liver transplantation in this week's issue of The Lancet suggest that successful transplantation could take place without the need for steroid treatment-with potential health benefits for transplant recipients. (2003-12-18)

Animated short created to raise public awareness about liver failure
An animated short-film produced by the ALIVER consortium titled 'Life After Liver Failure' premieres tomorrow morning at the BioTech Village in The International Liver Congress™ 2018. (2018-04-11)

Innovation in science
Results of a study presented today at the International Liver Congress 2010 demonstrate that a dual FXR and TGR5 agonist decreases liver damage and modulates hepatic inflammation and fibrosis in a mouse model of primary sclerosing chlolangitis. In contrast, selective FXR or TGR5 agonists have no beneficial effect. (2010-04-17)

Researchers aim to cut future need for liver transplants
University of Edinburgh scientists have identified primitive liver cells -- possibly dormant from the earliest developmental stage of a human being -- which have the potential to mature into different cells types and help repair a failing liver. (2006-07-06)

Liver transplant recipients with hepatitis B may need lifelong antiviral treatment
Patients who undergo liver transplantation for hepatitis B-related liver damage should receive lifelong antiviral treatment to keep the disease from coming back. A new study shows that they lack cellular immunity against the disease, making recurrence likely if antiviral treatment is withdrawn. These findings are in the March issue of Liver Transplantation, a journal published by John Wiley & Sons. (2009-02-26)

Children's Hospital physicians publish review of transplant issues in patients with biliary atresia
The most common indication worldwide for pediatric transplantation, biliary atresia is also the most common cause of chronic liver disease in newborns. Recently, Children's Hospital of Pittsburgh of UPMC physicians completed a review of issues that children with biliary atresia face that lead to the need for transplantation. (2008-01-08)

Drug Combination May Prove Effective To Prevent Recurrence Of Hepatitis C After Transplantation
Hepatitis C is the most common indication for liver transplantation, yet it recurs in almost all patients and cannot be treated. A preliminary study of liver transplant recipients treated with a combination of drugs for a year after their transplants suggests the therapy can be effective in eradicating the virus. (1998-11-05)

Nerve damage from alcoholism reversed after liver transplantation
A new study describes a patient with alcoholic liver disease complicated by peripheral neuropathy (nerve damage affecting the arms and legs) who underwent a liver transplant and regained almost normal muscle strength. (2004-12-01)

Study reveals improving survival rates after liver transplantation in the UK
In the past two decades, death rates after liver transplantation have dropped by more than half in the UK, according to a recent analysis of almost 10,000 liver transplant recipients published in BJS (British Journal of Surgery). (2020-03-04)

Artery variations increase complication risk in liver transplants
3D MDCT angiography is a more efficient way to classify liver arterial anatomy before liver surgery, according to researchers from Duke University in Durham, NC. In a separate study, University of Iowa researchers have found that using MR angiography before a liver transplant can help identify which patients will suffer complications. The study found that if the liver artery anatomy is unusual, there is an increased risk of complications after the transplant procedure. (2004-12-02)

Not just small adults: Pediatric liver transplant recipients need special care
A new review discusses important consideration when caring for children who have received liver transplants. (2017-01-17)

Survival rates higher for children receiving living donor liver transplant
Children who undergo liver transplantation have better survival rates with living donor liver transplant graft than with deceased donor organ transplant, although factors other than the type of graft also are important, according to a study in the May issue of Archives of Surgery, one of the JAMA/Archives journals. (2005-05-16)

Protein predicts liver cancer recurrence and after transplantation
A new study suggests that Capn4, a protein involved in cell migration, is associated with liver cancer recurrence and metastasis after liver transplantation. Capn4 could potentially be used as a biomarker for diagnosis and a target for therapy. (2009-02-03)

Lower tacrolimus doses is suitable for living donor liver transplantation with small-for-size graft
Tacrolimus (FK506) is a potent immunosuppressive agent widely used in organ transplantation. A research group in China investigated the tacrolimus dosage requirements in small-for-size (SFS, graft-recipient body weight ratio less than 0.8 percent) liver grafts in adult to adult right lobe living donor liver transplantation. The research revealed that SFS grafts had significantly decreased tacrolimus dosage requirements compared with non-SFS graft recipients during the first two months post-surgery in spite of having similar tacrolimus concentrations. (2009-08-26)

New technique improves outcome for living donor liver transplants
Thanks to a review paper done at the University of Alberta radiologists at the University of Alberta Hospital are now using CT imaging for living-donor liver transplantation. CT imaging allows surgeons to plan the operation more accurately, which increases the likelihood for organ graft survival in recipients and reduces complication rates in donors. (2008-03-18)

Inhaling helps heal liver transplant recipients
A new study indicates that one of the main complications of liver transplantation can be treated very simply. Inhalation of nitrous oxide during the transplant operation decreased the length of time patients had to stay in hospital and increased the rate at which the function of the transplanted liver was restored. The authors therefore suggest that inhalation of nitrous oxide is a valuable pre-emptive approach to enhancing liver function after transplantation. (2007-08-23)

Successful pregnancies possible for women following liver transplantation
New research confirms that successful pregnancies are common for female liver transplant recipients. (2012-06-07)

The immune system's role in hepatitis C recurrence after liver transplantation
A new study pinpoints certain aspects of the immune system that may play a role in the recurrence and progression of hepatitis C virus after liver transplantation. (2009-04-01)

OHSU researchers use stem cells to repair liver damage in mice
Researchers at Oregon Health Sciences University and colleagues have determined that certain specialized stem cells can cause healthy liver cell growth in mice. The result may be new therapies and reduced whole organ liver transplantation in humans with liver disease. (2000-11-12)

Children's Hospital of Pittsburgh to lead international study of acute liver failure in children
Children's Hospital of Pittsburgh Principal investigator Robert H. Squires Jr., MD, will lead a five-year, $5.8 million study recently funded by the National Institute of Diabetes and Digestive and Kidney Diseases. Children's is one of approximately 19 sites that will study acute liver failure in children. Acute liver failure is a rapidly developing clinical condition that results in either death or liver transplantation in 50 percent of the cases. (2005-09-28)

Liver transplant offers survival benefits for patients of all sizes
Patients with high BMIs experience a significant survival benefit from liver transplantation and had similar rates of mortality after transplant compared to patients with normal BMI. (2007-12-04)

Emory University Surgeons Perform Georgia's First Split Liver Transplant
Emory Unviversity surgeons successfully split a donated cadaveric liver into two portions, giving both a child and an adult a new chance at life. (1997-10-14)

Acute kidney injury common after liver transplantation
Even mild cases of acute kidney injury after liver transplantation are associated with lower survival for both the patient and the graft. With more severe injury, outcomes are even worse. These findings are in the May issue of Liver Transplantation, a journal published by John Wiley & Sons. (2009-05-04)

Many young children with liver failure die while waiting for a transplant or soon after receiving one
A new analysis reveals unacceptable mortality rates in young US children with chronic liver disease while they are on transplant waiting lists as well as after transplantation. (2016-10-27)

Racial disparity studied in patients undergoing liver transplantation for hepatitis B
According to the Centers for Disease Control and Prevention, 1.5 to 2 million Americans are infected with the hepatitis B virus. Prior studies have shown there to be significant racial differences in access to and outcomes of liver transplantation. Recently, doctors from across the US conducted a multicenter retrospective-prospective study of the waitlist status and outcomes of liver transplant patients with HBV infection. (2009-08-28)

Liver transplant may arrest neurological damage in a rare and progressive form of autism
A patient with a rare metabolic disease that causes liver failure and autistic behavior experienced significant improvements in both her physical and mental health after receiving a liver transplant, according to a new case report published in the American Journal of Transplantation. (2014-03-12)

Hepatitis C recurrence after liver transplantation
Hepatitis C recurs with severity more often in individuals who receive liver transplants from living donors compared with those who get transplants from cadavers, according to a new study published in the September 2004 issue of Hepatology. (2004-09-09)

Jefferson doctor named transplant surgeon of the year
The Delaware Valley Chapter of the American Liver Foundation recently named Cataldo Doria, M.D., Ph.D., associate professor of Surgery at Jefferson Medical College of Thomas Jefferson University and director of the Division of Transplantation at Thomas Jefferson University Hospital, (2008-10-22)

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