Longevity Current Events

Longevity Current Events, Longevity News Articles.
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APOB, a gene involved in lipid transport, linked to cases of familial extreme longevity
In a recent report in Aging Cell, a multidisciplinary team of Spanish scientists, led by Tim Cash and Manuel Serrano at the Spanish National Cancer Research Centre, identify rare variants in the APOB gene in several families where exceptional longevity (>100 years of age) appears to cluster. (2014-08-25)

New genes associated with extreme longevity identified
Centenarians show successful aging as they remain active and alert at very old ages. Scientists at Stanford University and the University of Bologna have begun to unravel the basis for longevity by finding genetic loci associated with extreme longevity. The report by Kristen Fortney and colleagues, published in PLOS Genetics, uses a new statistical method (termed 'informed GWAS') to identify five longevity loci that provide clues about physiological mechanisms for successful aging. (2015-12-17)

A Gene Involved in Regulating Longevity in Worms May Provide a Clue to Human Aging
Discovery of a mutant gene involved in the regulation of longevity of a primitive worm, C. elegans, may provide a clue as to how humans age. Normal development and longevity in the worm C. elegans are regulated by the age-1 gene. Lack of age- 1 activity in adult worms, due to mutations in the age-1 gene, results in a doubling of adult life span. (1996-08-08)

BGRF hosts inaugural 21st Century Medicine Forum
The Biogerontology Research Foundation, a UK-based charity founded to support ageing research and address the challenges of a rapidly ageing population, hosted the inaugural 21st Century Medicine Forum on Monday, June 30th, with Aging Analytics, a company supporting financial decision-making in the biotechnology and regenerative medicine sector. (2014-07-14)

Scientists have found longevity biomarkers
An international group of scientists studied the effects of 17 different lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal Cell Metabolism. (2019-08-23)

Study suggests why some animals live longer
Scientists at the University of Liverpool have developed a new method to detect proteins associated with longevity, which helps further our understanding into why some animals live longer than others. (2012-03-29)

New book on 'Aging: The Longevity Dividend' from Cold Spring Harbor Laboratory Press
'Aging: The Longevity Dividend' from CSHLPress, examines the biological basis of aging, strategies that may extend health span, and the societal implications of delayed aging. Contributors discuss genetic variants that accelerate or protect against aging, biochemical pathways that modulate longevity (e.g., mTOR), biological consequences of aging (e.g., decline in stem cell function), and various animal models used to study aging processes. They emphasize that age-delaying interventions will yield greater health and vitality than disease-specific treatments. (2015-12-17)

Researchers predict pensions catastrophe
Recent increases in our longevity could have disturbing implications for the government, pension companies and life insurance industries. (2007-11-29)

Einstein researchers use novel approach to uncover genetic components of aging
People who live to 100 or more are known to have just as many -- and sometimes even more -- harmful gene variants compared with younger people. Now, scientists at the Albert Einstein College of Medicine of Yeshiva University have discovered the secret behind this paradox: favorable (2007-08-24)

Study finds new genetic variants associated with extreme old age
The search for the genetic determinants of extreme longevity has been challenging, with the prevalence of centenarians (people older than 100) just one per 5,000 population in developed nations. But a recently published study by Boston University School of Public Health and School of Medicine researchers, which combines four studies of extreme longevity, has identified new rare variants in chromosomes 4 and 7 associated with extreme survival and with reduced risks for cardiovascular and Alzheimer's disease. (2017-04-25)

Low vitamin D levels associated with longevity
Low levels of vitamin D may be associated with longevity, according to a study involving middle-aged children of people in their 90s published in CMAJ (Canadian Medical Association Journal). (2012-11-05)

NIH awards Einstein multimillion dollar grant to extend studies of exceptional longevity
Albert Einstein College of Medicine of Yeshiva University has been awarded a grant of more than $9.25 million from the National Institutes of Health to further the medical school's study of centenarians and the biology of aging. (2007-09-17)

Nutraceuticals for promoting longevity
The review, published in Current Nutraceuticals, offers a special focus on the nutraceuticals that impact insulin-like growth factor 1 receptor signaling and sirtuin activity in mediating longevity and healthspan. (2020-06-10)

Role of life's timekeeper -- a novel theory of animal evolution
This novel research disputes modern interpretations of Darwin's theory, though probably remains compatible with Darwin's original hypothesis. (2016-04-25)

New findings suggest a genetic influence on aging into the 90s but not beyond
Variants of a gene thought to be linked to longevity appear to influence aging into the 90s, but do not appear to affect exceptional longevity, or aging over 100, a new study has found. (2017-07-18)

845-Page analytical report on the longevity industry in the UK released
The Biogerontology Research Foundation announces the publication of a new analytical report titled Longevity Industry in UK Landscape Overview 2018. (2018-07-31)

The bowhead whale lives over 200 years. Can its genes tell us why?
A whale that can live over 200 years with little evidence of age-related disease may provide untapped insights into how to live a long and healthy life. In the Jan. 6 issue of Cell Reports, researchers present the complete bowhead whale genome and identify key differences compared to other mammals. Alterations in bowhead genes related to cell division, DNA repair, cancer, and aging may have helped increase its longevity and cancer resistance. (2015-01-05)

Scientist proposes new theory of aging
Birds do it, bees do it, and yes, even chimpanzees do it. They all dote on their young. And now a new theory of aging suggests that nurturing offspring is just as important as fertility and reproduction for the evolution of a species' longevity and long-term survival. (2003-07-14)

Going to the dogs: What can shy dogs teach us about longevity?
According to a new study by a Quebec research team, there are strong correlations between dog breeds' typical personalities, how long they live, and how much food they eat. (2010-05-13)

Most mammals have a greater life expectancy in zoos
Life in the wild harbors the risk of predation, food shortages, harsh climates, and intense competition. Zoo animals, by contrast, are protected from these dangers. UZH researchers were part of an international team that studied over 50 mammalian species to determine whether the animals live longer in zoos than in the wild. (2016-11-07)

The whole-genome sequences of the world's oldest living people published
Using fewer than 20 genomes, researchers were unable to find rare protein-altering variants significantly associated with extreme longevity. (2014-11-12)

Scientists publish a blueprint to apply artificial intelligence to extend human longevity
The international team of artificial intelligence experts and medical doctors propose a framework for the application of next-generation AI to extend human longevity (2021-01-27)

BGRF trustees present at Financial Times and The Economist Longevity Conferences
Biogerontology Research Foundation Trustee Dmitry Kaminskiy and Chief Science Officer Alex Zhavoronkov spoke at the Aging and Longevity Panel at the Financial Times Global Pharmaceutical and Biotechnology Conference on Nov. 10th, 2017, alongside Aubrey de Grey, Chief Science Officer of SENS Research Foundation, and Joseph Antoun, Chairman of the Global Healthspan Policy Institute. (2017-11-27)

New study suggests US presidents often live longer than men of their era
In a research letter appearing in the Dec. 7 issue of JAMA, S. Jay Olshansky, Ph.D., of the University of Illinois at Chicago, examined the question that U.S. Presidents may experience accelerated aging while in office by analyzing the life span of all US Presidents compared to men of their era. (2011-12-06)

Blocking pain receptors found to extend lifespan in mammals
Chronic pain in humans is associated with worse health and a shorter lifespan, but the molecular mechanisms underlying these clinical observations have not been clear. A study published in Cell reveals that the activity of a pain receptor called TRPV1 regulates lifespan and metabolic health in mice. The study suggests that pain perception can affect the aging process and reveals novel strategies that could improve metabolic health and longevity in humans. (2014-05-22)

Is the 'longevity gene' nearing the end of its life?
Sirtuins, proteins believed to significantly increase lifespan in a number of organisms -- and the claimed target of some anti-aging creams -- do not, in fact, affect animal longevity, according to new research funded by the Wellcome Trust and the European Union. (2011-09-21)

Researchers identify personality traits
Researchers from Boston University School of Medicine's New England Centenarian Study have noted specific personality traits associated with healthy aging and longevity amongst the children of centenarians. The work was conducted in collaboration with scientists from the National Institute on Aging. These findings currently appear online in the Journal of the American Geriatrics Society. (2009-04-03)

BU/BMC study finds the role of genes is greater with living to older ages
Genes appear to play a stronger role in longevity in people living to extreme older ages, according to a study of siblings led by Boston University and Boston Medical Center researchers. (2015-03-26)

Living longer and happier
A new study from the University of Missouri may shed light on how to increase the level and quality of activity in the elderly. In the study, published in this week's edition of PLoS ONE, MU researchers found that gene therapy with a proven (2009-08-19)

Researchers at Illinois explore queen bee longevity
The queen honey bee is genetically identical to the workers in her hive, but she lives 10 times longer and -- unlike her sterile sisters -- remains reproductively viable throughout life. A study from the University of Illinois sheds new light on the molecular mechanisms that account for this divergence. The study appears in the online edition of the Proceedings of the National Academy of Sciences. (2007-05-08)

Preserving memory with age
If you lived longer, would you still remember everything? It depends. Two methods of extending life span have very different effects on memory performance and decline with age, researchers at Princeton University have shown in a study publishing next week in the online, open-access journal PLoS Biology. (2010-05-18)

Ecologist wins international award
Dr. Justin Congdon, a senior research ecologist with the Savannah River Ecology Laboratory, has been awarded the 2000 Longevity Prize by the Fondation IPSEN, a French organization that supports work in the field of longevity. (2000-12-10)

'Biology of Aging' -- New textbook now available
Garland Science is proud to announce the publication of the new textbook Biology of Aging by Roger B. McDonald. Biology of Aging presents the biological principles that have led to a new understanding of the causes of aging and describes how these basic principles help one to understand the human experience of biological aging, longevity, and age-related disease. (2013-07-11)

High number of test match appearances linked to longer life
The more test matches a cricketer plays, the longer he is likely to live, suggests research published ahead of print in the British Journal of Sports Medicine. (2008-04-09)

One percent reduction in cancer mortality would be worth nearly $500 billion
Even a modest one percent reduction in mortality from cancer would be worth nearly $500 billion in social value, according to a new study by economists Kevin Murphy and Robert Topel of the University of Chicago Graduate School of Business. Finding a cure for cancer would be worth about $50 trillion. (2006-04-04)

Deep Longevity publishes an epigenetic aging clock of unprecedented accuracy
Longevity startup ''Deep Longevity'' has released a new high-accuracy methylation aging clock -- DeepMAge. It is a neural network that was trained and verified in a collection of >6,000 blood samples from 32 studies. The median absolute error of this aging clock is superior to other methylation clocks: 2.77 years in healthy people. The clock shows association with multiple age-related conditions, including cancer, dementia, and obesity. The authors aim to further develop DeepMAge into a generative model to simulate subcellular aging processes. (2020-12-08)

Scientists publish the first human psychological aging clock using artificial intelligence
Scientists at Deep Longevity published the first set of psychomarkers of aging developed using deep learning to track the changes in human psychology and assess the effectiveness of interventions, life events, and external events. The new PsychoAge and SubjAge aging clocks were linked to mortality risk. (2020-12-16)

Reproduction and life span are intertwined
Removal of germ cells -- the sperm and egg producing cells -- increases longevity of the roundworm. Now scientists at the Max Planck Institute for Biology of Ageing, have discovered that germ cell removal flips a (2012-12-17)

New study identifies possible predictor for women's longevity
Death and taxes have long been said to be the only two things guaranteed in life. Exactly when someone will die, in most instances, remains a mystery. A new study, however, identifies one possible predictor -- specifically, telomere length. This has been linked to longevity, as well as the ability to bear children at an older age. The study is being published online today in Menopause, the journal of the North American Menopause Society. (2016-12-07)

Older first-time mothers are also more likely to live longer
The average age of a woman giving birth for the first time has risen dramatically in the United States over the past 40 years, driven by factors like education or career. A new study by researchers at University of California San Diego School of Medicine found that women choosing to become first-time mothers later in life may increase their chances of living into their 90s. (2016-11-17)

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