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Macrophages Current Events, Macrophages News Articles.
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Immune cells play a role in early pregnancy
In this issue of the Journal of Clinical Investigation, Sarah Robertson and colleagues at the University of Adelaide investigated the role of macrophages in early pregnancy. (2013-07-08)
Tuning macrophages a 'breakthrough' in cancer immunotherapy
A University of Colorado Cancer Center article in the journal Cancer Research describes 'tuning' macrophages from ones that repair wounds (and contribute to tumor growth) to ones that sterilize wounds (and contribute to the immune system's attack of tumor tissue). (2016-02-04)
Silence is golden -- Suppressing host response to Ebola virus may help to control infection
The Ebola virus causes a severe, often fatal illness when it infects the human body. (2017-03-22)
Retraining immune cells to kill tumors
Tumors escape destruction by immune cells by turning off their tumor killing functions. (2008-05-19)
Drug targeting technique could aid therapies for immune diseases
A new technique that targets drugs to specific cells could lead to improved therapies for diseases caused by an overactive immune response. (2017-09-25)
Scientists shed new light on the fight against cancer
The Leuven-based VIB researchers have revealed a mechanism that explains why the anti-tumor activity of specific immune cells called macrophages is suppressed during tumor growth. (2013-12-10)
Key immune system protein reduced in HIV-associated dementia patients
Researchers at the San Francisco Veterans Affairs Medical Center and UCSF have discovered that an important protein normally secreted by macrophages, the scavenger cells of the immune system, is secreted at significantly reduced levels in patients with HIV-related dementia. (2004-05-19)
Why macrophages rest in healthy tissue
ETH scientists have shown that the immune system's macrophages are regulated not only biochemically, but mechanically as well. (2018-11-20)
New path of origin for macrophages
Macrophages play a key role in the immune response. They differ depending on where they are located and which tasks they perform. (2012-05-02)
Late invasion of infected cells into the brain causes HIV dementia say Temple researchers
Dementia in AIDS patients is caused by a large, late invasion of HIV-infected macrophages into the brain, debunking a longstanding (2004-06-04)
Boosting the anti-inflammatory action of the immune system
Researchers have identified a molecular switch that causes macrophages to clean up cellular debris caused by infections instead of contributing to inflammation and tissue injury. (2019-07-30)
New Finding Underscores Importance Of Controlling Opportunistic Infection
One of the many questions surrounding AIDS has been where HIV comes from in the latter stages of the disease, when the patients have low CD4 T cell counts. (1997-06-19)
Uncovering the mechanisms that support the spread of ovarian cancer
In this issue of the JCI, research led by Wang Min at Yale University describes how a subtype of macrophages communicate with and support tumor cell growth to drive metastasis in ovarian cancer. (2016-10-10)
'Cells-soldiers' turned to be more resistant than 'cells-combat medics'
Researchers from Sechenov University (Russia) and University of Pittsburgh (USA) discovered that the resistance of innate immune cells, macrophages, to ferroptosis -- a type of programmed cell death -- depends on the type of their activation. (2020-05-16)
UNC researchers identify a new HIV reservoir
A UNC research team has identified a new cell in the body where HIV persists despite treatment. (2017-04-17)
Temple virologist receives NIH grant to continue investigation of HIV dementia complex
Temple University virologist Jay Rappaport has been awarded a five-year, $2 million grant from the National Institutes of Health to continue his research into how AIDS patients develop dementia. (2004-06-02)
Immune cells proposed as HIV hideout don't last in primate model
New research from Yerkes National Primate Research Center, Emory University, sheds light on the question of which cells support viral replication and persistence, and the answers have implications for future efforts to eliminate HIV from the body in human patients. (2014-10-31)
Immune cells essential to establishing pregnancy
New research from the University of Adelaide shows for the first time that immune cells known as macrophages are critical to fertility by creating a healthy hormone environment in the uterus. (2013-07-08)
How the tuberculosis bacterium tricks the immune system
Scientists at EPFL have discovered how the tuberculosis bacterium can trick the patient's immune cells to lower their defenses. (2015-06-02)
Scientists reveal link between cell metabolism and the spread of cancer
A team led by Massimiliano Mazzone has demonstrated that the metabolism of macrophages, a particular type of white blood cell, can be attuned to prevent the spread of cancer. (2016-10-20)
Macrophages from human lymphoma patients cause mouse lymphoma in mice, UCSF study finds
UCSF researchers have found that macrophages when taken from HIV-infected lymphoma patients and injected into mice, induced aggressive mouse T-cell lymphomas in the mice. (2002-09-30)
Air pollution thickens the blood
Air pollution, and especially particulate matter, thickens the blood and boosts inflammation, finds experimental research in Occupational and Environmental Medicine. (2005-02-20)
Discovery of long-lived macrophages in the intestine
Macrophages are specialised immune cells that destroy bacteria and other harmful organisms. (2018-08-30)
Funding for animal testing alternative
A researcher from Plymouth University Peninsula Schools of Medicine and Dentistry has received an award of £ 94,365 (Sterling) from the National Centre for the Replacement, Refinement and Reduction of Animals in Research, for a pilot study to develop the lab-based creation of a type of mouse cell which could be used in place of the live animals for research related to infectious and allergic lung conditions. (2013-08-23)
Insights into how TB tricks the immune system could help combat the disease
Researchers have identified a potential way to manipulate the immune system to improve its ability to fight off tuberculosis (TB). (2013-10-23)
Genetic factor controls health-harming inflammation in obese
Researchers at Case Western Reserve University School of Medicine have discovered a genetic factor that can regulate obesity-induced inflammation that contributes to chronic health problems. (2011-06-13)
HIV/tuberculosis co-infection: Tunneling towards better diagnosis
1.2 million people in the world are co-infected by the bacteria which causes tuberculosis and AIDS. (2019-03-26)
Testicular macrophages are guardians of fertility
The origin, development, and characteristics of two types of testicular macrophage have been described by a CNRS team at the Centre d'Immunologie de Marseille-Luminy. (2017-08-11)
Steering cancer inflammation to inhibit tumor growth and spread
Most cancer tissues are invaded by inflammatory cells that either stimulate or inhibit the growth of the tumor, depending on what immune cells are involved. (2011-01-06)
UNC School of Medicine researchers prove HIV targets tissue macrophages
Investigators in the Division of Infectious Diseases at the University of North Carolina School of Medicine have clearly demonstrated that HIV infects and reproduces in macrophages, large white blood cells found in the liver, brain and connective tissues of the body. (2016-03-08)
Zika infection of placental macrophages in culture
In this issue of JCI Insight, Erol Fikrig and colleagues at Yale University examined Zika virus infection of different cell types of the placenta, including cytotrophoblasts, placental macrophages, and fibroblasts. (2016-08-18)
Study shows how HIV breaches macrophage defenses, could be step towards cure
A team led by UCL researchers has identified how HIV is able to infect macrophages, a type of white blood cell integral to the immune system, despite the presence of a protective protein. (2017-01-25)
Neuron guidance factor found to play a key role in immune cell function
Macrophages are white blood cells that perform different functions with different energy needs. (2018-05-20)
Macrophage population activates repair in murine heart attack model
In this month's issue of the JCI, a team led by Ken Suzuki at the William Harvey Research Institute determined that tissue reparation after a heart attack depends on the production of a type of white blood cell called M2 macrophages. (2016-05-03)
Growing lymph vessels with macrophages? Surprisingly, yes!
When the cornea is inflamed, blood and lymphatic vessels grow into this normally avascular area. (2005-09-01)
Macrophage accumulation of triglycerides yields insights into atherosclerosis
A research report appearing in the Journal of Leukocyte Biology (http://www.jleukbio.org) helps explain how specific immune cells, called macrophages, accumulate triglycerides to support their function. (2012-10-01)
UCSB researchers discover shape matters to macrophages
Researchers at UC Santa Barbara have made a surprising discovery: phagocytosis depends more on particle shape than size. (2006-03-21)
New test can predict death in patients with serious liver disease
Researchers from Aarhus University Hospital and Aarhus University in Denmark have found that the biomarker CD163 can predict mortality in blood samples from patients with acute on chronic liver failure. (2016-04-01)
Researchers further illuminate pathway for treatment of cystic fibrosis
By studying alveolar macrophages, which provide our airways with a crucial defense against pathogens, UNC scientists are now able to more fully understand the larger picture of CF symptoms and continue progress towards targeted treatments, aside from addressing the mutated CFTR gene. (2016-01-12)
Findings identify receptors modulating macrophage responses to spinal cord injury
A study by researchers at the University of Kentucky and the Ohio State University sheds light on opportunities to modulate macrophage responses after spinal cord injury, potentially reducing -- or even reversing -- damage and the resulting side effects. (2015-07-10)
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