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Magic enzymes
Little fungi pack a punch: 'Magic mushrooms' of the Psilocybe species produce psychoactive compounds that alter perception when ingested. Recently, the effects on the neuronal system caused by their ingredient psilocybin have attracted the interest of pharmacologists. German scientists have now identified four of the enzymes responsible for the biosynthesis of psilocybin. In the journal Angewandte Chemie, they describe the biosynthetic pathway and introduce a synthetic route that could form the basis of biotechnological production. (2017-08-25)

105-day Mars simulation: US studies focus on improving work performance
For 105 days, a six-man crew called an isolation chamber in Moscow their home. The crew simulated a Mars mission full of experiments and realistic mission scenarios. US participation consisted of three research teams with experiments evaluating solutions to conditions that impact work performance: lighting interventions to counter shift-work sleep loss, tests measuring the impact of stress and fatigue on performance, and assessing interactions between crew members and mission control. (2009-07-13)

Overly tired teen? Sleepiness may signal serious health problem
In a major new report in Pediatrics, doctors who care for young adults are warned that computer games and caffeine may not be the only sources of teen sleep deprivation. Sleep apnea, depression and other medical disorders could be to blame, according to the report by Richard Millman, M.D., and other researchers at Brown University. The report has been endorsed by the American Academy of Pediatrics. (2005-06-06)

Nocturnal alertness improves after exposure to milliseconds of bright light flashes
Subjective sleepiness decreased and objective nighttime alertness improved after participants received a two-millisecond pulse of bright light once per minute for 60 minutes. Flash exposure, as compared with darkness, elicited significant improvement in self-rated alertness and a significant 57-millisecond improvement in median reaction time on the auditory Psychomotor Vigilance Test, compared with no significant improvement after 60 minutes of darkness. The randomized crossover study involved seven people who were tested two times. (2010-06-07)

Study shows rapid growth in neuroscience research
A study of the impact and research topics of neuroscience papers from 2006-2015 has shown that the number of neuroscience papers and highly-productive core neuroscience journals has grown, while psychology and behavioral sciences have become more popular research areas. China has emerged as a major neuroscience contributor, with a jump in the list of the most productive countries for neuroscience research from 11th place in 2006 to 2nd place in 2015. (2017-04-20)

Electro-acupuncture for disrupted sleep in women with breast cancer
It's somewhat of a little-known adverse effect of having breast cancer, but studies suggest that approximately 30 percent to 40 percent of women with breast cancer report persistent hot flashes. Nocturnal hot flashes are among the most problematic because they can contribute to poor sleep. (2016-11-28)

Journal of Clinical Sleep Medicine collection highlights 15 years of scientific discovery
Editors of the Journal of Clinical Sleep Medicine have identified some of the most significant articles in the publication's history, publishing new commentaries on them in a special 15th anniversary collection. The 15 commentaries from associate editors and members of the journal's editorial board describe the impact of the selected articles both at the time of their publication and today. (2021-01-14)

Research suggests unborn children may be at risk from environmental pollution
New research presented at a conference on 6 Monday September in London shows that harmful environmental agents can cross the placenta to reach the developing foetus. (2004-09-06)

Circadian rhythms: Their role and dysfunction in affective disorder
Biological clocks play a major role in affective disorders. Synchronizing impaired circadian rhythms, improving sleep, or paradoxically staying awake most of the night can be extremely helpful to treat patients with depression and bipolar disorder. Chronotherapeutic combinations of light and wake therapy achieve fast results and also minimize relapse over many months. Chronotherapeutics seem to be a major facilitator of drug response, and, in combination with antidepressants, a promising method to stabilize patients over the long term. (2010-08-30)

Moving light-dark exposure could reduce disruption faced by night shift workers
New research published in The Journal of Physiology shows that our brain clock can be shifted by light exposure, potentially to align it with night shift patterns. It highlights that a 'one size fits all' approach to managing sleep disruption in shift workers may not be appropriate. A personalized approach, with light-dark exposure scheduled and taking into account whether someone is a 'morning' or 'evening' person, could reduce shift workers' risk of health problems. (2018-03-27)

Researchers correlate rheumatoid arthritis and giant cell arteritis with solar cycles
A rare collaboration of physicists and medical researchers finds a correlation between rheumatoid arthritis and giant cell arteritis and solar cycles. (2015-06-15)

Researchers develop dietary formula that maintains youthful function into old age
Researchers develop dietary formula that maintains youthful function into old age. (2010-02-11)

Texting at night affects teens' sleep, academic performance
The study, published in the Journal of Child Neurology, is the first of its kind to link nighttime instant messaging habits of American teenagers to sleep health and school performance. (2016-01-26)

Our muscles measure the time of day
Biological clocks are ticking everywhere throughout our body, and a 'master clock' in the brain synchronizes all the subsidiary ones in various organs. An international team of researchers led by the University of Geneva, Switzerland, and supported by the SNSF, has found that such a circadian clock is at work in our muscles. Their research shows that perturbations of this machinery might be important for type 2 diabetes development. (2017-10-02)

Late sleep-wake time preference linked to depression in individuals with diabetes
People with type 2 diabetes who are 'night owls' and prefer the evening for activity report having more symptoms of depression than those who are early to bed and early to rise, regardless of the quality of their sleep, a new study finds. Study results are being presented Saturday at the Endocrine Society's 99th annual meeting in Orlando, Fla. (2017-04-01)

Slumber aids could improve intensive care outcomes
Eye masks and earplugs could help hospital patients get a better night's sleep. Researchers writing in BioMed Central's open-access journal Critical Care investigated their effect on sleep quality in a simulated intensive care environment. (2010-04-14)

Research finds antioxidant therapies do not interfere with radiation treatment
Researchers at the Cancer Treatment Centers of America found that antioxidant therapies such as green tea extract, melatonin, high-potency multivitamins, vitamin C and vitamin E do not interfere with radiation treatment. (2006-11-09)

Study links late sleep timing to poorer diet quality and lower physical activity
A new study suggests that among healthy adults with a habitual sleep duration of at least 6.5 hours, late sleep timing was associated with higher fast food consumption and lower vegetable intake, particularly among men, as well as lower physical activity. (2016-06-08)

Teen night owls likely to perform worse academically, emotionally
Teenagers who go to bed late during the school year are more prone to academic and emotional difficulties in the long run, compared to their earlier-to-bed counterparts, according to a new study from the University of California, Berkeley. (2013-11-11)

Montreal researchers shed new light on cancer risks associated with night work
Night work can increase cancer risk in men, according to a new study published in the American Journal of Epidemiology by a research team from Centre INRS -- Institut Armand-Frappier and Centre de recherche du Centre hospitalier de l'Université de Montréal. The study is one of the first in the world to provide evidence among men of a possible association between night work and the risk of prostate, colon, lung, bladder, rectal, and pancreatic cancer and non-Hodgkin's lymphoma. (2012-10-15)

Biological clock more influenced by temperature than light
Getting over jet lag may be as simple as changing the temperature --your brain temperature, that is. That's a theory proposed by Erik Herzog, Ph.D. assistant professor of biology in Arts & Sciences at Washington University in St. Louis. Herzog has found that the biological clocks of rats and mice respond directly to temperature changes. (2003-07-14)

Study shines light on night-time alertness
The circadian system is not the only pathway involved in determining alertness at night. Research described in the open access journal BMC Neuroscience showed that red light, which does not stimulate the circadian system, is just as effective at increasing night-time alertness as blue light, which does. (2009-08-26)

Economic recovery is stronger in states where people are more optimistic, says UM study
Economic recessions are weaker, expansions are stronger, and economic recovery is faster in US states where people are more optimistic says a new study from the University of Miami School of Business Administration. Further, the effects are stronger in states where people are older, less educated and less socially connected. (2011-05-25)

USC researchers present diabetes findings at American Diabetes Association Scientific Sessions
Keck School of Medicine of the University of Southern California (USC) researchers will present findings at the American Diabetes Association scientific sessions June 5-9, 2009. Research includes helping diabetes patients avoid post-exercise hypoglycemia, as well as the role of pancreatic beta cells in the progression of diabetes. (2009-06-04)

Keeping the body in sync -- the stability of cellular clocks
A study in Switzerland uses the tools of physics to show how our circadian clocks manage to keep accurate time in the noisy cellular environment. (2007-03-13)

Use of medication to treat pediatric insomnia is common, study finds
Although guidelines do not exist for the use of medication to treat pediatric sleep disorders, about 75 percent of pediatricians surveyed had recommended some type of medication for that purpose within the previous six months. Pediatric sleep disturbances are among the most common and challenging complaints, and a set of clinical experience-based guidelines needs to be developed, according to a study in the May Pediatrics. (2003-05-05)

Amber-tinted glasses may provide relief for insomnia
Researchers from Columbia University Medical Center tested a method to reduce the adverse effects of evening ambient light exposure, while still allowing use of blue light-emitting devices. (2017-12-15)

Study links night exposure to blue light with breast and prostate cancer
A study published in Environmental Health Perspectives reports a link between exposure to blue light at night and higher risk of developing breast and prostate cancer. Blue light is a range of the visible light spectrum emitted by most white LEDs and many tablet and phone screens. (2018-04-25)

Poor sleep more dangerous for women
Researchers at Duke University Medical Center say they may have figured out why poor sleep does more harm to cardiovascular health in women than in men. Their study, appearing online in the journal Brain, Behavior and Immunity, found that poor sleep is associated with greater psychological distress and higher levels of biomarkers associated with elevated risk of heart disease and type 2 diabetes. They also found that these associations are significantly stronger in women than in men. (2008-03-10)

Human health, astronomy, and environmental concerns merge at Dark-Sky meeting
Physicians, engineers, national park staff, astronomers, government officials, and many others will gather at the 16th Annual International Dark-Sky Association Meeting in Tucson, Ariz., March 10-13, to discuss their shared interest in the night-time environment and its affect on human activity. (2004-03-01)

Under a cloud -- darkness linked to 'brain drain' in depressed people
A lack of sunlight is associated with reduced cognitive function among depressed people. Researchers writing in BioMed Central's open-access journal Environmental Health used weather data from NASA satellites to measure sunlight exposure across the United States and linked this information to the prevalence of cognitive impairment in depressed people. (2009-07-27)

Mood, cognition and sleep patterns improve in Alzheimer's patients after cataract surgery
Researchers at Tenon Hospital, Paris, France, found that patients with mild Alzheimer's disease whose vision improved after cataract surgery also showed improvement in cognitive ability, mood, sleep patterns and other behaviors. Lead researcher Brigitte Girard, M.D., will discuss her team's results today at the American Academy of Ophthalmology's 2011 Annual Meeting. (2011-10-25)

FASEB announces the 2011 Summer Research Conference series: Registration is now open
Since 1982, the FASEB SRCs have offered a continuing series of interdisciplinary exchanges that are recognized as a valuable complement to the highly successful society meetings. Divided into small groups, scientists from around the world meet intimately and without distractions to explore new approaches to those research areas undergoing rapid scientific changes. FASEB has announced 37 SRCs planned for the summer of 2011. (2011-02-16)

Study: Homeschooled kids sleep more than others
In the first study of its kind published in the journal Behavioral Sleep Medicine, researchers have determined that teens who are homeschooled benefit from healthier sleep habits than those who go to most private and public schools. The findings provide additional evidence of teens' altered biological clocks and support an argument for starting traditional high school later in the morning. (2016-03-02)

Does night work put women's health at risk?
The results of a study carried out by the researchers of the Inserm unit 1018 and published in the International Journal of Cancer show that the risk of developing breast cancer is higher among women who have worked at night. The study, carried out in France and named the CECILE study, compared the careers of 1,200 women who had developed breast cancer between 2005 and 2008 with the careers of 1,300 other women. (2012-06-19)

Delayed meal times reset body clocks
The human body runs according to a roughly 24-hour cycle, controlled by a 'master' clock in the brain and peripheral clocks in other parts of the body that are synchronized according to external cues, including light. Now, researchers reporting in Current Biology on June 1 have found that at least one of those clocks can also be reset based on what time a person eats breakfast, lunch, and dinner. (2017-06-01)

New guideline provides clinical recommendations for specific insomnia drugs
A new clinical practice guideline is the first from the American Academy of Sleep Medicine to provide comprehensive, evidence-based analyses of individual agents commonly used in the treatment of chronic insomnia disorder. (2017-02-14)

Bright light after night shift may enhance alertness and cognitive performance
A new study suggests that bright light at the end of a night shift may have potential as a countermeasure to improve driving performance, particularly for low light work environments and commutes that occur before dawn. (2015-06-11)

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