Mesothelioma Current Events

Mesothelioma Current Events, Mesothelioma News Articles.
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Overlooked lymph nodes in rib cage have prognostic power for mesothelioma patients
For the first time, researchers from the Perelman School of Medicine at the University of Pennsylvania have shown the predictive power of a group of overlooked lymph nodes that could serve as a better tool to stage and ultimately treat patients with malignant pleural mesothelioma. (2013-10-28)

Aspirin may delay growth of asbestos-related cancer
A University of Hawai'i Cancer Center study finds aspirin may help mesothelioma patients. (2015-07-06)

Early promise of blood marker to detect mesothelioma
Preliminary results of a study in this week's issue of The Lancet suggest that a blood test could be used in the future to identify people with mesothelioma-the usually deadly malignant tumor of mesothelial tissue surrounding the lungs, often caused by exposure to asbestos. (2003-11-13)

Researchers find potential new target to treat malignant pleural mesothelioma
In the September issue of the International Association for the Study of Lung Cancer's journal, the Journal of Thoracic Oncology, researchers conclude that Ephrin B2 seems to play an important role in malignant pleural mesothelioma cell lines and tumors. (2013-07-25)

New technique can help diagnose mesothelioma
A new technique may help clinicians hone in on a diagnosis in patients presenting with a pleural effusion of unknown cause. (2009-08-24)

Asbestos disease projections too low
Current predictions of the future incidence of asbestos-related disease have been substantially underestimated, according to new modelling to be presented in Melbourne today by an epidemiologist from the Australian National University. (2007-04-02)

UH Cancer Center receives $3.58 million gift for mesothelioma research
The UH Cancer Center has received a $3.58 million gift from an anonymous donor to support the mesothelioma research of Dr. Michele Carbone, director of the UH Cancer Center. Carbone and colleagues, who include Drs. Haining Yang and Giovanni Gaudino, have made a series of recent scientific breakthroughs that will lead to new ways to prevent and treat the disease. (2011-06-23)

Exposure to contaminated poliovirus vaccine not likely linked to rare cancer
The poliovirus vaccine used in mass immunization programs in the late 1950s and early 1960s was contaminated with the monkey virus SV40, which has been detected in some human tumors, particularly pleural mesothelioma. However, the rise in incidence of pleural mesothelioma between 1975 and 1997 is not likely the result of immunization with the SV40-contaminated vaccine, according to an analysis in the January 1 issue of the Journal of the National Cancer Institute. (2002-12-31)

International conference focuses on mesothelioma
The University of Chicago's Pritzker School of Medicine will host the eighth conference of the International Mesothelioma Interest Group (IMIG) from Thursday, October 19, through Sunday, October 22, 2006, at the Sheraton Chicago Hotel and Towers, 301 E. North Water Street in Chicago. (2006-10-18)

Two drugs used in combination prove to be effective against most aggressive asbestos cancer in mice
Currently, there are few effective treatments for malignant mesothelioma, although it has been decades since it was found that the major risk factor is exposure to asbestos. The drugs identified by CNIO researchers are being tested on other types of cancer, which can speed up clinical trials for mesothelioma. The authors identified molecular markers that could be used to determine which patients could benefit most from this new therapy, provided that it is approved. (2020-01-08)

New drug hope for mesothelioma
A new drug is showing promise as a treatment for mesothelioma -- one of the most lethal cancers of all. The drug, known as HRX9, works by preventing the cancer cells from avoiding apoptosis -- the natural process by which unhealthy and damaged cells close themselves down and die. (2016-03-14)

Exposure to volcanic mineral associated with increased mesothelioma incidence in Turkey
High exposure to a fibrous volcanic mineral called erionite was associated with a high incidence of a type of cancer called mesothelioma, according to a study in the March 15 issue of the Journal of the National Cancer Institute. (2006-03-14)

Malignant mesothelioma - therapeutic options and role of SV40
This meeting will focus on the recent studies demonstrating that simian virus 40 (SV40) is associated with a significant portion of human mesotheliomas as well as brain and bone tumors. (2001-04-09)

Study suggests improvements in how mesothelioma is staged
A new study suggests that significant improvements could be made in the scoring system physicians use to estimate the stage (severity) of mesothelioma, an aggressive and deadly cancer. (2016-02-02)

Possible vaccine for mesothelioma proven safe
Researchers have demonstrated the safety of a potential vaccine against mesothelioma, a rare cancer associated primarily with asbestos exposure. The vaccine, which infuses uses a patient's own dendritic cells with antigen from the patient's tumor, was able to induce a T cell response against mesothelioma tumors. (2010-03-04)

University of Hawaii cancer researchers discover gene defect responsible for cancer syndrome
University of Hawai'i Cancer Center researchers have discovered germline BAP1 mutations are associated with a novel cancer syndrome characterized by malignant mesothelioma, uveal melanoma, cutaneous melanoma and atypical melanocytic tumors. Germline mutations are hereditary gene defects that are present in every cell. (2012-09-05)

UH Cancer Center and Jabsom researchers receive $3 million US Department Of Defense Awards
University of Hawai'i Cancer Center and John A. Burns School of Medicine researchers were awarded three out of only 45 United States Department of Defense grants for cancer research and career development. The awards to the University of Hawai'i are for malignant mesothelioma research and total more than $3 million. (2016-03-30)

Mesothelioma drug slows disease progression in patients with an inactive NF2 gene
Preliminary findings from the first trial of a new drug for patients with mesothelioma show that it has some success in preventing the spread of the deadly disease in patients lacking an active tumour suppressor gene called NF2. The study is presented at the 24th EORTC-NCI-AACR Symposium on Molecular Targets and Cancer Therapeutics in Dublin, Ireland. (2012-11-08)

Mesothelioma surgery improves quality of life, study finds
Many mesothelioma patients avoid surgery for fear it will degrade their quality of life. But a study has found just the opposite: Patients who underwent an operation called pleurectomy and decortication (PD) generally reported their quality of life improved after surgery. (2016-06-08)

The test that reveals cancer sooner
MorNuCo Laboratories' clinical trial, recently published in Clinical Proteomics, demonstrated the ability of a serum test to detect the presence of mesothelioma 4-10 years in advance of clinical symptoms. The ONCOblot® Test detects ENOX2 proteins present in serum, and in this trial, ENOX2 proteins that are specific to mesothelioma. This is an exciting step forward in the continued development of tools for early cancer detection. (2016-02-04)

New study finds cancer-causing mineral in US road gravel
Vehicles traveling along gravel roads in Dunn County, North Dakota stir up clouds of dust containing high levels of the mineral erionite. Those who breathe in the air every day are at an increased risk of developing mesothelioma, new research shows. Erionite shares similar physical similarities with asbestos and when airborne, its fibers can lodge in people's lungs. Over time, the embedded fibers can lead to mesothelioma, a lung cancer most often associated with asbestos. (2011-07-25)

High levels of blood-based protein specific to mesothelioma
Researchers at NYU School of Medicine have discovered the protein product of a little-known gene may one day prove useful in identifying and monitoring the development of mesothelioma in early stages, when aggressive treatment can have an impact on the progression of disease and patient prognosis. (2012-10-10)

Idiopathic pulmonary fibrosis cases linked with asbestos exposure
A proportion of idiopathic pulmonary fibrosis (IPF) cases may be linked with asbestos exposure, according to the results of a new study. If confirmed, the findings would mean that current treatment strategies need to be altered as people with a history of asbestos exposure are not currently able to access new treatments for IPF. (2014-09-09)

Landmark asbestos study published in The Lancet Public Health
A landmark study from The Australian National University into the health impacts of living in a house with loose-fill asbestos insulation has been published in the international journal The Lancet Public Health. (2017-11-01)

Rare genetic cause of peritoneal mesothelioma points to targeted therapy
BWH investigators have uncovered a new genetic cause of mesothelioma: a genetic rearrangement in the ALK gene, observed in three patients with peritoneal mesothelioma. Unlike previously known causes, this new discovery points to a potential therapeutic approach for those few patients whose tumors harbor the mutation. The team's findings are published in JAMA Oncology. (2017-09-14)

Tiny golden bullets could help tackle asbestos-related cancers
Gold nanotubes - tiny hollow cylinders one thousandth the width of a human hair - could be used to treat mesothelioma, a type of cancer caused by exposure to asbestos, according to a team of researchers at the Universities of Cambridge and Leeds. (2020-10-26)

Radiotherapy doubles survival for patients with mesothelioma
Mesothelioma patients are twice as likely to survive for two years or longer, if they are treated with a high dose of radiation to the affected side of the trunk, according to research presented at the ESTRO 38 conference. (2019-04-28)

Study pinpoints malignant mesothelioma patients likely to benefit from drug pemetrexed
Previous studies have hypothesized that low levels of the enzyme thymidylate synthase (TS) likely mark patients who will benefit from the drug pemetrexed - but results have been inconclusive at best and at times contradictory. A University of Colorado Cancer Center study recently published in the Journal of Thoracic Oncology provides an explanation why: Only in combination with high levels of a second enzyme, FPGS, does low TS predict response to pemetrexed in patients with malignant pleural mesothelioma. (2012-08-29)

Study examines association of asbestos exposure, mesothelioma in Eastern China
A new research letter published online by JAMA Oncology looks at asbestos exposure and malignant mesothelioma in Eastern China. (2016-12-01)

Renal cancer drug temsirolimus shows promise against mesothelioma
A drug commonly used to treat kidney cancer may increase the effectiveness of chemotherapy for mesothelioma, according to a study published in the May issue of the Journal of Thoracic Oncology. (2011-05-01)

Novel blood-based protein signature determined for rare, aggressive lung cancer
Researchers have discovered a panel of 13 blood proteins that may be effective biomarkers to detect malignant mesothelioma, according to a study published Oct. 3 in the open-access journal PLOS ONE by Rachel Ostroff from the company SomaLogic, which developed the new test, and colleagues at other institutions. (2012-10-03)

Elevated blood levels of a protein are linked to asbestos-induced cancers
Researchers at New York University School of Medicine and Wayne State University have found a molecule that reveals the early stages of pleural mesothelioma, a chest cancer caused by asbestos. The finding opens the way to a blood test for the disease, according to a new study published in the Oct. 13 issue of The New England Journal of Medicine. (2005-10-12)

Mesothelioma in southern Nevada likely result of asbestos in environment
Malignant mesothelioma has been found at higher than expected levels in women and in individuals younger than 55 years old in the southern Nevada counties of Clark and Nye, likewise in the same region carcinogenic mineral fibers including actinolite asbestos, erionite, winchite, magnesioriebeckite and richterite were discovered. These data suggest that these elevated numbers of malignant mesothelioma cases are linked to environmental exposure of carcinogenic mineral fibers. (2015-02-10)

Morphote Inc. announces initiation of MORAb-009 Phase II study in first-line treatment of mesothelioma
Morphotek Inc., a subsidiary of Eisai Corporation of North America, today announced that it has commenced a multicentered Phase II study of its MORAb-009 monoclonal antibody in mesothelioma. (2009-03-02)

Secretome of pleural effusions associated with non-small cell lung cancer (NSCLC) and malignant...
Cryopreserved cell-free PE fluid from 101 NSCLC patients, 8 mesothelioma and 13 with benign PE was assayed for a panel of 40 cytokines/chemokines using the Luminex system. Comparing NSCLC PE and published plasma levels of CAR-T recipients, both were dominated by sIL-6R and IL-6 but NSCLC PE had more VEGF, FGF2 and TNF, and less IL-2, IL-4, IL-13, IL-15, MIP1 and IFN. (2019-11-22)

New drug boost for asbestos-related lung cancer sufferers
Clinical trials of a new anticancer drug combination carried out by researchers at Newcastle University show that it has potential to almost double the life expectancy of sufferers of Mesothelioma - a form of lung cancer which affects around 1,700 people in the UK every year - according to a report published in the Journal of Clinical Oncology. (2002-08-13)

Naturally occurring asbestos linked to lung cancer
Everyday exposure to naturally occurring asbestos increases the risk of developing malignant mesothelioma, according to a study by UC Davis researchers. The study - the largest to examine the question - will be published this fall in the American Journal of Respiratory and Critical Care Medicine. (2005-07-12)

Asbestos cancer breakthrough
Researchers at the Pacific Northwest Research Institute (PNRI) have reported the development of a blood test for mesothelioma, a highly aggressive lung cancer caused by asbestos exposure. (2003-11-13)

Exposure to North Dakota road material may increase risk of lung cancer
New data shows that people exposed to the mineral erionite found in the gravel of road materials in North Dakota may be at significantly increased risk of developing mesothelioma, a type of lung cancer most often associated with asbestos exposure, according to research presented at the 2010 Chicago Multidisciplinary Symposium in Thoracic Oncology. (2010-12-09)

Nanotubes could pose health risk to production line staff, study suggests
Tiny fibers used to strengthen everyday products such as bicycle frames and hockey sticks could pose health hazards to those involved in their manufacture. Certain types of carbon nanotubes -- cylindrical molecules about one-thousandth of the width of a human hair -- could cause cancer in the lining of the lung, University of Edinburgh researchers have found. (2011-06-14)

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