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Microtubule Current Events

Microtubule Current Events, Microtubule News Articles.
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HKUST researchers reveal new insights into the control of cellular scaffold
HKUST researchers made a breakthrough in understanding how the organization of microtubule cytoskeleton is controlled, revealing an aspect of γTuRC's regulation and demonstrated a previously unknown function of PolD1, a conserved protein that is widely recognized for its role in DNA replication and repair. (2017-11-29)
One-dimensional diffusion accelerates molecular motors
Max Planck researchers discover how special motor proteins identify microtubule ends. (2006-05-12)
Cracks in the cellular transport system can be key to a new generation of cancer therapies
Researchers from Warwick Medical School have discovered a critical point of failure in the microscopic transport system that operates inside every cell in the human body. (2014-01-27)
How your cells build tiny 'train tracks' could shed light on human disease
Researchers from the University of Warwick have discovered how cells in the human body build their own 'railway networks', throwing light on how diseases such as bowel cancer work. (2016-02-11)
Researchers identify protein essential for healthy gut cell development
Scientists have uncovered key processes in the healthy development of cells which line the human gut, furthering their understanding about the development of cancer. (2017-02-07)
A molecular mechanism involved in cellular proliferation characterized
Researchers from Guillermo Montoya's team at the Spanish National Cancer Research Centre, in collaboration with Isabelle Vernos' Group from the CRG, have uncovered the molecular interaction between TACC3 and chTOG, key proteins in forming the internal cellular framework that enables and sustains cell division. (2014-09-29)
Microtubule protein interactions visualized en masse
Previously unknown interactions between different microtubule- associated proteins (MAPs) are identified via a new technique, termed visual immunoprecipitation. (2007-01-15)
Revealing the inner workings of a molecular motor
In research published in the Journal of Cell Biology, scientists from the RIKEN Brain Science Institute in Japan have made important steps toward understanding how dynein -- a 'molecular motor' -- walks along tube-like structures in the cell to move cellular cargo from the outer structures toward the cell body of neurons. (2015-01-12)
Researchers unlock secrets of cell division, define role for protein elevated in cancer
Researchers at Princeton University have successfully recreated a key process involved in cell division in a test tube, uncovering the vital role played by a protein that is elevated in over 25% of all cancers. (2020-01-14)
Cell biology -- new insights into the life of microtubules
Every second, around 25 million cell divisions take place in our bodies. (2012-07-02)
Atomic view of microtubules
Berkeley Lab researchers produced an atomic view of microtubules that enabled them to identify the crucial role played by a family of end-binding proteins in regulating microtubule dynamic instability, the physical property that enables microtubules to play a crucial role in cell division. (2015-08-04)
For cells, internal stress leads to unique shapes
Caltech researchers discover that a cell's unique shape results from an internal tug-of-war: the cell needs to maintain structural integrity while also dynamically responding to the pushes and pulls of mechanical stress. (2014-04-16)
Study uncovers how cells organize the growth of their structural filaments
Researchers have described how two proteins work together to guide the assembly of important structural elements known as microtubules within the cell. (2016-10-19)
Life's smallest motor, cargo carrier of the cells, moves like a seesaw
Life's smallest motor, a protein that shuttles cargo within cells and helps cells divide, does so by rocking up and down like a seesaw according to new high-resolution snapshots of a protein called kinesin. (2010-02-17)
How does Rho-associated protein kinase modulate neurite extension?
How does Rho-associated protein kinase modulate neurite extension? (2013-12-26)
Study: Tau does not stabilize microtubules, challenges approach to treating Alzheimer's
Though it is widely believed that tau protein stabilizes microtubules in neurons of the brain, new research suggests just the opposite: tau lengthens microtubules and keeps them dynamic. (2018-06-28)
A new molecular player involved in T cell activation
Scientists at Tokyo Institute of Technology have imaged live T cells to reveal the role of CLIP-170 in T-cell activation, a critical process in the immune response. (2018-12-06)
How cells keep in shape
Researchers at the European Molecular Biology Laboratory and the Institute for Atomic and Molecular Physics, the Netherlands, have now decoded a molecular mechanism that plays an important role in the development of a cell's shape. (2007-12-02)
How to build a better railway -- in (almost) every cell in your body
New work from the University of Warwick shows how a microscopic 'railway' system in our cells can optimise its structure to better suit bodies' needs. (2018-03-12)
Paper offers insights into network that plays crucial role in cell function and disease
A new research paper from the labs of University of Notre Dame researchers Holly Goodson and Mark Alber helps resolve an ongoing debate about the assembly of a subcellular network that plays a critical role in cell function and disease. (2014-02-05)
Experiments show hypothesis of microtubule steering accurate
Tiny protein motors in cells can steer microtubules in the right direction through branching nerve cell structures, according to Penn State researchers who used laboratory experiments to test a model of how these cellular information highways stay organized in living cells. (2014-01-23)
The ins and outs of building the sperm tail
In the latest issue of the journal Developmental Cell, scientists from the Instituto Gulbenkian de Ciência, in Portugal, have dissected how sperm cells of the fruit fly build their flagella. (2012-08-13)
Microtubules act as cellular 'rheostat' to control insulin secretion
Microtubules -- cellular 'highways' that deliver cargo to the cell membrane for secretion -- have a surprising role in pancreatic beta cells. (2015-12-04)
New regulator of neuron formation identified
The protein NEK7 regulates neuron formation, as it is required for dendrite growth and branching, as well as the formation and shaping of dendritic spines. (2018-06-27)
University of East Anglia scientists make major advances important for cancer research
Scientists at the University of East Anglia have made a major advancement in understanding tissue development that has important implications for cancer. (2013-06-26)
Attention! End of traffic jam!
Interdisciplinary research between biology and physics aims to understand the cell and how it organizes internally. (2011-11-07)
How neurons get their branching shapes
Researchers at the RIKEN Brain Science Institute in Japan have discovered a factor helps give different neurons their distinct shapes. (2015-08-31)
Roadworks on the motorways of the cell
Microtubules constantly grow and shrink, but during cellular transport they need to be kept stable. (2006-12-28)
Fruit fly neuron can reprogram itself after injury
Studies with fruit flies have shown that the specialized nerve cells called neurons can rebuild themselves after injury. (2009-12-06)
A peptide to protect brain function
Prof. Illana Gozes of Tel Aviv University has developed a new peptide, called NAP or Davunetide, that has the capacity to both protect and restore critical cell functions in the brain. (2013-06-13)
Key mechanism in genetic inheritance during cell division identified
A key mechanism in the passing of genetic material from a parent cell to daughter cells appears to have been identified by a team of Berkeley researchers. (2005-02-01)
Visualizing 'unfurling' microtubule growth
Living cells depend absolutely on microtubules that form a scaffolding for moving materials inside the cell. (2018-11-13)
A patent study on the great new hope emerging from marine derived anticancer drugs
Anticancer agents targeting microtubule from marine sources hold great potential in the field of cancer therapeutics and are gradually advancing in the clinical setup. (2017-06-21)
Tug of war in the cells
Logistics is a key part of life. Nutrition, tools and information constantly have to be transported from one place to another in cells. (2008-03-19)
Unsung hero: Berkeley researchers produce high-res model of Ndc80 in action
Berkeley Lab scientists used cryo-electron microscopy and three-dimensional image reconstruction to create a subnanometer resolution image of Ndc80, a protein complex that helps prevent chromosomal distribution mistakes during mitosis that can lead to birth defects, cancer and other disorders. (2010-10-13)
Constant overlap
Scientists at the European Molecular Biology Laboratory in Heidelberg, Germany, have uncovered the molecular mechanism that determines the size of anti-parallel microtubule overlaps in the spindle. (2010-08-06)
Machinery used in basic cell division does double duty as builder of neurons
Researchers at the San Diego branch of the Ludwig Institute for Cancer Research at University of California San Diego have identified an entirely new mechanism underlying the development and structure of the nervous system during embryogenesis. (2019-02-28)
Molecular motors and brakes work together in cells
Researchers at the University of Pennsylvania School of Medicine have discovered that microtubules -- components responsible for shape, movement, and replication within cells -- use proteins that act as molecular motors and brakes to organize into their correct structure. (2007-01-30)
Scientists make stunning inner space observations
High-powered microscopes reveal workings of the cell -- results could impact treatment of Down syndrome, lissencephaly (a brain formation disorder) or cancer. (2012-05-01)
Bionanomachines -- proteins as resistance fighters
Friction limits the speed and efficiency of macroscopic engines. Is this also true for nanomachines? (2009-08-14)
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