Muscular Dystrophy Current Events

Muscular Dystrophy Current Events, Muscular Dystrophy News Articles.
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Hope for muscular dystrophy patients: Harnessing gene helps repair muscle damage
Researchers have successfully improved the ability of muscle to repair itself -- by artificially increasing levels of the BMI1 gene in the muscle-specific stem cells of mice with muscular dystrophy. (2015-01-15)

Pioneering research into Duchenne muscular dystrophy secures commercial funding
Royal Holloway University is giving money generated by its research into Duchenne muscular dystrophy to the Muscular Dystrophy Campaign. Families affected by the condition are also visiting laboratories on campus to find out from the scientists about new drug developments and see the work being carried out. (2013-03-27)

Limb-girdle muscular dystrophy subtypes in the population of Northeast China
This release focuses on limb-girdle muscular dystrophy subtypes in the population of Northeast China. (2013-08-11)

Muscular dystrophy: Repair the muscles, not the genetic defect
A potential way to treat muscular dystrophy directly targets muscle repair instead of the underlying genetic defect that usually leads to the disease. (2014-09-14)

Risk factors for sudden death for adult muscular dystrophy identified
The largest assessment of people with adult muscular dystrophy has identified risk factors that can lead to sudden death for individuals with the most common form of this disease. Results of multi-center study, led by Indiana University School of Medicine researchers, are published in June 19 New England Journal of Medicine. (2008-06-18)

Researchers discover molecular basis of a form of muscular dystrophy
A team of French and German researchers report in the May 2008 print issue of the FASEB Journal that people with limb-girdle muscular dystrophy are missing a protein called c-FLIP, which the body uses to prevent the loss of muscle tissue. By targeting the cellular and molecular mechanisms responsible for creating this protein, scientists could develop new drugs to stop muscle wasting from limb-girdle muscular dystrophy and other conditions. (2008-04-30)

Early cardiac screening necessary for muscular dystrophy patients
Early diagnosis and treatment of heart disease may lead to longer life in Duchenne and Becker muscular dystrophy patients, say experts at Baylor College of Medicine (BCM) and Texas Children's Hospital in Houston in a report that appeared online in the journal Circulation. (2005-10-28)

UI Study Reveals Important Information About Molecular Defect In Limb Girdle Muscular Dystrophy
For the first time ever, University of Iowa researchers have confirmed how a protein complex, when defective, causes limb girdle muscular dystrophy. (1999-03-04)

New gene linked to muscular dystrophy
Muscular dystrophy, a group of inherited diseases characterized by progressive skeletal muscle weakness, can be caused by mutations in any one of a number of genes. Another gene can now be added to this list, as researchers have now identified mutations in a gene not previously linked to muscular dystrophy as causative of a form of the disease in five nonconsanguineous Japanese patients. (2009-08-10)

New therapeutic insight into duchenne muscular dystrophy
In the April 1 issue of Genes & Development, Dr. Bruce Spiegelman (Dana Farber Cancer Institute) and colleagues identify a key genetic component of and possible therapeutic target for Duchenne muscular dystrophy. (2007-03-31)

$7 million grant designates Nationwide Children's as Wellstone Center
A $7 million grant from the National Institutes of Health will help researchers at Nationwide Children's Hospital translate new scientific findings and technological developments into novel treatments for the muscular dystrophies. The grant designates Nationwide Children's Hospital as a Paul D. Wellstone Muscular Dystrophy Cooperative Research Center, one of three national award recipients in 2010. (2010-08-26)

Toxic molecule may cause most common type of muscular dystrophy
Doctors at the University of Virginia Health System have shown for the first time that getting rid of poisonous RNA (ribonucleic acid) in muscle cells can reverse myotonic dystrophy, the most common type of muscular dystrophy in adults. (2006-08-24)

New knowledge about serious muscle disease
Recent research from University of Copenhagen sheds light on previously unknown facts about muscular dystrophy at molecular level. The breakthrough is hoped to improve future diagnosis and treatment of the disease. Researchers have developed a method that will make it easier to map the proteins that have an important kind of sugar monomer, mannose, attached. This is an important finding, as mannose deficiency can lead to diseases such as muscular dystrophy. (2013-10-31)

New research increases understanding of Duchenne muscular dystrophy
A new paper, co-written by faculty at Binghamton University, State University of New York, increases the understanding of Duchenne muscular dystrophy (DMD) -- one of the most common lethal genetic disorders -- and points to potential therapeutic approaches. (2016-10-13)

McCaw/Muscular Dystrophy Association fund supports UW recruitment of internationally noted gene therapy researcher
Dr. Jeffrey S. Chamberlain, an international leader in efforts to find gene therapies for muscular dystrophy, has been recruited to the faculty of the University of Washington (UW) School of Medicine. A gift of $775,000 from the McCaw/Muscular Dystrophy Association Fund will help support his research. (2001-01-16)

New muscular dystrophy drug target identified
Scientists at the University of Liverpool have discovered that muscle cells affected by muscular dystrophy contain high levels of an enzyme that impairs muscle repair. This finding provides a new target for potential drug treatments for the disease, which currently has no cure. (2016-06-01)

Researchers discover chemical that may protect hearts of muscular dystrophy patients
Researchers at the University of Minnesota Medical School have discovered a chemical that may, over the long term, protect the hearts of Duchenne muscular dystrophy patients -- a fatal and most common form of muscular dystrophy in children. (2010-03-15)

Genetic test could aid quest to reveal causes of rare diseases
The causes of rare diseases could be uncovered using an approach created to identify genetic mutations that trigger a muscle-wasting condition, a study suggests. (2019-12-17)

New therapy substitutes missing protein in those with muscular dystrophy
Researchers at the University of Minnesota Medical School have discovered a new therapy that shows potential to treat people with Duchenne muscular dystrophy, a fatal disease and the most common form of muscular dystrophy in children. (2009-05-26)

Treatment in mice proves effective against Duchenne muscular dystrophy
Mice carrying the same gene deficiencies as humans with Duchenne muscular dystrophy experienced dramatic improvements in both their physical condition and life span following an experimental treatment by researchers at the University of Illinois. (2001-03-18)

Researchers identify new function for protein missing in Duchenne muscular dystrophy
Researchers at the University of Minnesota and National Institutes of Health have identified a new function for the protein missing in people with the most common and ultimately lethal form of childhood muscular dystrophy. (2009-08-03)

MDA, Walgreens collaborate to provide flu shots at more than 8,000 locations
Muscular Dystrophy Association has partnered with Walgreens pharmacies to provide flu shots at more than 8,000 locations nationwide for people with neuromuscular diseases. Families living with neuromuscular diseases should visit MDA's Flu Season Resource Center or call 800-572-1717 to get flu shot vouchers. The vouchers can be redeemed at Walgreens or Duane Reade pharmacies; or Walgreens Take Care Clinics. (2011-09-13)

Decoding sugar molecules offers new key for combating muscular dystrophy
A group of Japanese scientists have succeeded in decoding a sugar molecule and clarifying a mechanism linked to muscular dystrophy. Their discovery has potential implications for muscular dystrophy treatment. The results of their research were published in the journal Cell Reports on Feb. 25, 2016. (2016-03-29)

Gene, stem cell therapy only needs to be 50 percent effective to create a healthy heart
According to a new study, recently published in Circulation Research, a journal of the American Heart Association, University of Missouri-Columbia researchers have demonstrated that a muscular dystrophy patient should be able to maintain a normal lifestyle if only 50 percent of the cells of the heart are healthy. (2007-10-31)

White Americans living longer with muscular dystrophy than African-Americans
A new study shows that white men and boys are living longer with muscular dystrophy due to technological advances in recent years, but that the lives of African-American men and boys with muscular dystrophy have not been extended at the same rate. The research will be published in the Sept. 14, 2010, issue of Neurology, the medical journal of the American Academy of Neurology. (2010-09-13)

Barrow Neurological Institute neuroimmunology fellow receives $135,000 fellowship award
Ruolan Liu, MD, PhD, a post-doctoral fellow at Barrow Neurological Institute in Phoenix, received a three-year career development fellowship of $135,000 from the Muscular Dystrophy Association. This prestigious award will fund Dr. Liu's investigation of natural-killer-T (NKT) cell treatment for Myasthenia Gravis (MG) and other autoimmune diseases. (2006-02-06)

New treatment for common form of muscular dystrophy shows promise in cells, animals
Researchers have designed a potential new treatment for one of the most common forms of muscular dystrophy, according to a new study published today in the Proceedings of the National Academy of Sciences. Toshifumi Yokota, professor of medical genetics at the University of Alberta, led a team from Canada and the U.S. to create and test synthetic DNA-like molecules that interfere with the production of a toxic protein that destroys the muscles of people who have facioscapulohumeral muscular dystrophy (FSHD). (2020-06-29)

Scientist of the year award for Duchenne Muscular Dystrophy research
The School of Biological Sciences at Royal Holloway, University of London has been recognized with a national award for its world-class research in the development of novel therapies for rare diseases, such as Duchenne Muscular Dystrophy. (2014-10-29)

U of MN researchers develop first reliable diagnostic test for myotonic muscular dystrophy type 2
Researchers at the University of Minnesota Medical School's Muscular Dystrophy Center have developed the first reliable diagnostic test for myotonic muscular dystrophy type 2 (DM2), leading to the accurate determination of the disease's clinical and molecular features. (2003-02-25)

Weekly steroids strengthen and repair muscles
In a surprising finding, weekly doses of glucocorticoid steroids, such as prednisone, help speed recovery in muscle injuries, reports a new study. The weekly steroids also repaired muscles damaged by muscular dystrophy. When given daily over long periods, prednisone can cause muscle wasting. But the once weekly doses of the steroid increased proteins that stimulate muscle repair. The studies were conducted in mice, with broad implications for humans. (2017-05-16)

Missing protein restored in patients with muscular dystrophy
Advances in the treatment of muscular dystrophy: For the first time, a research team has succeeded in restoring a missing repair protein in skeletal muscle of patients with muscular dystrophy. Researchers from the University and the University Hospital of Basel, Department of Biomedicine and Clinic of Neurology, report their recent findings in the scientific journal Science Translational Medicine. (2014-08-20)

Cedars-Sinai research: Preclinical muscular dystrophy data shows promise
Cedars-Sinai Heart Institute researchers have found that an experimental compound may help stem the debilitating effects of muscular dystrophy by restoring normal blood flow to muscles affected by the genetic disorder. (2012-11-07)

Some muscular dystrophy patients at increased risk for cancer
People who have the most common type of adult muscular dystrophy also have a higher risk of getting cancer, according to a paper published today in the Journal of the American Medical Association. Patients with myotonic muscular dystrophy are at increased risk for cancer of the brain, ovary, colon, and the uterine lining known as the endometrium. (2011-12-13)

Waste not, want not: Role for caveolin-3 in muscular dystrophy
Muscular dystrophies are characterized by skeletal muscle weakness due to muscle fiber wasting and loss. Kawasaki Medical School researchers now show in the JCI that mice lacking caveolin-3 -- a protein that helps form a scaffold onto which other signaling molecules assemble at the cell plasma membrane -- increases the intracellular activity of myostatin, an inhibitor of muscle growth, and leads to muscle wasting. Myostatin inhibition may have potential as a therapy for certain muscular dystrophies. (2006-10-12)

Cardiac and respiratory function supported by abdominal muscles in muscular dystrophy
Using mouse models, researchers found that abdominal muscles may be severely involved in the muscular dystrophy process. The abdominal muscles are important to provide respiratory support when the diaphragm muscle has been damaged by the disease, so that additional abdominal muscle involvement can worsen the respiratory situation considerably. These findings are of great importance for understanding the progression of cardio-respiratory failure in the human disease. (2015-02-26)

Parent Project Muscular Dystrophy awards $600K to Nationwide Children's for gene therapy study
Parent Project Muscular Dystrophy, the largest nonprofit organization in the United States focused on finding a cure for Duchenne muscular dystrophy, announced that PPMD will award a $600,000 grant to Nationwide Children's Hospital in Columbus, Ohio, to conduct clinical testing of a promising gene therapy technique for muscle disease. (2010-08-10)

Sealing the deal to block heart failure in dogs with muscular dystrophy
Duchenne muscular dystrophy is a severe form of muscular dystrophy that is fatal. Due to advances in palliative respiratory care, heart failure is emerging as a leading cause of death from DMD, and there are no effective therapies for this fatal clinical consequence of DMD. However, new research using the golden retriever muscular dystrophy model of DMD suggests that membrane-sealant therapy could provide a new approach to treating DMD heart disease. (2010-03-15)

GW researcher finds genetic cause of new type of muscular dystrophy
George Washington University & St. George's University of London research, published in The American Journal of Human Genetics, outlines a newly discovered genetic mutation associated with short stature, muscle weakness, intellectual disability, and cataracts, leading researchers to believe this is a new type of congenital muscular dystrophy. (2017-02-09)

Designed proteins to treat muscular dystrophy
The cell scaffolding holds muscle fibers together and protects them from damage. Individuals who suffer from muscular dystrophy often lack essential components in this cell scaffold. As a result, their muscles lack strength and become progressively weaker. The research team of Professor Markus Rüegg at the Biozentrum, University of Basel, has now designed two proteins that stabilize the cell scaffolding link it to the muscle fiber and thereby restore muscle structure and function. (2017-06-28)

Blood-Flow Study Helps UT Southwestern Researchers Shed New Light On Childhood Muscular Dystrophy
Researchers at UT Southwestern Medical Center at Dallas have made a critical discovery about blood-flow regulation during exercise and, in the process, have uncovered a clue about a culprit behind Duchenne dystrophy, also known as childhood muscular dystrophy. (1998-12-08)

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