Neurodegenerative Diseases Current Events

Neurodegenerative Diseases Current Events, Neurodegenerative Diseases News Articles.
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Antioxidant therapies may help in the fight against neurodegenerative diseases
A new review examines the potential of antioxidant approaches for the treatment of neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease, amyotrophic lateral sclerosis, and multiple sclerosis. (2016-08-01)

Possible new treatment for neurodegenerative diseases found
Researchers at the University of Liverpool have found that a well-established anti-epileptic drug could also be used as a treatment for neurodegenerative diseases. (2015-10-13)

Prion-like proteins drive several diseases of aging
Two leading neurology researchers have proposed a theory that could unify scientists' thinking about several neurodegenerative diseases and suggest therapeutic strategies to combat them. (2013-09-05)

Therapeutic opportunities in neurodegenerative diseases
This conference will examine the latest research efforts towards understanding and treating neurodegenerative diseases such as Alzheimer's Disease, Parkinson's Disease, amyotrophic lateral sclerosis, and prion diseases. (2000-11-14)

New understanding can lead to srategies for dealing with neurodegenerative diseases
A new understanding of what takes place on the cellular level during the development of neurodegenerative diseases, such as Parkinson's, Alzheimer's, ALS and Huntington's diseases, offers promise towards possible new strategies for combating such diseases, say Hebrew University of Jerusalem researchers. (2012-12-06)

Oxidative stress, mitochondrial damage and neurodegenerative diseases
Oxidative stress and mitochondrial damage have been implicated in the pathogenesis of several neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. (2013-08-07)

New biomarkers could help doctors spot Alzheimer's and other neurodegenerative diseases
Neurodegenerative diseases like Alzheimer's and Parkinson's in their early stages can be difficult for physicians to spot, and many diagnoses are incorrect. The identification of hundreds of potential disease biomarkers by researchers at the University of Washington and Harborview Medical Center may soon help in the diagnosis of such diseases. (2006-08-11)

Autophagy and mitochondria: Targets in neurodegenerative disorders
Cellular homeostasis depends on the timely clearance of damaged cellular organelles and proteins via pathways including autophagy. Mitochondria and mitochondrial autophagy play a vital role in cellular health and failure of these pathways can have a devastating effect on cellular homeostasis. Here, the researchers review the involvement of mitochondrial and autophagy dysfunction in neurodegenerative disorders specifically focusing on Alzheimer's, Parkinson's and Huntington's disease. (2018-12-26)

Scientists identify molecular system that could help develop treatments for Alzheimer's disease
Scientists from the University of Southampton have identified the molecular system that contributes to the harmful inflammatory reaction in the brain during neurodegenerative diseases. (2013-02-21)

Progranulin and dementia -- a blood sample does not tell the full story!
The key neurodegeneration protein progranulin is regulated differently in cerebrospinal fluid than in serum. (2016-05-25)

DZNE and Charite work together: With joined forces against neurodegenerative diseases
The German Center for Neurodegenerative Diseases and Charité -- Universitätsmedizin Berlin are internationally leading institutions for research in the field of neurodegenerative diseases. (2013-05-16)

Novel pathology could improve diagnosis and treatment of Huntington's and other diseases
Bristol scientists have discovered a novel pathology that occurs in several human neurodegenerative diseases, including Huntington's disease. The article, published in Brain Pathology, describes how SAFB1 expression occurs in both spinocerebellar ataxias and Huntington's disease and may be a common marker of these conditions, which have a similar genetic background. (2020-06-30)

Special issue of Future Medicinal Chemistry explores advances in neurodegenerative disease therapy
Future Medicinal Chemistry, a leading MEDLINE indexed journal for medicinal chemists, has published two Special Focus issues on Medicinal Chemistry Advances in Neurodegenerative Disease Therapy. (2017-06-23)

Neuroinflammation in Alzheimer's and Parkinson's Diseases
This review focuses on four modifiable risk factors including physical inactivity, vascular disease-related conditions, obesity and type two diabetes mellitus, all of which have been identified as risk factors for the development of Alzheimer's Disease (AD) and Parkinson's Disease (PD). (2017-08-25)

Tracing a path toward neuronal cell death
Researchers at Brigham and Women's Hospital have developed a genetic model that is yielding new insights into what happens when astrocytes go awry. (2015-11-30)

Researcher discovers commonalities in brains of people with HD and PD
A new study strongly suggests that the brains of people who have died of Huntington's disease (HD) and Parkinson's disease (PD) show a similar response to a lifetime of neurodegeneration, despite being two very distinct diseases. (2018-01-12)

Drug combinations key in treating neurodegenerative diseases
Combining the benefits of multiple drugs in a single pill may hold the key to treating neurodegenerative diseases, Medical College of Georgia researchers say. (2009-01-30)

Advancing Neurodegeneration Drug Discovery and Development
Does having cancer decrease your risk of developing neurodegenerative diseases? Why do many cancer drug targets overlap with targets for neurodegenerative diseases? This meeting will address these questions to help advance therapeutic development. (2015-05-14)

Presented a program capable of detecting neurodegeneration biomarkers through magnetic
This tool is able to identify single-person neurodegeneration before the symptom's appearance, which could significate a more effective and personalized medicine. (2020-10-08)

Western researchers receive $600,000 to study Prion diseases and Alzheimer's
A team of researchers from The University of Western Ontario has received $600,000 from PrioNet Canada to study Prion diseases and Alzheimer's. Prion diseases are fatal, infectious and transmissible neurodegenerative diseases affecting both humans and animals including mad cow disease or bovine spongiform encephalopathy, Creutzfeldt-Jakob disease in humans, and chronic wasting disease in deer and elk. The team led by Marco Prado will investigate whether prion protein could be a therapeutic target in Alzheimer disease. (2011-07-20)

Powerful molecules provide new findings about Huntington's disease
Researchers at Lund University in Sweden have discovered a direct link between the protein aggregation in nerve cells that is typical for neurodegenerative diseases, and the regulation of gene expression in Huntington's disease. The results pave the way for the development of new treatment strategies for diseases that involve impairment of the basic mechanism by which the body's cells can break down and recycle their own component parts. This process, called autophagy, is disrupted in for example Huntington's and other neurodegenerative diseases. (2018-08-21)

Study identifies compound that reverses symptoms of Alzheimer's, Parkinson's
A new study describes an innovative strategy that reverses symptoms in these Alzheimer's disease and Parkinson's disease -- at least in fruit flies which had been genetically altered to model the diseases. (2016-04-25)

Conference focuses on drug abuse effects on neuroimmunity, infectious diseases
The 9th Conference on Neuroimmune Circuits & Infectious Diseases will be held Oct. 3 to 6 in at the Clearwater Beach Hilton, 400 Mandalay Ave. in Clearwater, FL. The latest research on the connection between drug abuse and the development of infectious diseases like HIV will be presented. (2002-09-25)

Janssen, J&J Innovation, VIB, KU Leuven and UZ Leuven join forces to combat neurological diseases
Stellar is launched to overcome the inefficiencies in translating basic molecular insights to diagnostics and therapeutics for neurodegenerative diseases. Janssen and Johnson & Johnson Innovation are committing up to 5 million Euros for this project over a five-year period. (2013-05-29)

Gene defect may point to solution for Alzheimer's
University of Bergen researchers have found a protein that could hold the key to understanding how Alzheimer's disease develops. (2016-04-13)

Potential indicator for the early detection of dementias
Researchers at the University of Basel have discovered a factor that could support the early detection of neurodegenerative diseases such as Alzheimer's or Parkinson's. This cytokine is induced by cellular stress reactions after disturbances of the mitochondria, the 'cell's power plants,' as neuropathologists write in the journal Cell Reports. (2018-08-07)

Protecting neurons could halt Alzheimer's, Parkinson's diseases
Scientists from two Texas universities have identified promising lead chemical compounds for the treatment of neurodegenerative disorders like Alzheimer's and Parkinson's diseases, major and growing health problems as the human life span increases. (2008-11-13)

Drug averts Parkinson's disease in fruit flies, suggesting new approach for humans
Scientists at the University of Pennsylvania have averted the onset of neurodegenerative disease in fruit flies by administering medication to flies genetically predisposed to a disorder akin to Parkinson's disease. The result suggests a new approach to the treatment of human disorders including Parkinson's and Alzheimer's diseases. (2002-11-11)

UTHealth student wins microbiology research fellowship
Jennifer Abrams, a graduate student at the University of Texas Health Science Center at Houston, has been awarded a three-year, $33,000 fellowship from the American Society for Microbiology to support her innovative research into the molecular causes of protein misfolding diseases like Alzheimer's, Lou Gehrig's and Parkinson's. (2010-09-20)

Tunneling nanotubes between neurons enable the spread of Parkinson's disease via lysosomes
Scientists from the Institut Pasteur have demonstrated the role of lysosomal vesicles in transporting α-synuclein aggregates, responsible for Parkinson's and other neurodegenerative diseases, between neurons. These proteins move from one neuron to the next in lysosomal vesicles which travel along the 'tunneling nanotubes' between cells. These findings were published in The EMBO Journal on Aug. 22, 2016. (2016-08-22)

PERK-opathies: Stress mechanism underlying neurodegeneration
The objective of the review is to highlight the impact of PERK in neurodegenerative processes and underscore the pathway as a reservoir of therapeutic targets. (2016-03-17)

Link between Alzheimer's and type 2 diabetes could lead to new treatment
Could a new treatment for Alzheimer's be found by studying type 2 diabetes? Dr. Jie Zheng and his team believe they have found a link that could lead to a single drug that treats both diseases. (2015-09-15)

Compound identified that protects against neurodegeneration
Researchers from the University of Liverpool have identified a new compound that protects against neurodegeneration in nematode worms. The discovery may enable novel treatments for human neurodegenerative diseases to be developed in the future. (2018-07-18)

Learning how the brain takes out its trash may help decode neurological diseases
Imagine that garbage haulers don't exist. Slowly, the trash accumulates in our offices, our homes, it clogs the streets and damages our cars, causes illness and renders normal life impossible. (2013-08-29)

Neurodegenerative diseases target healthy brain's intrinsic networks
New research suggests that neurodegenerative diseases are neither diffuse nor random but specifically target large-scale functional networks in the human brain. The study, published by Cell Press in the April 16 issue of the journal Neuron, may drive a new generation of network-based strategies for diagnosing and monitoring neurodegenerative diseases. (2009-04-15)

Researchers reveal how neurodegenerative diseases spread through the brain
Synapses, the place where brain cells contact one another, play a pivotal role in the transmission of toxic proteins. This allows neurodegenerative diseases such as Alzheimer's to spread through the brain. This the main conclusion of new research led by professor Patrik Verstreken (VIB-KU Leuven), in collaboration with Janssen Research & Development (Johnson & Johnson). If the spreading of these toxic proteins could be prevented, the progression of neurodegenerative diseases might be slowed down substantially. (2016-11-09)

Low levels of toxic proteins linked to brain diseases, study suggests
Neurodegenerative diseases such as Alzheimer's could be better understood thanks to insight into proteins linked to such conditions, a study suggests. (2013-07-02)

RNAs help molecules come together in liquid-like droplets within living cells
Researchers at the University of North Carolina at Chapel Hill collaborated to determine how proteins and messenger RNAs condense into liquid-like droplets within cells. The activity is a normal biological process, but it can lead to neurodegenerative diseases like Parkinson's disease when it goes awry. The researchers found that the process is regulated by molecules of RNA that recognize each other and combine based on the very specific and complex shapes of RNA molecules. (2018-04-12)

Broken signals lead to neurodegeneration
Researchers have discovered that a cell receptor widely involved in intracellular calcium signaling -- the IP3R receptor -- can be locked into a closed state by enzyme action, and that this locking may potentially play a role in the reduction of neuron signaling seen in neurodegenerative diseases such as Huntington's and Alzheimer's disease. (2014-09-08)

Study provides understanding of how nerve cells are damaged by accumulation of abnormal proteins
A new study has uncovered a molecular mechanism in the prion protein, a protein responsible for neurodegenerative diseases, which may explain why nerve cells degenerate in these disorders. The findings, which appear in the journal eLife, may one day lead to better therapies and treatments for these diseases (2017-05-25)

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