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Pain relief can now be based on solid evidence
A Cochrane Review of data relating to about 45,000 patients involved in approximately 350 individual studies has provided an evaluation of the effect you can expect to get if you take commonly used painkillers at specific doses. The review also identifies pain killers for which there is only poor or no reliable evidence. This review will help doctors and patients to make evidence informed decisions of which pain killers to use, and is published in the latest edition of the Cochrane Library. (2011-09-06)

Common lung exam often causes unneccessary pain: More pain control needed
A common, invasive procedure used to test for lung disease may be causing patients unnecessary pain, according to a new study. While most physicians always use topical anesthetic before flexible bronchoscopy (FOB), many believe that other pain killers aren't needed. Now, Johns Hopkins researchers have shown that, even when sedatives and analgesics are routinely used, some patients suffer pain. (2000-05-06)

Acupuncture relieves pelvic pain during pregnancy
Acupuncture and strengthening exercises help relieve pelvic girdle pain during pregnancy and are effective complements to standard treatment, finds a study published online by the BMJ today. (2005-03-17)

Limit sucrose as painkiller for newborns
Using sucrose to reduce pain in newborns undergoing painful procedures should be limited to babies having blood taken for the newborn screening test but not for intramuscular injections. (2008-06-30)

Rating your pain from 0 to 10 might not help your doctor
The most commonly used measure for pain screening -- which asks patients in primary care to rate their current pain from 0 (no pain) to 10 (worst pain) -- may only be modestly accurate, according to researchers from the Indiana University School of Medicine and the University of North Carolina. (2007-09-17)

First treatment for pain using human stem cells a success
Researchers at the University of Sydney have used human stem cells to make pain-killing neurons that provide lasting relief in mice, without side effects, in a single treatment. The next step is to perform extensive safety tests in rodents and pigs, and then move to human patients suffering chronic pain within the next five years. (2020-01-23)

Studies provide new insights on mosquito-borne chikungunya virus infection
The frequency of chronic joint pain after infection with chikungunya in a large Latin-American cohort was 25 percent at a median of 20-months post-infection. (2017-12-20)

Nocebo response, social observation, body-related cognitive styles published by DovePress
Recently, it has been shown that Nocebo hyperalgesia can be acquired through observational learning. The aim of this study was to investigate socially induced nocebo hyperalgesia and its relationship with pain catastrophizing, somatic complaints, hypochondriacal concerns and empathy. (2016-04-25)

Meaning of brain scans for 'pain' called into question
Patterns of brain activity thought to show pain responses have been called into question after researchers saw such patterns in rare patients born without a sense of pain. The study was designed to test the 'pain matrix,' a pattern of brain activity that is often considered a marker for pain. The association is so pervasive that the 'pain matrix' has been used in research to suggest that social rejection or mental effort can cause 'pain.' (2016-04-25)

Foot, knee and hip pain a problem in obese children
Pain in the lower extremities -- feet, ankles, knees and hips -- contributes to both poor physical function and a reduced quality of life in obese children, according to a new study by Dr. Sharon Bout-Tabaku and colleagues, from Nationwide Children's Hospital and The Ohio State University in the US. Their findings appear online in Clinical Orthopaedics and Related Research, published by Springer. (2012-10-16)

Does widespread pain stem from the brain? MRI study investigates
Patients with different chronic pain diagnoses recorded similar brain changes, a new study finds, suggesting a need for new treatment approaches. (2017-08-10)

Effectiveness of the WHO cancer pain relief guidelines published by Dove Medical Press
The WHO guidelines have been successful in making pain relief knowledge more available, but from a moral and ethical standpoint these guidelines need to be promoted and examined until adequate pain relief is reported in all possible cancer pain patients. (2016-07-25)

Back pain improves in first 6 weeks but lingering effects at 1 year
For people receiving health care for acute and persistent low-back pain, symptoms will improve significantly in the first six weeks, but pain and disability may linger even after one year, states a large study published in CMAJ. (2012-05-14)

Smokers suffer more back pain
Smokers suffer more chronic back pain. This was the result of the analysis of a questionnaire performed by Monique Zimmermann-Stenzel and her colleagues and published in the current edition of Deutsches Ă„rzteblatt International. (2008-07-01)

Cause of ongoing pain discovered
New research from the University of Bristol, UK, shows that it is undamaged nerve fibres that cause ongoing spontaneous pain, not those that are injured. This new understanding may help pharmaceutical companies formulate novel pain killers. (2006-01-24)

Study identifies factors associated with pain 1 year after breast cancer surgery
In a study that included more than 800 women who had undergone surgery for breast cancer, the majority reported some level of pain 12 months after surgery, and factors associated with pain included chronic preoperative pain, chemotherapy, preoperative depression and pain in the area to be operated, according to a study appearing in the January 1 issue of JAMA. (2013-12-31)

The Journal of Pain Research receives first impact factor of 2.363
Dove Medical Press are pleased to announce that the Journal of Pain Research has received its first Thomson Reuters Impact Factor, a score of 2.363. (2016-06-16)

Depression can lead to back pain
It is well documented that physical pain can lead to feelings of depression, but a new study from the University of Alberta shows the reverse can be true, as well. (2004-02-26)

How best to treat chronic pain? The jury is still out
A review of recent studies on pain medicine appearing in the June 2008 issue of the Journal of General Internal Medicine reports that while various approaches and combinations of therapies to treat pain have advantages and disadvantages, researchers don't yet know how to determine which is best for individual patients. (2008-06-05)

Study shows link between smoking and chronic pain in women
Kentucky women who smoke heavily may experience more chronic musculoskeletal pain, suggests a new study led by University of Kentucky researchers. (2011-09-28)

Back pain? Move, don't rest!
Move if you have back pain, this is the advice of a researcher at the Sahlgrenska Academy, University of Gothenburg. Patients with acute low back pain who were advised to stay active despite the pain fared better than those who were told to adjust their activity in line with their pain. (2011-09-19)

New procedure allows diagnosis of lower back pain cause
Functional anesthetic discography (FAD), a new diagnostic procedure involving injecting anesthetic directly into a spinal disc, can be used to confirm the presence of injured discs as the source of a patient's lower back pain symptoms, according to a new study by researchers from Winthrop-University Hospital in Mineola, N.Y. (2007-05-04)

Etoricoxib provides long lasting pain relief after surgery
Oral etoricoxib is at least as effective as other drugs commonly used for pain relief after surgery. A Cochrane Systematic Review has confirmed the effectiveness of the drug, which is sold under the brand name of Arcoxia. (2009-04-14)

Many cancer patients receive insufficient pain management therapy
Pain is one of the most common symptoms of cancer patients, yet many of them do not receive adequate therapy for the pain caused by their disease or treatments, according to a study in the Sept. 1 issue of the International Journal of Radiation Oncology, Biology, Physics, the official journal of the American Society for Therapeutic Radiology and Oncology. (2008-09-09)

Study links diabetes and back pain
People with diabetes have a 35 percent higher risk of experiencing low back pain and 24 percent higher risk of having neck pain than those without diabetes, a review by University of Sydney researchers has found. (2019-02-21)

Does it hurt?
It is well known that pain is a highly subjective experience. We each have a pain threshold, but this can vary depending on distractions and mood. A paper in the International Journal of Behavioral and Healthcare Research offers a cautionary note on measuring perceived pain in research. (2011-01-10)

Researchers find anti-depressants reduce pain in opioid-dependent patients
In what is believed to be the first study of its kind to demonstrate an association between the antidepressant escitalopram and improved general pain, researchers from Boston University School of Medicine, have found that opioid-dependent patients treated with escitalopram experienced meaningful reductions in pain severity and pain interference during the first three months of therapy. (2011-11-03)

Better diagnosis of pain in children
None of the more than 15 different methods of measuring pain levels in children under four produces a useful, reliable result. A new method, based on research by NWO, looks set to change this situation. Using the new pain observation scale will make it possible to evaluate pain effectively in children aged up to four. (1999-09-17)

Loyola study finds women suffer more neck pain than men
Women are 1.38 times more likely than men to report neck pain due to cervical degenerative disc disease, according to a study presented at the annual meeting of the American Academy of Pain Medicine in Palm Springs, Calif. (2016-03-08)

Opioids provide relief from neuropathic pain
The pain that is associated with injury to nerves is known as neuropathic pain. It can be extremely debilitating, and treatments show limited or no effectiveness. Researcher performed using a mouse model of neuropathic pain has led to the suggestion that selectively targeting opioid-containing immune cells at sites of nerve injury could provide natural pain relief and offer a novel approach for neuropathic pain. (2009-01-12)

Anticonvulsant drugs ineffective for low back pain and can cause harm, despite increased prescribing
Anticonvulsant drugs are increasingly being used to treat low back pain, but a new study in CMAJ (Canadian Medical Association Journal) finds they are ineffective and can have adverse effects. (2018-07-03)

Sometimes just watching hurts -- and the signs of pain are seen in the brain
Some people claim to experience pain just watching something painful to happen. In complex regional pain syndrome (CRPS) patients, both own movements and observing other persons' movements may aggravate the pain. Researchers found that when CRPS patients feel pain caused by observing other person's movements, their brains display abnormal activation in many areas that respond to normal physical pain. Thus the pain the CRPS patients felt during movement observation presented similarities to the 'normal' pain. (2016-11-29)

Imaging pain
Using human brain imaging techniques, Dr. Catherine Bushnell, Director of the Anesthesia Research Unit at McGill University, studied how the human brain is activated when a person experiences pain. She found that the complex experience of pain results from activation in several regions of the cerebral cortex. (2000-02-18)

No justification for laparoscopic adhesiolysis to relieve abdominal pain
Authors of a study in this week's issue of The Lancet provide evidence that laparoscopic adhesiolysis cannot be recommended as a treatment for adhesions in patients with chronic abdominal pain. (2003-04-10)

Lack of research forcing elderly to cope with chronic pain
Annually, over 4,000 studies related to pain are published while only one percent of those look at pain and aging. There is a clear need for more investigators from many fields to further the efforts of current researchers, according to a recent paper published in the Journal Pain Medicine. (2006-04-18)

Higher pain tolerance in athletes may hold clues for pain management
Investigators from the University of Heidelberg have conducted a meta-analysis of available research and find that in fact, athletes can indeed tolerate a higher level of pain than normally active people. However, pain threshold, the minimum intensity at which a stimulus is perceived as painful, did not differ in athletes and normal controls. Their findings are published in the June issue of Pain. (2012-05-17)

Onset of forearm pain can be predicted
The concept that forearm pain is caused purely by repetitive movements of the arms or wrists, particularly in the workplace, is called into question in this week's BMJ. (2000-09-14)

The brain is able to anticipate painful movements following injury
When people are injured, how does the brain adapt the body's movements to help avoid pain? New research published in The Journal of Physiology investigates this question. (2018-05-31)

Exercise therapy best for knee pain
For patients with severe knee pain, supervised exercise therapy is more effective at reducing pain and improving function than usual care, finds a study published on today. (2009-10-20)

Plant used in Chinese medicine fights chronic pain
A plant used for centuries as a pain reliever in Chinese medicine may be just what the doctor ordered, especially when it comes to chronic pain. A key pain-relieving ingredient is a compound known as dehydrocorybulbine found in the roots of the flowering plant Corydalis, a member of the poppy family, according to researchers who report their findings in the Cell Press journal Current Biology on January 2. (2014-01-02)

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