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Pain Current Events, Pain News Articles.
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Scripps Florida scientists awarded $3 million to develop new, more effective pain treatments
Scripps Florida scientists have been awarded $3.1 million by the National Institute on Drug Abuse, part of the National Institutes of Health, to study and develop several new compounds that could prove to be effective in controlling pain without the unwanted side effects common with opiate drugs, such as morphine, Oxycontin®, and Vicoden®. (2012-02-29)

Mice feel others' pain -- literally
Pain sensitivity associated with alcohol withdrawal may activate the same brain region in both drinking and non-drinking mice, finds a study published in eNeuro. (2017-07-24)

Newer pain management strategies can lead to quicker, shorter recovery after TKRs
According to a new literature review in the February issue of the Journal of the American Academy of Orthopaedic Surgeons, a team-based care approach (consisting of the patient, family members, the orthopaedic surgeon and other medical practitioners) on total knee replacement (TKR) procedures, in conjunction with newer pain management strategies, is key to maximizing patient outcomes. (2016-02-08)

Research explores links between physical and emotional pain relief
Though we all desire relief -- from stress, work, or pain -- little is known about the specific emotions underlying relief. New research explores the psychological mechanisms associated with relief that occurs after the removal of pain, also known as pain offset relief. (2013-03-21)

Paracetamol is ineffective for lower back pain
Paracetamol is not effective in the treatment of spinal pain and provides negligible benefits for osteoarthritis, according to a study published in The BMJ today. (2015-03-31)

Researchers recommend multidisciplinary approach of low back pain
Researchers calculated the costs of management of low back pain and found that an integrated and step-wise approach within a multidisciplinary setting forms a better use of the available resources. The study is published in the September issue of Pain Practice. (2005-09-07)

News tips from the Journal of Neuroscience
News tops for Journal of Neuroscience includes the following: Perceived controllability modulates the neural response to pain, and neuronal nicotinic receptor antibodies and autonomic neuropathy. (2004-08-11)

Study shows pain causes older adults to develop more inflammation over time
When older relatives complain about their pains, show a little empathy, because new research suggests that as we age, we may all become more sensitive to pain. A small, preliminary University of Florida Health study has suggested for the first time that inflammation may occur more quickly and at a higher magnitude -- and stays around longer -- when older adults experience pain versus when younger adults experience pain. (2016-05-04)

Spinal cord neurons that control pain and itch
The spinal cord transmits pain signals to the brain, where they are consciously perceived. But not all the impulses arrive at their destination: Certain neurons act as checkpoints and determine whether a pain signal is relayed or not. Researchers from UZH identified these neurons and their connections. Moreover, they developed means to specifically activate these neurons, which reduces not only pain -- but astonishingly also alleviates itch. (2015-03-19)

Gabapentinoids appear increasingly to be prescribed, off-label, for cancer pain
Between 2005 and 2015, as the opioid crisis in America came into focus, prescriptions for gabapentinoid medications -- gabapentin and pregabalin -- to adults with cancer saw a two-fold increase, a University of Michigan Rogel Cancer Center study has found. (2019-10-28)

Most patients with chronic kidney disease may experience long-term pain
In a study of patients with pre-dialysis chronic kidney disease, most patients reported chronic pain. More severe pain was linked with both proper and improper use of pain medications. (2015-02-19)

Opioids vs. placebo, nonopioid alternatives for chronic noncancer pain
An estimated 50 million adults in the United States were living with chronic noncancer pain in 2016 and many of them were prescribed opioid medications, even though a clinical benefit is uncertain. This study combined the results of 96 randomized clinical trials with about 26,000 participants to compare opioids with placebo and nonopioid alternative pain medications for the treatment of chronic noncancer pain. (2018-12-18)

Muscle relaxant or opioid combined with NSAID does not improve low back pain
Among patients with acute, low back pain presenting to an emergency department, neither the nonsteroidal anti-inflammatory drug naproxen combined with oxycodone/acetaminophen or the muscle relaxant cyclobenzaprine provided better pain relief or improvement in functional outcomes than naproxen combined with placebo, according to a study in the Oct. 20 issue of JAMA. (2015-10-20)

Mirrors can trick the brain into recovering from persistent pain, research suggests
Looking in a mirror at a reflection of their healthy hand could help people with persistent pain ease their symptoms and eventually overcome their problem, say scientists in the latest edition of the journal Clinical Medicine. (2005-10-31)

Neuroscientists find 'gatekeeper' in itching sensations plays no role in pain transmission
A neurotransmitter study in mice found that BNP is involved in relaying itching sensations but not pain. A better understanding of pain and itch pathways could help researchers develop targeted therapies for diseases with chronic itching, including multiple sclerosis and kidney failure. (2017-10-03)

IUPUI psychologists explore pain in Hispanic Americans
Hispanic-Americans report fewer pain conditions compared with non-Hispanic white or black Americans, according to a critical review and analysis of more than 100 studies on pain experience and pain management among Hispanic-Americans. The first work of its type was conducted by researchers from the School of Science at Indiana University-Purdue University Indianapolis. (2016-03-15)

An end to cancer pain?
A new study led by University of Toronto researcher Dr. David Lam has discovered the trigger behind the most severe forms of cancer pain. Released in top journal Pain this month, the study points to TMPRSS2 as the culprit: a gene that is also responsible for some of the most aggressive forms of androgen-fueled cancers. (2015-04-23)

The anatomy of pain
Emotions consist of general components that are also elicited by similar impressions and specific components. (2016-03-23)

U. Iowa study finds biological link between pain and fatigue
A recent University of Iowa study reveals a biological link between pain and fatigue and may help explain why more women than men are diagnosed with chronic pain and fatigue conditions like fibromyalgia and chronic fatigue syndrome. (2008-04-07)

Ultrasound for children with broken arms: Accurate, faster, less painful than X-rays
Point-of-Care Ultrasound (POCUS) assessment of distal forearm injuries in children is accurate, timely, and associated with low levels of pain and high caregiver satisfaction. (2017-05-08)

Arthritis self-management does not reduce pain levels or GP visits
Self-management programs for people with osteoarthritis do not reduce pain, or the number of visits patients make to their GP, a new study reveals today. (2006-10-13)

Antioxidants: New kid on the block for pain relief?
Antioxidant-based pain killers may one day become a viable alternative to addictive medications such as morphine. Researchers found that synthetic antioxidants practically eradicated pain-like behavior in nearly three-quarters of mice with inflamed hind paws. (2006-11-07)

SLU researcher finds an off switch for pain
Researchers have discovered a way to block a pain pathway in animal models of chronic neuropathic pain suggesting a promising new approach to pain relief. (2014-11-26)

First Nations children and youth experiencing more pain than non-First Nations children
First Nations children and youth are experiencing more pain than non-First Nations children, but do not access specialist or mental health services at the same rate as their non-First Nations peers, found new research published in CMAJ (Canadian Medical Association Journal). (2018-12-10)

Ronald Dubner named 2012 AADR Distinguished Scientist
The American Association for Dental Research has announced that Ronald Dubner, University of Maryland, Baltimore, is the recipient of the 2012 AADR Distinguished Scientist Award. This award will be presented to Dubner at the 41st AADR Annual Meeting & Exhibition in Tampa, Fla., on March 21, 2012. (2012-03-21)

Managing chronic bone and joint pain
Musculoskeletal pain of the bone, joint and muscles is one of the most common reasons for primary care visits in the United States. (2014-02-19)

Brain processes ongoing pain more emotionally
A momentary lapse of concentration is all it takes for a finger to become trapped or sprain an ankle -- and it hurts. Pain is the body's protective mechanism and a complex neurological phenomenon. Moreover, ongoing pain in the sense of chronic pain can be a disease. Scientists from Technische Universität München have now demonstrated that already during a few minutes of ongoing pain, the underlying brain activity changes by shifting from sensory to emotional processes. (2015-03-11)

Efficacy of glucosamine, chondroitin sulfate may depend on level of osteoarthritis pain
The popular dietary supplements glucosamine and chondroitin sulfate proved no better than a placebo in relieving osteoarthritis knee pain in most participants of a major national trial. But the study, published in the Feb. 23 issue of the New England Journal of Medicine, also showed a smaller subgroup of trial patients with moderate to severe osteoarthritis knee pain taking the combination of the two supplements experienced significant pain relief. (2006-02-22)

Scientists tap into spinal response from gastric reflux
University of Adelaide researchers have made advances in the understanding of one of the world's most common medical conditions, gastric reflux, and how patients experience pain from it. (2013-10-01)

Post-surgical patch releases non-opioid painkiller directly to the wound
A Duke-led team of scientists has developed a bio-compatible surgical patch that releases non-opioid painkillers directly to the site of a wound for days and then dissolves away. The polymer patch provides a controlled release of a drug that blocks the enzyme COX-2 (cyclooxygenase-2,) which drives pain and inflammation. The study appears Jan. 10, 2021 in the Journal of Controlled Release. (2021-01-11)

'Like magic!' is how Rodney Blauer describes the results of his two endoscopic brain surgeries in less than a year
After undergoing two highly specialized types of minimally invasive skull base brain surgery in less than a year 69-year-old Rodney Blauer says he is feeling great this holiday season. (2001-12-03)

Women need less morphine after hysterectomies with new treatment
Women recovering from hysterectomies require less morphine to combat pain and are able to recover their lung function more quickly when they receive a combination of two non-morphine-like or (2005-01-04)

Burning pain and itching governed by same nerve cells
We all know how hard it is not to scratch when we have an itch. But how can an itch be alleviated? In a new study published today in the prestigious journal Neuron, researchers at Uppsala University present the surprising finding that the same nerve cells that are active when we experience heat pain are also associated with itching. (2010-11-04)

Post-surgical opioids can, paradoxically, lead to chronic pain
Giving opioids to animals to quell pain after surgery prolongs pain for three weeks and primes specialized immune cells in the spinal cord to be more reactive to pain, according to a new study by the University of Colorado Boulder. The authors say the paradoxical findings could add a new wrinkle to the conversation about the national opioid epidemic. (2018-04-16)

Transporter is possible target for safer pain medicine
A transporter that silences one of the body's natural pain killers holds promise for new powerful, non-addictive pain medicines as well as understanding AIDS patients' increased pain perception, researchers say. (2006-06-09)

Stem cells provide lasting pain relief in mice
Duke researchers have identified a promising stem cell based-therapy to address the chronic pain that affects more than one-third of the US adult population. In mice, bone marrow stromal cells were found to provide lasting relief for chronic pain caused by nerve damage. The findings also may advance cell-based therapies in chronic pain conditions, lower back pain and spinal cord injuries. (2015-07-13)

New pain research: Routine Tylenol for nursing home residents with dementia increases activity
A Saint Louis University study finds that routine doses of acetaminophen energize nursing home residents who have moderate to severe dementia and are likely to have chronic pain. (2005-11-30)

Hopkins children's experts say doctors and parents can sort out symptoms with a checklist
A young child arrives at the emergency room after several days of abdominal pain, vomiting, and diarrhea and is sent home with a diagnosis of viral gastritis and treatment for the symptoms. The child seems better for a while, only to return to the ER with worse symptoms and a ruptured appendix, a life-threatening complication of appendicitis. (2008-10-06)

Dectin-1-mediated pain is critical for the resolution of fungal inflammation
Candidiasis is a painful infection that affects a large number of individuals, occasionally causing severe pain that is solely controlled by resolution of infection. Here, Dectin-1 inhibition was found to block pain during fungal infection. Osaka University researchers found that clodronate, a drug that is currently used for osteoporosis treatment, could suppress severe pain in fungal infection, and that the Dectin-1 pathway could be an important new target for treatment of pain. (2018-08-29)

Children exposed to secondhand tobacco or cooking smoke have very high rates of pain and complications after tonsillectomy
New research presented at this year's Euroanaesthesia meeting in Stockholm shows that children exposed to indoor coal-burning stoves and/or second-hand tobacco smoke are much more likely to suffer postoperative complications and excessive pain after tonsillectomies. (2014-06-01)

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