Placenta Current Events

Placenta Current Events, Placenta News Articles.
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Placenta removal -- a safer method after Caesareans
In Caesarean deliveries the placenta is usually removed by hand or by a technique known as 'cord traction'. A recent systematic review by Cochrane researchers shows that cord traction poses less risk to the mother than manual removal. (2008-07-15)

Blood vessel forming potential of stem cells from human placenta and umbilical cord blood
This study compared endothelial colony-forming cells derived from human placenta to those derived from human umbilical cord blood to find which were more proliferative and better at forming new blood vessels. Circulating ECFCs from umbilical cord blood and those from human placenta are phenotypically identical with equivalent proliferative potential. However, researchers found that ECFCs from placenta formed significantly more blood vessels than those derived from umbilical cord blood. The placenta-derived cells were also more vasculogenic. (2012-07-19)

Research reveals the placenta's oxygen tanks for early embryos
A new role for the placenta has been revealed by University of Manchester scientists who have identified sites which store, and gradually release, oxygen for newly formed embryos in the weeks after the baby's heart is developed. (2015-09-10)

Yale scientists develop 'gas gauge' to prevent pregnancy loss
To combat the many fetal deaths that occur annually because the placenta is too small, researchers at Yale School of Medicine have developed a method to measure the volume of the placenta, which provides nourishment to the fetus. (2009-08-02)

Stress during pregnancy can affect fetal development
Stress hormones in the mother can affect fetal development, according to a study published today in The Journal of Physiology. (2015-01-25)

3D modelling identifies nutrient exchange in the human placenta
New findings published today in Science Advances, detail three-dimensional imaging research by a group of scientists at The University of Manchester and St Mary's Hospital. The research has opened up understanding about this vital life-sustaining process by mathematically modelling the human placenta. (2019-04-17)

Filling a niche -- role of Rb in mammalian stem cells
In the January 1 issue of G&D, Drs. Gustavo Leone and Michael Robinson (Ohio State University) and colleagues uncover a stem-cell specific role for the well-known tumor suppressor gene, Rb, in the developing mammalian embryo. (2006-12-31)

Liverpool placenta study could save lives
An important new study has been launched by the University of Liverpool and Liverpool Women's Hospital (LWH), to test a new treatment for 'retained placenta'- a condition where the placenta does not come out naturally after childbirth. (2005-05-10)

MRI pregnancy study gives new insights into the all-important placenta
MRI research has revealed detailed new insights into how the placenta works in pregnancy and discovered a completely new phenomenon where the placenta contracts every now and then. (2020-05-28)

Researchers design placenta-on-a-chip to better understand pregnancy
National Institutes of Health researchers and their colleagues have developed a 'placenta-on-a-chip' to study the inner workings of the human placenta and its role in pregnancy. The device was designed to imitate, on a micro-level, the structure and function of the placenta and model the transfer of nutrients from mother to fetus. This prototype is one of the latest in a series of organ-on-a-chip technologies developed to accelerate biomedical advances. (2015-06-18)

In preeclampsia, researchers identify proteins that cause blood vessel damage
Proteins released by the placenta may damage blood vessels in women with preeclampsia (PE), according to an abstract presented by Yale School of Medicine researchers at the Society for Gynecologic Investigation Conference March 17 in Reno, Nev. (2007-03-17)

Villous tree model with active contractions for estimating blood flow conditions
Perfusion in the human placenta is an important physiological phenomenon which shows the placental conditions. The magnitude of placental perfusion can be evaluated by 3-D power Doppler and contrast-enhanced MR images, but the direction has been hardly indicated. The computational model of the villous tree developed in this study will help to indicate the direction and the mechanical properties of the villous tree. (2017-06-20)

Battle between the placenta and uterus could help explain preeclampsia
A battle that brews in the mother's womb between the father's biological goal to produce the biggest, healthiest baby possible vs. the mother's need to live through delivery might help explain preeclampsia, an often deadly disease of pregnancy. The fetus must be big enough to thrive, yet small enough to pass through the birth canal. In a new study, Yale researchers describe the mechanism that keeps these conflicting goals in balance. (2011-10-11)

Imaging reveals unexpected contractions in the human placenta
High-resolution imaging of the human placenta provides new insights into blood circulation patterns that are crucial for fetal development, according to a study publishing May, 28 2020 in the open-access journal PLOS Biology by Penny Gowland of the University of Nottingham, and colleagues. These findings improve our understanding of the functioning of this understudied organ, both in healthy pregnancies and in serious medical conditions such as pre-eclampsia. (2020-05-28)

New theory may help demystify pregnancy-related condition
Preeclampsia, a late-pregnancy disorder that is characterized by high blood pressure and organ damage, may be caused by problems related to meeting the oxygen demands of the growing fetus, experts say in a new Anaesthesia paper. (2014-11-13)

Placenta pathology may clarify racial disparities in preemie health outcomes
African-American infants are twice as likely to die in the first year of life than white infants, for reasons that are complex and not well understood. Results from a recent study suggest that specific abnormalities in the placenta from African-American preterm births may hold clues to the physical mechanisms behind racial disparities in preemie health outcomes. (2019-10-03)

Miscarriage and infertility treatment increase pre-eclampsia risk
Repeated miscarriages and hormone treatment for infertility give an increased risk of pre-eclampsia among pregnant women. This comes from a new study from the Norwegian Institute of Public Health. More than 20,000 first-time mothers from the Norwegian Mother and Child Cohort Study are included in the study. (2008-12-18)

Clues to ancestral origin of placenta emerge in Stanford study
Researchers at the Stanford University School of Medicine have uncovered the first clues about the ancient origins of a mother's intricate lifeline to her unborn baby, the placenta, which delivers oxygen and nutrients critical to the baby's health. (2008-04-14)

Study: Maternal placenta consumption causes no harm to newborns
A joint UNLV and Oregon State University study found mothers who consumed their placenta passed on no harm to their newborn babies when compared to infants of mothers who did not consume their placenta. (2018-05-03)

Placentas adapt when mothers have poor diets or low oxygen during pregnancy
Cambridge researchers have discovered the placenta regulates how much oxygen and nutrients it transports to babies during challenging pregnancies in the first study of its kind. The placenta is one of the least understood human organs and it is notoriously difficult to study. This new research focused on analysing the placental mitochondria and it is hoped the new findings could lead to tests to determine whether a mother's placenta is functioning properly. (2019-01-18)

A key to pregnancy-associated malaria
A malaria protein that traps infected cells in the placenta may provide a promising new target for a vaccine against pregnancy-associated malaria (PAM). Salanti and colleagues show that the malaria protein VAR2CSA is displayed on malaria-infected cells that bind to the placenta, as they report in the November 1 issue of The Journal of Experimental Medicine. This causes a dangerous infection, which puts both mother and developing child at risk. (2004-11-01)

Vitamin D found to fight placental infection
In a study posted on Biology of Reproduction, Papers in Press, researchers report for the first time that vitamin D induces immune responses in placental tissues, suggesting that the ability of the placenta to combat bacterial infection may be enhanced if pregnant women supplement their diets with vitamin D. (2008-12-01)

Tumor-suppressor gene is critical for placenta development
An important cancer-related gene may play a critical role in the development of the placenta, the organ that controls nutrient and oxygen exchange between a mother and her fetus during pregnancy, and perhaps in miscarriages. Those conclusions come from a new study of the retinoblastoma (Rb) gene in mice. In humans, this gene, when mutated, raises the risk of a rare cancer of the eye called retinoblastoma. (2007-01-09)

Research unlocks critical early nutrient supply for embryos
The mechanism by which embryos receive nutrition during the first 11 weeks of pregnancy has been revealed by University of Manchester scientists. (2015-04-30)

Peptide payload
Erkki Ruoslahti and colleagues provide proof of principle for safe, targeted delivery of drugs to the placenta during pregnancy. (2016-05-06)

Higher risk of maternal complications/preterm deliveries for women undergoing multiple cesareans
The risk of maternal complications and preterm deliveries is significantly higher for women undergoing their fifth or more caesarean section, finds a new study published today in BJOG: An International Journal of Obstetrics and Gynaecology. (2012-10-31)

Placental malaria research funded by March of Dimes
The March of Dimes Foundation, an American organization that works to improve pregnancy and baby health, has now funded Carlos Penha-Goncalves' laboratory, at the Instituto Gulbenkian de Ciencia, for their studies on factors and mechanisms involved in placental malaria. This is the first time that this American Foundation funds research from a Portuguese Institution. (2015-06-02)

Babies burdened by environmental estrogens in mothers' wombs
Early childhood life in the womb is particularly sensitive to the effects of environmental pollutants. A team from Empa and the University of Vienna has now for the first time been able to show how a pollutant from contaminated food - the environmental estrogen zearalenone - spreads in the womb and is metabolized into harmful metabolites. (2019-10-10)

Simple twist of DNA determines fate of placenta
The development of the mammalian placenta depends upon an unusual twist that separates DNA's classic double helix into a single-stranded form, Yale researchers report July 15 in the journal Nature. (2020-07-15)

Placenta consumption offers few benefits for new moms
UNLV research finds that consuming encapsulated placentas has little to no effect on postpartum mood and maternal bonding; detectable changes shown in hormones. (2017-12-01)

3-D-bioprinted placenta could lead to new treatments for preeclampsia
Preeclampsia is a pregnancy complication involving the placenta that can be serious -- even fatal -- for the mother or fetus. The only effective treatment option is premature delivery. Now for the first time, scientists have bioprinted a 3-D model of placenta tissue that mimics the organ's complex structure. The model, reported in the journal ACS Biomaterials Science & Engineering, could lead to a better understanding of preeclampsia and the development of new treatments. (2016-05-18)

Circulation favors placenta over brain in fetuses of diabetic mothers
Blood flows preferentially to the placenta instead of the brain in fetuses of mothers with diabetes, reveals research presented today at EuroEcho-Imaging 2016. (2016-12-10)

Mother's stress hormone levels may affect fetal growth and long term health of child
Increased levels of stress hormones can lead pregnant mice to overeat, but affect growth of the fetus and, potentially, the long term health of the offspring, according to a study published today. (2015-01-26)

2 repressor genes identified as essential for placental development
Two particular repressor genes in a family of regulatory genes are vital for controlling cell proliferation during development of the placenta. Their absence in stem cells results in a placenta made up of overcrowded and poorly organized cells that cannot properly transport oxygen and nutrients or support normal embryonic development. The study show how these genes control cell proliferation in living animals. (2012-04-16)

A single missing gene leads to miscarriage
A single gene of the mother plays such a crucial role in the development of the placenta that its dysfunction leads to miscarriages. Researchers from the Medical Faculty of Ruhr-Universit├Ąt Bochum (RUB) have observed this in so-called knockout mice that were specifically modified for this purpose. These mice lack the gene for the transcription factor Math6. By conducting further analyses, the research team is now hoping to gain new insights into the role the gene plays in recurrent miscarriage in humans. (2018-10-19)

Placenta reflects arsenic exposure in pregnant women and fetuses, Dartmouth study shows
The placenta can be used to reliably measure arsenic exposure in pregnant women and how much of the toxic metal is transferred to their fetuses, a Dartmouth College study shows in the largest ever analysis of household drinking water arsenic and the mother-to-fetus connection. (2015-04-02)

Malaria parasites use camouflage to trick immune defences of pregnant women
Researchers from Copenhagen University Hospital and the University of Copenhagen have discovered why malaria parasites are able to hide from the immune defenses of expectant mothers. (2011-07-11)

Deakin University researcher unveils pregnancy mystery
A Deakin University study has unlocked one of the many mysteries of pregnancy -- how the trace element copper is transported across the placenta. The findings provide a lead to the possible cause, treatment and prevention of a number of potentially fatal conditions. (2007-03-05)

NIH-funded study: Placenta imaging method may aid diagnosis of pregnancy complications
A new imaging technique to track maternal blood flow to the placenta has the potential to help diagnose several common complications in early pregnancy, according to a study funded by the National Institutes of Health. Researchers used the technique, referred to as pseudo-continuous arterial spin labeling magnetic resonance imaging (pCASL MRI), to identify women with reduced placental blood flow who later developed one or more complications. (2019-11-06)

Drinking alcohol even at conception damages placenta development
Alcohol consumption during pregnancy can have disastrous consequences for the developing fetus, leading to low birth weight and fetal alcohol syndrome. Now, a team of researchers at the University of Queensland, Australia, publishes their discovery that drinking alcohol around the time of conception markedly restricts the growth of the placenta in soon-to-be rat mums, providing potential new clues for the causes of conditions like fetal growth restriction in people. (2019-06-10)

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