Prognosis Current Events

Prognosis Current Events, Prognosis News Articles.
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Does marital status affect prognosis after breast cancer diagnosis?
In a Cancer Medicine study of 298,434 patients diagnosed with breast cancer between 2004 and 2012, married patients had a better prognosis than patients who were single, who in turn had a better prognosis than those who were divorced, separated, or widowed. (2019-07-03)

Many adults have insufficient knowledge about heart failure
In the largest German survey on heart failure to date, investigators found that the overall awareness of heart failure has not increased over the past decade and is not at a satisfactory level. (2017-03-22)

Communication breakdown? Mismatch in expectations about prognosis in advanced cancer
A new study in JAMA Oncology finds that advanced cancer patients report far more optimistic expectations for survival prognosis than their oncologists, due to patients' misunderstanding of their oncologists' clinical judgment. (2016-07-14)

Prescription for palliative care: 4 points to improve discussions about dying
In an editorial appearing in the October 25 issue of The New England Journal of Medicine, medical oncologists at Johns Hopkins and Brigham and Women's hospitals provide a four-point plan for integrating palliative care discussions throughout the treatment of patients with terminal illnesses. (2012-10-24)

Study pinpoints opportunity for oncologists to improve prognosis communication
After communicating test results, an oncologist who asks, 'Would you like to talk about what this means?' gives patients permission to explore a serious discussion about life and death. (2017-01-24)

6 months after treatment start could be optimum time for making prognosis in HIV/AIDS
An international study in this week's issue of THE LANCET suggests that prognosis for patients with HIV/AIDS might be more reliably determined six months after initiation of highly active antiretroviral therapy (HAART), rather than before the start of treatment. (2003-08-28)

Physicians, surrogates often do not agree on a patient's likelihood of survival
Among critically ill patients, expectations about prognosis often differ between physicians and surrogate decision makers, and the causes are more complicated than the surrogate simply misunderstanding the physicians' assessments of prognosis, according to a study appearing in the May 17 issue of JAMA. (2016-05-17)

Detection of glycoprotein could indentify ovarian and uterine cancers with poor prognosis
The detection of a specific protein molecule could help oncologists identify uterine and ovarian cancers with poor prognosis and thereby enable better disease management of women with aggressive uterine or ovarian cancer, suggest authors of a study in this week's issue of THE LANCET. (2003-09-11)

Extrahepatic bile duct cancer produces granulocyte colony-stimulating factor?
A rare case of extrahepatic bile-duct carcinoma which reported recently indicated multiple distant metastasis despite of localized primary lesion. Moreover, granulocyte colony-stimulating factor produced by the carcinoma made pathological diagnosis difficult. This case implies that facing leukocytosis of cancer patients and difficulties on diagnosis, granulocyte colony-stimulating factor (G-CSF) in serum should be examined. (2008-05-14)

Low breast density in mammography worsens breast cancer prognosis
Very low mammographic breast density worsens the prognosis of breast cancer, according to a recent study from the University of Eastern Finland. Disease free survivals as well as overall life expectancies were significantly shorter in women with very low-density breasts in comparison to women with high-density breast tissue. The lower the breast tissue density, the less fibroglandular tissue there is compared to fat tissue. (2015-03-12)

Breast cancer prognosis associated with oncometabolite accumulation
In this issue of the Journal of Clinical Investigation Stefan Ambs and colleagues at the National Cancer Institute discovered an association between the oncometabolite 2-hydroxyglutarate levels, DNA methylation patterns, and breast cancer prognosis. (2013-12-09)

Communication between physicians and patients important for expectations
Seriously ill patients undergoing hemodialysis are more optimistic about their prognosis and prospects for transplants than their nephrologists, according to a study published online by JAMA Internal Medicine. The study also found that nephrologists rarely had discussed estimates of life-expectancy with their patients. (2013-05-27)

Who gets a transplant organ
A Rutgers study examines how decisions are made when it comes to allocating scare resources. Imagine 12 patients who need new kidneys, and six kidneys available. How would you allocate them? New research by Rutgers social psychologists suggests your answer would depend on how the patients and their situations are presented to you. (2015-09-02)

B cells linked to effective cancer immunotherapy
Cancer patients responded better to immunotherapy and had a better prognosis if their melanoma tumors contained specific clusters of B cells, according to new research from Lund University in Sweden. The study is published in Nature. (2020-01-16)

Treating sleep-disordered breathing may have cardiovascular benefits for heart failure patients
Severe sleep-disordered breathing is linked with stiffening of the arteries' walls and may be related to the development of heart failure, according to a recent study in ESC Heart Failure, a journal of the European Society of Cardiology. (2018-02-21)

Gene signature may improve colon cancer treatment
A gene signature, first identified in mouse colon cancer cells, may help identify patients at risk of colon cancer recurrence, according to a recent study by Vanderbilt-Ingram Cancer Center researchers. The findings, published in the March issue of Gastroenterology, could help personalize treatments for colon cancer -- the second leading cause of cancer-related deaths in the United States -- by identifying patients most likely to benefit from chemotherapy. (2010-02-26)

Young breast cancer patients undergoing breast conserving surgery see improved prognosis
A new analysis indicates that breast cancer prognoses have improved over time in young women treated with breast conserving surgery. (2017-08-09)

All young women with breast cancer should receive chemotherapy
All young women under the age of 35 years with breast cancer should be regarded as high risk patients and be offered chemotherapy after surgery (adjuvant cytotoxic treatment), say researchers from Denmark in this week's BMJ. (2000-02-17)

A genetic polymorphism associated with lung cancer progression
Researchers at the Hiroshima University and Saitama Medical University found that in patients with lung cancer, a single nucleotide polymorphism may regulate gene and protein expression and be associated with poor prognosis. To establish this genetic polymorphism as a useful clinical prognostic marker and to further clarify its molecular mechanism, large-scale clinicopathological studies of lung cancer and/or other types of cancer are required for additional insights. (2015-10-05)

DNR orders often do not align with poor prognosis
Although do-not-resuscitate (DNR) orders after in-hospital cardiac arrest were generally aligned with patients' likelihood of favorable neurological survival, almost two-thirds of patients with the worst prognosis did not have DNR orders, according to a study in the Sept. 22/29 issue of JAMA. (2015-09-22)

Breast cancer risk, prognosis and weight gain reduced with physical activity
Designing physical activity programs and interventions geared to breast cancer survivors will increase well-being and may improve prognosis, Yale researchers report in a recent issue of Medicine and Science in Sports and Exercise. (2004-10-29)

Pacemaker for slow heart rhythm restores life expectancy
The FollowPace study provides detailed documentation of current standard pacemaker care in a large representative sample of western pacemaker clinics. The results can therefore be considered a new benchmark of life expectancy of patients treated with today's cardiac pacing. (2013-09-02)

The importance of the glutamine metabolism in colon cancer
The importance of glutamine was made clear as a colon cancer specific metabolism. It is known that glutamine metabolism is important for pancreatic cancer, but the importance of glutamine metabolism for colon cancer has been unclear. In this study, we showed the importance of glutamine metabolism. (2017-01-10)

Rare mutations in bowel cancer may identify patients with a better prognosis
A study focused on colorectal cancers and examined the presence of mutations in a gene that is essential for the accurate copying of DNA when cells divide, known as DNA polymerase epsilon (POLE). As a consequence of the defects in copying their DNA, these tumors accumulate a much higher number of additional mutations than other bowel cancers -- a characteristic that may explain an apparently enhanced immune response against them. (2016-07-19)

Mayo Clinic researchers confirm value of therapeutic hypothermia after cardiac arrest
Mayo Clinic researchers confirmed that patients who receive therapeutic hypothermia after resuscitation from cardiac arrest have favorable chances of surviving the event and recovering good functional status. In therapeutic hypothermia, a patient's body temperature is cooled to 33 degrees Celsius following resuscitation from cardiac arrest, in order to slow the brain's metabolism and protect the brain against the damage initiated by the lack of blood flow and oxygenation. This study was published in the December 2010 issue of Annals of Neurology. (2011-02-18)

30 years later, epilepsy surgery shows good results
A new study shows that the prognosis is good for people who have epilepsy surgery, even 30 years after the surgery. The study is published in the June 14 issue of Neurology, the scientific journal of the American Academy of Neurology. (2005-06-13)

Rehabilitation improves the prognosis of serious heart disease
Rehabilitation is recommended for many patients following a hospital stay for acute heart disease. In a recent original article in Deutsches Ă„rzteblatt International, Axel Schlitt et al. show that this improves prognosis for heart disease and can thus reduce patient mortality. (2015-08-26)

Does treatment of depression improve prognosis after heart attack?
Depression and heart disease are the two leading disorders with the strongest contributions to the global burden of disease. Depression and heart disease are also intertwined. (2008-09-01)

Immune system important in fight against stomach cancer
Researchers have identified cells in the immune system that react to the stomach ulcer bacterium Helicobacter pylori, one of the risk factors for the development of stomach cancer. This discovery could lead to faster diagnosis and treatment as well as a better prognosis for patients with stomach cancer, reveals a thesis from the University of Gothenburg, Sweden. (2010-06-28)

Many good years after heart bypass surgery -- but something happens after 10 years
The prognosis following heart bypass surgery is both good and has improved over the past three decades. In fact, the survival rate for bypass patients who make it through the first month after the operation is close to that of the population in general. But 8-10 years after a heart bypass operation, mortality increases by 60-80 percent. This is new and important knowledge for the doctors who monitor these patients. (2017-06-07)

Test accurately predicts aggressiveness of breast cancer
A test that measures how quickly cells are dividing is an accurate way for doctors to predict the aggressiveness of breast cancer tumors, even among women with very early stages of the disease, researchers told the 2nd ESMO Scientific & Educational Conference (ESEC) in Budapest, Hungary today. The findings will help clinicians decide which patients will benefit most from treatment with more intensive chemotherapy. (2005-06-06)

Therapy response in brain tumor cells is linked to disease prognosis
The brain tumor form glioblastoma is difficult to treat and has very poor prognosis. In a new study, published today in the journal Cell Reports, scientists from Uppsala University show that a type of stem cell in the tumor is present in different states, with different response to drugs and radiation. The results may open an avenue towards development of new treatment strategies designed to reverse therapy resistant cell states to more sensitive states. (2016-12-13)

Physicians' experiences with family and friends impact breast cancer screening
Results of a national survey of more than 800 physicians suggest that their experiences with patients, family members and friends with breast cancer are linked with their recommendations for routine mammograms. (2017-12-04)

Estrogen reduces aggression in breast cancer
A team of researchers at CIC bioGUNE has revealed that estrogen can reduce the risk of breast cancer. Their work shows that estrogen is capable of reducing the number of breast cancer stem cells, which may explain the lower aggression of the tumor and, as a consequence, the possibility of a better prognosis. The project was published in Breast Cancer Research and Treatment. The research combined the use of human samples and laboratory cell lines. (2011-02-14)

UAlberta medical researchers find DNA marker that predicts breast cancer recurrence
Medical researchers at the University of Alberta tested the DNA of more than 300 women in Alberta and discovered a 'genetic marker' method to help accurately profile which women were more apt to have their breast cancer return years later. (2013-01-16)

Expression of SIP1 protein indicates poor prognosis in pharyngeal cancer
The expression of SIP1 protein in pharyngeal squamous cell carcinoma tumours often indicates an advanced tumour stage, a high risk of recurrence and a poor prognosis, according to research from the University of Eastern Finland. Based on the results, SIP1 is a potential new prognostic factor for clinical use, helping to single out patients with more aggressive tumor behavior requiring more intensive therapy and closer follow-up. (2014-11-14)

A key to unlocking the mystery of triple negative breast cancer
The study suggests screening breast cancer patients for the prolactin receptor could improve the prognosis for patient and may help them avoid unnecessary and invasive treatments. The researchers found that prolactin hormone was able to reduce the aggressive behavior of cancerous cells. It does so by decreasing their ability to divide and form new tumors. (2016-10-24)

Revised glioblastoma classification should improve patient care
Radiation oncology researchers have revised the system used by doctors since the 1990s to determine the prognosis of people with glioblastoma, the most devastating of brain tumors. The outdated system was devised for brain tumors treated by radiation therapy only, and it relied on clinical signs and symptoms. The new system accommodates advances in treatment, and it incorporates molecular biomarkers as well as clinical variables. (2012-05-16)

Aggressive form of leukemia linked to defective 'protein factory'
20 to 40 percent of the patients with multiple myeloma -- a type of leukemia -- have a defect in the ribosome, the protein factory of the cell. These patients have a poorer prognosis than patients with intact ribosomes. At the same time, they respond better to a drug that already exists. These are the findings of a study by the Laboratory for Disease Mechanisms in Cancer at KU Leuven (University of Leuven), Belgium. (2016-12-09)

'Triple negative' breast cancers linked to the young, minority
A new study suggests that triple negative tumors are more common among women who are African-American and Hispanic, under 40 years old, and who have lower socioeconomic status (SES). The study found triple negative tumors are also associated with later diagnosis and shorter survival. (2007-03-26)

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