Prostate Cancer Current Events

Prostate Cancer Current Events, Prostate Cancer News Articles.
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Are men with a family history of prostate cancer eligible for active surveillance?
Active surveillance -- careful monitoring to determine if or when a cancer warrants treatment -- is an increasingly prevalent choice for prostate cancer, but it's unclear if the strategy is appropriate for men with a family history of prostate cancer. A recent analysis of the medical literature concluded that a family history of prostate cancer does not appear to increase a patient's risk of having more aggressive prostate cancer. (2017-04-06)

ALS drug may help treat prostate cancer
Researchers have discovered a new use for an old drug as a potential treatment for prostate cancer. The findings are published in the journal The Prostate. (2018-10-03)

Past and present of imaging modalities used for prostate cancer diagnosis
This review illustrates a perspective on prostate cancer imaging summarizing current imaging approaches with a special focus on Prostate Specific Membrane Antigen (PSMA), Bombesin (BN) and Androgen Receptor (AR) targeted imaging using Positron Emission Tomography (PET) and Single Positron Emission Computed Tomography (SPECT) based on 99mTc and other radiotracers. (2018-12-24)

Guilt by association: Scientists nab suspects in prostate cancer
Prostate cancer kills 40,000 American men annually, but blood tests for the disease are less than 100% reliable. In the December issue of Genome Research, Michael Walker (Incyte Pharmaceuticals and Stanford University), Tod Klinger (Incyte), and colleagues take a step towards better diagnosis and treatment of prostate cancer with the identification of eight new disease-associated genes. (1999-12-27)

Surgery unnecessary for many prostate cancer patients
Otherwise healthy men with advanced prostate cancer may benefit greatly from surgery, but many with this diagnosis have no need for it. These conclusions were reached by researchers after following a large group of Scandinavian men with prostate cancer for 29 years. The results are now published in The New England Journal of Medicine. (2018-12-12)

A roadmap for prostate cancer treatment
In this issue of the Canadian Medical Association Journal, Dr. Steven Grover and colleagues describe the Montreal Prostate Cancer Model they developed to follow a hypothetical cohort of men to estimate the probability of prostate cancer and the annual progression of the disease according to patient age, tumour stage and grade, and initial treatment. (2000-04-03)

Prostate cancer clinical stage does not predict recurrence
A new study challenges the current staging system that determines the extent or severity of prostate cancer that has not metastasized. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study found that there is no link between localized prostate cancer's clinical stage and a patient's risk of cancer recurrence after having his prostate removed. (2010-11-22)

Androgen receptor targeted imaging of prostate cancer as future modality for diagnosis
Future direction in prostate cancer imaging involves the development of androgen receptor based imaging using nonsteroidal antiandrogen agent for early diagnosis of prostate cancer. (2017-10-06)

Blocking signaling protein prevents prostate cancer spread, Jefferson scientists find
Researchers at the Kimmel Cancer Center at Jefferson in Philadelphia have shown that by blocking a signaling protein, they can prevent prostate cancer cells from metastasizing. In a series of experiments in both the laboratory and animal models, they found that the protein, Stat3, is key to the metastatic progression of prostate cancer. The work opens the door to studies examining the protein as a target for therapies to keep prostate cancer at bay. (2008-05-31)

Dietary isoflavones linked to increased risk of advanced prostate cancer
Dietary intake of isoflavones was linked with an elevated risk of advanced prostate cancer in a recent International Journal of Cancer study. (2017-11-08)

Study provides insights on statins' link to lower prostate cancer risk
In a Cancer Medicine study of cancer-free men followed for a median of seven years, statin use was associated with a lower risk of developing prostate cancer. (2019-10-09)

Prostate cancer series
A four-week series about prostate cancer-the third most common cancer in men worldwide, and the leading male cancer in Europe and North America-begins in this week's issue of The Lancet. (2003-03-06)

Greater height associated with increased risk of prostate cancer over age 50
Greater height appeared to be positively associated with subsequent risk of prostate cancer in men over age 50, according to a study presented at the national meeting of the American College of Preventive Medicine in San Diego. (2003-02-21)

Evidence of PSA screening efficacy lacking
There is no evidence to support speculation that prostate-specific antigen (PSA) screening has contributed to a decline in prostate cancer mortality rates since 1995, a new study has determined. The value of such screening remains controversial. (2002-03-04)

Eating mushrooms may help lower prostate cancer risk
A new study published in the International Journal of Cancer found an inverse relationship between mushroom consumption and the development of prostate cancer among middle-aged and elderly Japanese men, suggesting that regular mushroom intake might help to prevent prostate cancer. (2019-09-05)

Researchers confirm genetic alteration that triggers prostate cancer in mice and man
A team of researchers at Fred Hutchinson Cancer Research Center has confirmed that a molecular change found in human prostate cancers triggers the growth of prostate cancer in mice and in human cell lines. (2008-01-28)

Circumcision may help protect against prostate cancer
A new analysis led by researchers at Fred Hutchinson Cancer Research Center has found that circumcision before a male's first sexual intercourse may help protect against prostate cancer. Published early online in Cancer, a peer-reviewed journal of the American Cancer Society, the study suggests that circumcision can hinder infection and inflammation that may lead to this malignancy. (2012-03-12)

Marker for aggressive prostate cancer doubles up as a drug target
Researchers have discovered that a marker found on aggressive prostate cancer cells could also be used as a way to guide treatments to the cancer. (2016-11-08)

African-American men understimate risk of prostate cancer
Many African-American men radically underestimate the likelihood that having a needle biopsy for suspected prostate cancer will result in a cancer diagnosis, according to a study from the University of Chicago Medical Center. (2007-06-04)

Prostate cancer patients with highest risk of progression
Based on a large study of prostate cancer patients, researchers are finding that maintaining a normal body mass index, frequent physical activity and screening before diagnosis appear to be important in stopping prostate cancer from progressing. (2003-04-08)

Familiar history is an important factor for prostate cancer
For the first time, researchers at Umeå University and Lund University have estimated the risk of developing various types of prostate cancer for men with the disease in the family. Men with brothers who have had prostate cancer run twice as high a risk of being diagnosed themselves in comparison to the general population. This according to a study published in the Journal of the National Cancer Institute. (2016-07-11)

Study finds diet did not affect PSA levels
A new study conducted by researchers at Memorial Sloan-Kettering Cancer Center, the National Cancer Institute, and other centers found that over a four-year period, a low-fat, high-fiber diet had no impact on PSA levels in men without prostate cancer. In addition, the diet did not affect the incidence of prostate cancer in this group of 1,350 men. (2002-08-29)

New findings concerning hereditary prostate cancer
For the first time ever, researchers have differentiated the risks of developing indolent or aggressive prostate cancer in men with a family history of the disease. Researchers from the Swedish universities of Lund, Uppsala and Umeå now present new and somewhat surprising results. (2016-07-11)

Clinical trial at GHSU Cancer Center targets advanced prostate cancer
Select patients with advanced prostate cancer may benefit from a GHSU Cancer Center clinical trial that looks to improve survival rates of the FDA-approved prostate cancer drug Provenge. The trial, led by GHSU Cancer Center Director Samir N. Khleif, is the first in the country to investigate prostate cancer treatment combining Provenge with two other cancer-fighting drugs, CT-011 and cyclophosphamide. (2012-12-03)

New genetic discovery advances understanding of prostate cancer
A new and important genetic discovery, which sheds light on how prostate cancers develop and spread, has been made by an international research team led by scientists at The University of Nottingham. (2015-10-26)

New research model of human prostate cancer shows cancer development
Progress toward understanding the role of sex hormones in the growth of prostate cancer -- the most common cancer in US men -- has been hindered by the lack of a suitable laboratory research model. Now researchers say they have developed the first model of hormone-induced human prostate cancer initiation and progression. (2010-07-01)

Study links acetaminophen to lower prostate cancer risk
A new study from American Cancer Society researchers finds use of 30 tablets a month or more of acetaminophen for five or more years was associated with an estimated 38 percent lower risk of prostate cancer. (2011-05-23)

A dual imaging approach may improve diagnosis and monitoring of prostate cancer
A new platform that combines two established imaging methods can peer into both the structure and molecular makeup of the prostate in men with prostate cancer. (2019-08-28)

Gene mutations found that lead to prostate cancer in mice new mouse model developed to study the disease
Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) report in the February issue of Nature Genetics that inactivation of just one copy of a gene called PTEN and both copies of a gene called p27 leads to prostate cancer in mice 100 percent of the time. (2001-01-30)

Single gene drives prostate differentiation
Expression of a single gene can convert cells lining the seminal vesicle in the pelvis into prostate cells, a new study shows. (2016-06-23)

MEK4, genistein and invasion of human prostate cancer cells
Researchers have identified MEK4 as a pro-invasion protein and the target for genistein, a dietary compound, in prostate cancer cells, according to a new study published online July 28 in the Journal of the National Cancer Institute. (2009-07-28)

$1.6 million grant will use nanotechnology to fight prostate cancer
Nanotechnology for diagnosing and treating prostate cancer will be the focus of a five-year, $1.58 million grant by the National Institutes of Health to Penn State and the University of Texas Southwestern Medical Center. (2014-01-16)

Proepithelin encourages cell growth and migration in prostate cancer
Researchers from Thomas Jefferson University have identified a protein that appears to play a significant role in the growth and migration of prostate cancer cells, especially androgen-independent prostate cancer cells. (2009-02-26)

Exercise linked with reduced prostate cancer risk in Caucasians but not African-Americans
A new study suggests that exercise may reduce Caucasian men's risk of developing prostate cancer. And among Caucasian men who do have prostate cancer, exercise may reduce their risk of having more serious forms of the disease. Unfortunately, the benefits do not seem to apply to African-American men. (2013-02-11)

MR imaging helps predict recurrence in prostate cancer patients
MR images taken of prostate cancer patients prior to treatment that show that the cancer has spread outside the prostate gland capsule help predict whether the cancer will return, according to a recent study conducted by radiologists at the University of California-San Francisco. (2007-05-04)

Fatherhood linked to prostate cancer risk
A new study from Danish researchers has found that childless men have a lower risk of developing prostate cancer than fathers, and that, paradoxically, the more children a father has, the lower the risk of the disease. (2008-01-07)

Research aims to improve effectiveness of radiotherapy treatment for prostate cancer
A new three year research project aimed at improving the effectiveness of radiotherapy treatment for men affected by prostate cancer is taking place at Queen's. (2012-01-30)

Finally: A missing link between vitamin D and prostate cancer
A University of Colorado Cancer Center study recently published in the journal Prostate offers compelling evidence that inflammation may be the link between vitamin D and prostate cancer. Specifically, the study shows that the gene GDF-15, known to be upregulated by vitamin D, is notably absent in samples of human prostate cancer driven by inflammation. (2014-10-22)

Particular DNA changes linked with prostate cancer development and lethality
A new analysis has found that the loss or amplification of particular DNA regions contributes to the development of prostate cancer, and that patients with two of these DNA changes have a high likelihood of dying from the disease. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the study provides valuable information on the genetics of prostate cancer and offers insights into which patients should be treated aggressively. (2013-04-22)

Brachytherapy and early prostate cancer
The Genitourinary Cancer Disease Site Group of the Cancer Care Ontario Practice Guidelines Initiative has conducted a systematic overview of the literature to assess the role of brachytherapy in early prostate cancer. (2001-04-02)

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