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Psoriasis Current Events, Psoriasis News Articles.
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A new strategy for treating psoriasis
Dexamethasone and other steroids used for treating psoriatic skin inflammation probably act in part by inducing I-kB, thus preventing NF-kB from reaching the nucleus and trans-activating its many target genes, including those involved in T cell-dependent inflammation. Zollner and colleagues now propose a different means to this same end: Since the proteasome is responsible for the regulated turnover of I-kB, proteasome inhibitors might also alleviate psoriasis by blocking NF-kB activation. (2002-02-27)

Weight loss reduces psoriasis symptoms
Weight loss has a significant and prolonged positive impact on psoriasis symptoms and quality of life. The findings stem from a study conducted by Herlev and Gentofte Hospital, in collaboration with the University of Copenhagen's Department of Nutrition, Exercise and Sports and other participants. The results are published in The American Journal of Clinical Nutrition, an internationally renowned scientific journal. (2016-12-22)

Largest psoriasis meta-analysis to date yields new genetic clues
The identification of 16 additional genetic markers will help researchers get closer to understanding how -- and why -- psoriasis develops. (2017-05-24)

National Psoriasis Foundation awards 13 psoriasis research fellowships
Twelve residents and medical students each received a one-year, $50,000 National Psoriasis Foundation fellowship to study psoriasis. The fellowships aim to increase the number of scientists studying and treating psoriatic disease by encouraging promising doctors to dedicate their careers to the study of psoriasis as physician researchers. (2014-07-18)

Investigational study of ustekinumab in the treatment of psoriatic arthritis published
A group of patients suffering from potentially debilitating psoriatic arthritis showed significant and prolonged improvement after treatment with ustekinumab, according to data from a randomized, double-blind, placebo-controlled study in patients with moderate to severe psoriatic arthritis. The Phase 2 study was published in the British medical journal the Lancet. (2009-02-11)

National Psoriasis Foundation awards half a million dollars in fellowships
Eleven early-career physicians each received a one-year, $50,000 National Psoriasis Foundation Medical Dermatology Fellowship to study psoriasis and psoriatic arthritis. These fellowships will help increase the number of scientists studying and expertly treating psoriatic disease by encouraging up-and-coming doctors to dedicate their careers to these conditions. (2015-06-22)

New drug clears psoriasis in clinical trials
About 80 percent of patients with moderate to severe psoriasis saw their disease completely or almost completely cleared with a new drug called ixekizumab, according to three large, long-term clinical trials led by Northwestern Medicine. (2016-06-09)

Multiple factors affect psoriasis treatment compliance
Psychological, social, and disease-related issues may influence a patient's compliance with psoriasis treatment, according to an article in the April issue of The Archives of Dermatology, one of the JAMA/Archives journals. (2004-04-19)

Plaque psoriasis patients find many treatments, but few satisfied with their current plan
Psoriasis in America 2016, a new national survey by Health Union of nearly 600 individuals with psoriasis, reveals that although patients have numerous treatment options, they have difficulty finding treatment plans that work. In addition, respondents reported a heavy emotional toll, with many feeling isolated and stigmatized due to the condition. (2016-08-16)

Long-term etanercept treatment reduces psoriasis severity without increased adverse events
Extended exposure to the psoriasis medication etanercept does not appear to cause more infections or adverse events than placebo, and improvements in several measures of disease severity were observed for up to 96 weeks of therapy, according to a study in the June issue of Archives of Dermatology, one of the JAMA/Archives journals. (2007-06-18)

Wake Forest study shows women suffer from 'gender gap' in treatment of severe psoriasis
When it comes to the treatment of severe psoriasis, there is no equality between the sexes. Men have enjoyed the benefit of powerful drugs that address the disease, but women of childbearing age have gone without, according to dermatologists at the Westwood Squibb Center for Dermatology Research at Wake Forest University School of Medicine. (2000-04-02)

New antibody therapy dramatically improves psoriasis symptoms in clinical trial
By blocking an immune signaling protein known as interleukin-23 involved in this autoimmune disorder, this antibody treatment raises the possibility of sending psoriasis into long-term remission. (2015-03-13)

Increased risk of skin cancer for psoriasis patients given ciclosporin
The risk of squamous cell cancer of the skin is increased in patients treated for psoriasis with ciclosporin in addition to photochemotherapy, conclude authors of a study in this week's issue of THE LANCET. (2001-09-27)

Psoriasis: Light shed on new details
B lymphocytes, special cells of the immune system, play a major role in psoriasis. Scientists from Würzburg have made this discovery in a recent study. The cells might be a promising target for new therapy. (2016-06-08)

Psoriasis and psoriatic arthritis symptoms curbed by bariatric surgery
Psoriasis and psoriatic arthritis symptoms were significantly lessened in patients who underwent bariatric -- or weight loss -- surgery, according to researchers from NYU Langone Medical Center. According to the study's authors, the findings suggest that losing excess weight may improve symptoms in people who have these lifelong conditions. (2015-11-07)

Researchers identify 4 genetic hotspots associated with psoriasis
A genomewide scan of millions of genetic mutations has revealed four new DNA (2009-01-26)

Psoriasis associated with diabetes, BMI & obesity in Danish twin study
The chronic inflammatory skin disease psoriasis was associated with type 2 diabetes, body mass index and obesity in a study of Danish twins, and the study also suggests the possibility of a common genetic cause between psoriasis and obesity, according to an article published online by JAMA Dermatology. (2016-04-27)

Obesity in early adulthood associated with increased risk of psoriatic arthritis
Among persons with psoriasis, those who reported being obese at age 18 had an increased risk of developing psoriatic arthritis, according to a report in the July 19 issue of Archives of Dermatology, one of the JAMA/Archives journals. (2010-07-19)

National Psoriasis Foundation awards $1.05 million in research grants
Thirteen scientists received a total of $1.05 million in funding from the National Psoriasis Foundation for projects that aim to identify new treatments and a cure for psoriasis -- an autoimmune disease that appears on the skin, affecting 7.5 million Americans -- and psoriatic arthritis -- an inflammatory arthritis that affects the joints and tendons, occurring in up to 30 percent of people with psoriasis. (2014-07-16)

Severe psoriasis linked to major adverse cardiovascular events
New research from the University of Pennsylvania School of Medicine has revealed an increased incidence of major adverse cardiovascular events in patients with severe psoriasis. (2011-04-04)

New treatment for psoriasis is safe and effective
A new treatment for moderate to severe plaque psoriasis has proven safe and effective in a phase III trial. There is also an almost linear relationship between drug dose and response, suggesting that patients can be more accurately dosed to achieve a clinical response while minimizing the risk of side effects. These are the conclusions of authors of an article in this week's edition of the Lancet. (2008-04-17)

$1.8 million grant supports investigation of psoriasis link to cardiovascular disease
Armed with a new $1.8 million grant from the National Institute of Arthritis and Musculoskeletal and Skin Diseases, dermatology researcher Nicole Ward, PhD, assistant professor of dermatology and neurosciences at Case Western Reserve School of Medicine, will lead a study examining the link between psoriasis and heart attack and stroke. (2012-09-20)

Researchers uncover critical metabolic switch for inflammatory diseases
A research team in Trinity College Dublin has uncovered a critical role for a protein called 'PKM2' in the regulation of immune cell types at the heart of multiple inflammatory diseases. (2019-11-21)

How was Mediterranean diet associated with severity of psoriasis?
Adherence to a Mediterranean diet, an eating plan filled with fruits and vegetables, legumes, cereals, bread, fish, fruit, nuts and extra-virgin olive oil, may be associated with the severity of the skin condition psoriasis. (2018-07-25)

Small molecules may explain psoriasis
A research team at the Swedish medical university Karolinska Institutet has shown for the time that microRNA, small RNA molecules, may play an important role in the development of inflammatory skin diseases such as psoriasis and atopic eczema. The research team is led by Professor Mona Ståhle, one of Sweden's most prominent scientists in the field. (2007-07-11)

Severity of skin psoriasis linked to blood vessel inflammation, cardiovascular risk
The amount of psoriasis a person has on their skin may be related to the amount of inflammation in their blood vessels. Increased blood vessel inflammation may contribute to increased risk of heart attack and stroke. (2015-10-08)

Study finds long-term sustained effect of biological psoriasis treatment
Biological treatment of psoriasis shows a good efficacy in clinical trials. Since most analyses have focused on short-term outcomes of single biological agents, little has been known about long-term outcomes in clinical practice, where switching between biological agents is common. A Swedish study that followed 583 individuals for up to 10 years shows a satisfactory long-term effectiveness of biologic treatments. The findings were recently published in the British Journal of Dermatology. (2017-06-28)

Mayo researchers offer evidence people with psoriasis greater risk for developing heart disease
People with the skin disorder psoriasis are at increased risk for developing heart disease, according to Mayo Clinic researchers presenting new study data at the American College of Rheumatology Annual Meeting on November 14. (2006-11-11)

Psoriasis severity linked to rising risk of abdominal aortic aneurysms
Psoriasis sufferers may have an increased risk for abdominal aortic aneurysms. The more severe the psoriasis, the greater the risk of developing abdominal aortic aneurysms. Psoriasis should be considered an inflammatory state affecting the whole body, rather than an isolated skin disease. (2016-04-14)

Psoriasis onset determines if psoriatic arthritis patients develop arthritis or psoriasis first
In a new study presented at the 2019 ACR/ARP Annual Meeting, researchers found the age of psoriasis onset determines whether arthritis or psoriasis starts first in people with psoriatic arthritis. Additionally, they found that pustular psoriasis is associated with arthritis onset two years earlier than the intercept interval; and there is an increased delay for nail involvement, plaque psoriasis or family history of psoriasis from psoriasis to arthritis by approximately two years for each characteristic. (2019-11-09)

Costs of psoriasis treatments outpace inflation
Findings from a cost model suggest that expenses for systemic psoriasis therapy appear to be increasing at a faster rate than inflation, and newer biologically derived treatments are more expensive than traditional systemic therapies, according to a report in the January issue of Archives of Dermatology, one of the JAMA/Archives journals. (2010-01-18)

Case Western Reserve-led research uncovers connections between psoriasis and joint disease
A team led by Case Western Reserve University School of Medicine researchers has made two major discoveries involving psoriasis, a chronic and debilitating skin disease with no known cure. (2020-06-08)

Link between autoimmune, heart disease explained in mice
Autoimmune diseases such as psoriasis, lupus and rheumatoid arthritis more than double the risk of cardiovascular disease. A new study shows that immune cells that arise during autoimmune disease cause cholesterol to become trapped inside blood vessels. (2018-11-08)

Treating psoriasis to prevent heart attacks and strokes
A clinical study co-led by the Montreal Heart Institute and Innovaderm Research Inc., which was presented today at the annual meeting of the American Academy of Dermatology, shows that a new treatment for psoriasis could be associated with a significant decrease in vascular inflammation, a major risk factor of cardiovascular disease. (2012-03-16)

Scientists put psoriasis drugs to the test
Clinical trials to test the effectiveness of two prescription drugs for the debilitating skin condition psoriasis have revealed significant differences that should help inform physicians treating patients with the condition. (2010-01-13)

Penn researchers find psoriasis patients at increased risk for heart attack
Psoriasis is an independent risk factor for myocardial infarction, and this risk is greatest in young patients with severe psoriasis, according to Joel M. Gelfand, M.D., M.S.C.E., assistant professor of dermatology, University of Pennsylvania School of Medicine, and lead author of the study that appears in the Oct. 11 issue of JAMA. (2006-10-10)

Psoriasis patients face higher than average death risk after a heart attack
Heart attack patients with psoriasis are 26 percent more likely to die from cardiovascular disease, or suffer from recurrent heart attacks or strokes, and are 18 percent more likely to die from all causes than those without the inflammatory skin disease. Researchers studied nearly 50,000 patients who had experienced their first heart attack between 2002 and 2006, following the 462 patients with psoriasis for an average of 19.5 months and the 48,935 controls for an average of 22 months. (2011-09-12)

Home UVB therapy for psoriasis as effective and safe as hospital treatment
For patients with psoriasis, treatment with ultraviolet B at home is as effective and as safe as conventional hospital based phototherapy, concludes a study published on bmj.com today. (2009-05-07)

In hairless man, arthritis drug spurs hair growth -- lots
A man with almost no hair on his body has grown a full head of it after a novel treatment by doctors at Yale University. There is currently no cure or long-term treatment for alopecia universalis, the disease that left the 25-year-old patient bare of hair. This is the first reported case of a successful targeted treatment for the rare, highly visible disease. (2014-06-19)

Scientists unmask genetic markers associated with psoriasis
Scientists at the University of Michigan Department of Dermatology, the U-M School of Public Health and their collaborators have found DNA (2009-01-25)

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