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SARS Current Events, SARS News Articles.
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New method helps pocket-sized DNA sequencer achieve near-perfect accuracy 
Researchers have found a simple way to eliminate almost all sequencing errors produced by a widely used portable DNA sequencer (Oxford Nanopore Technologies' MinION device). (2021-01-12)

Study highlights risk of new SARS-CoV-2 mutations emerging during chronic infection
SARS-CoV-2 mutations similar to those in the B1.1.7 UK variant could arise in cases of chronic infection, where treatment over an extended period can provide the virus multiple opportunities to evolve, say scientists. (2021-02-05)

International Conference on Emerging Infectious Diseases
Journalists are invited to attend and cover the 2004 International Conference on Emerging Infectious Diseases (ICEID), to be held February 29 to March 3, 2004 at the Atlanta Marriott Marquis Hotel in Atlanta, Georgia. The meeting is being organized by the Centers for Disease Control and Prevention (CDC), the American Society for Microbiology, the Council of State and Territorial Epidemiologists, the Association of Public Health Laboratories and the World Health Organization. (2004-01-07)

Largest genetic analysis of MERS coronavirus to date suggests that virus has transmitted from animals to humans more than once
The largest study of Middle East respiratory syndrome coronavirus genomes to date, published in The Lancet today, reveals new information about how MERS-CoV is evolving, and its likely patterns of transmission. (2013-09-19)

App analyzes coronavirus genome on a smartphone
A team led by Garvan's Dr Ira Deveson developed the app 'Genopo' that can analyse the coronavirus genome on a portable Android device. (2020-09-29)

3D protein modeling suggests why COVID-19 infects some animals, but not others
Some animals are more susceptible to Covid-19 infection than others, and new research suggests this may be due to distinctive structural features of a protein found on the surface of animal cells. João Rodrigues of Stanford University, California, and colleagues present these findings in the open-access journal PLOS Computational Biology. (2020-12-03)

Up to 45 percent of SARS-CoV-2 infections may be asymptomatic
Asymptomatic infections may have played a significant role in the early and ongoing spread of COVID-19 and highlight the need for expansive testing and contact tracing to mitigate the pandemic. (2020-06-12)

An important new tool for developing COVID-19 treatments, vaccines
Scientists have a new resource to help them better understand COVID-19 as they develop treatments and vaccines. (2020-06-02)

T cells take the lead in controlling SARS-CoV-2 and reducing COVID-19 disease severity
A multi-layered, virus-specific immune response is important for controlling SARS-CoV-2 during the acute phase of the infection and reducing COVID-19 disease severity, with the bulk of the evidence pointing to a much bigger role for T cells than antibodies. A weak or uncoordinated immune response, on the other hand, predicts a poor disease outcome. (2020-09-16)

Scientists predict that COVID-19 will become a seasonal virus - but not yet
Researchers predict that COVID-19 will likely become seasonal, waning in the summer and prevalent in the winter. But, only once herd immunity is achieved through natural infection or vaccinations. Until then, COVID-19 will be here year-round. (2020-09-15)

Nanoparticle vaccine for COVID-19
Researchers at Stanford are working to develop a single-dose vaccine for SARS-CoV-2 that could potentially be stored at room temperature. (2021-01-08)

A roadmap for effective treatment of COVID-19
Researchers from the US Food and Drug Administration have reviewed the available scientific literature on COVID-19 and systematically outlined key immunological factors underlying COVID-19 disease severity. Based on these factors, the researchers indicate a range of approved and available drugs, as well as drugs currently under clinical investigation, as possible candidates for treatment. (2020-05-29)

Oral saline spray may slash spread of exhaled pathogens
Some individuals exhale many more pathogen-laden droplets than others in the course of ordinary breathing, scientists have found, but oral administration of a safe saline spray every six hours might slash exhalation of germs in this group by an average 72 percent. The work, by researchers at Harvard University and biotechnology firms Pulmatrix and Inamed, may help decrease the spread of bacteria and viruses responsible for airborne infectious diseases such as influenza, tuberculosis, and SARS. (2004-11-29)

Ultra clean transportation fuels by deep desulfurization
A process that removes organic sulfur from liquid fuels at low temperatures and ambient pressure without using hydrogen, may help refiners provide fuels for fuel cells and meet the upcoming government's ultra-clean fuel requirements, according to Penn State researchers. (2002-04-08)

Aging-associated inflammation may worsen COVID-19 outcomes in older individuals
The increased severity and mortality of SARS-CoV-2 infections in older individuals may be related to inflammageing -- an age-associated phenomenon of increased general inflammation. (2020-07-16)

After developing CRISPR test, UConn researchers validate clinical feasibility for COVID-19 testing
In March, researchers in the Department of Biomedical Engineering-- a shared department in the schools of Dental Medicine, Medicine, and Engineering--began to develop a new, low-cost, CRISPR-based diagnostic platform to detect infectious diseases, including HIV virus, the novel coronavirus (SARS-CoV-2). Today, the method is one step closer to being a cutting-edge diagnostics technology for rapid detection of infectious diseases. (2020-09-18)

Whole-town study reveals more than 40% of COVID-19 infections had no symptoms
A study of COVID-19 in the quarantined Italian town of Vò, where most of the population was tested, reveals the importance of asymptomatic cases. (2020-06-30)

JAMA Viewpoint: Middle East respiratory syndrome: A global health challenge
In a JAMA Viewpoint published online June 17, two Georgetown public health experts outline strategies for managing MERS-CoV, focusing on transparency, trust and infection control in health care settings. The duo also outlines weaknesses in a World Health Organization framework designed to govern patents on certain viruses, which is likely to impact critical future research. (2015-06-17)

Rapid EUnetHTA assessment on coronavirus diagnostics supported by IQWiG
Rapid EUnetHTA assessment on coronavirus diagnostics supported by IQWiG. Antibody tests can detect a past infection with SARS Corona virus. However, the test result is not sufficient to detect immunity or to exclude infectivity. (2020-06-25)

COVID-19 evidence and strategies for orthopaedic surgeons
How should orthopaedic surgeons respond to the COVID-19 pandemic? A review in The Journal of Bone & Joint Surgery analyzes evidence and strategies for managing the novel SARS-CoV-2 virus - including critical lessons from past pandemics. The journal is published in the Lippincott portfolio by Wolters Kluwer. (2020-05-21)

New antigen test for detecting COVID-19 could help triage patients during the pandemic
A new antigen test for detecting COVID-19 can return results within 15 minutes. Researchers who evaluated the assay, which was developed by a biotech company in Belgium, say it could help with patient diagnostics in areas hardest hit by the pandemic. While not as sensitive as tests that use viral RNA to detect the presence of an antigen, the COVID-19 Ag Respi-Strip test could be a useful tool in slowing the spread of the virus. (2020-05-08)

Scientists evaluated the perspectives of zinc intake for COVID-19 prevention
Researchers from Sechenov University in collaboration with colleagues from Germany, Greece and Russia reviewed scientific articles on the role of zinc in the prevention and treatment of viral infections and pneumonia, with projections on those caused by SARS-CoV-2. The results were published in the International Journal of Molecular Medicine. (2020-07-13)

TGen adds to international studies identifying cells susceptible to SARS-CoV-2 infection
Two studies involving hundreds of scientists, including a human geneticist at TGen, suggest that cells in the nasal passage shaped like champagne glasses -- goblet cells -- may play a significant role in the spread of COVID-19. One published April 23 in Nature Medicine and another published April 22 in Cell, indicate goblet cells highly express a receptor enzyme called ACE2 that binds to the spikes covering the outer surface of SARS-CoV-2, the virus that causes COVID-19. (2020-04-23)

The Lancet: Preliminary evidence suggests that new coronavirus cannot be passed from mother to child late in pregnancy
There is currently no evidence that the 2019 novel coronavirus disease (COVID-19) causes severe adverse outcomes in neonates or that it can pass to the child while in the womb, according to a small observational study of women from Wuhan, China, who were in the third trimester of pregnancy and had pneumonia caused by COVID-19. (2020-02-12)

The Lancet Infectious Diseases: Post-SARS, infection rates in China have steadied, but fast-growing and common infections now need attention
Following the severe acute respiratory syndrome (SARS) outbreak in 2003, China stepped up its prevention and control methods for all infectious diseases, and rates of infection have levelled off since 2009. However, better measures are needed to tackle the most common diseases -- including hand, foot and mouth disease, hepatitis B, and tuberculosis -- and those that are rapidly increasing, such as hydatid disease, hepatitis C, syphilis, and HIV. (2017-04-12)

Coronavirus mutations show early safety measures and restrictions limited viral spread
Scientists analyzed genomic information from over 6,000 samples of SARS-CoV-2, the coronavirus behind the COVID-19 pandemic. Results show that early measures in states such as California and Washington were effective at limiting viral spread in the early phases of the pandemic. (2020-10-22)

COVID19 A research of Politecnico di Milano discovering the secrets of viral sequences
Use of an algorithm for computing viral mutations homogeneously across sources, using cloud computing. (2020-11-23)

How upregulation of a single gene by SARS-CoV-2 can result in a cytokine storm
The SARS-CoV-19 virus initially has a limited capability to invade, attacking only one intracellular genetic target, the aryl hydrocarbon receptors (AhRs). Yet it leads to widely diverse clinical symptoms, suggesting multiple pathogenic mechanisms. Writing in Restorative Neurology and Neuroscience, investigators describe how excessive activation of AhRs via the IDO1-kynurenine-AhR signaling pathway leads to ''Systemic AhR Activation Syndrome'' (SAAS). The authors also hypothesize that therapies targeting downregulation of AhRs and IDO1 genes should decrease severity of infection. (2020-06-29)

Computer model shows how COVID-19 could lead to runaway inflammation
New study addresses a mystery first raised in March: Why do some people with COVID-19 develop severe inflammation? The research shows how the molecular structure and sequence of the SARS-CoV-2 spike protein could be behind life-threatening inflammatory conditions MIS-C and cytokine storm. (2020-09-29)

Study: Urban density not linked to higher coronavirus infection rates -- and is linked to lower COVID-19 death rates
A new study suggests that denser places, assumed by many to be more conducive to the spread of the coronavirus that causes COVID-19, are not linked to higher infection rates. (2020-06-18)

Frequent, fast, accessible testing should be public health tool during COVID-19 pandemic
In a perspective piece published in Science, Brigham and Women's Hospital's Michael Mina, MD, PhD, and his co-author, Kristian G. Andersen, PhD, describe the power of public health screening, which focuses on mitigating transmission of the virus at the population level, and how it may be a crucial and overlooked tool. (2020-12-21)

Unmasked and vulnerable
Donning a face mask is an easy way to boost protection from severe respiratory illnesses such as influenza and SARS, new research from the University of New South Wales has found, but convincing a reluctant public and health workers is proving a struggle. (2009-01-26)

New in Ethics and Human Research
Covid-19: Why Challenge Trials of Vaccines Could be Ethical, Despite Severe Risks, Equitably Sharing the Benefits and Burdens of Research. Early-view articles and the May-June 2020 issue. (2020-06-10)

Single-shot COVID-19 vaccine protects non-human primates
A leading COVID-19 vaccine candidate, developed at Beth Israel Deaconess Medical Center, creates the groundwork for a newly launched COVID-19 vaccine clinical trial. (2020-07-30)

How COVID-19 affects pediatric patients
New insights into the clinical and epidemiological characteristics of pediatric patients with coronavirus disease 2019 (COVID-19) could facilitate early identification and intervention in suspected patients, according to a study publishing on June 16, 2020 in the open-access journal PLOS Medicine by Xihui Zhou of the First Affiliated Hospital of Xi'an Jiaotong University, China and colleagues. (2020-06-16)

Surgical masks and N95 respirators provide similar protection against influenza
A McMaster University study has found that surgical masks appear to be as good as N95 respirators in protecting health-care workers against influenza. (2009-10-01)

Bats are the major reservoir of coronaviruses worldwide
Results of a five-year study in 20 countries on three continents have found that bats harbor a large diversity of coronaviruses (CoV), the family of viruses that cause severe acute respiratory syndrome coronavirus (SARS) and Middle East respiratory syndrome coronavirus (MERS). PREDICT is a USAID-funded globally coordinated effort to detect and discover viruses of pandemic potential and reduce risk for future epidemics. (2017-06-12)

Statins reduce COVID-19 severity, likely by removing cholesterol that virus uses to infect
Analyzing anonymized patient medical records, UC San Diego researchers discovered that cholesterol-lowering statins reduced risk of severe COVID-19 infection, while lab experiments uncovered a cellular mechanism that helps explain why. (2020-09-23)

Neutralizing antibodies protect against severe COVID-19
Scientists at the Ragon Institute of MGH, MIT and Harvard, publishing in the journal Cell, show that the potency of neutralizing antibodies which developed in COVID-19 patients was significantly reduced in those with severe or fatal disease compared to patients with milder infections. (2020-12-16)

COVID-19 causes 'hyperactivity' in blood-clotting cells
Changes in blood platelets triggered by COVID-19 could contribute to the onset of heart attacks, strokes, and other serious complications in some patients who have the disease, according to University of Utah Health scientists. The researchers found that inflammatory proteins produced during infection significantly alter the function of platelets, making them ''hyperactive'' and more prone to form dangerous and potentially deadly blood clots. (2020-06-30)

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