Salicylic Acid Current Events

Salicylic Acid Current Events, Salicylic Acid News Articles.
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Evidence for warts treatments is weak
Apart from topical treatments containing salicylic acid, there is currently no clear evidence that any other treatments for warts are more effective, say researchers in this week's BMJ. (2002-08-29)

Liquid nitrogen most effective at removing warts
Cryotherapy with liquid nitrogen is the most effective method to remove common warts, found a study published in CMAJ. (2010-09-13)

How plants synthesize salicylic acid
The pain-relieving effect of salicylic acid has been known for thousands of years. Besides being a useful drug with numerous health applications, it is a stress hormone made by plants, which is essential for them to fight off damaging pathogens. What was not known, is how plants generated this hormone. Now, an international research team led by the University of Göttingen has unravelled the biosynthesis of this crucial hormone. The results were published in Science. (2019-08-13)

Bloom preservation
If you want your cut gerberas to last longer in the vase, you could try a flower food made from acids and urea. That's the conclusion of research published in the International Journal of Postharvest Technology and Innovation. (2015-05-19)

Ancient anti-inflammatory drug salicylic acid has cancer-fighting properties
Scientists from the Gladstone Institutes have identified a new pathway by which salicylic acid -- a key compound in the nonsteroidal anti-inflammatory drugs aspirin and diflunisal -- stops inflammation and tumor growth in cancer. Both salicylic acid and diflunisal suppress two key proteins that help control gene expression throughout the body. By inhibiting these proteins, the two drugs block the activation of other proteins involved in inflammation and cell growth, including one linked to leukemia. (2016-05-31)

Aspirin targets key protein in neurodegenerative diseases
The active ingredient in aspirin blocks an enzyme that triggers cell death in several neurodegenerative diseases. More potent forms of salicylic aspirin exist, which may provide treatments for these diseases. (2015-11-30)

Leaf hormone blocks bacteria from the roots
A defensive plant hormone located in the leaves helps to sculpt the microbiome, or community of microorganisms, surrounding a plant's roots, researchers say. (2015-07-16)

Aspirin could reduce the risk of deadly infections
Adding to the long list of the benefits of aspirin, researchers have found that it is responsible for reducing toxic bacteria associated with serious infections. A study led by Dartmouth Medical School describes how salicylic acid-produced when the body breaks down aspirin-disrupts the bacteria's ability to adhere to host tissue, reducing the threat of deadly infections. (2003-07-17)

New study provides key insights into aspirin's disease-fighting abilities
Researchers at Boyce Thompson Institute have found a new explanation for how aspirin works in the body to reduce the risk of heart disease and certain cancers. Aspirin's active form, salicylic acid, blocks a protein called HMGB1, which triggers inflammation in damaged tissues. The new findings may explain the disease-preventing effects of a low-dose aspirin regimen and offer hope that more effective aspirin-like drugs may be developed for a wide variety of diseases. (2015-10-09)

Single enzyme controls 2 plant hormones
Scientists at Washington University in St. Louis have isolated the first enzyme shown to be capable of controlling the levels of two distinct plant hormones, involved both in normal growth and in responses to infections. Overexpressing the protein in plants reduced the levels of active hormones, leading to stunted plants. The researchers purified the protein and solved the structure, showing surprising similarities with enzymes that could only bind a single hormone. (2016-11-22)

German-Argentinean doctoral program bears first fruits
The Faculty of Biology at TU Dresden and the Faculty of Biochemistry and Biological Sciences at the Universidad Nacional del Litoral (UNL) in Santa Fe, Argentina have had a very special partnership for more than five years. A bi-national doctoral program not only enables doctoral students from both research institutions to spend a longer period of time abroad, but also offers a double degree in Biochemistry and Applied Biology. (2020-08-14)

Defenses up: Hormone helps plants determine friend from foe
According to new research from Howard Hughes Medical Institute scientists, the defense hormone salicylic acid helps select which bacteria live both inside and on the surface of a plant's roots, keeping some bacteria out and actively recruiting others. (2015-07-16)

Ionic and covalent drug delivery
Researchers at Zelinsky Institute of Organic Chemistry, Russian Academy of Sciences compared three different drug delivery models based on ionic liquids. Scientists have developed a powerful API-IL concept to access structural diversity and dual-action pharmaceuticals. The study, published in ACS Medicinal Chemistry Letters, introduces new possibilities for application of drug delivery concept using ionic and covalent molecular level forces. (2015-10-07)

Salicylic acid promotes nasal mucosa colonization
An international research team, including scientists from Vetmeduni Vienna, has now shown that this multifaceted compound can also have an unpleasant side effect. Salicylic acid forms complexes with iron and lab tests showed that the iron limitation strongly promotes formation of biofilms by Staphylococcus aureus. This allows the bacteria to survive and persist in our respiratory tract for longer periods of time which eventually trigger life-threatening infections in immunocompromised persons. Published in Frontiers in Microbiology. (2017-02-03)

Plant signals travel different routes to turn on defense
Faced with a pathogen, important signaling chemicals within plant cells travel different routes to inform the plant to turn on its defense mechanisms, according to a recent University of Kentucky study. (2016-04-21)

Plants on aspirin
For centuries humans were using willow barks to treat a headache or an inflamed tooth. Later, the active ingredient, the plant hormone salicylic acid, was used to develop painkillers like Aspirin. But what happens, if plants are treated with these painkillers? By doing so, Scientists at the Institute of Science and Technology (IST) Austria discovered an unexpected bioactivity of human pharmaceuticals in plants. The scientists published their study in the journal Cell Reports. (2020-12-01)

Nodulation connected to higher resistance against powdery mildew in legumes
Scientists have long known that nodulation is important to plant health. Nodulation occurs when nodules, which form on the roots of plants (primarily legumes), form a symbiotic relationship with nitrogen-fixing bacteria that deliver nutrients to the plant. This process is a key part of sustainable agriculture and makes legumes an important source of protein for much of the world. However, recent research shows that nodulation might positively impact the plant's microbiome in other ways. (2019-10-07)

Thale cress goes on the defensive
Thale cress has a complicated defence technique against insects and microorganisms that use the plant as a source of food. The plant hormone jasmonic acid plays a major role during the immune response against insects and pathogens. Dutch researcher Vivian van Oosten has demonstrated that this does not necessarily lead to the control of the same genes during the various interactions. (2007-05-14)

Thirsty seeds reach for medicine cabinet
Scientists have found that salicylic acid -- also used to make aspirin -- can help the cowpea be more drought tolerant. In Brazil, the cowpea one of the main sources of protein for many people. Americans may know the cowpea by the name black-eyed pea. (2017-05-10)

Defenseless plants arm themselves with metals
A group of plants that uses metal to defend against infection may do so because the normal defense mechanism used by most other plants is blocked. Purdue University researchers found that this group of plants produces, but does not respond to, the molecule that triggers the infection response used by nearly all other plants. The molecule does, however, allow this group of plants, called metal hyperaccumulators, to store high levels of metal in their tissues, rendering them pathogen resistant. (2005-03-11)

Symposium to highlight regulation of plant immune responses
The Symposium: Signal Transduction Mechanisms in Plant Defense Activation will be held from 4 p.m. to 6 p.m. Tuesday, July 24, 2001 in Ballrooms A,D& E of the Rhode Island Convention Center as part of the annual meeting of the American Society of Plant Biologists (ASPB). (2001-07-17)

Using wastewater to enhance mint production
Researchers have discovered that residual distillation water of some aromatic plant species has a beneficial effect on yield and can increase essential oil content in mint crops. A study of the effects of three plant hormones and residual distillation water from 15 plant species applied as foliar sprays on biomass yields, essential oil content, and essential oil yield of peppermint and spearmint could result in economic and environmental benefits for large-scale production operations. (2011-03-03)

The balancing act between plant growth and defense
Kumamoto University researchers have pinpointed the mechanism that regulates the balance between plant growth and defense. Excessive accumulation of hormones that protect against pathogen infection significantly hinders plant growth. Researchers found that the DEL1 gene plays a role in balancing growth and defense of plants infected with nematodes. This finding is expected to contribute to the improvement of agricultural crop varieties and the identification of infection mechanisms of various pathogens. (2020-06-16)

Damage-signalling protein shows parallels between plant and human immune systems
Professor Daniel Klessig and colleagues at the Boyce Thompson Institute have identified a novel 'DAMP' molecule in plants that triggers an immune response after tissue damage. Knowledge of this protein and its human equivalent give us a cross-kingdom understanding of how humans and plants fight off infections. (2016-03-24)

New evidence that people make aspirin's active principle -- salicylic acid
Scientists in the United Kingdom are reporting evidence that humans can make their own salicylic acid -- the material formed when aspirin breaks down in the body. Salicylic acid, which is responsible for aspirin's renowned effects in relieving pain and inflammation, may be the first in a new class of bioregulators, according to a study scheduled for the Dec. 24 issue of ACS' biweekly Journal of Agricultural and Food Chemistry. (2008-12-22)

An aspirin a day keeps Staphylococcus aureus away
In the July 15 issue of The Journal of Clinical Investigation, Ambrose Cheung and colleagues at Dartmouth School of Medicine in New Hampshire, USA, report that salicylic acid (SAL), the major metabolite of aspirin, downregulates two Staphylococcus aureus genes key to this organism's pathogenesis. The report is the first description of aspirin-mediated genetic effects against S. aureus and represents an exciting new prospect for this widely used and established drug. (2003-07-15)

Bacterium signals plant to open up and let friends in
Researchers have identified the set of tools an infectious microbe uses to persuade a plant to open the windows and let the bug and all of its friends inside. (2012-06-13)

Study finds new relationship between gene duplication and alternative splicing in plants
University of Georgia scientists looking to understand the genetic mechanisms of plant defense and growth have found for the first time in plants an inverse relationship between gene duplication and alternative splicing. The finding has implications for diversity not only in plants, but in animals and humans. (2009-12-07)

Recycling plastic: Vinyl polymer broken down to aspirin components
Not a day goes by without news of microplastics in our oceans. There are not many efficient methods of recycling plastics without compromising quality. A beacon of hope was recently lit at Shinshu University where researchers discovered acid hydrolysis of a vinyl polymer breaks down into salicylic acid and acetic acid, precursors to dehydroaspirin which in theory can be made into vinyl polymers again. (2019-07-01)

Researchers unravel role of priming in plant immunity
Scientists have discovered a naturally occurring compound that triggers a plant's immune system, protecting it from infection. The patent-pending discovery could lead to an effective, inexpensive and environmentally safe way to improve plants' resistance to disease. Although it has long been known that plants have immune systems, how they has been studied intensely. This study discovered crucial steps and compounds involved in the immune system of a plant related to cabbage, broccoli and cauliflower. (2009-04-02)

ACSL1 as a main catalyst of CoA conjugation of propionic acid-class NSAIDs in liver
Researchers from Kanazawa University have found that propionic acid-class nonsteroidal anti-inflammatory drugs (NSAIDs), including ibuprofen, form ''conjugates'' with coenzyme A (CoA) by one of the acyl-CoA synthetases, ACSL1, in liver. These conjugates have the covalent binding ability to cellular proteins that may lead to liver injury, a rare severe side effect of NSAID treatment. This knowledge could help pharmaceutical companies to generate pain control options with fewer risks of severe side effects. (2021-01-22)

Plant immune system's 'take two aspirin' gene, offers hope for disease control
Plant immune systems' (2003-12-08)

Drugs made from polymers, the stuff of plastics
A potentially safer, more potent form of aspirin -- made from the same polymers that are the stuff of plastics -- was described at the 220th national meeting of the American Chemical Society. It this is believed to be the first time that a polymer has been used as a drug itself. (2000-08-22)

UMBC research decodes plant defense system, with an eye on improving farming and medicine
The plant circadian clock determines when certain defense responses are activated (often timed with peak activity of pests), and compounds used in defense affect the clock. New findings show how the clock regulates stomata opening/closure for defense, and how the defensive compound jasmonic acid influences the clock. This could lead to plants that are better at defending themselves, reducing the need for pesticides, and potentially influencing timing for human medical treatment. (2019-06-12)

A plastic pill for periodontal problems
Rutgers scientists today announced a revolutionary new treatment for killing the bacteria that attack gum tissue during periodontal disease, while also promoting healing and the regeneration of tissue and bone around the teeth. The breakthrough technology, employing a polymer-based drug delivery system that may be implanted in pockets between the teeth and the gum, was developed at Rutgers University. (2006-09-14)

Dual internal clocks keep plant defenses on schedule
Time management isn't just important for busy people -- it's critical for plants, too. A new study in the journal Nature shows how two biological clocks work together to help plants deal with intermittent demands such as fungal infections, while maintaining an already-packed daily schedule of activities like growth. The researchers also identified a gene that senses disturbances in the 'tick-tock' of one clock, and causes the other clock to tighten its timetable. (2015-06-22)

Agent that triggers immune response in plants is uncovered
Rsearchers at the Boyce Thompson Institute for Plant Research on the Cornell campus have identified how plants signal that they have been attacked in order to trigger a plantwide resistance. (2007-10-04)

Behind closed doors: Researchers show how probiotics boost plant immunity
Pathogens can slip through leaf pores and begin infecting a plant. University of Delaware researchers show that this invasion is halted when a probiotic is present in the soil where the plant is rooted. (2012-08-27)

Impregnating plastics with carbon dioxide
Everyone has heard that carbon dioxide is responsible for global warming. But the gas also has some positive characteristics. Researchers are now impregnating plastics with compressed CO2 in a process that could lead to new applications ranging from colored contact lenses to bacteria-resistant door handles. (2011-01-03)

Unearthing cornerstones in root microbiomes
A plant's immune system can distinguish between friends and foes among these microbes, and upon detecting pathogens, can produce regulatory chemicals called phytohormones to activate a defensive response. In a study published online July 16, 2015, in Science Express, a team including scientists from the US Department of Energy Joint Genome Institute looked at roles of three phytohormones in controlling the composition of the root microbiome in the model plant Arabidopsis thaliana. (2015-07-16)

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