Side Effects Current Events

Side Effects Current Events, Side Effects News Articles.
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Predicting potential pharma side effects
A computer program that can predict whether or not a given pharmaceutical will have worrying side effects has been developed by researchers in the USA. Md Jamiul Jahid and Jianhua Ruan of the Department of Computer Science, at the University of Texas at San Antonio, have developed the 'in silico' testing system for drugs in the early stage of drug development. (2016-03-08)

Concern over 'aggressive' cholesterol recommendations
New US recommendations for lowering cholesterol levels would increase the risk of harmful side effects with no overall reduction in deaths, warn experts in this week's BMJ. (2006-06-01)

Hospital follow-up services not necessary for all child cancer survivors
Many child cancer patients will benefit from ongoing follow-up, but others should be allowed to move on and put the experience of cancer behind them, say experts in this week's issue of the BMJ. (2008-04-03)

New report highlights aromatase inhibitor side effects
Breast Cancer Action released a report today, in conjunction with a poster presentation at the San Antonio Breast Cancer Symposium (Abstract #3131), on the side effects of aromatase inhibitors. Survey results show that nearly all respondents (96 percent) reported one or more side effects. Nearly 30 percent of the respondents reported discontinuing the use of an AI -- 84 percent because of intolerable side effects and close to half of them due to joint-related problems. (2006-12-15)

New method for uncovering side effects before a drug hits the market
Side effects are a major reason that drugs are taken off the market and a major reason why patients stop taking their medications, but scientists are now reporting the development of a new way to predict those adverse reactions ahead of time. The report on the method, which could save patients from severe side effects and save drug companies time and money, appears in ACS' Journal of Chemical Information and Modeling. (2013-01-02)

In worms, researchers uncover protein that may one day make opioid use safer
Studying mutant worms has led to the discovery of a receptor that reduces sensitivity to opioid side effects in these organisms. (2019-08-15)

Patients anticipate high number of side effects to cancer treatment
A new study finds patients about to undergo chemotherapy or radiation expect a high number of side effects, and that age, gender, educational background, and the type of cancer all influence how many side effects a patient expects. (2004-07-12)

Landscapes from the ancient and eroded lunar far side
This image, taken by the advanced Moon Imaging Experiment (AMIE) on board ESA's SMART-1 spacecraft, shows a highly-eroded highland area on the lunar far side, close to the equator. (2006-07-14)

Antidepressant side effects reported more by patients with co-occurring panic disorder
Patients who take medication for depression report more side effects if they also suffer from panic disorder, according to a new study led by researchers from the University of Illinois at Chicago published in the Journal of Clinical Psychiatry. (2017-01-03)

Stepping down inhaled steroids can cut side effects
A 'stepdown' approach to reduce doses of inhaled steroids in patients with chronic asthma can cut the risk of side effects without compromising asthma control, say researchers in this week's BMJ. (2003-05-22)

IMRT versus 3D CRT for prostate cancer, new long-term data assesses side effects
New research findings show men have fewer long-term gastrointestinal side effects with intensity-modulated radiation therapy (IMRT) than with three-dimensional conformal radiation therapy (3D CRT) for prostate cancer treatment, despite the higher doses of radiation used in the IMRT group. These and other data, including long-term genitourinary side effects, were presented today. (2006-11-05)

Are doctors missing depression medication side effects?
A study from Rhode Island Hospital shows that patients report side effects from medication for the treatment of depression 20 times more than psychiatrists have recorded in the charts. The researchers recommend the use of a self-administered patient questionnaire in clinical practice to improve the recognition of side effects for patients in treatment. The study is published in the Journal of Clinical Psychiatry. (2010-04-19)

Teaching old drugs new tricks
Researchers from the European Molecular Biology Laboratory discovered a new way to make use of drugs' unwanted side effects. They developed a computational method that compares how similar the side effects of different drugs are and predicts how likely the drugs act on the same target molecule. The study, published in Science this week, hints at new uses of marketed drugs. (2008-07-10)

CAMH discovery of novel drug target may lead to better treatment for schizophrenia
Scientists at the Centre for Addiction and Mental Health have identified a novel drug target that could lead to the development of better antipsychotic medications. Dr. Fang Liu, Senior Scientist in Centre for Addiction and Mental Health's Campbell Family Mental Health Research Institute and Professor in the Department of Psychiatry, University of Toronto, and her team published their results online in the journal Neuron. (2014-12-08)

Reducing side effects of painkillers
Cardiff University researchers have increased the understanding of why some painkillers increase the risk of heart attack and stroke. (2006-09-12)

Traditional Chinese medicinal herbs may help women with breast cancer
Using Chinese herbs either alone or in conjunction with chemotherapy may help protect a breast cancer patient's bone marrow and immune system, as well as improving the woman's overall quality of life. (2007-04-17)

A sleeping pill that doesn't make you sway: a new targeted insomnia treatment
University of Tsukuba researchers compared the physical and cognitive side effects of two sleep agents that affect two different kinds of brain receptor. Brotizolam, commonly prescribed for insomnia in Japan, affects GABA receptors, which are present throughout the brain. A newer agent, suvorexant, affects receptors that are specifically involved in wakefulness. Suvorexant was just as effective as brotizolam in terms of sleep duration and efficiency, and had fewer body balance side effects. Future large-scale trials are warranted. (2019-11-22)

Hormones increase side effects, complicate treatment decision for prostate cancer patients
A common treatment for some men with prostate cancer at risk of recurring may lead to prolonged survival, but a new study shows at what cost. (2003-10-21)

Scripps Florida scientists awarded $3 million to develop new, more effective pain treatments
Scripps Florida scientists have been awarded $3.1 million by the National Institute on Drug Abuse, part of the National Institutes of Health, to study and develop several new compounds that could prove to be effective in controlling pain without the unwanted side effects common with opiate drugs, such as morphine, Oxycontin®, and Vicoden®. (2012-02-29)

Patients may overestimate risk of side-effects from qualitative drug information
Authors of a research letter in this week's issue of THE LANCET are calling for EU guidelines to be reviewed after results of research which shows that patients only given qualitative information about the side-effects of drugs substantially overestimate their personal risk. (2002-03-07)

Estrogen treatment with no side-effects in sight
Estrogen treatment for osteoporosis has often been associated with serious side-effects. Researchers at the Sahlgrenska Academy, University of Gothenburg, Sweden, have now, in mice, found a way of utilizing the positive effects of estrogen in mice so that only the skeleton is acted on, current research at the Academy shows. (2011-04-11)

Homeopathic medicines: Can they help relieve side-effects of cancer therapy?
Drugs and radiotherapy given for cancer can cause unpleasant side effects such as nausea and vomiting, mouth sores, dermatitis and menopausal symptoms. Around a third of patients with cancer use complementary therapies, including homeopathic medicines, to try to reduce these side-effects. In a systematic review of randomized controlled trials, Cochrane researchers examined recent evidence for the safety and effectiveness of homeopathic medicines used in this way. (2009-04-14)

Variation in how side effects are reported clouds drug safety
University of Colorado Cancer Center study finds significant variation in how drug side effects are reported, potentially making some drugs seem safer or less safe than they really are. (2020-04-28)

Mouse brain rewires its neural circuits to recuperate from damaged neural function after stroke
Japanese research group led by Professor Junichi Nabekura in National Institute for Physiological Sciences, Japan, found that, after cerebral stroke in one side of the mouse brain, another side of the brain rewires its neural circuits to recuperate from damaged neural function. The Japan Science and Technology Agency supported this study. They report their finding in Journal of Neuroscience, on Aug. 12, 2009. (2009-08-21)

Conventional and new-generation antipsychotics may have similar neurological side-effects
Authors of a systematic review of antipsychotic drugs in this week's issue of The Lancet highlight how the better side-effect profile of new-generation drugs may not be as substantial as previously thought when compared with conventional antipsychotics. (2003-05-08)

Diabetes drug can prevent heart disease
The widely used diabetes medicine metformin can have protective effects on the heart, reveals a new study conducted at the Sahlgrenska Academy, at the University of Gothenburg, Sweden. (2012-03-25)

Breast cancer patients experience fewer side effects from anticancer drug
A new analysis has found that both real and sham acupuncture treatments may help alleviate side effects of drugs commonly used to treat breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help clinicians improve care for cancer patients. The results also raise the question of whether sham acupuncture is truly inert or may, like real acupuncture, have beneficial effects. (2013-12-23)

Breast cancer patients experience fewer side effects from anticancer drug when receiving acupuncture
A new analysis has found that both real and sham acupuncture treatments may help alleviate side effects of drugs commonly used to treat breast cancer. Published early online in CANCER, a peer-reviewed journal of the American Cancer Society, the findings may help clinicians improve care for cancer patients. The results also raise the question of whether sham acupuncture is truly inert or may, like real acupuncture, have beneficial effects. (2013-12-23)

Newly developed mathematical model could be used to predict cancer drug side effects
A research team at Kobe University Hospital have further illuminated the likelihood of cancer drug side effects that can occur due to genetic mutations in the drug-metabolizing enzyme. The team led by Dr. TAKAOKA Yutaka also developed a mathematical model by using the results of molecular simulation analyses to predict the possibility of side effects. It is hoped that this research will pave the way for effective predictions of cancer drug side effects and treatment results. (2019-12-20)

Transplant rejection drug holds promise for inflammatory eye disease
The immunosuppressive drug mycophenolate mofetil, used to prevent rejection of transplanted hearts, kidneys and livers, may also be effective in controlling inflammatory eye diseases, according to a study by researchers at Johns Hopkins' Wilmer Eye Institute. (2005-09-02)

Potential new tool to monitor radiotherapy side effects
Researchers in Manchester have investigated a patient-centered approach to assessing the side effects of radiotherapy and have shown that it may be able to improve the detection and management of treatment-related toxicity. (2015-01-07)

Scripps Florida scientists win $2.4 million to expand development of new pain therapies
Scientists from the Florida campus of the Scripps Research Institute have been awarded $2.4 million from the National Institute on Drug Abuse of the National Institutes of Health to expand development of new pain medications with fewer side effects than those currently available. (2015-05-06)

Men ignore serious health risks of steroid abuse in pursuit of the body beautiful
Many men continue to abuse steroids despite knowing that they have serious, life-limiting and potentially lethal side effects, according to findings to be presented in Lyon, at the European Society of Endocrinology annual meeting, ECE 2019. (2019-05-18)

UEA scientists separate medical benefits of cannabis from unwanted side effects
Scientists at the University of East Anglia have found a way to separate medical benefits of cannabis from its unwanted side effects. The research was carried out in mice, but it is hoped that the breakthrough will pave the way for safe cannabis-based therapies that do not cause alterations in mood, perception or memory. Last year the team discovered how the main psychoactive ingredient in cannabis, known as THC, reduces tumor growth in cancer patients. (2015-07-09)

UK Allied Health Professor Receives Patent On Using Lithium With AIDS Drugs
A University of Kentucky researcher has received a patent to test whether anti-viral drug agents can be more effective when made chemically as a lithium salt. He proposes that combining AIDS drugs with lithium salts could result in fewer toxic side effects and reduce the amount of virus in a person's system. (1999-01-06)

Drugs for hair loss and BPH may result in loss of libido, ED in men
Researchers from Boston University School of Medicine, in collaboration with colleagues at Lahey Clinic and from Denmark and Germany, have found that 5a-reductase inhibitors, while improving urinary symptoms in patients with benign prostatic hyperplasia and possible hair loss prevention, produces significant adverse effects in some individuals including loss of libido, erectile dysfunction, ejaculatory dysfunction and potential depression. These findings currently appear on-line in Journal of Sexual Medicine. (2011-01-11)

Cochrane review looks at the effectiveness and side effects of mefloquine
Researchers from LSTM Cochrane Infectious Diseases Group publish two systematic reviews this week about the safety of mefloquine (Lariam) for preventing malaria in travellers. (2017-10-30)

Identification Of Brain Areas Could Help Eliminate Side Effects Of Pain Medication
Researchers at Penn State's College of Medicine have identified a set of neurons in the brain that may contribute to some of the undesirable side effects of pain medication. (1998-05-08)

Adverse effects of common prostate enlargement and hair growth drugs: A review
Twenty-five percent of men currently taking Finasteride or Dutasteride, popularly known as Proscar and Avodart, for the treatment of benign prostate enlargement, appear not to benefit from taking these medications. Those prescribed Propecia or Avodart for male pattern hair loss (known as alopecia) are also at risk for adverse events elicited by these drugs. (2015-08-25)

Study reveals superior sedation method for children
Procedural sedation and analgesia is an essential element of care for children requiring painful procedures in the emergency department. Research led by Drs. Amit Shah, Gregory Mosdossy and Michael Rieder of the University of Western Ontario and Lawson Health Research Institute provides evidence that when compared to ketamine alone, patients who receive a combination of ketamine and propofol have a slightly faster recovery time and suffer from less severe side effects. (2010-10-19)

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