Tumors Current Events

Tumors Current Events, Tumors News Articles.
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Tumor-associated bacteria hitches a ride to metastatic sites
The same bacteria present in primary tumors of patients with colorectal cancer are also present in liver metastases, a new study finds. (2017-11-23)

Patients with non-functional adrenal tumors at increased risk of diabetes
Investigators from Brigham and Women's Hospital have found that 'non-functional' adrenal tumors can increase a person's risk of developing type 2 diabetes. (2016-08-01)

First drug target identified for children with rare type of brain tumor
Primitive neuroectodermal tumors are the largest group of malignant brain tumors in children. They can arise from the brain's cerebellum or from tissue located throughout the central nervous system. Little is known about how CNS-PNETs develop, although these tumors are more aggressive than other PNETs and have an overall survival rate of only about 20 percent. In a new study, researchers have identified a possible target for a new CNS-PNET therapy. (2016-07-13)

Drug/radiation combo may help shrink established tumors
Researchers may be closer to understanding why anti-cancer drugs such as Ipilimumab, which boost the tumor-killing power of immune cells, haven't fared well in clinical trials. The new study, which describes a way to enhance the ability of these drugs to shrink well-established tumors, will be published online on Aug. 25 in the Journal of Experimental Medicine. (2008-08-25)

MRI 'best' for looking at breast cancer and more
The use of MRI is effective in differentiating the blood supply to medial and lateral breast tumors, which is important in treatment planning and prognosis according to a study conducted by researchers at the University of Miami in Miami, Fla., and the Rabin Medical Center in Petah Tikva, Israel. (2008-04-11)

Drug-loaded beads may help treat liver cancer
A new phase 1 safety trial has demonstrated that idarubicin-loaded beads are well tolerated by patients but are toxic to liver cancer cells. Idarubicin is an anthracycline that is currently used to treat leukemias. (2014-10-06)

Attracting an immune response to cancer
Specialized immune cells known as natural killer (NKT) cells are recruited into human tumors and may help fight the cancer according to a report in the Journal of Experimental Medicine. The chemical attractant that draws in the NKT cells was also identified and may be used in the future to prevent the growth and spread of tumors. (2004-05-03)

Early trial hints CAR T cells may combat solid tumors in children with neuroblastoma
A phase 1 trial involving 12 children with relapsed neuroblastoma - a hard-to-treat pediatric cancer - shows that anticancer CAR T cells displayed signs of efficacy against these tumors while avoiding damage to nerve tissue. (2020-11-25)

Bright spot analysis for photodynamic diagnosis of brain tumors using confocal microscopy
A Japan-based research team led by Kanazawa University have found that bright spot areas have generally lower fluorescence in brain tumors than in normal tissues in images captured by irradiation with a 405 nm wavelength laser and 544.5-619.5 nm band-pass filter. This may facilitate discrimination of glioblastoma with or without 5-aminolevulinic acid fluorescence and could be applicable to other tumors. (2019-04-11)

Reversing t cells' misunderstood rep in responding to a pediatric leukemia
A study of pediatric patients with leukemia demonstrates that they were able to generate T cells against tumor-associated mutations, contradicting previous assumptions that T cells cannot be effectively unleashed on pediatric tumors. (2019-06-26)

Radiofrequency ablation highly effective in treating kidney tumors
A relatively new, minimally invasive treatment was 93 percent successful in eradicating malignant kidney tumors, according to a recent study conducted by researchers from Wake Forest University Baptist Medical Center in Winston-Salem, N.C. (2007-08-03)

Jumbled chromosomes may dampen the immune response to tumors
How well a tumor responds to immunotherapy may depend in part on whether its chromosomes are intact or in a state of disarray, a new study reports. The finding could help doctors better pinpoint which cancer patients would benefit from immunotherapy. (2017-01-19)

Research reveals how succinate dehydrogenase is linked to both tumor and neurodegeneration
Sarah Fendt (VIB-KU Leuven): 'In this project we studied mutations in enzyme succinate dehydrogenase, which are associated with tumors, but also neurodegeneration. This is interesting, because tumors are defined by cells that show sustained proliferation and in this sense sustained fitness, while neurodegeration is defined by cells of impaired fitness. It is surprising that mutations in one and the same enzyme, which all lead to loss of enzyme expression result in two distinct disease phenotypes.' (2016-11-15)

JNCI news brief: Breast cancer hormone receptor status and risk of a second primary tumor
Women with hormone receptor negative first tumors have twice as much risk for developing a second breast cancer as women with HR-positive tumors, according to a study published online July 9 in the Journal of the National Cancer Institute. (2009-07-09)

Mutational intensity influences a tumor's response to PD-1 immunotherapy
Following FDA approval last year of PD-1 immune checkpoint inhibitors for tumors with mismatch repair deficiency, a new study reveals more about why responses of these tumors to this immunotherapy vary, specifically implicating mutation intensity. (2019-05-02)

Gene may lead to early onset of brain tumor
People with a particular gene variant may be more likely to develop brain tumors, and at an earlier age, than people without the gene, according to a study published in the Jan. 27, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. (2009-01-26)

Washington University review identifies factors associated with childhood brain tumors
Older parents, birth defects, maternal nutrition and childhood exposure to CT scans and pesticides are increasingly being associated with brain tumors in children, according to new research from the Brown School at Washington University in St. Louis. (2014-10-02)

Marker Found For The Most Malignant Brain Tumors
Researchers at Penn State's College of Medicine have identified what could be a marker for certain types of brain tumors. This marker would be a valuable diagnostic tool for physicians who deal with patients with these tumors. (1999-05-10)

RFA safe for treating liver tumors pushing on GI tract; Alcohol injection makes RFA more effective
Radiofrequency ablation (RFA), the use of electrodes to heat and destroy abnormal tissue, is a safe and effective treatment for eradicating liver tumors that are in contact with the gastrointestinal (GI) tract, says one study in the November 2004 issue of the American Journal of Roentgenology, while a separate study in that same issue says that RFA becomes even more effective when alcohol is injected into a liver tumor before an RFA procedure. (2004-11-02)

A mechanistic approach to neuroblastoma prognosis and risk
A new study reveals key molecular indicators that could help doctors select the best form of treatment for patients with neuroblastoma -- the most common type of cancer in infants. (2018-12-06)

MRI technique for measuring blood volume helps distinguish between abscesses and tumors in the brain
Dynamic susceptibility contrast (DSC) MRI allows physicians to differentiate between cerebral abscesses--inflamed areas in the brain caused by infection--and malignant brain tumors without surgery, says a new preliminary study by researchers from Duke University Medical Center in Durham, NC. (2004-11-08)

Young women's breast cancers have more aggressive genes, worse prognosis
Young women's breast cancers tend to be more aggressive and less responsive to treatment than the cancers that arise in older women, and researchers at the Duke Comprehensive Cancer Center and the Duke Institute for Genome Sciences & Policy may have discovered part of the reason why: young women's breast cancers share unique genomic traits that the cancers in older women do not exhibit. (2008-07-08)

Jefferson researchers identify possible imaging method to stratify breast cancer without biopsy
Scientists from the Kimmel Cancer Center at Jefferson have discovered a possible way for malignant breast tumors to be identified, without the need for a biopsy. The findings were published online ahead of print in the Journal of Nuclear Medicine. (2009-12-17)

Retraining immune cells to kill tumors
Tumors escape destruction by immune cells by turning off their tumor killing functions. A team of scientists in the UK have now found a way to retrain the impotent cells into potent tumor destroyers. Their study will be published online May 19 in the Journal of Experimental Medicine. (2008-05-19)

Tiny radioactive spheres effectively treat cancer that has spread to the liver
Placing tiny radioactive spheres directly into the liver through its blood supply halted growth of tumors that had spread to the organ in 71 percent of patients tested in a small clinical trial, researchers from Mayo Clinic Jacksonville report. (2007-10-29)

New therapy on horizon for the treatment of pituitary tumors
Pituitary tumors are associated with significant morbidity. In many cases however, no suitable drug therapies are available and surgical excision is currently the only effective treatment. Researchers have now found a receptor present in these tumors that upon activation with specific drug compounds is capable if inhibiting pituitary tumor growth. (2003-05-01)

Exposure to atomic bomb radiation associated with nervous system tumors
A study of the effects of radiation exposure among Japanese atomic bomb survivors has found that exposure to even moderate doses of radiation is associated with an increased incidence of nervous system tumors. The finding appears in the October 16 issue of the Journal of the National Cancer Institute. (2002-10-15)

Hammering cancer cell survivin
In a recent issue, Mesri et al. reported that the apoptosis inhibiting protein survivin can be inhibited in a wide variety of tumor cells using a dominant negative form of the protein. Survivin is expressed normally in early development and is found in tumors of many sorts, but few healthy adult cell types express it. (2002-01-16)

Resistance mechanism of aggressive brain tumors revealed
Brain tumors subject to therapy can become resistant to it through interactions with their tumor microenvironment rather than because of anything intrinsic about the tumor itself, a new study in mice suggests. (2016-05-19)

A comprehensive survey reveals bacteria are widespread in human tumors and differ by tumor type
Different human tumor types each harbor their own unique bacterial communities, researchers report in a new study that profiled the microbiomes of more than 1,500 individual tumors across seven types of human cancer - the most comprehensive tumor microbiome study to date. (2020-05-28)

Pesticide use during pregnancy linked to increased risk of childhood brain tumors
Previous epidemiological studies have suggested that exposure to pesticides during pregnancy may have a possible role in the development of childhood brain tumors. (2017-10-03)

Researchers take a major step in reclassifying brain tumors with precision
A Cancer Genome Atlas study on diffuse gliomas finds genomic analysis predicts tumor behavior better than microscope appearance (2015-06-10)

Breaking the backbone of triple-negative breast cancers
Putting the brakes on an abundant growth-promoting protein causes breast tumors to regress, according to a study in the Journal of Experimental Medicine. (2012-03-19)

Tumor size related to lung cancer spread
Smaller tumors in the lungs appear to be less likely to have spread than larger tumors among patients with asymptomatic lung cancer, suggesting that early screening may be useful in detecting cancers that are still curable, according to a new article in the February 13 issue of Archives of Internal Medicine, one of the JAMA/Archives journals. (2006-02-13)

Family history of brain tumors linked to increased risk of brain cancer
People with a family history of cancerous brain tumors appear to be at higher risk of developing the same kind of tumors compared to people with no such family history, according to a study published in the Sept. 23, 2008, issue of Neurology, the medical journal of the American Academy of Neurology. (2008-09-22)

Rat study shows gut microbes play a role in colon cancer susceptibility
The microscopic organisms that live in our gut do more than help us digest food. A new study in rats bolsters a growing body of evidence that the complex mix of microorganisms found in the gut, known as gut microbiota, could influence a person's likelihood of developing colon cancer. (2016-07-13)

New Cancer Procedure At Wake Forest University Baptist Medical Center Offers Hope
Wake Forest University Baptist Medical Center is the only facility in the Southeast offering a new procedure for malignant tumors previously thought untreatable. The procedure is called Tumor Ablation using Radiofrequency Energy. (1999-04-09)

Radiofrequency ablation safe and feasible for eradicating lung tumors
Radiofrequency ablation (RFA), the use of electrodes to heat and destroy abnormal tissue, is a promising technique to safely and effectively treat patients with inoperable lung tumors, say researchers from the IRCCS Hospital of Oncology in Bari, Italy. (2004-08-01)

In cancer-ridden rats, loneliness can kill
Socially isolated female rats develop more tumors -- and tumors of a more deadly type -- than rats living in a social group, according to researchers at Yale University and the University of Chicago. (2009-12-07)

Adding tools against breast tumors
At the end of a 10-year, coast-to-coast study of women with an unusual form of breast cancer, Richard J. Barth Jr., M.D., and three fellow researchers are making the case for a particular combination of treatments to stop the tumors in their tracks. (2009-10-27)

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