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Preserving nerve cells in motor neuron disease
A team of researchers, reporting in the Journal of Clinical Investigation, has identified a way to prevent symptom onset, weight loss and paralysis, and extend survival in a mouse model of amyotrophic lateral sclerosis (ALS, also known as Lou Gehrig's disease), providing a new avenue of research for the development of therapeutics for ALS and other motor neuron diseases. (2010-09-20)

Is it alive or dead?
A group of mechanical engineers from Pohang University of Science and Technology in Korea describe a way to measure the thermal conductivity of single cells in the journal Applied Physics Letters, and they measured significant difference between dead and living cells, suggesting a new way to probe for biological activity. (2013-06-28)

Dead or alive? A new test to determine viability of soybean rust spores
Spores from Asian soybean rust pose a serious threat to soybean production in the United States because they can be blown great distances by the wind. University of Illinois researchers have developed a method to determine whether these spores are viable. (2012-12-11)

Cannabinoid compounds may inhibit growth of colon cancer cells
Medical marijuana has gained attention in recent years for its potential to relieve pain and short-term anxiety and depression. Now, Penn State College of Medicine researchers say some cannabinoid compounds may actually inhibit the growth of colon cancer cells in the lab. (2019-02-05)

Traffic noise makes mating crickets less picky
New research has found that the mating behaviour of crickets is significantly affected by traffic noise and other man-made sounds. When man-made noise pollution was present, the females didn't take into account the courtship song of the male crickets during mating. As the courtship song is energetically costly and provides crucial information about the health of the male, this could affect long-term population viability as females could choose less suitable mates. (2021-02-01)

Grant for research that could lead to new therapies for Parkinson's Disease
A team of scientists led by researchers at Plymouth University Peninsula Schools of Medicine and Dentistry, has received a grant from the Medical Research Council for work which could lead to new and effective therapies for those with Parkinson's Disease. (2014-04-22)

Jekyll and Hyde cells: Their role in brain injury and disease revealed
New research has shown how normally helpful brain cells can turn rogue and kill off other brain cells following injury or disease. (2017-02-02)

The song doesn't remain the same in fragmented bird populations
Paola Laiolo and colleagues at the Spanish Council of Research studied the metapopulation system of the Dupont's lark in northeastern Spain, and found an association between individual song diversity and the viability of the population as a whole, as measured by the annual rate of population change. This association arises because males from the most numerous and productive populations, i.e. those less prone to extinction, sang songs with greater complexity. The findings are published in this week's PLoS ONE. (2008-03-18)

Further evidence shows clinical viability of natural tooth repair method
Over the last five years scientists at King's College London have been investigating a method of stimulating natural tooth repair by activating cells in the tooth to make new dentine. In a paper published today in the Journal of Dental Research, they have found further positive evidence that the method has the potential to be translated into a direct clinical approach. (2020-03-10)

BPA in dialysis machine components may be toxic to patients' cells
Viability, necrosis, and death of immune cells are influenced by BPA concentrations in components of dialysis machines. Alternative polymers for dialysis machine components may reduce cells' exposure to BPA during dialysis. (2013-11-07)

What does trophy hunting contribute to wild lion conservation?
Trophy hunting of lions, the killing of selected individual animals for sport, is highly controversial, and there is much debate about what it contributes to conservation. (2017-07-31)

Pregnancy loss and the evolution of sex are linked by cellular line dance
In new research published this week (Aug. 1, 2017) in the Proceedings of the Royal Society B, Levitis and his collaborators report that meiosis takes a heavy toll on the viability of offspring. And not just for humans. Creatures from geckos to garlic and cactuses to cockroaches pay a price to undergo sexual reproduction. (2017-08-01)

Study investigates the quality of organs from potential donors with HIV
In 2013, the United States government passed the HIV Organ Policy Equity (HOPE) Act, which allows research to be conducted on the safety of organ donation from deceased donors with HIV to recipients with HIV. (2015-05-14)

A metabolic means to preserving egg supply and fertility
The stresses that come with aging, chemotherapy treatments, and environmental exposures all threaten fertility. But what if there were a way to preserve women's limited egg supply? Researchers reporting on studies conducted in frog and mouse eggs in the Cell Press journal Molecular Cell on Oct. 3rd may have found a way. The findings come at an important time when many women are waiting longer and longer to have children. (2013-10-03)

The secret life of seeds to be discussed at symposium
Vigor, viability and dormancy are keys to the success of seeds (2015-10-20)

Study examines interventions for extremely preterm infants
When compared with infants born between 1993 and 1995, more infants born at 22 to 24 weeks' gestation at one academic medical center in 2001 to 2003 received life-sustaining interventions but were no more likely to survive, according to a report in the October issue of Archives of Pediatrics & Adolescent Medicine, one of the JAMA/Archives journals. (2009-10-05)

Not all stem cells are equally efficient for use in regenerative medicine
Scientists at the University of Granada and Alcala de Henares University have concluded that, contrary to what was thought, only a specific group of cord blood stem cells maintained in culture are useful for therapeutic purposes. (2013-01-09)

Fishing can disrupt mating systems
In many fish species body size plays an important role in sexual selection. Large individuals are preferred mating partners because they can enhance offspring survival by providing better quality resources than small individuals. While large females and males are often favored by sexual selection, fishing targets and removes these reproductively superior individuals. Academy Research Fellow Silva Uusi-Heikkilä discusses in her recent literature review the implications fisheries selection might have on sexual selection, individual reproductive success and population viability. (2020-05-08)

Liver cells benefit from mesenchymal stem cell co-culture prior to transplantation
Hepatocyte transplantation is an accepted therapy for acute liver failure for liver regeneration or as a bridge to liver transplantation. However, maintaining the viability and functional aspects of hepatocytes has been a concern even with successful cryopreservation. To improve the viability and function of cryopreserved hepatocytes prior to transplantation, researchers co-cultured hepatocytes with human mesenchymal stem cells derived from umbilical cord or fat tissues and found that the co-culturing confers improved hepatocyte survival and function. (2013-12-18)

Ingredient that makes curry yellow effective against melanoma cells
Curcumin, the yellow pigment found in the spice turmeric and a key ingredient in yellow curry inhibits melanoma cell growth and stimulates tumor cell death, according to a new study. (2005-07-11)

Prenatal BPA exposure may contribute to the male bias of autism spectrum disorder
Autism has a higher prevalence in males than females. Bisphenol A (BPA) is a common chemical found in plastics, our food, and even the human placenta. Higher prenatal exposure to BPA is thought to increase the risk of autism. Researchers have, for the first time, identified autism candidate genes that may be responsible for the sex-specific effects of BPA. (2021-01-19)

There's no magic number for saving endangered species
A new study offers hope for species such as the Siberian tiger that might be considered (2011-05-16)

Automatic slicing system: Ex-vivo culture normal and cancerous pancreatic tissue
Novel treatments are needed to improve the poor prognosis of patients suffering from pancreatic cancer. Lack of pre-clinical models that reliably predict the efficacy of a potential treatment in patients impair development of these novel therapies. A group from Amsterdam developed a system to culture ex-vivo pancreatic cancer specimens obtained from resection material and showed that it can be used to test the efficacy of a novel treatment option such as gene therapy. (2009-03-24)

$1.2M USDA grant to study Northeast organic farming
The U.S. Department of Agriculture's Initiative for Future Agriculture and Food Systems has awarded a $1.2 million grant for the creation of a new organic farming network managed by Cornell University's Department of Horticulture. (2001-12-07)

Hardy bacteria help make case for life in the extreme
The bottom of a glacier is not the most hospitable place on Earth, but at least two types of bacteria happily live there, according to researchers. (2012-01-19)

The effect of the GDNF on the activity of neural networks during hypoxic damage has been studied
Searching for ways to reduce losses from ischemic stroke, a major problem worldwide, is an extremely important task for many areas of public health and economy. So far, no effective and safe methods have been developed for treating ischemic brain damage. One of the most promising approaches to the development of treatment methods is to use endogenous molecules. (2018-02-19)

How viable is your liver after you die?
In a paper to be published in a forthcoming issue of TECHNOLOGY, a group of researchers from Harvard Medical School have done a study on the viability of donated livers and its correlation with donor demographics. The results of this study could reduce the number of livers that are discarded and facilitate development of novel therapeutics and bioengineering for clinical research applications. (2019-05-13)

'Squishiness' can indicate embryo viability, Stanford researchers find
A team of bioengineers and physicians has found that the squishiness of an hour-old fertilized egg can predict its viability, a metric that could lead to safer, more successful IVF pregnancies. (2016-02-24)

Titanium oxide nanotubes facilitate low-cost laser-assisted photoporation
Toyohashi University of Technology developed a nanosecond pulse laser-assisted photoporation method using titanium-oxide nanotubes (TNTs) for highly efficient and low-cost intracellular delivery. HeLa - human cervical cancer cells were cultured in the nanotubes and submerged in a solution of biomolecules. After cells were exposed to nanosecond pulse laser, we successfully delivered propidium iodide (PI) and fluorescent dextran into cells with high efficiency and cell viability. (2021-01-25)

New technique for sorting live cells may expedite biomedical research
Researchers from North Carolina State University and University of North Carolina at Chapel Hill have developed a new technique that uses sound waves to rapidly separate selected collections of cells for use in biomedical research. (2012-10-17)

A new role for milk: Delivering polyphenols with anti-cancer activity
Polyphenols found in tea manifest anti-cancer effects but their use is limited by poor bioavailability and disagreeable taste. A new study in the Journal of Dairy Science® finds that when epigallocatechin gallate (EGCG), the major extractable polyphenol in green tea and the most biologically active, when diluted in skim milk or other milk complexes remains bioactive and continues to reduce colon cancer cell proliferation in culture at concentrations higher than 0.03 mg of EGCG/mL. (2013-12-19)

SwRI scientists dig into the origin of organics on Ceres
Since NASA's Dawn spacecraft detected localized organic-rich material on Ceres, Southwest Research Institute (SwRI) has been digging into the data to explore different scenarios for its origin. After considering the viability of comet or asteroid delivery, the preponderance of evidence suggests the organics are most likely native to Ceres. (2017-10-18)

What is the pathogenesis of liver damage induced by ethanol?
They investigated the effects of ethanol on the IGF-I system with the involvement of JNK1/2 activity and ADH by using each chemical inhibitor in primary cultured rat hepatocytes. The results indicate that ethanol inducedp-JNK1/2 activation is associated with the IGF-I system and cell viability in hepatocytes. Furthermore, alcohol dehydrogenase is involved in the relationship between ethanol-induced inactivation of p-JNK1/2 and the changes of the IGF-I system and cell viability. (2008-10-07)

Neonatal livers better source for hepatocytes than adult livers
The source of liver cells for transplantation is primarily from adult livers found unsuitable for organ transplantation. Neonatal livers are an alternative source because they are too small for organ transplantation, yet have good quality cells. A high-yield preparation of viable liver cells, isolated for transplantation from frozen, banked 1- to 23-day-old neonatal livers, were assessed for quality and function and found to have better thawing recovery than hepatocytes from adult livers. (2013-09-17)

Can ecotourism save endangered species?
Using population viability modelling, Griffith University researchers Professor Ralf Buckley, Dr. Guy Castley and Dr. Clare Morrison have developed a method that for the first time quantifies the impact of ecotourism on threatened species. (2016-02-17)

Cryopreservation of induced pluripotent stem cells improved the most by one product
To determine the best cryopreservation solution to maintain induced pluripotent stem (iPS) cells, researchers compared 12 commercially prepared and readily available cryopreservation solutions and found that (2012-09-25)

Vapor from glo™ had little or no biological impact on cells in laboratory tests
Unlike smoke, vapor from tobacco heating product -- gloTM -- is not toxic, does not cause oxidative stress, gene mutations or the promotion of tumors in cells in laboratory tests. gloTM, a tobacco heating device, heats rather than burns tobacco. It is well established that it is the toxicants produced by burning tobacco that are responsible for causing most smoking-related diseases. The numbers and levels of toxicants in gloTM emissions are significantly lower than in cigarette smoke, meaning it has the potential to be reduced risk. (2017-10-24)

A new method allows to detect the presence in ham of the parasite that causes toxoplasmosis
Scientists from the universities of Granada and Valencia have developed a new molecular method for determining the presence of the parasite Toxoplasma gondii, which causes toxoplasmosis, in samples of ham. (2016-11-04)

New approach to fighting cancer could reduce costs and side effects
CAR-T biotherapeutics company Carina Biotech and researchers at the University of South Australia have developed a novel approach based on microfluidic technology to ''purify'' the immune cells of patients in the fight against cancer. (2020-10-20)

Cell suicide prevention squad
OIST researchers discover mechanisms aiding cell viability and survival. (2015-12-04)

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