Articles tagged with Gut Microbiota
Researchers found that eliminating sugar from a low-fat diet can lead to impaired glucose control, insulin resistance, and gut microbial imbalance. Balanced dietary carbohydrates are essential for supporting gut and immune homeostasis.
NUTRITION 2026 brings together thousands of researchers and health professionals to share new evidence on protein needs, infant formula regulation, microbiome mysteries, and more. The meeting features over 1,650 scientific studies and provides a platform for experts to discuss the future of nutrition science.
New research links food insecurity to altered gut microbiomes in children, with potential implications for child health and development. The study found higher levels of certain bacteria, such as Sutterella, in children from food-insecure households.
Researchers investigated the interplay between host and gut microbiota in selenium metabolism, finding that gut microbiota transform selenium into metabolites influencing utilization, detoxification, and excretion. The study also revealed that Se intake affects bacterial diversity and that gut microbes produce unique selenometabolites.
A new mathematical model developed by Arizona State University researchers estimates how much of the calories people absorb from food, considering the role of gut microbes. The model, DAMM, suggests that short-chain fatty acids produced by gut microbes contribute to an average of about 140 calories per day.
A study by Harvard T.H. Chan School of Public Health found that gut microbiome alterations persist even after adenoma removal, increasing the risk of colorectal cancer. The researchers discovered that diet and physical activity were closely tied to CRC-associated gut microbes, suggesting lifestyle habits may contribute to sustained risk.
A new screening tool tests for microbial metabolites in urine to identify children at risk for autism, with 90% sensitivity and 100% specificity. The test may guide more targeted interventions, including approaches to restore a healthy gut microbiome.
Researchers found that the gut responds to protein deficiency by activating a fast neural circuit and a slower hormonal signal, which selectively changes dietary priorities. The study reveals a previously unknown gut-brain signaling system that rapidly alters feeding behavior in animals.
A study reveals that medical exposure can rapidly change the human microbiome, with gut microbes shifting toward patterns more commonly seen in urban populations. The research found a decline in microbial diversity and a shift towards bacterial groups more common in industrialized societies.
Researchers found that gut luminal exosomes from older animals carried molecular signals associated with insulin resistance, inflammation and disruption of the gut barrier. Transferring these to young animals elicited similar effects, while transferring exosomes from young animals to older animals mitigated metabolic aging findings.
Researchers discovered that Akkermansia bacteria, which aid human digestion, also thrive in the ocean by breaking down seaweed sugar. This finding highlights the importance of these bacteria in both human health and marine ecosystems.
Researchers tracked six NCAA Division I football players over a season and found that non-concussive head impacts correlated with changes to the gut microbiome. The study suggests that even sub-symptomatic head impacts might affect the gut microbiome, both in the immediate aftermath of injury and over a longer time course.
A review from Florida Atlantic University links obesity to Alzheimer's disease through disruptions in metabolism, highlighting the importance of mitochondrial function and gut-brain axis balance. Early detection and whole-body prevention may become possible through monitoring metabolic health.
Researchers at Vanderbilt University Medical Center discovered that enterotoxigenic Bacteroides fragilis reshapes intestinal cell metabolism to support its growth, causing diseases like diarrhea and colorectal cancer. The study provides new possibilities for intervention by targeting metabolic interactions between host and microbes.
Researchers found that microbes actively adjust their behavior to minimize competition and conflict when living together, leading to more efficient coexistence. This discovery provides insights into how diverse microbial communities assemble and persist despite intense competition.
A new review found that lifestyle behaviors like physical activity and diet can positively modulate the gut microbiome of cancer patients, but these effects are often influenced by non-modifiable variables. The study also highlighted the role of intrinsic patient characteristics in shaping microbial composition.
Researchers from NUS engineered bacteria to restore metabolic balance across the gut, liver and brain, reducing brain toxins and preventing neurological symptoms. The approach preserves the natural diversity of the gut microbiome and has shown promising results in long-term safety studies.
Researchers found that antibiotics disrupt gut microbiota, suppressing protective immune system pathways and increasing severity of A. baumannii pneumonia. The study highlights the gut-lung connection as a potential therapeutic target for hospital-acquired lung infections.
Researchers found that restoring a young microbiome can reverse features of aging in the liver, including inflammation and DNA damage. The study suggests that a healthy gut microbiome plays a key role in preventing liver cancer.
Researchers are close to building a 'virtual gut' capable of predicting responses to diet, drugs, and microbiome-based therapies. A new review outlines an analytical framework for host-microbiome multi-omics studies, covering preprocessing, feature selection, data integration, predictive modeling, and evaluation.
Researchers have developed a universal toolkit for editing bacterial DNA in 15 diverse species, including human pathogens and fast-growing biotechnology organisms. The technology uses retrons, an immune system that produces DNA, to efficiently modify genes, with varying success rates across different species.
Researchers found distinct gut microbiome characteristics that predicted treatment response to the low FODMAP diet and rifaximin. Patients who responded to these treatments had different microbial signatures, with increases in diversity for those on the low FODMAP diet and resilience against antibiotics for those on rifaximin.
A new study found that breast milk helps maintain a balance of beneficial bacteria in babies' developing gut microbiomes, including E. coli and Bifidobacterium. This mutualistic relationship supports healthy infant development and may have implications for future synbiotics.
A recent study found that antibiotic-resistant bacteria are present in the gut microbiomes of American black bears in eastern North Carolina. The researchers also discovered that these pathogens can be dispersed through bear feces, making the bears a potential indicator species for environmental changes.
A new study reveals that people with Parkinson's disease have a distinct gut microbiome, as do those at genetic risk but without symptoms. This could lead to early detection and potential prevention strategies.
Researchers identify specific chemicals that trigger neural activity in nematodes when they detect certain bacteria, leading to changes in feeding behavior and avoiding harmful pathogens. The study sheds light on fundamental mechanisms of how neurons interact with bacteria, paving the way for potential therapeutic interventions.
A study analyzing meconium samples from newborns found high prevalence of antibiotic resistance genes, including those linked to carbapenem resistance. The findings suggest that maternal transmissions and early hospital exposure contribute to the establishment of these genes in the neonatal gut.
A study of 153 Chilean older adults with cognitive concerns found a link between the gut microbiome's neuroactive potential and mental health status. The research suggests that alterations in the gut microbiome may contribute to depression and cognitive decline in this population.
Researchers found that gut microbial communities in estuarine fish are driven by functional traits rather than evolutionary history. The study identified three distinct enterotypes associated with dietary habits and migratory behaviors, revealing specific metabolic adaptations tailored to each host's lifestyle.
Researchers at DTU have developed a new method to identify bacteria capable of producing vitamin B2 in soya drinks. A bacterium from bumblebee guts was found to thrive in plant-based dairy alternatives and produce the nutrient in high quantities.
A new study from the University of East Anglia found that living with friends may alter your gut bacteria, with social closeness driving the exchange of anaerobic microbes. The research suggests that daily interactions at home, such as hugging and sharing food prep spaces, may encourage the transfer of beneficial gut bacteria.
A large study led by Cedars-Sinai Health Sciences University found that long-term use of antidepressants and some antidiarrheal medications may be associated with a higher risk of death. The study analyzed nearly two decades of electronic health records from over 650,000 US adults with IBS.
A new study from the University of Minnesota Medical School demonstrated that fecal microbiota transplantation (FMT) can rapidly reverse systemic inflammation and improve survival in patients with fulminant C. difficile infection. The treatment protocol achieved a 78% 30-day survival rate among 18 critically ill patients.
The tumor microbiota is now considered a crucial component of the tumor microenvironment, influencing cancer development and modulating immunotherapy effectiveness. Researchers have identified ways microbes can remodel tumors' microenvironments, directly interacting with tumor tissue and immune cells.
Researchers discovered subtle changes in the blood can reveal early signs of cognitive decline caused by chemicals produced by gut bacteria. A blood test may one day transform how we detect dementia, potentially identifying people at risk years before symptoms appear.
Research systematically maps how bacterial metabolites influence disease progression and immune cell functions, highlighting their dual effects on the body. The review emphasizes the need for holistic regulation of metabolite profiles to achieve precision interventions.
Researchers developed two neural network models predicting human biological age based on blood biochemistry and gut microbiota. The models demonstrated high predictive accuracy and explainability, holding potential for monitoring intervention effects in clinical trials.
Researchers found that an imbalanced gut microbiome escalates the production of metabolic byproducts, driving a feedback loop that worsens CKD. Blocking a single enzyme in the gut stopped this cycle, suggesting iNOS as a potential target for treatment.
A study by Florida Atlantic University researchers has uncovered the impact of stress on wild songbirds, finding that even mild challenges can alter the gut microbiome, leading to changes in health indicators such as beak color and stress hormone levels.
A high-fat diet allows bacteria to move from the gut to the brain in mice, according to a new study. Researchers found that a small number of bacteria translocated to the brain, likely via the vagus nerve, and that these bacteria were also detected in mouse models of Alzheimer's, Parkinson's, and autism.
Researchers studied the Seychelles warbler's gut bacteria, finding that immune genes influence which microbes thrive, and that this relationship affects host health and survival. The study suggests a two-way relationship between immune genes and gut bacteria, with potential benefits for human health and disease prevention.
Researchers discovered that the aging gastrointestinal tract produces specific molecules that blunt the activity of a key gut-brain neuronal pathway, leading to age-related cognitive decline. Stimulating specific gut sensory neurons and targeting the vagus nerve can restore youthful cognitive function in old mice, suggesting that brain...
Emerging research reveals the gut microbiota plays a decisive role in shaping treatment outcomes for cancer immunotherapy. Beneficial bacteria enhance anti-tumor immunity by producing immune-active metabolites and activating key immune cells.
Researchers genetically modified a probiotic yeast to reduce its virulence in immunocompromised patients. The modified yeast was found to be less likely to cause infection, with improved survival rates in animal models.
Recent studies identify distinct gut microbial communities in people with dyslipidemia, suggesting a connection between the gut microbiome and heart disease precursor. The researchers found higher levels of Bacteroides caccae and lower levels of bacteria linked to metabolic stability. Future research aims to restore functional balance ...
Researchers found that specific gut bacteria can sense diet and translate information into signals that tell fat cells to burn energy. A low-protein diet activated precise gut microbes that promote beige fat production, leading to improved glucose control and lower cholesterol levels.
A new study reveals that fecal transplants from older female mice significantly improve ovarian function and fertility in young mice. The transplants show a direct link between the gut microbiome and ovarian health, with potential implications for fertility and overall health as women age.
Researchers discover that butyric acid, a gut microbiota-derived metabolite, enhances the activity of natural killer cells expressing CX3CR1, restoring immune cell migration and cytokine production. This gut-lung immune axis may be harnessed to improve outcomes in severe bacterial infections.
Recent studies show that T cells support milk production and have lasting effects on maternal health and infant immunity. The review highlights emerging evidence of the crucial role of immune cells in lactation, which can inform strategies to improve maternal and infant health outcomes.
Researchers at Houston Methodist found that short-term antibiotic treatment significantly reduced neuroinflammation and neurodegeneration following traumatic brain injury by altering the gut microbiome. Beneficial bacteria Parasutterella excrementihominis and Lactobacillus johnsonii drove cell repair, while reducing harmful gut bacteria.
Researchers at Rutgers University created a new metric called the Ecological Network Balance Index to track how gut bacterial communities shift between health and disease. The index consistently separated healthy individuals from patients with multiple diseases, including colorectal cancer.
A study in Science reveals that a healthy gut microbiota enhances immunotherapy's efficacy against cancer, while antibiotics reduce diversity and may impair treatment. Analysis found specific bacterial species associated with better clinical outcomes.
Research found that people living in deprived areas have less diverse gut microbiomes, leading to increased inflammation and poorer metabolic health. The study identified 12 bacterial species associated with deprivation, including those negatively linked to anxiety and diabetes.
A global team of scientists, led by University of Houston microbiologist Madhan Tirumalai, has identified the critical role of biofilms in human space exploration. Biofilms could influence astronaut health, drug delivery and space agriculture, while also posing risks to astronaut health.
A new study reveals that a high-fat, high-sugar diet during early life can lead to long-lasting changes in feeding behavior and disrupt brain pathways involved in appetite control. However, targeting the gut microbiota with specific strains of beneficial bacteria or prebiotic fibers may help mitigate these effects.
Researchers identified genes that are activated when yeast cells are in the gut, suggesting a roadmap for engineering more efficient drug-delivery vehicles. The study found that yeast cells were digesting more lipids than carbohydrates in the gut, highlighting potential modifications to improve efficiency.
Two gut bacteria, Akkermansia muciniphila and Bacteroides thetaiotaomicron, work together to destroy intestinal mucus, leading to dry and immobile stool. This discovery explains why standard treatments often fail for millions with chronic constipation, including those with Parkinson's disease.
A new study uses metabolic modeling to predict which probiotics will successfully establish themselves in a person's gut and how prebiotics affect short-chain fatty acid production. The findings demonstrate the utility of these models for personalized probiotic and prebiotic interventions.