Articles tagged with Chemical Compounds
The Acceleration Consortium and Structural Genomics Consortium collaborate to develop new drugs using AI-driven lab capabilities. The partnership aims to speed up the discovery of bioactive molecules, advancing human health and disease understanding.
The National Institute of Standards and Technology (NIST) has released an updated library of mass spectra, known as 'chemical fingerprints', for identifying unknown substances. The expanded library contains over 382,000 compounds, including 35,000 new additions.
A University of Cincinnati research team will examine how microplastics and nanoplastics accumulate in the body and affect cardiovascular health, with a focus on potential toxicity and worsening outcomes after a heart attack. The five-year study aims to advance understanding of microplastic impact on heart diseases.
Researchers at the University of Göttingen have developed a new method to make biomolecules glow in real-time, eliminating unwanted signals in microscopy. This approach ensures only labelled biological molecules emit fluorescence, making experiments clearer and easier to interpret.
The new edition of the Wiley Registry of Mass Spectral Data 2026 expands compound coverage to over 915,500 reference spectra, strengthening a foundational layer of scientific data and research intelligence. This expansion enables researchers to identify unknown chemical compounds and materials faster with confidence.
Complex systems exhibit emergent properties due to water's unique polarity, enabling DNA to store information and proteins to adopt specific structures. This order forms the basis for complex molecules to develop unpredictable properties, driving the evolution of life.
Researchers identify previously unknown 'in-between' materials that can be used to design better solar fuels, batteries, and catalysis materials. The study reveals a series of hidden intermediate stages during heating, opening up new opportunities for material discovery and development.
Wagner's research aims to bridge the gap between molecular structure and mechanical properties, using machine learning to analyze entanglements in polymer chains. This could lead to designing more effective biomimetic tissue implants and other cutting-edge biomedical devices.
Researchers develop substrate design strategy to selectively promote benzidine-type sigmatropic rearrangement of nitroarenes, enabling efficient synthesis of polyfunctionalized biaryls. The method achieves high yields without expensive transition-metal catalysts or complex prefunctionalization.
Researchers discovered that strokes cause a chain reaction within the brain, leading to neuronal cell death. They found that blocking collagen production can prevent this damage and even restore motor function in paralyzed monkeys. The new drug KDS12025 reduces hydrogen peroxide levels and prevents the entire process from being triggered.
A new framework, Synthegy, combines established search algorithms with artificial intelligence capable of interpreting chemical strategies expressed in natural language. This allows chemists to express their goals in plain language and receive strategically relevant solutions.
A new EU project study found that combined exposures to man-made chemicals can lead to measurable biological effects not explained by individual substances, underestimating overall risk. The research identified a continuous exposure pathway from environment to people, including breast milk and umbilical cord blood.
Wiley has released additional data to its IR and Raman spectral libraries, significantly broadening compound coverage. The new release includes mineral spectra from the American Museum of Natural History, supporting researchers in making informed scientific decisions.
Researchers at University of Wisconsin-Madison develop a systematic study for sustainable production of malonic acid via oxidation of 3-hydroxypropionic acid with a Pd/Carbon catalyst. The kinetic model validated the network, displaying excellent agreement and providing insight into conditions that maximize MA production.
Researchers have finally understood why reinforced rubber is so tough and durable, with tiny particles forcing the material to fight against its own incompressibility. This breakthrough could improve tire design and lead to safer, longer-lasting products.
A team of researchers from Pohang University of Science & Technology has identified the underlying cause of water's unique properties, solving a fundamental mystery in science. They have observed water's liquid-liquid critical point, which marks the transition from two distinct liquid states into a single supercritical liquid state.
A new study by researchers at the University of California, Davis found that breathing in common disinfectant chemicals known as QACs can be far more harmful than swallowing them. The study suggests higher health risks for respiratory diseases such as asthma and COPD from airborne exposure to disinfectant sprays and cleaning products.
A University of Michigan study suggests that scientists wearing nitrile and latex gloves while measuring microplastics may overestimate the amount of tiny pollutants in air, water, and samples. The researchers recommend using cleanroom gloves instead to minimize contamination with stearates.
Researchers redesigned a key component of lipid nanoparticles to steer particles toward lymph nodes, reducing off-target delivery. This advancement could make mRNA vaccines more efficient, potentially achieving strong immune protection at lower doses.
Researchers develop oxychar, a highly efficient, budget-friendly alternative to traditional charred organic materials for toxic cadmium removal. The new material soaks up both agricultural ammonia and cadmium, promising a practical win for sustainable farming.
Researchers developed a method to use PFAS to extract lithium from high-salinity brine pools, reducing environmental damage and costs. The process, which uses electrothermal heating, recovers 82% of lithium fluoride at 99% purity, outperforming traditional methods in terms of energy efficiency and water usage.
The 2026 release expands coverage of emerging novel psychoactive substances, including synthetic cannabinoids, fentanyl analogs, and pharmaceutical drugs. The database provides comprehensive and up-to-date support for forensic, toxicology, and drug surveillance workflows.
Researchers developed a new catalyst strategy that uses BaSi2 as a support for nickel and cobalt to decompose ammonia at lower temperatures. This enables high hydrogen-production activity at reduced temperatures, matching the performance of ruthenium while relying on Earth-abundant metals.
Researchers have developed a new chemistry-based strategy to localize therapeutic drugs to tumors, reducing harm to healthy tissues. The 'lock-and-key' system uses biorthogonal supramolecular chemistry to release drugs in specific locations, offering a potential path to safer and more precise cancer treatment.
Research by University of Missouri scientists found that road salt is deadly to freshwater snails when paired with the presence of predators, causing nearly 60% higher mortality rates. The study suggests practical solutions to reduce salt pollution in waterways, such as cutting road salt use by up to 50%.
The B-STING silica nanocomposite acts as a nanofactory of reactive oxygen species, activating itself in response to changes in the chemical environment. This material can be used to create biocidal coatings that are safe, durable, and resistant to dirt, with potential applications in medicine and other industries.
Researchers discovered that a significant drop in calcium levels in the ocean led to a massive decrease in carbon dioxide, driving global cooling and ending the planet's greenhouse era. The study suggests that changes in seawater chemistry played a key role in shaping climate history.
A preclinical study shows that cannabidiol restores emotional behavior, reduces alcohol-related vulnerability, and reverses gut microbiota alterations caused by prenatal alcohol exposure. Female mice particularly benefited from CBD treatment, which normalized their emotional alterations and eliminated vulnerability to alcohol addiction.
MIT Energy Initiative researchers developed the largest combined dataset on global ammonia supply chains, examining economic and environmental impact of different scenarios. The study found that a full transition to clean ammonia production could cut greenhouse gas emissions by nearly 71% for a 23.2% cost increase.
Scientists developed a cost-effective method to produce 3-Hydroxypropanoic acid (3-HP), an industrial chemical used in disposable diapers, microplastics, and acrylic paint. The new process using engineered microbes to ferment plant sugars into 3-HP has been validated for commercial potential.
Researchers at Illinois Tech developed a new material with high ionic conductivity and low activation energy, enabling the efficient storage and release of energy. The material's unique structure allows lithium ions to move freely, even at cold temperatures, making it promising for applications in electric vehicles and energy storage.
A new digital and legally binding fingerprint developed at the University of Copenhagen makes products impossible to counterfeit. Royal Copenhagen is among the first brands in the world to use this solution, resulting in immediate transparency across their distribution chain.
Southwest Research Institute has upgraded its nuclear magnetic resonance (NMR) laboratory to provide robust chemical analysis of organic compounds used in drug discovery and development. The new facility enables rapid and cost-effective analysis using qNMR, which can be more efficient than HPLC for certain applications.
The Nanalysis Edition of KnowItAll combines Wiley's analytical software platform with Nanalysis' specialized NMR database, streamlining spectral interpretation workflows for users. The tailored solution provides immediate access to reference spectra optimized for benchtop NMR instruments, expanding compound identification coverage.
Researchers develop experimental drugs that encourage mitochondria in cells to work harder and burn more calories. The findings offer a framework for designing safe and effective weight-loss treatments with potential benefits for metabolic health and neurodegenerative diseases.
Chonnam National University scientists use an engineered enzyme to convert formaldehyde into L-glyceraldehyde, a valuable chiral C3 compound. The novel approach demonstrates how enzyme engineering can turn pollution into useful building blocks for medicine and industry.
Scientists have synthesised a new class of materials called state-independent electrolytes that allow negatively charged ions to move freely in solid and liquid states. This discovery opens possibilities for safer, lightweight solid-state devices with potential applications in batteries, sensors, and electrochromic devices.
Researchers developed a novel bioelectronic material that transforms from a rigid film to a soft, tissue-like interface upon hydration, enabling seamless integration with living tissues. The device, called THIN, has been shown to record biological signals with high fidelity and stability in animal experiments.
Researchers at Hokkaido University developed an environmentally friendly method to synthesize organosodium reagents using ball-milling mechanochemistry. This approach replaces traditional methods using highly reactive and toxic materials, offering a sustainable alternative in organic synthesis.
Researchers from POSTECH found that aluminum reduces internal structural distortion in cathodes, preventing oxygen holes and shortening battery life. By adding a small amount of aluminum, the team extends battery lifespan while improving energy density.
A study conducted at the University of California, Riverside, has uncovered a link between soybean oil consumption and obesity in mice. The research found that a genetically engineered group of mice on a high-fat diet rich in soybean oil did not gain weight, suggesting that the liver protein HNF4α plays a crucial role in fat metabolism.
Scientists at NRL and FIU create a new method for detecting trace levels of fentanyl without direct contact using a silicon nanowire array. This breakthrough offers first responders a faster, safer way to identify fentanyl and its related synthetic opioids.
Wiley has expanded its spectral libraries with major updates to IR, Raman, and LC-MS collections, delivering researchers enhanced capabilities for faster and more confident compound identification. The expansion brings over 9.5 million high-quality spectra, including 1 million IR spectra and 161,000 Raman spectra.
Researchers at MIT have developed a nearly impermeable polymer film that could protect solar panels and infrastructure from corrosion. The film, made using a solution-phase polymerization reaction, completely repels nitrogen and other gases, outperforming existing polymers.
Researchers at the University of British Columbia have identified eight per- and polyfluoroalkyl substances (PFAS) in B.C. sea otters, with concentrations three times higher on average in otters near major cities and shipping routes. This proximity effect highlights the need for government regulation to prevent PFAS spread.
Scientists at OIST have created crystal-free films of photoluminescent compounds that exhibit mechanoluminescence when stimulated through mechanical forces. This breakthrough removes the need for complex crystal design and engineering in creating mechanoluminescent materials.
Lehigh University researchers are collaborating with Dow on a three-year NSF-funded project to understand the chemistry behind full degradation of these polymers. The goal is to develop strategies for selective mixing of microbial communities to target different parts of the polymer for complete breakdown.
A new study reveals that the strength of carbon monoxide adsorption energy relies on a mix of reaction factors, including catalyst material and voltage. This insight can guide the design of more efficient catalysts to convert CO2 into useful fuels like methanol and ethanol.
Researchers from Newcastle University and the University of Birmingham developed a low-energy, waste-free method to recycle Teflon by breaking down its strong carbon-fluorine bonds into harmless sodium fluoride. This process has significant implications for reducing environmental pollution and promoting sustainable fluorine chemistry.
Researchers create novel compounds that kill bacteria in a new way, reducing the risk of side effects and environmental harm. The compounds have been shown to be effective in preventing bovine mastitis without affecting milk quality.
An AI-driven irrigation management system developed by Texas A&M University students uses soil sensors, crop data, and weather forecasts to optimize watering. The system conserves water, reduces costs, and increases crop yields, addressing global issues of water scarcity and inequity.
Researchers discovered how individual MXene flakes behave at the single-flake level, revealing changes in conductivity and optical response. The new spectroscopic micro-ellipsometry technique allowed for non-destructive measurements of individual MXene flakes, providing fundamental knowledge needed to design smarter technologies.
Scientists have found new complex organic molecules spewing from Saturn's moon Enceladus, confirming that complex chemical reactions are taking place within its underground ocean. The discovery strengthens the case for a dedicated European Space Agency (ESA) mission to orbit and land on Enceladus.
Researchers discovered bulky amino acids reduce pore size, blocking transport of certain molecules in aquaporin 10.2. This provides a framework for predicting functions of uncharacterized aquaglyceroporins.
Researchers at CARS create detailed maps of chemical reactivity, discovering regions of unexpected outcomes and reconstructing intricate reaction networks. This new understanding enables control over the formation of different major products from a set of starting materials.
A team of researchers developed a new manufacturing process using bio-based solvents to reduce the production cost of perovskite solar cells by half and decrease climate impact by over 80%. AI-based reverse engineering technology was used to identify optimal conditions for efficiency and sustainability.
A new way to produce ammonia more efficiently has been discovered by boosting its production using low-temperature plasma. This method could create ammonia in smaller facilities closer to where it is needed, making it safer and easier to transport, and potentially leading to a transformative change in energy storage and transportation.
The Alliance for Clinical Trials in Oncology will host a public webinar showcasing key findings from the 2025 ASCO Annual Meeting. Researchers will discuss latest information on colorectal, squamous cell, and renal cell cancers.
A new study has revealed chemical signatures of ancient Martian microbial life in the Bright Angel formation, a region of Jezero Crater known for its fine-grained mudstones rich in oxidized iron and organic carbon. The findings suggest that early microorganisms may have played a role in shaping these rocks through redox reactions.
Advanced filtration systems can cut levels of cancer-causing DBPs, nitrates, and heavy metals, in addition to removing toxic PFAS from drinking water. The Environmental Working Group study found significant reductions in these contaminants across 19 US utilities.