Articles tagged with Cancer Research
A University of Waterloo study uses mathematical modelling to explore how Vitamin C affects digestion-related cancer risk. The research suggests that consuming Vitamin C-rich foods like leafy greens may decrease cancer risk, while taking supplements after meals could have a moderate positive effect.
The National Comprehensive Cancer Network has launched a new version of its Distress Thermometer and Problem List in over 70 languages to screen patients for mental, physical, social, or spiritual distress. The tool aims to enhance cancer care by identifying psychological distress and providing support.
A study identified key tumor microenvironment features that can predict immunotherapy response in rare cancers, offering new insight into treatment options. The findings suggest that analyzing the tumor microenvironment beyond genomic analysis may help improve treatment selection for patients with rare cancers.
The University of Texas MD Anderson Cancer Center has been awarded $19 million by CPRIT to support young cancer survivors, groundbreaking research, and faculty recruitment programs. The funding will enable UT MD Anderson to recruit world-class scientists and clinicians, pursue new discoveries, and accelerate cancer treatment advancements.
Researchers at the Francis Crick Institute have discovered that sensory nerve signals interfere with the immune system's response to lung cancer. They found that exposure to cigarette smoke further exploits this neuroimmune interaction, accelerating tumour growth in mice.
A new mRNA-based strategy amplifies the T-cell response to vaccines, enabling more powerful cancer vaccines and stronger protection against infectious diseases. The approach reprograms immune cells from within using mRNA instructions that expand cancer-fighting T cells.
Dr. Sandra Orsulic has received two federal awards totaling nearly $2 million to advance research aimed at improving outcomes for women with ovarian cancer. Her team will examine the body's inflammatory response after surgery and develop AI-powered tools to guide personalized treatment.
Four new OICR-funded studies using CATALYST will advance cancer insights by reanalyzing existing patient samples and data. The initiatives aim to improve cancer detection, diagnosis, and treatment by building on previous research.
A rare case of high-grade laryngeal leiomyosarcoma was successfully treated with extended laryngectomy, left neck dissection, and adjuvant chemotherapy. Complete surgical excision remains the cornerstone of therapy, while multidisciplinary-guided adjuvant treatment may benefit selected high-grade or high-risk patients.
At ASCO 2026, City of Hope experts will present research on innovative treatments for various types of cancer. Their findings include the efficacy and safety of immunotherapy combinations, as well as the potential use of CBM588 to enhance immune checkpoint blockade in metastatic renal cell carcinoma.
A new editorial proposes the use of agentic AI systems to address cancer-related malnutrition, a prevalent issue affecting up to 80% of patients. These systems aim to coordinate multiple functions simultaneously and support ongoing clinical decision-making throughout treatment.
The summit brought together endocrine leaders to identify opportunities to work closely together on increasing the visibility of endocrine health in policy decisions. Early findings from a workforce survey revealed challenges including long patient waiting times and retention concerns among early-career clinicians.
Glioblastoma is a highly aggressive brain tumor that has seen modest improvements in survival rates over the past decade. Researchers at UCLA's Jonsson Comprehensive Cancer Center are part of a national effort to develop more personalized approaches to care, combining advanced imaging and analysis of tumor tissue samples and blood test...
A rare case of a small bowel GIST harboring concurrent KIT exon 9 duplication and SDHC mutation showed a strong response to high-dose imatinib, despite the presence of the SDHC mutation. Integrated molecular interpretation is crucial in GIST management.
The study identifies nine distinct cellular neighborhoods in the tumor microenvironment, each associated with survival and immunotherapy response outcomes. The blood-based liquid biopsy test could guide treatment decisions for multiple cancer types and treatments.
Researchers at the Sylvester Comprehensive Cancer Center presented several studies at ASCO 2026 exploring new treatment options for patients with advanced gastrointestinal stromal tumors (GISTs) and melanoma. These include velzatinib, a targeted therapy for GIST patients, and PRAME-directed T-cell receptor therapies for synovial sarcoma.
Three young scientists in Israel have been awarded the prestigious Blavatnik Awards for their innovative research in chemistry, cancer biology, and astrophysics. Sergey Semenov, Uri Ben-David, and Paz Beniamini will each receive US$100,000 to advance their projects on complex materials, cancer treatments, and extreme cosmic events.
Dr. Aparna Bhaduri receives $750k Pershing Square Sohn Cancer Prize for her innovative glioblastoma research. Her advanced human organoid models reveal how tumors interact with the immune system and brain cells, driving tumor aggressiveness.
The UK-led OpenBind initiative has released its first publicly available dataset and predictive AI model, accelerating the discovery of new medicines using artificial intelligence. The release showcases high-quality, standardized experimental data and a trained predictive model, enabling researchers worldwide to drive the next generati...
Researchers at UT MD Anderson Cancer Center have made significant advancements in targeted therapy treatments for advanced lung cancer and early-stage classical Hodgkin lymphoma. The studies showcase high response rates with novel combination therapies and a new understanding of how an enzyme affects infertility and cancer progression.
Volume 39 of SLAS Discovery highlights novel assays and AI-assisted workflows to accelerate personalized cancer immunotherapy. The journal aims to advance life sciences discovery through education, knowledge exchange, and global community building.
A new study found a clear shift in mortality trends in multiple myeloma closely parallels major therapeutic advances. Targeted therapies, including immunomodulatory drugs and CAR T-cell therapies, have significantly improved disease control and induced deep responses.
Researchers at UTHealth Houston have discovered a new target for metastatic breast cancer treatments using experimental peptide therapy. The study found that the peptide BLMP6 targets fibulin-4, a protein expressed in high levels in metastatic breast cancers.
Researchers developed tiny flexible lasers that can measure forces inside living cells, enabling insights into biological processes such as early development and tumor progression. The micro-lasers exhibit mechanical stiffness similar to living cells and can measure forces up to 50 nanonewtons.
The state of Utah has invested over $33 million in artificial intelligence and computing initiatives to advance health and discovery. The investments will enable a new AI supercomputer accessible to all state universities, accelerating breakthroughs in prevention, early detection, personalized treatments, and survivorship across numero...
A specific region of Dicer must be activated to achieve proper cell division and reproduction, a discovery that sheds light on the regulation of this enzyme's critical role in both cancer biology and fertility. This finding opens new avenues for studying how small epigenetic changes contribute to disease.
Researchers developed RF-SIRF, a quantitative method to detect and map reversed DNA replication forks with single-cell resolution. The study identified unique epigenetic codes for DNA replication stress that can be further examined to understand genomic stability, aging, and treatment response.
A new study from Tulane University found that extra sets of chromosomes in tumor cells make them more mobile and likely to engulf neighboring cells. This stress response triggers an abundance of proteins, reprogramming the cells for motility and phagocytosis.
Researchers found that disruption of communication between cancer-causing cells and surrounding healthy tissue can prevent tumor growth. The study suggests that early intervention may be possible, as the transformed environment is reversible if caught early enough.
A rare case of mucinous ovarian carcinoma was reported in a postmenopausal woman, initially misdiagnosed as a pelvic abscess due to nonspecific symptoms and radiologic features. The diagnosis was confirmed after advanced imaging and tumor marker assessment. Early recognition is crucial for timely diagnosis and effective treatment of th...
MSK researchers showcased innovative therapeutic advances for HER2-driven rectal and KRAS-driven pancreatic cancers, as well as a promising mRNA vaccine. CAR T cell therapies targeting uPAR showed promise in shrinking solid tumors and overcoming treatment resistance.
Five fellows will receive funding for four years to study hard-to-treat pediatric cancers, reduce treatment toxicity, and develop innovative therapies. Their research focuses on Ewing sarcoma, leukemia, kidney cancer, and immune system vulnerabilities.
A study found that early myocarditis onset after immune checkpoint inhibitor therapy significantly increases the risk of death from treatment-related causes. Patients who developed co-occurring myositis and myasthenia gravis were also at a higher risk, with some cases leading to fatal outcomes.
Dr. Aditya Bardia has been elected to the American Society for Clinical Investigation for his outstanding contributions to research and patient care in breast cancer treatment. He is advancing precision medicine therapies through antibody-drug conjugates and liquid biopsy technologies.
A new study found that cancer types with high lethality receive lower federal research funding, prioritizing these cancers could help direct resources to diseases with greatest potential to reduce suffering. Additionally, certain cancers have a disproportionate impact on underserved populations and quality-of-life burden.
The KIR-CAR T cell therapy has shown promising results in a Phase I clinical trial, demonstrating safety and increasing efficacy with higher doses. The treatment targets mesothelin, widely expressed on several solid tumor cancers, and limits side effects through its natural 'on-off' mechanism.
The Phase I MYTHIC trial demonstrated a strong synergy between zedoresertib and lunresertib, showing durable regressions and consistent tumor shrinkage in patients with ovarian cancer. The combination achieved an overall disease control rate of 68.5% and a molecular response rate of 47%.
A new single-chip camera captures ultraviolet, near-infrared and visible images using a compact design inspired by the multiwavelength vision capability of the mantis shrimp. The camera helps surgeons identify cancer-linked lymph nodes during surgery, making cancer treatment safer and less invasive.
A rare scalp reaction resembling erosive pustular dermatosis was identified in a lung cancer patient treated with amivantamab following cranial radiotherapy. The reaction appeared to be related to impaired wound healing due to dual inhibition of EGFR and MET signaling pathways.
Researchers identified a CRISPR variant that distinguishes tumor DNA from healthy DNA and selectively cuts the former. This method relies on methyl groups attached to DNA, which are altered in cancer cells.
A recent study published in Cell reveals the molecular mechanisms underlying the transformation of benign pancreatic cells into malignant tumors. Researchers identified a subset of precancerous cells that closely resemble tumor cells, characterized by high oncogenic drive and strongly activated tumor-suppressors. This discovery offers ...
Researchers from UT MD Anderson Cancer Center present studies on single-cell technologies, integrative computational approaches, and experimental therapeutics, highlighting innovations in mRNA vaccines and spatial multi-omics techniques. The studies aim to improve immunotherapy responses and detect treatment-resistant glioma cells.
A University of Calgary-led study found that multiple myeloma tumour cells adapt in multiple ways to become resistant to treatment, highlighting the need for personalized cancer therapy. The research aims to develop next-generation treatments designed to anticipate and overcome these changes.
Researchers from Penn Medicine will showcase progress in CAR T cell therapies for solid tumors, as well as a multi-chain CAR T cell therapy for ovarian cancer. The presentation also highlights a new strategy targeting pancreatic cancer before it forms and at-home cervical cancer testing.
The Marlene and Stewart Greenebaum Family Foundation donated $5.5 million to the University of Maryland Greenebaum Comprehensive Cancer Center to fund groundbreaking scientific research and compassionate cancer care. The funds will support innovative treatments, including immunotherapies, and strengthen support for cancer survivors.
The American Association for Cancer Research (AACR) is recognizing Senator Susan Collins and Jill Feldman with the 2026 Distinguished Public Service Award and Distinguished Patient Advocacy and Engagement Award, respectively. Collins received the award for her strong support of medical research funding through the National Institutes o...
The American Association for Cancer Research (AACR) has recognized exceptional cancer journalists with the 2026 June L. Biedler Prize. The prize winners showcased remarkable ability to communicate complex scientific concepts in clear language. Their stories enhanced public understanding of cancer, science, and advocacy.
The American Association for Cancer Research (AACR) has recognized three researchers with the 2026 Scientific Achievement Award: James Allison, for his pioneering work on CTLA-4; John DiPersio, for his advances in leukemia and stem cell biology; and Jane Arrowsmith, for her contributions to chemical biology and cancer epigenetics. The ...
The foundation named 13 new Damon Runyon Fellows and six recipients of the Damon Runyon-Dale F. Frey Award for Breakthrough Scientists, awarding them a total of $4.5 million to investigate various aspects of cancer research. The awards recognize promising young scientists conducting basic and translational cancer research.
A team of researchers from Mass General Brigham found that sialylated CD43 forms a glyco-immune barrier restraining anti-leukemic immunity. This suggests therapies targeting CD43 could be promising for treating AML and potentially a broader range of cancers.
Nancy L. Lewis, MD, MBS, FACP, a renowned biomedical researcher and clinical trials expert, has been appointed as the new Chief Scientific Officer of the National Comprehensive Cancer Network (NCCN). She will oversee NCCN's programs to advance clinical trials and improve cancer care outcomes globally.
UCLA investigators present new research on targeted drug delivery for colorectal cancer, COVID-19's impact on breast cancer outcomes, and AI in cancer diagnosis. These studies offer insights into overcoming drug resistance, enhancing immune responses, and improving outcomes for patients with difficult-to-treat cancers.
Researchers at UT MD Anderson have made significant advancements in cancer care, including a blood-based biomarker for cancer risk in people with Lynch Syndrome and a new target to sensitize pancreatic tumors to immunotherapy. The studies also identified a strategy to overcome radiation therapy resistance in lung cancer.