Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
Researchers have resolved the atomic-scale interplay between hole transfer dynamics and water oxidation intermediates on faceted BiVO₄ particles. A critical hole density threshold dictates pathway bifurcation, with the (010) facet becoming catalytically superior above this threshold.
Researchers at Rice University developed a custom Python-based software tool to rapidly analyze data from high-resolution X-ray diffraction, identifying dislocations and irregularities in the atomic lattice. The approach can accelerate the development of more reliable electronic and quantum devices.
The study found that sepsis continues to be a significant cause of mortality in China, with infections accounting for the majority of deaths. The analysis also revealed age-related differences in sepsis burden, with older adults and males consistently carrying the highest risk.
A new study by Flinders University reveals that targeting specific pain receptors in the bladder can reduce debilitating effects of cystitis. The research suggests that activating certain cannabinoid receptors could provide relief from bladder pain and urinary urgency associated with interstitial cystitis/bladder pain syndrome (IC/BPS).
A team of researchers extracted and analyzed protein fragments from fossil teeth of Homo naledi, finding zero male markers. This discovery suggests a sex-bias in mortuary practice among non-human species, unlike observed in contemporary human cultures.
The Mount Sinai Adolescent Health Center has received the 2026 Community Health Improvement Award from HANYS, recognizing its decades-long leadership in comprehensive, confidential, equitable care for adolescents and young adults. The award honors the Center's commitment to improving public health and advancing health equity.
Researchers discovered a combination regimen of two β-lactam antibiotics resulted in faster and greater killing of bacteria than using each antibiotic alone. The pairing suppressed resistance to both antibiotics, offering a promising approach to optimising and personalising antibiotic regimens against life-threatening infections.
Researchers developed a new catalyst that accelerates water dissociation and hydrogen adsorption, enabling faster hydrogen evolution reaction activity and stronger stability. The study presents a TiO₂ QDs/Co₃O₄ symbiotic oxide support that precisely regulates Pt clusters for alkaline hydrogen production.
A team of researchers from Science Tokyo has developed a new method to reversibly switch the chirality of semiconductor materials using electrochemistry. This innovation enables the creation of spin-polarized currents in layered non-chiral semiconductors, opening up new directions for developing ultrafast and energy-efficient devices.
Jorge Íñiguez-González leads a €2.5M ERC Advanced Grant project to explore reconfigurable materials with tunable properties. The research aims to create adaptive technologies for information storage and next-generation computing.
Researchers developed an AI framework to identify viable target antigens for CAR T cell therapy, using publicly available single-cell RNA sequencing data. The framework showed robust tumor-killing activity in mouse models of multiple cancer types, including melanoma, leukemia, and colorectal cancer.
A Brazilian study found that 86% of children and adolescents with musculoskeletal pain recover, but 32% experience recurring pain. The study identified factors such as quality of life and age as predictors of recovery.
Researchers identified a distinct fibrotic fibroblast population in hypertrophic scars, which they linked to the transcription factor Yin Yang 1 (YY1). Restoring YY1 expression reduced scar-associated fibroblast activation, providing new insights into scar fibrosis and potential therapeutic strategies.
A cohort study found that a dietary pattern with lower inflammatory potential was associated with lower dementia risk among individuals with Alzheimer disease pathology. Targeted dietary strategies may help prevent dementia in those already at elevated risk.
A new study identifies key degradation mechanisms in perovskite solar cells, including phase segregation, copper corrosion, and edge patterns. Accelerated aging tests can accelerate these processes, but may not reflect real-world degradation.
The TREM-1 receptor amplifies innate immune responses and is a promising therapeutic target for inflammatory diseases. The review highlights its pathogenic roles in acute systemic inflammation and chronic conditions like inflammatory arthritis and neurodegenerative disorders.
The Sports Heat Tool, developed at the University of Sydney, provides personalized heat risk assessments for various sports. Users can input their location and chosen sport to receive a heat-risk score and practical steps to mitigate risks, taking into account factors such as temperature, humidity, and exertion.
A genome editing technique called base editing has been used to study the role of a master gene in human embryonic cells, revealing its crucial function in early development. The technique allows scientists to alter a single gene in human embryos, enabling them to better understand how human embryos develop.
Scientists at Universitatsklinikum Bonn developed a robust laboratory method to generate and study follicular regulatory T cells. The research found that TGF-β and IL-2 signaling pathways control the development of these cells, which regulate immune tolerance and antibody responses.
A team of scientists observed Jahn–Teller polarons in cobalt oxide crystals activated by tailored laser pulses. The study reveals the material's structural, electrical, and magnetic properties can be engineered using ultrafast laser pulses.
A study reveals that the rhythmic structure of laughter has remained constant in all living great apes, including humans, for at least 15 million years. This finding offers unexpected clues to the evolution of human speech, suggesting that sophisticated vocal control is a fundamental building block.
The Political Ecology Network will convene its biennial international conference POLLEN 2026 in Barcelona, Spain, from June 29 to July 3, 2026. The event will bring together researchers, activists, and creators to discuss contemporary crises and forge pathways toward peaceful alternatives.
Researchers found that puerarin significantly ameliorated serum biochemical abnormalities and histological changes associated with cholestatic liver fibrosis. The treatment promoted conjugation of hydrophobic bile acids into more hydrophilic forms, suggesting enhanced hepatic detoxification capacity.
Large language models can accurately identify reasons for medication discontinuation from doctors' electronic clinical notes, revealing that adverse reactions are a common cause. The study uses this approach to transform clinical free text into analyzable data, supporting evidence-based decision-making in health policy.
A new Cornell University study examines the relationship between cranial shape and body weight in dogs, identifying a link to syringomyelia, a painful spinal condition. Breeds prone to syringomyelia exhibit distinct skull shapes, highlighting the need for breed-specific treatment strategies.
Researchers at King's College London have developed an AI model that can improve a Formula One team's finishing position in simulations of the 2023 Bahrain Grand Prix. The model, which uses reinforcement learning and explainable AI, outperformed existing race strategy optimization techniques in many cases.
Researchers found that a daily spermidine supplement improved immune response to COVID-19 vaccination in older adults. Spermidine reduced markers of immunosenescence and stimulated autophagy, leading to higher antibody levels and better neutralizing activity against multiple viral variants.
Emerging evidence positions lactylation as a critical metabolic-epigenetic hub in lung cancer. Lactylation drives oncogenic programs and immune-evasion pathways, contributing to treatment resistance. Targeting this axis may restore treatment sensitivity.
A new study finds that young people from lower-income countries with limited internet access are at risk of being overlooked for mental health support due to climate change. This exclusion skews the evidence base, failing to adequately address the needs of those most affected by climate-related anxiety and depression.
Artificial intelligence is being harnessed to integrate multi-omics data from large-scale repositories such as TCGA and GDSC to decode tumour drug resistance. The review advocates for explainable AI frameworks, multimodal fusion strategies, and dynamic liquid-biopsy monitoring to address barriers to clinical adoption.
Researchers identified miR-29a as a pivotal regulator of cancer development, which can act as both a tumor suppressor and an oncogene. Natural bioactive compounds such as curcumin, EGCG, and resveratrol have been shown to restore normal miR-29a expression through epigenetic remodeling and inhibition of oncogenic signaling pathways.
A new study reveals rooftop solar panels can offset nearly half of increased electricity demand during peak cooling periods. Climate change alone is projected to push up residential cooling demand by 5%, but rooftop solar growth could halve this additional load, easing pressure on the grid.
Global newborn mortality from birth asphyxia and trauma has declined, but progress is slowing in low- and middle-income countries, particularly in sub-Saharan Africa. Countries with lower scores on human development indices experienced slower mortality declines, highlighting the need for targeted investments to close the equity gap.
A new prodrug and localized drug delivery platform have been developed by researchers to selectively target cancer cells. The platform uses carbamate masking of the 4-anilinoquinazoline hinge nitrogen to modulate exposure and enable controlled activation of EGFR-TKIs in tumour microenvironments.
A new artificial lateral-line sensing unit helps underwater robots estimate both magnitude and direction of local flow velocity. The sensor uses a flexible silicone spring, light-emitting diode, and photodiodes to detect subtle hydrodynamic changes in water flow.
Gramine, a natural indole alkaloid, exerts potent anti-tumor effects against triple-negative breast cancer (TNBC) by inducing ferroptosis. The compound selectively targets TNBC cells while sparing normal mammary epithelial cells.
The probiotic strain Lactobacillus rhamnosus CMU-pb-7 improves DN rats' condition, reducing total cholesterol and triglycerides. It reverses renal interstitial fibrosis and restores antioxidant capacity by activating the Nrf2/HO-1/Gpx4 pathway.
Research suggests that inhaled vitamin D can protect against dust, pollution, and pathogens in the lungs, potentially improving outcomes for those with chronic lung disease. Human clinical trials are needed to confirm these findings and explore the therapeutic benefits of direct lung delivery.
Researchers developed a frequency-domain thermoreflectance microscopy approach to visualize thermal conductivity and interfacial thermal conductance in thermal interface materials. The study reveals pronounced microscale heterogeneity, with high- and low-conductivity zones observed in particle-loaded thermal greases.
A recent study identified fPRDM16 as a potential therapeutic target for pulmonary fibrosis, linked to the decline of collagen-clearing capacity in lung fibroblasts with age. Restoring youthful levels of fPRDM16 may offer a promising approach to reverse persistent fibrosis.
Two new policy briefs support evidence-based decision-making in EU environmental policies, including the Nature Restoration Regulation and Biodiversity Strategy 2030. The briefs provide a framework for monitoring ecosystem pressures and recovery across the European Union.
Mayo Clinic researchers have identified a previously hidden step in the immune system's preparation to fight cancer, suggesting that the thymus plays a crucial role in training T cells before they enter circulation. This discovery could lead to more effective and longer-lasting cancer immunotherapies.
Researchers developed a new methodology to identify biomarkers for male infertility, enabling comprehensive analysis of lipids and metabolites. They found 955 potential metabolites and 473 lipids that could be present in sperm.
Researchers at Linköping University found that old oak trees and semi-natural grasslands are crucial habitats for many species. The study identified thresholds for habitat size needed to support species survival, providing conservationists with concrete data to prioritize cost-effective interventions.
A study found that supplementing with HMB before surgery improves liver regeneration in animals by preserving energy function and improving the quality of recovery. The supplementation was shown to have a beneficial effect on mitochondrial function and metabolic performance, even after it was discontinued.
A recent study published in JAMA Otolaryngology–Head & Neck Surgery reveals a higher incidence of smell and taste disturbances among GLP-1 RA users. The findings underscore the importance of regular monitoring and awareness to mitigate these adverse effects.
Researchers developed a compact, cost-effective diagnostic platform combining lensfree holography and deep learning for automated HER2 scoring. The system reached 84.9% accuracy for four-level HER2 classification and 94.8% accuracy for binary scoring, effectively lowering diagnostic risks.
JMIR Publications invites submissions on the 2026 Ebola disease public health emergency of international concern, focusing on response strategies, risk communication, and surveillance. The World Health Organization has declared a public health emergency due to population mobility and ongoing uncertainty in the Democratic Republic of th...
A recent review highlights the pivotal role of lactate and lactylation in PDAC progression, including their function as alternative metabolic fuel, signaling molecule, and epigenetic regulator. Therapeutic strategies targeting lactate metabolism offer promise, but clinical translation faces significant hurdles.
Researchers found that bariatric surgery can lead to a significantly higher risk of developing alcohol problems. The altered anatomy affects how the body processes and absorbs alcohol, leading to faster intoxication and prolonged recovery times.
Researchers discover a novel mechanism where PVT1 and EIF4A1 drive gastric cancer metastasis through the Notch-1 signaling pathway, resulting in increased tumour cell migration, invasion, and proliferation. Elevated STC1 levels confirm its role as a key downstream effector of this axis.
Researchers at Hiroshima University report a remarkable decline in chronic HBV and HCV cases, from 3.0-3.07 million to 1.1-1.4 million between 2000 and 2020. Projections suggest the number of HBV infections will drop to around 200,000 cases by 2050, while HCV is estimated to decline to fewer than 20,000 cases.
The 2026 Warren Alpert Foundation Prize was awarded to five scientists who developed curative genetic therapies for two major blood disorders. These treatments, CASGEVY and LYFGENIA, have been approved by the FDA for use in the US and have shown significant advancements in the field of gene therapy.
Research finds that millennials' fear of growing up decreases as they age, while younger generations report higher maturity fears. The study, published by the American Psychological Association, suggests that broader societal factors such as economic uncertainty and social pressures shape how young people view adulthood.
Scientists have discovered a way to track whales using fiber-optic cables by detecting low-frequency pressure waves generated by their movement. This method allows researchers to identify whale tracks even when the animals are not vocalizing, expanding their capabilities for remote sensing applications.
A WSU study explores the environmental cost of influencer PR gifts, finding that only 1% of comments mention packaging sustainability. The research suggests influencers can promote eco-friendly behaviors by discussing sustainable practices in their unboxing videos.
A recent study evaluated the safety and effectiveness of the J-Valve Transfemoral System in treating symptomatic severe aortic regurgitation. The study showed sustained valve performance, meaningful symptom improvement, and evidence of reverse left ventricular remodeling at one year.
Researchers have uncovered a potential strategy to eliminate cancer cells that survive KRAS inhibition, preventing relapse. By targeting the metabolic pathways that support the survival of drug-tolerant persister cells, treatment regimens could be designed to shrink tumors and prevent cancer recurrence.
A study found that discussing from a third-person perspective in virtual environments improves consensus agreement, accuracy in understanding others' opinions, and reduces intragroup conflict. However, it also decreases emotional connection among participants.
A pilot study found that an examiner-worn, neck-mounted camera can supplement the observation and review of clinical skills during OSCE assessments. The results showed moderate to strong agreement between live and video-based assessments, with the wearable camera enabling more observations to be evaluated than the fixed camera.