Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
Researchers have developed a new AI-based method that can detect and classify brain tumors from MRI scans more accurately than traditional diagnostic systems. The system combines advanced AI models, including CNNs and LSTM networks, to achieve better outcomes.
Researchers have developed spatialproteomics, an open-source software package that makes it easier to analyze complex tissue images. This framework guides users from raw microscopy images through cell segmentation, annotation, and spatial analysis, standardizing workflows and enabling more efficient and reproducible results.
The IP4OS project challenges misconceptions about the conflict between IP and Open Science, highlighting their synergistic potential. The Role Model Campaign features diverse stakeholders sharing their experiences of navigating IP and Open Science together.
A new study found that a simple blood test can accurately identify tuberculosis (TB) among patients, which could help save millions of lives and reduce transmission. The test measures a specific marker called ESAT-6 produced by the TB bacteria.
The National Science Foundation has awarded Boston University $20 million to enhance its cloud lab, allowing researchers to request complex experiments remotely. The BU-based lab will focus on biotechnology and engineering biological systems, with the capacity to host studies on new vaccines, DNA sequencing, and genetic engineering.
A new pan-European study identified the psychological and contextual factors that shape decision-making among healthcare professionals. The findings provide important insights into how behaviour change frameworks could support the uptake of new treatments, with the strongest lever being to shift intention to prescribe.
Researchers from the University of Waterloo developed a new quantum sensing technique using a molecule as a sensor, enabling precise imaging of single molecules. This technique has potential applications in drug discovery and structural biology.
Researchers at IIT Gandhinagar develop faster, more specific and sensitive staining method for visualizing xylem, enabling stronger research on plant development, vascular biology and crop resilience. The new probes achieve strong fluorescence signals at lower concentrations than conventional dyes.
Researchers unveil a powerful strategy to enhance photocatalytic hydrogen production by manipulating linkage isomerism within covalent organic frameworks (COFs). COF-DPPQ achieves a 100-fold increase in catalytic performance, optimizing internal electric field and carrier lifetime. The study provides a generalizable paradigm for develo...
Circulating circRNAs show high cell-type and tissue specificity, making them ideal for non-invasive cancer management. They can be detected in multiple body fluids and reflect treatment response, positioning them as functional drivers of therapy resistance.
Researchers have developed a consensus-based framework and definitions for vocal biomarkers to improve collaboration and validation of voice-derived indicators in health conditions such as Parkinson's, Alzheimer's, depression, heart failure, and type 2 diabetes. The framework provides a scientifically grounded vocabulary to support the...
George Mason University Assistant Professor Xuan Wang will receive funding for his project on knowledge transfer in robot learning. He aims to develop efficient approaches that enable robots to reuse prior knowledge, supporting safer and more affordable robotic technologies in various industries.
A new clinical trial found that integrated early-life interventions significantly improved the growth and neurodevelopment of babies born too small. The study, conducted in India, showed a lower prevalence of underweight, stunting, and anemia among infants receiving the intervention.
The IOF Musculoskeletal Rare Diseases Training Course bridges latest scientific advances with current clinical guidance, covering disorders-specific programs. Clinicians can access high-quality educational content at their own pace to deepen expertise in rare skeletal conditions diagnosis and management.
Researchers at Tohoku University developed a method to restore the mechanical strength of degraded polybutylene terephthalate by repairing molecular chains with a chain extender. The technique recovers plastic tensile strength to nearly that of virgin material, enabling high-performance plastics to be reused instead of discarded.
A new immunotherapy treatment has been shown to be effective in treating high-risk bladder cancer, allowing many patients to keep their bladder instead of having it surgically removed. The treatment, called cretostimogene grenadenorepvec, produced a complete response in 75% of patients, with most side effects being mild and temporary.
The National Academy of Inventors and US Patent and Trademark Office announce a five-year national initiative to expand intellectual property education, accelerate commercialization, and unite America's innovation ecosystem. The partnership aims to strengthen America's invention-to-impact pipeline by uniting research, IP, entrepreneurs...
Researchers developed a mathematical model to reconstruct COVID-19 spread in Dutch schools, showing that targeted closures can reduce hospital admissions. The study highlights the value of mathematical models for informing public health decisions during outbreaks.
Researchers found that consistent daily routines lower pain and depression levels in older adults with insomnia. Maintaining a regular schedule helps synchronize the body's internal clock, leading to improved health outcomes.
Researchers at Baylor College of Medicine and Houston Zoo have developed the world's first mRNA vaccine against elephant endotheliotropic herpesvirus (EEHV), a deadly disease affecting young Asian elephants. The vaccine has shown promising results in clinical trials, providing protection against severe hemorrhagic disease.
Scientists have discovered a new approach to treating genetic brain disorders by redirecting brain development. The therapy helps at-risk neurons grow and connect more normally, strengthening connections among existing neurons and restoring cognitive function.
A new glioblastoma model called Core2Edge has been developed to study the invasive front and direct assessment of new drug candidates in human tissue. The model combines glioblastoma organoids with human brain tissue, allowing for the tracking of tumor cell spread and the visualization of fine structures.
A Phase 2 clinical trial shows that a THC/CBD combination significantly reduces agitation in hospice-eligible people with dementia. The study, conducted across multiple US sites, achieved its primary and key secondary endpoints, demonstrating the efficacy of this treatment approach for end-of-life agitation.
The University of Tennessee at Knoxville has signed a new six-year master research agreement with Eastman, investing $3 million to support sponsored research and university-industry initiatives. The partnership aims to advance materials innovation, develop talent, and create solutions that benefit communities.
New evidence from Malta reveals that hunter-gatherers engaged in repeated long-distance sea journeys of at least 100km between Sicily and Malta for at least a millennium. This suggests that the Maltese Islands were part of a hitherto unknown, sustained long-distance sea voyaging network.
A new carbon calculator, SPA-DEC, allows spas and wellness centers to measure emissions per visit in real-time. The calculator combines live data with normalized figures to allocate total emissions to individual visits across Scopes 1, 2, and 3 of the Greenhouse Gas Protocol.
A simple data-driven triage protocol has been developed to identify patients who can safely receive care in a seated treatment area, reducing emergency department length of stay by 11 minutes. The approach uses information already collected during triage and requires no additional staff or resources.
Researchers developed three functional components for photonic microchips using inverse design algorithms. The new components are up to 500 times smaller and more efficient than traditional designs.
Researchers have uncovered the identities of three kings omitted from the Assyrian King List, shedding new light on early Neo-Assyrian political history. The discoveries suggest that the AKL may not be an impartial chronographic work, but rather a legitimizing canon of kings used to remove short-lived or parallel rulers.
A new AI tool developed by La Trobe University researchers can analyze routine pathology slides to predict stage-two bowel cancer patients at risk of relapse. The study analyzed over 1600 pathology slides and validated the findings across 1220 patients in three independent cohorts.
Researchers at Kaunas University of Technology have developed a greener alternative for fire-resistant concrete using waste-based geopolymer mortars. These materials retain high compressive strength even after exposure to extreme heat, making them ideal for construction applications where high temperatures are present.
A new study by the University of Delaware has identified global hotspots of drought-sensitivity and resilience in major crops like rice, corn, and soybeans. These hotspots reveal areas particularly susceptible to drought, such as the Midwestern US, eastern Brazil, and northern India.
A research team has developed a dual-side electrosynthesis strategy to convert plastic and biowaste into succinic acid, a versatile four-carbon platform chemical. The new system achieved an apparent succinic acid yield of 169.1%, exceeding the theoretical limit of conventional single-electrode processes.
The SNU team developed a new nanostructured catalyst, termed 'nanomace,' by chemically bonding ceria nanocubes and nanorods. The interface where the two crystal structures meet serves as a key active site, enhancing lattice oxygen activation and catalytic reactions.
An observational study found that early remdesivir treatment reduced the risk of all-cause graft loss and cardiovascular events in adult kidney transplant recipients with COVID-19. The study included 432 participants, with 177 receiving at least three days of remdesivir therapy.
A case report describes a novel interventional approach for hepatic myelopathy, where paraspinal vein shunt embolization alleviated post-TIPS complications. The study suggests that venous compression may be the primary mechanism underlying HM pathogenesis.
A Curtin University study found that children who attend preschool before starting school are significantly more likely to arrive ready to learn. The study, which analyzed over 123,000 Western Australian children, also showed that preschool attendance was associated with better developmental outcomes across every area of child developm...
A new study reveals that USP22 regulates B-cell activation and differentiation through the CHD4-CD19 axis. Inhibiting USP22 partially reversed B-cell hyperactivation in Kawasaki disease patients.
A new study by Duke University researchers found that atmospheric rivers contribute to marine heatwaves, with a strong association in winter months. The team's analysis of satellite data revealed that active atmospheric rivers often precede peak marine heatwave temperatures, suggesting a causal link.
Researchers will investigate how impaired cellular waste-clearing systems contribute to Parkinson's disease. The collaboration aims to uncover mechanisms that could guide future therapeutic strategies, with a focus on understanding the role of lysosomes in disease development.
Researchers identify AXL as a previously unrecognized regulator of bone formation, promoting osteoblast maturation and increasing bone mass. Inhibiting Axl using BGB324 increases bone growth in mice without significant toxicity.
A new study introduces a novel approach to personalized learning resource recommendation, treating resources as part of an intricate knowledge network. The Unified Learning Resource Recommendation Method (ULRRM) integrates multidimensional graph information to deliver accurate and context-aware recommendations.
A new study from the University of Sussex reveals that neural responses are surprisingly low for large numbers of lives at risk and for lives lost overseas. The study found an inverted U-pattern response across the number of lives at risk in countries abroad, with a unique pattern for overseas lives.
Researchers at EPFL have developed a new quantum readout architecture that achieves fast and accurate qubit measurements with fewer additional components, allowing for improved performance and reduced hardware footprint. The new design uses a Josephson junction to provide built-in protection against information loss during measurement.
A recent study found that human lung tissue contains a vast reservoir of tissue-resident memory T cells (T RM cells) capable of targeting a range of viruses, bacteria, and fungi. These cells reside only in the lungs and can live for years, providing a vital line of defense against severe respiratory infections.
New national standards recommend earlier screening and lifelong monitoring for development and cognition in individuals with SCD, aiming to reduce variability in care. The guidance, developed in collaboration with Children's Colorado, provides a tiered approach to care, including surveillance and evaluation.
Scientists develop a biomimetic coating mimicking human skin, combining superior water resistance with high-efficiency fire retardancy. The coating exhibits impressive mechanical durability and exceptional flame-retardant performance, including self-extinguishing capabilities.
A study in rats found that guava leaf extract significantly lowered fasting blood glucose levels and improved lipid profiles, including reductions in cholesterol and triglycerides. The extract also boosted antioxidant defenses and reduced oxidative stress, suggesting a potential therapeutic effect against diabetes-related complications.
Researchers developed a new formula for a hydrogel that can be printed in any shape or size, adhering to skin even when sweaty or hairy. The hydrogel also improved durability and electrical conductivity by adding graphene-based nanomaterials, making it a more potent sensor
The study integrates metasurfaces with photodetectors to create ultra-compact, multi-functional optoelectronic imaging systems. By combining metasurfaces with image sensors, researchers break intrinsic absorption limits and enable true single-shot, multi-dimensional perception.
Researchers develop first quality-of-life measure specifically designed for Australian aged 65 and over, to improve care and outcomes. The tool will enable consistent monitoring of quality-of-life outcomes across health and aged care settings.
A stress-response gene, SmGA2ox4, has been identified in Salvia miltiorrhiza that enhances the plant's salt tolerance while boosting tanshinone production. Overexpression of this gene promotes antioxidant enzyme activity and ion homeostasis.
Researchers developed a prototype imaging system that can simultaneously track the cornea's mechanical response at nine locations, allowing for more accurate assessment of corneal biomechanics. This technology has the potential to improve early detection and monitoring of disorders like keratoconus.
Researchers have demonstrated large strain tunability of excitons in ZrSe3 under cryogenic conditions, showcasing exceptional strain sensitivity and potential for band structure engineering. This breakthrough highlights ZrSe3 as a promising material for next-generation Straintronics and flexible optoelectronic devices.
The University of Chicago Data Science Institute and Financial Mathematics Program launch a new industry-aligned certificate in quantitative development, combining training in advanced software engineering with financial expertise. Students will gain experience building real-world systems and preparing them to succeed in leading firms.
Researchers developed innovative mycelium-based composites using locally sourced fungal strains and lignocellulosic waste materials from Sri Lanka. The study introduces a sustainable approach to replacing synthetic protective packaging materials like expanded polystyrene, which are associated with significant environmental pollution.
A team from Xi'an Jiaotong University creates a novel flexible film with multiply indented, hybrid 3D-nanobowls, achieving ultra-high haze and excellent light transmittance. The roll-to-roll manufacturing process enables large-scale production at low cost.
Scientists identify key genes involved in lysine synthesis and virulence in Cryptococcus neoformans, a fungus that causes disease in humans. The study reveals the importance of de novo lysine synthesis for fungal virulence.
Fluctuations in nanopore structure are key to efficient molecule separation, according to a new study. The research found that dynamic 'breathing' motions can selectively accelerate the transport of one molecule over another, leading to improved separation performance.
A new study published by the American Society for Nutrition found that overall diet quality, not just food processing level, is strongly associated with long-term health outcomes. Healthy diets rich in whole grains, fruits, and vegetables are beneficial, even if they include some processed foods.
A new AI-driven EMG control framework has been developed to improve elderly assistance. The framework uses a 3-level approach to translate EMG signals into robotic assistive actions across various levels. It shows improved results in physiological signal labeling, functional multijoint intent decoding, and behavioral task adaptation.
Asteroid impact created a massive dust cloud that trapped heat, causing widespread wildfires and spontaneous combustion. The cloud led to population collapse and atmospheric contamination, ultimately killing most dinosaurs and other species.
A recent study found that recurrent heatwave exposure is linked to accelerated biological aging in middle-aged and older adults. The research, using data from the China Health and Retirement Longitudinal Study, discovered that increased heatwave frequency and duration lead to disruptions in lipid and glucose metabolism, ultimately acce...
Researchers developed a composite material with gradient electronic structure to efficiently absorb electromagnetic waves. The material exhibits exceptional performance, including high reflection loss and broad absorption bandwidth.
A recent study published in Biological Diversity reveals that ecological selection drives population differentiation and local adaptation in Capsella bursa-pastoris, a widely distributed annual herb. Genome-wide scans identified 54 candidate genes under positive selection related to energy metabolism and other processes.
A new study by McGill University researchers suggests that electoral competition can create challenges for social cohesion, especially as partisan animosity grows. Voters who strongly disliked rival parties show even greater distrust of their fellow citizens.
New study reveals how resistance exercise damages skeletal muscle and triggers a coordinated repair process. The research identifies key proteins involved in this network, providing insights into optimizing training programs for athletes and improving rehabilitation strategies.
A new study suggests that a global blanket of dust after the Chicxulub asteroid impact trapped and radiated enough heat to ignite worldwide wildfires, killing even the thickest-skinned animals. The intense heat pulse would have been 3.5 times more intense than without the dust blanket.
The NEMESIS experiment at the Sanford Underground Research Facility (SURF) seeks to improve knowledge on neutron background, a source of false signals in underground labs. By studying high neutron multiplicity events, scientists may uncover new insights into ultra-sensitive physics and potentially shed light on dark matter.
A new study published in the Journal of Inherited Metabolic Disease found that high-dose niacin therapy can improve survival outcomes in children with NAXD deficiency, a rare genetic disorder. The treatment has been shown to halt significant deterioration and reduce life-threatening complications.
Researchers have observed the strongest evidence yet for a companion star to Betelgeuse, which is about two to three times more massive than the Sun. The team used the European Southern Observatory's Very Large Telescope to obtain the clearest image of Betelgeuse B.
Researchers estimate that Mesolithic foragers occupied Malta between 8,500 and 7,500 years ago, surviving on the island due to long-distance sea crossings. The authors predict a population size of up to 419 individuals, which dropped to 170 by 9,000 years ago, suggesting a temporary or seasonal occupation.
Researchers discovered tunneling nanotubes that physically connect the membranes of cells in social amoebae, enabling the transfer of cytoplasmic components and organelles. These connections are found in multicellular organisms but were previously unknown in unicellular lineages.
A new study by Hanyang University ERICA researchers reveals how air exposure can trigger chemical changes in manganese-coated batteries, accelerating degradation. The team proposes a simple solution to suppress defective surface phases and restore stable manganese-oxygen bonding, leading to improved long-term durability.
Researchers developed an inverse-design framework to optimize magnonic crystal design, identifying unconventional lattice structures with large band gaps. The approach enables the exploration of previously unexplored material systems and device dimensions, paving the way for high-speed spin-wave computing and energy-efficient devices
The review explores how integrating Federated Learning (FL), Reinforcement Learning (RL), and Natural Language Processing (NLP) can overcome modern NLP system limitations, such as protecting user privacy and adapting to changing environments. The study presents a unified framework that combines FL, RL, and NLP as three co-equal pillars.
Researchers at Oregon State University developed a low-cost, semi-automated camera system using AI to monitor bumblebee populations and other insects. The system recorded six species of bumblebees, closely matching those documented through traditional methods, and identified them automatically using custom-built deep learning models.
A study by the University of Basel reveals how endothelial cells coordinate their cell-cell junctions to form continuous blood vessels. Pushing and pulling forces enable individual vessel segments to connect, allowing for the creation of a highly branched vascular network that supplies the body with oxygen and nutrients.
A study by the University of Edinburgh found that nearly 70% of participants experienced clinically significant sleep problems despite no known history of sleep disorders. The study also highlighted the importance of work-life balance and job satisfaction in determining overall wellbeing.
A landmark study identifies new genetic risk factors associated with fibromyalgia syndrome, pointing to a neurological origin of the disorder. The research found substantial overlap between fibromyalgia and other conditions, suggesting shared biological mechanisms that may benefit from targeted therapies.
Researchers at Nagoya University have developed a method to modify the inside of molecules, creating chiral nanocarbons with unique shapes and properties. These new materials exhibit spiral-shaped light emission, multiple electrical charges, and gas storage capabilities.
Infants use eye contact to select and synchronize their brainwaves with the speaker's, helping them learn language. They are not passive learners, but rather actively engage with social cues like eye contact and calling their name to determine what is important.
A landmark study published in Nature Medicine has identified 26 genetic variants that increase the risk of developing fibromyalgia syndrome. The study analyzed genetic data from over 2.5 million adults and found significant overlap with other conditions, such as low back pain and post-traumatic stress disorder.
Scientists at the University of Exeter have discovered two new mechanisms for how a well-established antibiotic works, which could lead to potential development of new antibiotic treatment. The study found that doxycycline targets the bacterial ribosome by blocking protein exit channels or reconfiguring it into an inactive state.
A new species of shrimpgoby, Tomiyamichthys oriens, has been discovered in Indonesian coastal waters. The fish boasts radiant orange markings and is named after its birthplace, Banyuwangi's 'Sunrise of Java' region.
The brain-inspired AI model employs human problem-solving strategies to solve complex problems, consuming significantly less energy than traditional large language models. The system utilizes cognitive maps to guide its approach, allowing it to adapt flexibly to changing situations without requiring retraining.
Researchers discovered that blocking autophagy in high endothelial venules reduces inflammation in mice with psoriasis, offering a promising new approach for treating chronic inflammatory and autoimmune diseases. This strategy targets the blood vessels rather than the immune system, preserving normal immune function.
Gaps in hepatitis prevention measures across Europe hinder efforts to eliminate the disease by 2030. Despite progress in vaccination and harm reduction, some countries struggle with low vaccine coverage and inadequate access to sterile needles for injecting drug users.
Researchers have identified a new indicator of obesity risk in children by studying circadian rhythm-related genes. The study, published in the journal Nutrients, found that certain gene variations may increase caloric intake or from specific macronutrients.
A new dimension of protection has been found in the interaction between ants and coffee berry borers. Small ant species can use the habitats created by the borers for their own reproduction, gaining a reproductive benefit. This discovery highlights the importance of observing nature and making basic scientific observations.
A KAIST research team found that algal blooms accelerate the early-stage weathering of plastics, leading to microplastic formation. The study suggests a new direction for managing water pollution and plastic waste together.
Researchers have developed a tiny circuit that can encode and decode digital information using a hidden property of electrons called valleys. The device generates, routes, and reads valley information entirely on chip at room temperature, demonstrating the potential for valley multiplexing to increase photonic chip capacity.
A €15 million EU-funded trial will investigate phage therapy as an alternative to antibiotics for recurrent urinary tract infections. Researchers from 13 countries, including Hebrew University and Hadassah Medical Center, will evaluate personalized bacteriophage therapy to treat antibiotic-resistant E. coli infections.
Researchers at Tohoku University discovered a paradox in REM sleep where the brain's energy molecule decreases despite an increase in fuel supply. This finding suggests that the brain dynamically adjusts its energy economy to support complex internal processing, revealing new insights into biological computation and sleep function.
Researchers found that lifelong PQQ and IPQ supplementation in senescence-accelerated mice reduced mortality risk during midlife and delayed aging progression. Middle-aged mouse supplementation also improved age-related muscular dysfunction. The study suggests a potential healthspan extension benefit of these compounds.
Researchers developed a self-adaptive Cu–Co catalyst that converts nitrate pollutants into green ammonia, achieving high activity and selectivity. The catalyst's adaptive reconstruction strategy enables it to continuously evolve into its most active state during operation.
A new clinical study demonstrates casdatifan's effectiveness in treating advanced kidney cancer with durable tumor responses and a manageable safety profile. The treatment targets HIF-2 biology and biomarker changes, supporting precision medicine approaches.
Researchers studied deformation-accommodating support systems incorporating yielding elements to address squeezing ground deformation in tunnels. The study found that the deformation behavior of the entire support system changes depending on the installation angle of yielding elements.
A new study published in eBioMedicine shows that combining irinotecan with standard chemoradiotherapy improves survival against advanced rectal cancer, particularly in those with high concentrations of cancerous cells. The AI-powered analysis revealed a 43% reduction in cancer recurrence and a 50% reduction in death risk.
Researchers found two widely used blood tests accurate in detecting Alzheimer’s pathology in participants with Down syndrome. The tests, Lumipulse G p-tau217 and PrecivityAD2, offer an easier path to diagnosis for this high-risk population.
This open-access publication presents journalism, poetry, fiction, and artwork produced by Indigenous writers and artists on climate change. The book introduces the relational worldview – an Indigenous way of thinking where everything impacts everything else.
Epithelial tissues respond to sustained mechanical stress by slowly reorganising their keratin cytoskeleton, forming supracellular networks that push the cell nucleus out of its protective cage. This process reveals a new mechanism for tissue adaptation and has implications for development and disease understanding.
PeroCycle announces global ambitions to decarbonise steel, cement, and chemicals industries with patented technology. Strategic partnerships with PKU Pioneer and io consulting enable rapid progress for PeroCycle.
Dr. Yi Li receives CPRIT funding to develop treatments for solitary fibrous tumor, a rare cancer driven by gene fusions. Researchers are working on novel therapies, including immunotherapy and antisense oligonucleotides, to reduce cancer-causing signal activity.
Researchers develop synthetic microbial communities to degrade persistent herbicides, improving degradation rates by 1.5-3 times compared to individual strains or natural attenuation. The approach promotes more complete mineralization of pollutants and resilience in complex soil environments.
A randomized controlled trial found that a comprehensive navigation service significantly improved self-reported access to needed resources among primary care patients. The study also highlighted the benefits of this model for Francophone minority populations, particularly in accessing French-language services.
Researchers at UCLA found a statistically significant relationship between cellphone ownership and lower reading scores in third and sixth graders. Children who owned cellphones had poorer comprehension regardless of whether they brought the phone to school or not.
A qualitative study identified four self-care decision-making patterns among adults with multiple cardiometabolic conditions, including past experiences and leveraging resources. Effective self-care behaviors can improve quality of life for these patients, particularly those with type 2 diabetes, coronary heart disease, and stroke.
Health system physicians value financial protections and clinical support teams, while independent physicians prioritize patient continuity and autonomy. The study's findings highlight substantial contrasts between daily practice experiences across the two organizational models.
Patients with long-term relationships to their family physicians may experience fewer urgent hospital admissions and lower hospital costs. This is due to consistently seeing the same general practitioner, which is associated with reduced hospital costs but not fewer urgent admissions.
A retrospective study found patients registered for longer periods had 9-21% lower odds of urgent hospital admission and 17-28% lower costs. Consistently seeing the same general practitioner was associated with 6-7% lower hospital costs but not fewer urgent admissions.
A new program taught family physicians to perform echocardiography using an AI-guided handheld ultrasound device, reducing wait times and costs. The approach, piloted in nine clinics across Spain, estimates annual savings of €70,000 per clinic.
A growing trend of patients turning to AI chatbots for health advice reflects broader healthcare system strain and patient dissatisfaction with traditional care options. Critical care doctor Robert B. Shpiner argues that addressing underlying structural issues is essential to mitigate AI risks.
A theory study identified 12 paradoxes in social care, including whether it promotes equity or stigma and tailoring care to context. The authors proposed three reconciliation strategies to address these tensions and integrate social care into primary care.
A qualitative theory study reveals three themes in how generalist physicians understand their work and role. The 'Way', 'Privilege', and 'Indescribable Whole' capture the essence of generalism as a time-centered, relational approach to patient care.
A three-year research award from Gabrielle’s Angel Foundation will support the study of transcutaneous auricular vagus nerve stimulation (taVNS) to manage chemotherapy-induced peripheral neuropathy symptoms. The goal is to improve quality of life for cancer patients with long-term effects of treatment.
A survey of 314 family medicine residency program directors found that only 44% have written expectations around self-directed learning. Despite this, 93.6% of directors believe recent graduates model lifelong learning, and over half (57.6%) consider self-directed learning a high curricular priority.
A new study reveals that forest structure, tree species evenness, and terrain slope jointly influence how carbon is divided among living vegetation, forest litter, and soil. The research found that soil contained the largest share of total carbon in most locations, while vegetation stored more carbon than soil in several plots.
Researchers found that plants absorb more elements with longer hydrated metal ion distances, suggesting a basic chemical influence on mobility. The metric may help estimate poorly studied contaminants and reduce reliance on complex variables.
A Canadian pilot study examined ways to link dementia patients' medical records with those of their caregivers. The report highlights critical gaps in clinical application due to EMR incompatibility, varying provincial privacy rules, and consent requirements.
The chosen fellows will undertake residencies in eight European countries, tackling topics such as earthquakes, fusion energy, quantum mechanics, and biodiversity loss. The cohort brings together nine nationalities and includes early-career, mid-career, and established professionals.
A middle school substance-use prevention program led to wide-ranging benefits well into adulthood, including better communication with romantic partners and better-adjusted children. Parents who participated in the program reported lower levels of family conflict and higher levels of family cohesion.
Researchers at Kennedy Krieger Institute discovered that memory consolidation during sleep depends on coordinated activity among three brain regions, disrupting this activity impairs memory performance. Epileptic spikes can also interfere with brain activity, leading to cognitive effects in patients with epilepsy.
A randomized controlled trial in Singapore found that offering self-sampling increased both high-risk HPV detection and overall screening uptake among previously unscreened women. Screening uptake also increased particularly among women with no prior screening history. In contrast, patients registered with their general practice for lo...
Studies show that plant fibers and proteins, known as 'proteins imitating fiber,' reprogram microbial metabolism to produce beneficial phenol metabolites. These findings highlight the potential of diet in controlling the microbiome and its outputs.
A new type of 3D-printable material mimics human tissue's ability to sort and filter, allowing certain molecules to pass through while keeping others out. This broad function means the material can be used in various applications across medicine, water, and robotics.
A new study from Costa Rica's Área de Conservación Guanacaste found that high-elevation species of rove beetles are poorly equipped for warmer temperatures, while low-elevation insects live close to their heat limits. This suggests that tropical biodiversity may be vulnerable to rapid climate change.
Researchers identified a rare genetic mutation, BTK A428D, that blocks both BTK inhibitors and next-generation BTK degraders. The study provides new insight into how cancers evolve under treatment pressure and may help develop strategies to overcome resistance in patients with chronic lymphocytic leukemia.
A new grant will support research into how strokes disrupt brain networks controlling the bladder, aiming to identify imaging biomarkers predicting treatment response. Researchers will use advanced brain imaging and non-invasive spinal stimulation to develop a personalized approach for treating bladder problems after stroke.
The program combines technical innovation and strategic business thinking, offering four specialized tracks: business analytics, finance, marketing, and IT management. Students will earn both a Bachelor of Science in engineering and a Master of Science in business.
Researchers discovered a lipid regulator, arachidonic acid, boosts Smoothened activity through a newly found binding site, enhancing SHH signaling in tissues like the heart and lungs. Disrupting this interaction impaired cardiopulmonary development, providing insight into how the SHH pathway may be modulated in diseases.
A large-scale genetic study suggests that inherited taste preferences for sweet and fatty foods can influence eating behaviors and contribute to chronic disease risk. People with a higher genetic predisposition for these tastes tend to eat more of them, leading to a higher risk of obesity and type 2 diabetes.
A new study reveals that industrial poultry farming has led to a 100-fold increase in Campylobacter movement, allowing strains to mix extensively in commercial poultry populations. This has resulted in more than 3.5 times as many gastroenteritis cases in the UK each year compared to other foodborne bacteria.
A study of ancient human relatives' fossil footprints reveals that a previously thought smaller species was actually larger, while also showing evidence of group travel. The tracks, preserved over 1.4 million years ago in northern Kenya, offer insights into the behavior and interactions of these early humans.
A new study documents fossil footprints of eight adult Paranthropus boisei individuals, indicating human-like body sizes and complex social structures. The discovery provides a rare snapshot of 'fossil behavior' from an ancient hominin group in northern Kenya.
A new AI model called Biogeochemistry-Informed Neural Network (BINN) has been developed to advance scientific discovery in agriculture and biogeochemistry. It is 50 times more efficient than its predecessors and can predict biological processes not yet well understood.
Researchers found that genetic factors play a role in how individuals respond to a low-carb, high-fat diet, with those at higher risk experiencing greater increases in LDL cholesterol. The study suggests personalized dietary guidance based on genetic profiles could help identify who may experience adverse responses to certain diets.
The VERITAS project establishes AI Assurance as a core function of scientific research infrastructure to document, review, and stress-test AI systems. It aims to develop practical methods for detecting vulnerabilities before they compromise scientific results.
Baskin is the first female and first Black woman to be named director of a National Cancer Institute-designated cancer center, leading Massey Comprehensive Cancer Center. She champions the community-to-bench model, prioritizing rural areas and underserved groups in cancer prevention and treatment research.
A soft, wearable fingertip patch continuously monitors levodopa levels in patients' sweat, comparable to standard laboratory blood tests. This technology enables precise customization of daily medication schedules for patients at home, potentially improving treatment outcomes.
USC researchers have been selected for the U.S. Department of Energy's Genesis Mission to harness artificial intelligence for scientific discovery and innovation. Two projects led by USC will explore ways to develop faster and more energy-efficient computing hardware and better understand the natural concentration of critical minerals.
Researchers developed an antibiotic-free multifunctional injectable hydrogel that promotes tissue repair through synergistic antioxidant and antibacterial activity. The hydrogel shows compatibility with blood and surrounding tissues, delivering therapeutic agents in a controlled and sustained manner.
A new study reveals that lignin can be transformed into a bioactive material that promotes the formation of bone-like minerals while supporting the growth of bone-forming cells. The material also degrades gradually under physiological conditions, making it suitable for scaffolds intended to be replaced by newly formed bone during healing.
A study by USC researchers found that signals from the gut through the vagus nerve can help form memories, particularly those related to food. The brain responds to a food's nutrients rather than just its flavor, suggesting a potential mechanism for memory formation.
Researchers have developed an AI tool that can detect online propaganda in Kinyarwanda, a Bantu language spoken by 350 million Africans. The dataset, called KinyaProp, provides examples of misinformation in Kinyarwanda for large language models to learn from and recognize.
Researchers have created a new, recyclable yarn that mimics the properties of spandex-based yarns, offering an alternative to non-recyclable stretchy garments. The yarn is made from a form of plastic and can be melted down and reused multiple times without losing its strength and flexibility.
The Genesis Mission aims to accelerate breakthroughs in energy, scientific discovery and national security through AI-powered research. Texas A&M University has joined the initiative, contributing to a unified discovery platform connecting government, industry, academia and philanthropy.
Researchers detected chlorinated organophosphorus esters in solid waste, linked to toxic effects on the endocrine and reproductive systems. The substances, used as flame retardants, can cause cancer and harm human health if not managed properly.
Researchers at UC Irvine analyzed 100,000 inspection records to identify key factors responsible for severe wildfires in California. The team developed a high-resolution fire risk map that highlights areas with the highest probability of property losses.
A study by North Carolina State University researchers found that an AVP stimulation test can reliably diagnose endocrine dysfunction in sick foals. The test, which involves administering arginine vasopressin to stimulate the release of hormones, showed promising results in detecting hypothalamic-pituitary-adrenal gland axis (HPAA) dys...
A randomized trial found a significant reduction in alcohol use among refugees and locals in Mantapala refugee settlement. The SBIRT intervention was more effective than treatment as usual, with sustained effects over 12 months.
Researchers have created a new approach to cancer vaccine design by leveraging pre-existing antiviral immune memories. PROTEXI, a dendritic cell vaccine platform, converts dormant antiviral memory into a catalyst for antitumor immunity, slowing tumor growth and improving survival in multiple preclinical models.
Researchers identified key genes controlling cellulose, hemicellulose, and lignin synthesis in Ginkgo biloba wood. The study's findings offer a roadmap for breeding superior timber varieties with tailored properties.
A UTEP researcher has developed a simple, low-dose leaf spray that can substantially reverse the damage caused by salty soil on tomato plants. The treatment pairs manganese oxide nanoparticles with chitosan and has been shown to increase shoot weight, root growth, and antioxidant enzyme activity in stressed plants.
A recent international workshop led by UC Santa Barbara researchers has taken the first steps toward developing a large-scale strategy for carbon sequestration by burying plant biomass in anoxic marine basins. The concept, known as marine anoxic carbon storage (MACS), has the potential to operate at a massive scale required to mitigate...
Researchers discovered that dengue virus can infect memory B cells, immune cells traditionally understood to help protect the body from infection. This finding points towards new strategies for treating dengue, a disease threatening 40% of the world's population.
A new $3.3 million study aims to investigate how people perceive cognitive changes as they age, with a focus on identifying predictive markers for dementia. The 'worried well' - individuals with cognitive complaints but normal test results - may hold clues to early disease detection.
The University of Tennessee has appointed Carolyn J. Anderson as a UT-Oak Ridge National Laboratory Governor's Chair for Nuclear Medicine. She will focus on researching radioisotopes produced at ORNL for targeted alpha-emitting radiotherapy, which can precisely kill cancer cells with minimal side effects.
A SKKU study finds that concentrated aid support from a single agency reduces local corruption, but overlapping aid agencies increase the risk of corruption. The research team analyzed data from over 30,000 projects across Afghanistan and found that moderate aid volumes with collaborative project ideas have a positive impact.
Research explores whether eyes being open or closed affects brain activity related to mind wandering and arousal. Brain activity associated with arousal has opposite effects on mind wandering depending on eye state, suggesting a context-dependent relationship.
Astronomers spot supermassive black hole on outskirts of galaxy, defying assumption that it resides in the center. The discovery uses AI program to identify characteristic light patterns from tidal disruption events.
Researchers found that long-term systemic treatment with senolytic PROTAC 753b slowed several features of age-related intervertebral disc degeneration in male mice, preserving extracellular matrix protein aggrecan and reducing inflammatory markers. However, female mice showed little improvement, suggesting a sex-specific response.
A microscopic atlas reveals how citrus Huanglongbing disease develops over time, causing phloem cell death and callose deposition in leaves and fruit tissues. Roots experience starch depletion, driving root decay and nutrient deficiencies.
The first patient has been enrolled in a global Phase 3 clinical trial evaluating Mocertatug Rezetecan, a novel B7-H4-targeted ADC, in platinum-resistant ovarian cancer. The study aims to determine whether this therapy can improve outcomes compared with standard chemotherapy.
Experts warn that US suicide deaths are undercounted due to misclassification of drug overdoses as accidental deaths. A new measure, self-injury mortality, aims to shift the focus from intent after death to accounting for behaviors prior to death.
Researchers at University of Missouri develop natural colorants from purple corn, showing stability and durability in various environments. The anthocyanins, rich in antioxidants, offer a viable path for food companies to create cleaner labels without sacrificing performance.
A new analysis of 19 randomized controlled trials found that different GLP-1 medications have distinct effects on heart and metabolic health, suggesting a need for personalized treatment selection. Oral GLP-1 therapies are emerging as strong options that could expand accessibility and flexibility.
Researchers developed a soft, stretchable antenna that can maintain stable wireless connections even during movement. The antenna's design allows it to compensate for changes in shape and size, enabling wearable devices to track vital signs continuously and reliably.
A new method integrates remote sensing and meteorological data to estimate leaf age of winter wheat before overwintering. The study found that the method significantly improved accuracy compared to traditional methods.
A new study reverses the classic Dunning-Kruger effect, suggesting that high-ability people are more overconfident than low performers. The researchers argue that flawed statistical analysis led to the original finding, and when corrected, it reveals a universal human trait of overconfidence among the most capable.
Researchers have developed a novel double-shell host material that overcomes the notorious shuttle effect in lithium-sulfur batteries. The material's dynamic electrochemical microenvironment actively transports polysulfides away from the catalyst surface, preventing passivation and ensuring sustained high catalytic efficiency.
A study of human remains from an Italian necropolis provides clues about the daily lives of people 2,700 years ago. The analysis of isotopes in bones, teeth, hair, and nails reveals differences in diet between men and women, as well as a society with significant mobility and contact with other populations.
A transient electronic state plays a key role in the formation of a photoinduced hidden state in a metal–organic framework, which can be controlled with light for future applications. The study provides new insights into designing materials with novel optical properties.
A new study from UT Health San Antonio found that Hispanic populations experience higher rates of frontotemporal dementia, with significant delays in diagnosis due to educational disparities. The research highlights the importance of culturally sensitive diagnostic tools and interventions for equitable dementia care.
Research reveals CUDC-907's therapeutic potential in combating glioblastoma by inhibiting PI3K and HDAC, leading to enhanced TMZ sensitivity through disrupted double-strand break repair pathways.
Meablex's innovative prosthetic arm addresses challenges of traditional devices, including adjustable sockets and reliable control systems. The company's technology combines lightweight soft robotic materials and advanced 3D-printing to improve the quality of life for people with upper limb loss.
Researchers uncover CXCR4's role in suppressing aldosterone production by upregulating ID3, a transcription regulator that halts CYP11B2 expression. This novel signaling axis offers a new strategy to combat autonomous hormonal overproduction and severe secondary hypertension.
A new study of an Israeli hospital's response to the October 7 attacks reveals critical gaps in communication, staffing, logistics, and casualty distribution. The findings offer practical lessons that could help hospitals worldwide prepare for prolonged armed conflicts and other large-scale emergencies.
Researchers found that populations of small invertebrates thrive near rat-infested islands, where seabirds are scarce. In contrast, fish biomass is higher on reefs without rats, benefiting from nutrient-rich guano deposits.
A new grant will allow researchers to develop a non-invasive magnetic resonance imaging (MRI) exam to detect early changes in tissue and improve diagnosis and treatment for lymphedema and lipedema. The SALT MRI approach tracks sodium, adipose tissue, and lymphatic fluids to better understand how they affect lymphatic function.
A research team studied ion-exchange membranes to understand their structure and ability, finding that flexible backbones achieve higher ion conductivity with less water uptake. This discovery offers molecular-level design guidelines for next-generation energy devices.
A new liquid-based platform called 'floatony' can form and maintain complex three-dimensional microbial structures while preserving molecular diffusion, spatial structures, and cell mobility. This approach could offer new ways to study gut microbiota, biofilms, and other spatially organized microbial communities.
The Cluster of Excellence 'The Politics of Inequality' investigates how inequality can be reduced through specific political conditions. Research projects focus on rectification for historical injustices, biological ageing processes, and household decisions to prevent perpetuation of inequality.
Scientists at Houston Methodist Research Institute have created a biodegradable implant that delivers cancer-fighting drugs directly to tumors, slowing their release over time. The device showed promising results in preclinical models of triple-negative breast cancer, eliminating tumors in 60% of cases without significant side effects.
A study of over 350,000 students found teachers predict higher A-Level grades for girls than boys with similar results. The 'halo effect' may contribute to this gap, where positive impressions about girls spill over into predictions.
Researchers used machine learning to identify seven rare quasar candidates from a list of 800,000 quasars. The discovery offers an opportunity to expand knowledge of how quasars and their host galaxies work, as well as understanding our own galaxy's evolution.
Researchers have calculated fundamental laws of thermodynamics for a gas made up of spinning particles, finding that pressure is similar to a normal gas but at an elevated temperature. Localized surface currents also arise, enabling targeted particle transport.
A new survey found that Native American adults are open to healthier eating based on traditional Indigenous foods, with 78% willing to try a whole food, plant-based diet. However, only 13% are aware that such diets can help prevent or improve type 2 diabetes.
Researchers found type III interferons reduce disease severity in autoimmune uveitis by suppressing Th1/Th17 responses and NLRP1/NLRP3 inflammasome activation. This study identifies IFN-λ as a promising immunomodulatory agent for autoimmune uveitis.
A comprehensive review of dementia prevalence and risk factors in India reveals unique health outcomes for South Asian populations. The study sets the stage for the SAMARTH initiative, tracking brain health in South Asian Americans to identify modifiable risks and protective factors.
A new concept from Warwick researchers introduces Quantum Phononic Links, which use sound vibrations to carry quantum information between qubits across an entire semiconductor chip. This approach enables long-range qubit connectivity, paving the way for building large-scale quantum computers with millions of qubits.
The American College of Lifestyle Medicine (ACLM) has earned Joint Accreditation for Interprofessional Continuing Education, allowing it to independently accredit its own interprofessional continuing education activities. This enables ACLM to deliver high-quality, team-based training that strengthens collaboration and improves patient ...
A new statistical model predicts which Red Sea fish species are likely to invade the Mediterranean, with a focus on their ability to survive without coral reefs. The study identifies three species with high potential to invade: stellate pufferfish, cinnabar goatfish, and yellowspotted trevally.
Hepatopulmonary syndrome is characterized by pulmonary angiogenesis and refractory hypoxemia, with agrimoniin treatment attenuating pathological changes by restoring mitochondrial respiration and reducing glycolytic activity. Activation of PGC-1α is essential for mediating improvements in vascular remodeling and metabolic balance.
Researchers compared common blood-based biomarkers for predicting eventual Alzheimer's dementia and found that P-tau 217 had moderate predictive power in the preclinical stage. In contrast, a biomarker for amyloid beta protein misfolding was highly predictive even in cognitively normal individuals.
New research finds that exclusive cigarette use is being replaced by exclusive use of electronic cigarettes, especially among young adults. The study's findings have important implications for predicting the future burden of tobacco-related cancer and highlight a need to address smoking cessation among older adults.
Astronomers at UNC-Chapel Hill have observed an extremely rare 'wandering' black hole located tens of thousands of light-years from the center of its galaxy. This discovery could reshape our understanding of how massive black holes move through the universe after galaxies collide.
Researchers developed a novel blended-PPY conductive polymer with graphene oxide and indium tin oxide nanoparticles for enhanced antibacterial performance. The resulting nanocomposites showed improved optical behavior and broad-spectrum antibacterial capacity.
Dr. Enrico Novelli leads a newly launched network to expand access to care for patients with sickle cell disease across Maryland. He brings expertise in SCD and blood vessel biology, as well as global efforts to strengthen hematology care.
Researchers have identified a new powdery mildew resistance gene, Pm72, from wild einkorn wheat that will be useful for wheat breeding. The gene was found to confer effective resistance to all ten pathogen isolates tested and can be detected using a diagnostic marker.