Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A team from Tokyo Metropolitan University developed a system to test magnetohydrodynamic aerobraking for spacecraft reentry. They successfully generated strong magnetic fields using an electromagnet, exceeding previous results with permanent magnets.
A team of researchers led by Texas A&M University has discovered Atlantic herring possess exceptionally high diversity in their MHC class II genes, a group of immune genes involved in recognizing pathogens. This diversity is shaped by natural selection driven by the evolutionary
Researchers have developed an ultracompact gene activation tool called TIGRa, which can target multiple genes simultaneously and is smaller than CRISPR-based tools. TIGRa was tested in a mouse model and showed promising results in treating retinal degenerative conditions, including glaucoma.
Researchers at Yale University have discovered two ancient, extinct giant tortoise lineages using a new combination of computational tools. The findings can aid conservation efforts in the Galapagos archipelago by unlocking the genetic diversity of extinct species.
Researchers developed new guidelines to study molecular biomarkers associated with stroke recovery. The recommendations aim to identify biological signals that can help clinicians determine the most effective therapies for each patient at the right moment. The guidelines also emphasize the importance of creating national biomarker cent...
Researchers discovered how tumors interact with the body to grow and spread, revealing a new target for cancer therapy. Metadherin, a protein encoded by the MTDH gene, mediates this metabolic-immune crosstalk, supporting tumor growth and metastasis.
Researchers at Texas A&M University are working on a project to develop a mobile and efficient drilling system that combines faster drilling technology, real-time rock analysis, and artificial intelligence to identify valuable minerals in real time. This project aims to reduce the time needed to evaluate potential deposits of rare eart...
The researcher will investigate how infected cells live and die, and what chemical signals they release to surrounding cells. This work could lead to better antiviral drugs and virus-based cancer treatments.
A new Concordia study suggests that reducing fast fashion's environmental impact can be achieved through changes in manufacturing, transportation, and consumer use. By producing fewer garments, designing them with longevity in mind, and cutting back on air freight, the fashion industry can achieve significant environmental benefits.
Researchers developed SOT-MRAM, a fast and energy-efficient memory tech, to address AI's increasing energy needs. The technology can reduce energy consumption by up to 5x, making it suitable for edge devices and applications where power is limited.
A new study identifies a distinct population of lung vein cells that contribute to scar tissue formation, a process known as fibrosis, in diseases like pulmonary fibrosis. The researchers found that targeting a specific signaling pathway can prevent lung scarring and inflammation.
A new study found that nearly 20% of eligible adults in Medicaid expansion states are at risk of losing health coverage due to insufficient or inconsistent work hours. Women, unmarried people, and those with limited education are disproportionately affected.
Two new research chairs at UVic will focus on improving climate-ready ocean stewardship and prevention-focused health research. Elliott Hazen will lead efforts to identify early ecosystem warning signals and collaborate with Indigenous communities to support climate-responsive ocean stewardship. David Almeida will establish a digital a...
A new study from the University of Georgia found that Joro spiders eat different insects and a wider variety than native orb weavers, suggesting they don't compete for food. However, Joros are still taking up physical space, but can often be found alongside native spiders in their webs.
Cyclin D1, a protein linked to cancer, paradoxically promotes chronic inflammation in non-proliferating senescent cells, which can lead to age-related disease. Research suggests that targeting cyclin D1 may be a promising strategy to reduce inflammation and promote healthier aging.
A new theranostic pair, 68Ga/177Lu-NYM096, shows excellent tumor uptake in clear cell renal cell carcinoma lesions and demonstrates early evidence of tumor response in patients. The radiotracer can identify tumors and deliver targeted radiotherapy, mitigating toxicity issues common with treatment.
A warming tropical pool has temporarily slowed Antarctic ice loss by triggering a Rossby wave train and reorganizing moisture transport, resulting in a 695 billion-ton mass gain. This phenomenon, linked to tropical warm-pool warming, demonstrates the complex interactions between atmospheric circulation and ice sheet mass changes.
The American Academy of Neurology launches BrainHealth.com, a public resource providing expert-reviewed information, tools, and stories for brain health. The website offers evidence-based guidance and practical resources for individuals to make informed choices for their brain health at every stage of life.
Thomson Reuters developed a frontier AI model named Thomson that rivals big foundation models with a $40 million development cost. The approach allows organisations to build and deploy frontier AI systems without major frontier labs' resources, addressing governments' and companies' need for sovereign AI systems.
Researchers found that impaired peroxisomal function can increase insulin secretion while promoting insulin oxidation and disrupting pancreatic beta cell maturity. Healthy peroxisomes play a role in protecting insulin from oxidative modification and degradation, and helping beta cells maintain their specialized characteristics.
Researchers are studying the male role in early pregnancy loss, focusing on paternal epigenetics and its impact on fertility and pregnancy. By analyzing sperm from bulls with high and low fertility, the team aims to understand how nongenetic changes to DNA affect embryo development and gene regulation.
Researchers have created a high-resolution functional map of human immune cells, revealing intricate circuits that govern health and disease. The dataset provides a powerful framework for designing cancer immunotherapies and treating autoimmune conditions, and serves as a foundation for AI models of biology.
Researchers developed fluorescent molecules that allow imaging of DNA inside living cells at unprecedented resolution, and in preserved cells, close to the width of the double helix. The team tested the probes on cancer patients and found DNA to be noticeably looser and more spread out in tumours.
Researchers have mapped how the immune response in people with sepsis changes over time, revealing three distinct immune states. This finding could lead to targeted treatments for sepsis patients, as the immune state doesn't match the clinical stage of sepsis.
Digital tools are transforming clinical research, public health readiness, healthcare institutions, and consumer choices. Citizen science initiatives using mobile apps are also growing, with three types of citizen science identified: with-the-people, by-the-people, and for-the-people.
Researchers have identified a subset of B cells known as atypical memory cells as the primary precursors of autoantibody-producing cells during SARS-CoV-2 infection. These cells adopt a markedly different biological program, leading to increased autoantibody production. The study provides new insight into how viral infections can trigg...
A study found that higher breastfeeding intensity is associated with more favorable early postpartum lipid profiles among women with prior gestational diabetes. Greater breastfeeding intensity may be linked to a more favorable early cardiometabolic profile in these women.
A team led by Professor Paulin Straughan is studying how urban design and infrastructure influence physical activity, mobility, and social participation among older adults. The goal is to create a sustainable approach to wellbeing-management through
A new generation of intelligent decision support methods and software tools will be developed to enhance supply chain resilience, optimize healthcare operations, and strengthen emergency response coordination. The HOPE project aims to create a lasting area of excellence in human-centered AI, serving as a trusted partner for government,...
A recent study aims to evaluate the effectiveness of Healthier SG in cancer screening, focusing on improving systems and boosting habits. The research seeks to address knowledge gaps in evidence-based planning for Singapore's preventive care agenda.
Researchers found that reef fish exposed to motorboat noise as embryos and juveniles grow smaller and have impaired survival skills. The study suggests that limiting motorboat traffic near reefs during breeding season may help preserve coral reefs.
Researchers developed a Mo alloy with high strength, good ductility, and excellent thermal stability at high temperatures, overcoming conventional dispersion-strengthened Mo alloys' limitations. The alloy retained stable mechanical properties after long-term annealing at 1000 °C.
Kajetan Fijalkowski developed a method for determining electrical resistance without an external magnetic field, opening up new possibilities for future measurement systems. This achievement contributes to the foundations of metrology and has implications for linking different electrical units.
A new study from the University of Copenhagen and Nordsjællands Hospital found a 75% reduction in hospital admissions among infants aged 0-5 months in Denmark following the rollout of an RSV vaccine for pregnant women. This significant decline suggests that the vaccine is effective in reducing the burden of severe RSV disease.
Researchers from the Max Planck Institute for Solar System Research have determined Mercury's surface silicon dioxide content with greater accuracy, finding it up to 25% less abundant than previously thought. This suggests the volcanic rocks on Mercury formed from more deeply melted mantle material than previously assumed.
Researchers at Ludwig-Maximilians-Universität München identify a molecular mechanism enabling single-celled parasites to move and invade host cells through lysine methylation. This regulatory layer connects signaling, cytoskeletal activation, and mechanical force, offering a promising starting point for drug development.
Researchers developed a plyometric-based high-intensity interval training (Plyo-HIIT) program to preserve muscle while reducing fat in children aged 9-12. The 16-week program showed promise in improving muscle-to-fat ratio, prioritizing metabolic health over weight reduction.
Researchers have developed a programmable directional photonic spiking neuron based on a non-Hermitian silicon microresonator. The device, called DRUM, can emit spikes in one direction while remaining inactive in the other, reducing unwanted crosstalk and enabling true directional interaction.
The Plant Journal has transitioned to gold open access, removing paywalls and making its research freely available. This change is part of the Society for Experimental Biology's strategy to support the plant science community and ensure discoveries reach the widest audience.
Researchers developed a new approach to multi-camera identity tracking by combining camera geometry and visual appearance. The method achieved high IDF1 scores on benchmarks, demonstrating improved tracking continuity across different environments, but highlighted limitations in detecting people in severe occlusion.
A new study suggests that children with cerebral palsy born very preterm may need closer nutritional and rehabilitation monitoring due to higher risks of undernutrition and functional impairments. The study found that gestational age should be considered when assessing nutrition and rehabilitation needs in children with cerebral palsy.
Researchers identified a critical postnatal window in which excessive FGFR2 signaling drives coronal craniosynostosis by reducing GLI1+ progenitors and promoting abnormal osteogenesis. Restoring suture patency or RA signaling rescues structural and neurocognitive abnormalities.
The robots use torsion to store elastic energy and release it all at once, causing them to jump and repeat the process as long as they are exposed to infrared light. Design changes can control the movement, such as jumping forward or leaping vertically.
Researchers have developed a heat-driven, elastocaloric cooling system that leverages waste heat and solar energy for sustainable cooling. The system achieves a temperature difference of 4°C on the component level, demonstrating its feasibility.
Researchers at the Max Planck Institute for Polymer Research have identified the electrical charge of droplets as a new factor contributing to surface corrosion. Charged droplets can puncture coatings like Teflon, causing damage and reducing durability.
A new trial has found that implanting an ICD in patients with mild-to-moderate heart dysfunction can reduce sudden cardiac death, particularly in younger patients. This breakthrough has the potential to save lives and expand treatment options for patients who previously were not eligible for ICDs.
Researchers have demonstrated that nano-antennas can enhance the fluorescence of proteins in living human and other mammalian cells, allowing for faster and more precise monitoring of electrical signals in the brain. This discovery adds a new tool for revealing electrical signals in the brain, using nanotechnology and genetic engineering.
Researchers at the Max Delbrück Center have developed a search engine, Malva, to analyze single-cell RNA data, enabling rapid analysis of millions of cells worldwide. Malva simplifies the task of wading through data from thousands of experiments and provides insights into RNA biology, cancer, and disease mechanisms.
Researchers developed a dual-threshold approach for measuring tumor volume on PET/CT, showing higher total lesion volume associated with shorter overall survival and time to treatment failure. FAPI PET/CT improved detection of ovarian cancer spread, while CD8-targeted PET tracked immune response in lung cancer.
Researchers at Tsinghua University Press review Pt-based catalysts for the reverse water-gas shift reaction, highlighting the importance of structurally defined active centers and defect-anchored single atoms. The study identifies priorities for future research, including improved stabilization of single-atom and sub-nanometer Pt species.
Researchers developed high-performance flexible thermoelectric generators with planar and multilayer-stacked structures, overcoming material flexibility and mechanical stability challenges. The devices achieved high energy conversion capabilities and demonstrated practical potential for wearable thermoelectric energy harvesting.
A new coating developed by Professor Zhang Yuxin's team achieves long-term adaptive anti-corrosion for magnesium alloys, overcoming the limitations of traditional epoxy resins. The coating combines a hierarchical composite system to provide both long-term barrier protection and on-demand release of corrosion inhibitors.
A collaborative research team has successfully upcycled phosphine waste into high-value electrocatalysts for hydrogen evolution, a critical process for a hydrogen economy. The catalyst achieves exceptional performance in water splitting, making hydrogen production spontaneous and thermodynamically favorable.
Researchers have developed a concentration-gradient strategy to stabilize cell voltage for high-yield formate production via CO2 electroreduction. The strategy uses a concentration gradient to offset the voltage increase caused by cation migration, resulting in stable operation for up to 30 hours. This breakthrough enables efficient gr...
A new study found that off-equatorial Pacific warming halted La Niña development by inducing equatorial westerly wind anomalies, breaking the Bjerknes feedback. Climate models have been improved by refining ensemble forecasting frameworks to fully integrate off-equatorial ocean signals.
The updated expert consensus offers a practical roadmap for recognizing and treating childhood nocturnal enuresis, emphasizing symptom-based classification, individualized first-line treatment, and management of daytime urinary symptoms. The framework aims to provide more standardized, individualized, and family-centered care.
Dr. Sebastian Spethmann joins JMIR Cardio as Editor-in-Chief, bringing expertise in heart failure, cardiomyopathies, and digital health. He aims to integrate digital advancements into routine clinical care, enhancing cardiovascular health systems and patient outcomes.
Researchers from SWPS University found that mimicry in social interactions doubles tobacco consumption and makes quitting difficult. The study showed that when participants mimicked the smoker's movements, they were more likely to smoke and less likely to quit.
Insilico Medicine leaders will share AI-driven insights at key tech events, including LEAP 2026 and the UBS China A-Share Conference. The company will discuss how AI drug discovery is reshaping R&D paradigms, enhancing efficiency and innovation value.
Researchers at KIER develop technology to separate current collectors from spent battery cathode materials, regenerating materials to near-pristine condition. The process uses diethylene glycol solution, enabling complete separation and simultaneous regeneration of cathode materials.
A new study highlights the impact of coastal freshening on the giant amphipod species Paraceradocus miersi, which lose salts, gain water, and suffer gill damage in diluted waters. The research warns that continued freshening may pose a significant threat to many marine invertebrates and reshape the global ocean's communities.
Researchers identified a compound, PF-04457845, that slows ALS progression in mice, with potential as a therapeutic option. The compound targets N-acyl taurines, which correlate with ALS progression, and has been proven safe in humans.
Research suggests that insects struggle with hypoxia and hypobaria at higher elevations, limiting their ability to pollinate and survive. Insects with aquatic larval stages and high energy demands are particularly affected, highlighting the need for targeted conservation strategies.
A Swedish study found that short-term exposure to cold spells and higher ambient temperatures increased the risk of heart failure hospitalization within days. The study highlights the need for time-sensitive management and more urgent response strategies during heatwaves.
The new ESC Guidelines on cardiac rehabilitation emphasize its benefits for patients with various heart conditions, improving heart health and reducing the risk of cardiac events. The guidelines also highlight the importance of individualized programs, patient-centered care, and cost-effectiveness.
The 2026 ESC Guidelines on heart failure introduce significant changes, including a staging approach and removal of the mildly reduced ejection fraction phenotype. New recommendations focus on prevention, early treatment, and patient education, with updated therapies for specific patient populations.
A universal definition of myocardial infarction has been developed to improve diagnosis and treatment. The new definition considers the underlying cause of the MI and aligns with established approaches to clinical evaluation.
Researchers at EPFL's POWERlab have developed a new class of GaN transistor that can withstand nearly 4 kilovolts before breaking down, maintaining low resistance and reducing energy losses. This innovation is crucial for efficient power conversion in AI data centers and renewable energy systems.
A research team at the Wyss Institute has engineered bacteria to produce higher amounts of siderophores, molecules that extract iron from silicate minerals, speeding up rock weathering and removing CO2 from the atmosphere. This process has the potential to be implemented at industrial scales, offering a new climate-regulating strategy.
The new guidelines aim to increase kidney function and urine albumin testing in patients with CVD, identifying at-risk patients and prescribing targeted treatments. Early use of RAS inhibitors and SGLT2 inhibitors, alongside statin-based therapy, is particularly important in slowing CKD progression and reducing cardiovascular events.
Optical convolution computation enables parallel light propagation and multiplexing for faster and more energy-efficient computing systems. The review organizes the field into two paradigms: definition-based and theorem-based, which leverage mathematical principles to implement convolution operations in the physical domain.
A randomized trial found that patients with atrial fibrillation at intermediate risk of stroke experienced a 69% lower risk of adverse events with oral anticoagulants compared to no treatment. The study also showed a lower incidence of ischemic stroke with anticoagulant therapy.
The CARDIO-TTRansform trial investigated eplontersen in patients with transthyretin-mediated amyloid cardiomyopathy, but failed to meet its primary endpoint. The study found that eplontersen reduced circulating serum TTR, but had no significant impact on cardiovascular mortality and recurrent cardiovascular events in the overall popula...
A tailored strategy shortened antibiotic duration by two weeks in patients with left-sided infective endocarditis, with no compromise on safety. The study found that rates of primary relapse were low, and most were easily managed with reinitiation of antibiotics.
Researchers propose a new understanding of moral distress that links ethical awareness with clinician well-being, organizational culture, and patient care. The framework offers a clearer foundation for future research, suggesting that moral distress may sometimes be a sign of strong ethical awareness rather than personal weakness.
The ACACIA-HCM trial showed aficamten significantly improves symptom burden and exercise capacity in patients with symptomatic non-obstructive hypertrophic cardiomyopathy. Clinically meaningful improvements were documented for the first time in this relatively common form of inherited heart disease.
ICDs did not improve overall primary endpoint but showed benefit in younger patients (under 70) with a 72% reduction in sudden cardiac death. In contrast, older patients did not derive benefit from ICDs.
A University of Helsinki research group has discovered a weakness in aggressive breast cancer cells that can be exploited, targeting the MYC protein's metabolic grip. By inhibiting energy production and glutamine uptake, researchers were able to slow breast cancer growth in mice, paving the way for new and personalised treatments.
Researchers developed a machine learning-based time-to-event model that outperformed existing staging systems in predicting mortality and heart failure hospitalization in transthyretin amyloid cardiomyopathy patients. The model showed promise for individualized prognosis in contemporary clinical care.
Researchers developed a hierarchical graphene nanowall nanomesh that enhances sensing performance and enables long-term gas monitoring on wearable masks. The 'nano-on-nano' structure confines gas molecules, increasing interactions with the graphene surface, and maintains breathability and flexibility.
A recent study published in Managing Sport and Leisure examines adult sideline behaviour in junior rugby league, finding that negative behaviors are increasingly normalized in older age groups. The research emphasizes the importance of establishing positive behavioral norms early in the junior pathway and challenges traditional approac...
A survey by the BfR Federal Institute for Risk Assessment found that mould toxins in food are not destroyed during cooking or baking. The survey also revealed gaps in knowledge about mould and its potential health risks, with many people unaware that mycotoxins can occur in food without visible signs of mould.
Researchers found OsSTP26 increases tiller number and grain yield by engaging distinct sugar-signaling pathways. The study identified OsSTP26 as a key link between source-to-sink carbon allocation and tiller development in rice.
Researchers at China Agricultural University have developed two novel Type I-C CRISPR systems, Aca I-C and Cja I-C, for efficient genome editing in maize. These systems enable targeted large-fragment deletion and expanded-window base editing, highlighting their potential for crop trait improvement.
Researchers found that calcium application strengthens stem structure and remodels cell wall components to improve lodging resistance and yield. The study demonstrated that calcium synergizes lodging resistance and yield potential in rapeseed by cell wall strengthening and photosynthesis.
Researchers found that sector labels in the S&P 500 only partially capture a company's financial situation. The study used machine learning models to group firms by financial similarity, revealing nine economically interpretable clusters that generally showed lower internal dispersion than conventional sectors.
New research from La Trobe University finds that injury or pain affects participation in social sport for one in five physically inactive women. Inactive women from lower-income households are more likely to be injury-affected, with knee, lower back, and ankle injuries being the most common complaints.
Researchers at the University of California San Diego used computational models and virtual reality to study the social interaction rules of schooling fish. They found that individual fish 'copy' the movement direction of a randomly-chosen nearby neighbor, leading to highly dynamic behavior in groups.
Researchers have identified a hidden defect in the gut that can damage intestinal cells, even in patients with well-controlled disease. The study found that this defect can be present in patients with clinically mild disease and can lead to future flares.
A multicenter study found that early rasburicase treatment can significantly reduce the risk of dialysis and death in adults with tumor lysis syndrome. The study analyzed data from 1,276 patients and showed that early rasburicase treatment was associated with lower 90-day mortality and faster return to cancer therapy.
Researchers at Columbia University have discovered a new type of cell that protects lung cancers from attacks by the immune system. The new cells, called CHL1 fibroblasts, promote lung cancer by recruiting regulatory T cells to the border of the tumor.
A new study found that US adults' interpretation of 'plant-based' diet differs significantly by age, with older adults equating it to veganism. The study, published in the American Journal of Lifestyle Medicine, analyzed data from 2,202 US adults and found that younger adults (18-34 years old) have a more nuanced understanding of the t...
A study found that 65% of young children brought to ERs for suspected poisoning didn't need emergency care, and could have stayed home with a phone call to the poison center. This could save millions of dollars nationally each year, as routing avoidable cases to the phone line could save $1,000 per visit.
This review synthesizes clinical and basic research progress on obesity and CVDs, exploring epidemiology, pathophysiology, and management strategies. The authors highlight the effects of obesity on various CVDs, emphasizing the need for effective prevention and treatment strategies.
A new study reveals that Parkinson's disease costs Europe €22.8 billion annually, with direct medical and non-medical costs, informal care, and lost productivity contributing to the total burden. The condition's prevalence in Europe has nearly doubled since 1990, with Germany recording the highest national costs at €5.7 billion.
A University of East Anglia report suggests that tens of thousands of new mothers in Britain may be suffering from undiagnosed PTSD after childbirth. The report highlights the need for better guidance and training for GPs to identify post-traumatic stress disorder symptoms.
A new study found that El Niño events have become nearly 40% stronger in the last 40 years than they were in the pre-industrial era. The researchers used coral reconstructions from the Galápagos Islands to examine historic El Niño patterns and confirm that the current El Niño event is superimposed on global warming, likely to superchar...
The DSTOX platform uses a multi-strategy fusion approach to integrate statistical rule-based models, expert knowledge rule-based models, and analogue search for mutagenicity assessment. The platform achieved an accuracy of 92.0% in internal validation and 84.0% in external validation, comparable to mainstream prediction tools.
A new clinical trial initiative aims to determine the best treatment strategies for older adults with acute myeloid leukemia, a life-threatening blood cancer. The five-year trial, led by Fred Hutch Cancer Center, will compare stem cell transplantation with non-transplant therapy for patients in remission.
SUNY Chancellor King visited the Great New York State Fair, showcasing participating SUNY campuses and offering free admission to current and incoming students. The event highlights SUNY's agricultural, healthcare, and technology initiatives.
Researchers discover a natural compound ascr#18 that primes plants to fight pathogens more effectively, increasing resistance without sacrificing growth and development. The treatment, effective in various crops, provides a promising solution for global food security and sustainability.
The Railway and Infrastructure Laboratory (RaIL) at Graz University of Technology allows for realistic testing of complete track systems, investigating load-bearing capacity and durability. This enables research into track structure interactions and the effects of environmental conditions on durability.
Scientists have developed a new acoustic levitation technique using an ultrasonic beam capable of levitating and moving small objects in mid-air over distances of up to 40cm. The technique, which uses a zero-order Bessel beam, enables stable levitation six times further than previously achieved using conventional methods.
Joachim Groß, a process engineer, has received an ERC Advanced Grant to develop an open-source system that combines empirical and physical models for predicting complex chemical processes. The system aims to overcome the limitations of current models and provide a high degree of precision for both science and industry.
Numerical experiments show that parameterization of orographic gravity wave drag reduces rainfall intensity overestimation and improves forecast accuracy. The study suggests current OGWD parameterization schemes require further improvements to achieve greater forecasting accuracy.
A Peking University team developed a homogenized gridded climate dataset for China, removing non-climatic signals from traditional meteorological observations. The dataset helps detect and attribute climate change, overcoming difficulties in correcting gradual and abrupt inhomogeneities.
A new study reveals a 3,307% increase in recreational drug ingestions among young children from 2000 to 2024, with most ingestions involving cannabinoids. The ingestion rate of marijuana edibles increased by 2,349% from 2015 to 2024, driven by the rapid growth of marijuana edibles and state legalization of cannabis.
A new study from the University of East Anglia found that people who swim in rivers and lakes are more than twice as likely to develop skin problems. Higher levels of bacteria linked to faecal pollution are also associated with an increased risk of stomach bugs. The study, which analyzed data from 2,368 volunteers, found that swimmers ...
University Hospitals has received American Heart Association Get With The Guidelines - Stroke awards for its commitment to ensuring timely, appropriate treatment for stroke patients. The hospital has achieved high levels of quality care, including door-to-needle times of 45 minutes or less for 75% of patients.
Researchers found that personalized content from social media algorithms can negatively impact users' mental health by reinforcing negative emotions and thoughts. The study suggests that educating people on critical social media engagement behaviors can help mitigate this effect.
A new study found that a more diverse plant-based diet is associated with lower BMI, higher HDL cholesterol, and better overall diet quality. Consuming a wider variety of plants per week was linked to improved gut microbiome scores and higher fibre intake.
A study by Yale University ecologists found that 16% of Mexico's habitat is covered by protected areas, but overlaps increase when including wildlife management units and Indigenous territories. The analysis highlights the need for a diverse mosaic of conservation areas to protect carnivores, with priority areas identified for expansion.
A new study reveals that pre-cancerous blood cells can actively reshape the bone marrow environment, creating conditions that favor their growth and increasing the risk of blood cancer. By targeting the aging bone marrow environment, scientists may be able to slow down or prevent blood cancers before they arise.
NY Creates will receive $1.25 million to support research, technology scaling, and workforce development in quantum computing. The institute aims to overcome significant barriers to practical quantum computing by developing techniques for fabricating hardware and education programs.
The partnership aims to advance additive manufacturing for critical energy challenges, including nuclear energy and broader energy infrastructure. SRNL and 3D Systems will jointly pursue advancements in materials development, equipment enhancements, and workforce development training.
Corals hosting heat-tolerant algae are more resistant to heat stress, but their immune systems are suppressed, making them more prone to disease. This trade-off helps explain why some corals appear more resilient but struggle to survive in complex environments.
A new clinical decision support tool, FRACTURE-ML, identifies people at high hip fracture risk using existing health registers and avoids patient-reported information. It has the potential to become an important tool for preventive care, potentially identifying nearly seven times as many people at risk of hip fracture.
New research explores monarch butterfly conservation in rangelands and the effectiveness of state regulations for controlling invasive species. Studies reveal that ungrazed pastures support more milkweed and monarch eggs than grazed sites, highlighting the need for selective approaches to conservation.
Researchers at CU Anschutz and Indiana University School of Medicine identified a biological process that explains how colorectal cancer can cause severe muscle and bone loss. Blocking the production of a protein called IGFBP1 helped preserve muscle and bone, improving muscle strength in laboratory and preclinical models.
Researchers at the University of Michigan found that older adults who experienced food insecurity in both midlife and later life had nearly four times the risk of probable dementia. Food insecurity was concentrated among those who experienced it later in life, rather than midlife alone, suggesting a strong association between later-lif...
Researchers created a self-stratified stretchable passive cooling interface that reduces temperature in wearable electronics. The interface, composed of aluminum-oxide-rich and liquid-metal-rich layers, combines external-blocking and internal-dissipation functions, improving cooling performance.
Pinoresinol diglucoside (PDG) attenuates diabetic cardiomyopathy by suppressing store-operated calcium entry and downregulating STIM1/Orai1/NFAT3 signaling pathway, ultimately inhibiting the progression of diabetic cardiomyopathy.
Quzhou Fructus Aurantii ethyl acetate extract (QFAEE) significantly ameliorates liver enlargement, lipid accumulation, and liver injury in MASH models. It activates the PPARalpha signaling pathway, upregulating CPT1A and downregulating lipogenic markers.
Researchers found that using the loose side of thin wood sheets as the tension surface reduces stress concentration and improves bending performance. This technique resulted in significant cost savings and waste reduction, making it an attractive alternative to traditional reinforcement methods.
A 2-year multicenter cohort study found that most hospitalized survivors maintained or regained cognitive function after Omicron infection, while older and reinfected patients may face progressive decline. The study identified age, infection history, and disease severity as risk factors for progressive decline.
Researchers developed a method to enrich EVs from whole blood, capturing complementary biological information lost in plasma or serum analysis. This approach may support deeper investigation of disease mechanisms and discovery of circulating biomarkers.
UM171 molecule helps retain stem cell properties, stimulating multiplication, and exploits protein KBTBD4 to break down important protein structure CoREST. This mechanism is also affected by mutations in KBTBD4 gene, linked to aggressive brain tumours in children.
MDS26 focuses on high-dimensional data analysis, scalability, and parallel algorithms, highlighting advances in mathematical and computational methods. Researchers and practitioners will engage with emerging ideas, share insights, and define the next generation of mathematics for data science.
Researchers demonstrate optical Magnus effect in trapped calcium ion, affecting laser control in quantum computers, with potential for complex computations and precise qubit coupling. The effect's magnitude depends solely on the wavelength of the light, not the laser's focus.
Researchers at Boston Medical Center and Boston University have developed a scalable method for generating CD4+ helper T cells from induced pluripotent stem cells (iPSCs), overcoming a longstanding challenge in the development of stem cell-based immunotherapies. This breakthrough could help advance efforts to create off-the-shelf CAR-T...
Researchers at MIT developed bifur-circuits, a new type of shape-changing smart device that can be reconfigured to form different shapes and maintain electrical connections. These interactive building blocks can be used to create adaptable smart devices, such as assistive furniture and reconfigurable robotic grippers.
Mayo Clinic joins a consortium to develop affordable, scalable gene-editing therapies for children with rare inherited immune disorders. Researchers will use CRISPR-based technologies to repair disease-causing errors in blood-forming stem cells.
A new UC Irvine study suggests that social media posts can reveal where Californians may be most vulnerable to extreme heat. Researchers analyzed 24,598 heat-related posts on Twitter, finding correlations between housing, transportation, and life impacts on the effects of heat.
The conference focuses on mathematical issues in imaging, expanding its reach in science and medicine. Challenges span multiple disciplines, including physics, engineering, mathematics, and data science.
Scientists at UCSF QBI mapped 1,800 protein interactions across 100 autism risk genes, revealing how diverse genetic mutations converge on shared molecular pathways. The study provides a framework for designing medicines that target multiple genetic forms of autism simultaneously, offering advantages in brain delivery and tolerability.
Researchers found that theta oscillations during learning predicted which experiences were remembered after sleep, and this pattern was associated with better memory performance. The study suggests that the brain may use theta oscillations to 'tag' experiences for later memory consolidation during sleep.
Researchers at the University of Toronto have developed a next-generation RNA therapeutic approach that can treat a wide range of genetic diseases by helping cells read through premature stop signals. The approach, centered on transfer RNA, has shown promise in laboratory and preclinical models of cystic fibrosis, and may be combined w...
A machine-learning tool built from Swedish national health registry data can predict hip fracture risk with high accuracy and identify individuals at high risk without in-person assessment. The tool performed nearly seven times better than current screening methods in identifying at-risk individuals.
A University of Michigan study found that El Niño events have become nearly 40% stronger in the last 40 years than in the pre-industrial era. The study, which examined modern and ancient corals in the Galápagos Islands, found that El Niño events in the last four decades were stronger than any in the 1,000 years prior to about 1850.
Researchers analyzed 22 gecko species to track sex chromosome origins in real time, revealing a 'sex chromosome birth pulse' linked to climate disruption. Geckos' diverse sex chromosomes are influenced by climate, genomic predisposition, and selective pressure.
The grant will support QBI's role in ARIA's Protein-Protein Interactions Hub, mapping disrupted protein complexes and developing mechanism-based small molecule medicines. The work aims to move from fundamental science to therapeutic discovery for people with autism and others on the spectrum.
The 2026 vehicle emissions standard rollback is founded on faulty assumptions, according to a recent study. The analysis hinges on incorrect valuation of fuel savings, which results in billions of dollars in benefits being removed from vehicle emissions standards. A new framework for translating consumer behavior into cost-benefit anal...
Researchers found that 92% of magnitude-3-or-greater injection-induced earthquakes were preceded by detectable foreshocks. Foreshock productivity and patterns reflect the interplay between fluid injection, seismogenic index, and fault stress state.
A new therapy using chemically enhanced suppressor tRNAs and lung-targeted delivery restores CFTR protein production and function in models of cystic fibrosis. The approach overcomes challenges of inefficient readthrough and immunogenicity, offering a promising treatment for the genetic disorder.
A 1,000-year record from Galápagos corals shows El Niño is intensifying due to climate change, with ENSO variability 37% higher than during the preindustrial era. This increase in El Niño events poses growing risks to ecosystems, infrastructure, and human societies.
Researchers at the University of York have uncovered the neural mechanism that instructs the brain to prioritize and strengthen important memories during sleep. This 'tagging' mechanism, linked to a specific brainwave pattern, helps the brain filter out irrelevant details and retain key experiences.
Researchers discovered that SGLT2 inhibitors activate PANK1, a key enzyme that boosts energy production and improves heart function in heart failure patients. Increasing CoA production improved the ability of human heart cells to contract and relax, two critical functions impaired in heart failure.
A new stepwise evaporation method called Step-Eva has been developed to reduce contact resistance in transistors. This process enables the direct in situ growth of single-crystal metal films on semiconductors, promoting atomic diffusion and facilitating lateral domain coalescence. The resulting single-crystal metal contacts exhibit low...
The conflict in Iran is driving people away from fossil fuels, with the world less economically reliant on them. Effective solutions include deep investments in clean energy, public transportation, and urban planning, as well as emergency measures like cash transfers and targeted assistance for low-income households.
Researchers trained AI on stick insect walking cycle to find optimal walking strategy, resulting in a six-legged robot that can navigate treacherous terrain and adapt to missing limbs. The approach allows for cheaper and faster robot production, enabling potential disaster response applications.
A research team tracked the crystallization process of HZO thin films in real-time, revealing that oxygen vacancies affect the material's performance. Films with fewer oxygen vacancies crystallized at lower temperatures and formed the ferroelectric phase required for information storage more favorably.
A team of researchers observed a fish-prawn hybrid, Scalicus engyceros, walking backward in the deep sea. The creature's unique features, including its pectoral-fin rays and barbels, enable it to sense prey and balance during walking and swimming.
Researchers have estimated that the unknown absorber in Venus's clouds must absorb light very efficiently, occur at a high concentration, or both, with a required decadic absorption coefficient reaching approximately 1,278 cm-1 at 375 nm. This suggests that highly absorbing conjugated organic molecules could be the culprit, but the stu...
The SIBAF project at GSI/FAIR aims to develop innovative fusion materials and accelerator technology for future fusion power plants. The €9.7 million funding will support the creation of a unique accelerator-based infrastructure for rapid material qualification.
A team of scientists developed a high-throughput platform to fabricate optical neural networks at visible wavelengths, achieving record speeds and low energy consumption. Four million neurons were printed on a millimeter-scale chip in just 15 minutes.
Researchers developed graded membranes to separate complex hydrocarbons mixtures into valuable products. The strategy demonstrated molecular-level fractionation of light naphtha, achieving a recovery rate of 85-90% and reducing energy consumption by 91% compared to conventional distillation.
Researchers at Charité report significant success in treating severe rheumatoid arthritis with CD19 CAR T cells, reducing disease activity and promoting sustained remission in patients. The treatment targets disease-driving B cells, allowing the immune system to reset and eliminate harmful antibodies.
The MDPI Subject Workshop: Microelectronics, Microsystems, Sensors, and Their Applications will explore a broad range of topics, including microelectronics, microsystems, sensors, and their applications. Researchers and industry professionals will gather to exchange knowledge and discuss emerging technologies.
The integration of carbon dots with nanowires overcomes aggregation issues, enabling precise spectral filtering and optical confinement for enhanced photoluminescence. This scalable host-guest architecture offers a powerful platform for nanophotonic light sources in sensing, communication, and quantum technologies.
A review by Professor Di Wang and Dr. Zheyu Chi proposes a conceptual framework in which immunometabolism is shaped by the local repair niche, influencing tissue repair trajectories. Organ-specific metabolic microenvironments uniquely shape immune cell function, necessitating targeted therapeutic interventions.
A team of scientists has successfully synthesized four distinct topological architectures, including a molecular-tweezer-like compound and an 8<sub>18</sub> knot, through coordination-angle-controlled self-assembly. The research establishes a novel platform for developing functional materials with exceptional photothermal conversion pr...
A new study examines death-related conceptual metaphors employed by neurosurgeon Paul Kalanithi in his memoir, shedding light on how he depicted death after being diagnosed with stage IV lung cancer. The research reveals that Kalanithi predominantly conceptualizes death as a transition or movement, followed by a negative presence.
Researchers at JAX-NYSCF will create and share human stem cell models to better understand Parkinson's disease development. The team aims to create a shared platform of rigorously validated models, data, and protocols to accelerate therapeutic discovery.
Researchers developed a microneedle patch that can detect early signs of kidney injury, stabilizing biomolecules in high-heat settings. The patch, coated with a metal-organic framework, preserves NGAL antibodies, a clinically validated biomarker for kidney damage.
A new study by ZOE found that 83% of participants lost weight in 12-15 weeks by following personalized food advice, without relying on calorie counting or restrictive dieting. The average weight loss was 3 kg, with 34% achieving a 5% body weight loss, considered clinically meaningful.
Wei Xu, a Marshall University researcher, has received two NIH grants to investigate new approaches for combating antibiotic-resistant bacterial infections. His projects focus on CAUTIs and Group A Streptococcus skin infections, with potential breakthroughs in biomarkers and therapies that prevent biofilm formation.
Researchers developed packing models that incorporate item priority, location, and weight distribution to optimize spatial usage and improve efficiencies in logistics and storage. The models provide fast and high-quality solutions to packing challenges in military and real-world applications.
A new study casts doubt on a leading theory linking dark matter and stellar streams, revealing that the host galaxy itself plays a significant role in shaping these streams. The simulations show that the structure of the galaxy causes irregularities in the streams, which could be mistaken for dark matter's gravitational tug.
Researchers have provided the first experimental evidence that strong magnetic fields surrounding active stars can completely suppress coronal mass ejections. This discovery helps explain why CMEs are rarely observed on stars other than the Sun.
When multiple evolutionary paths are equally advantageous, organisms tend to drift toward flatter regions of the evolutionary landscape, favoring traits that provide greater robustness and tolerance. This suggests that biological robustness and resilience can emerge spontaneously through evolutionary dynamics.
Portland State University has been awarded a $5.9 million NSF grant to accelerate research translation and strengthen the regional economy. The grant aims to close the gap between research strength and industry needs, with a focus on artificial intelligence, semiconductors, and transportation.
Researchers used AI to solve a decades-old fluid mechanics problem in five weeks, but found that the AI made subtle errors along the way. The breakthrough could improve how scientists study nanoparticles, but highlights the need for careful validation of AI-generated work.
NeuroSyn decodes movement intentions and tracks nerve recovery in real-time, capturing continuous recovery dynamics. The device achieves high signal-to-noise ratio and accurate motor intention decoding, making it a potential tool for exoskeleton-based rehabilitation.
Researchers from KTH Royal Institute of Technology developed a novel technique to manufacture nanoscale sensors, allowing for mass production in conventional semiconductor plants. The method, likened to uprooting a tree stump, creates nanopores in thin membranes for DNA analysis and molecule detection.
Researchers used directed evolution to boost bacterial tolerance to industrial spray-drying, improving survival by 1000-fold. The genetic basis of this newfound toughness was linked to a mutation in the pepC gene, which truncates the protein and likely abolishes its enzymatic activity.
Researchers have documented glycan-glycan interactions between gangliosides and their impact on EGF receptor dimerization and activation. This study provides a new mechanism regulating EGFR activity, which may have implications for future cancer research.
Transparent ferroelectric ceramics face trade-offs between transparency and functionality due to multiscale structural features. Strategies such as pressure-assisted sintering, grain refinement, and domain engineering can reduce optical scattering, but may alter polarization switching, piezoelectric activity, and thermal stability.
Phosvitin phosphopeptides from chicken egg yolks demonstrate strong antioxidative and neuroprotective effects, reducing ROS and increasing cell viability in SH-SY-5Y cells. Further research is needed to confirm their value as potential food/nutraceutical ingredients and determine their dosage and safety in humans and animals.
Researchers found that a combination of sucrose and supercritical carbon dioxide can improve egg white protein foam's foaming ability and stability. The treatment increases foaming capacity and preserves stability, enabling better freeze-thaw resistance in liquid egg white products.
A study published in JAMA Network Open reveals that nearly 1 in 3 women in their 20s have never been screened for cervical cancer, with 45% of this age group unvaccinated against HPV. The trend is particularly concerning among uninsured women, those living in the South, and racial minorities.
A low-carb ketogenic diet was found to improve liver health and blood sugar control more significantly than other diets, reducing liver fat by 67% and lowering blood glucose measurements by 20%. The study suggests that weight loss alone is not enough to combat metabolic health risks and that dietary choice remains an important factor.
A clinical trial found that a ketogenic diet significantly improves metabolic health in people with obesity, with 50% of participants no longer meeting the criteria for prediabetes. The diet also showed the greatest improvements in liver health and insulin sensitivity.
A UCLA study found that patients with cancer who used biosimilars had lower average monthly costs for insurers and patients, with savings of $3,820 for insurers and $39.50 for patients. The study also found that biosimilar entry led to lower prices and declining market share for the original branded biologic drugs.
The study found that cervical cancer screening rates among US women increased for both age groups 21-29 years and 30-65 years between 2005-2023. Sociodemographic disparities were also identified in the study, highlighting the need for targeted interventions to improve screening rates among underrepresented groups.
A quality improvement study found that a publicly available MRSA prevention program toolkit materials were associated with a 65% decrease in hospital-onset MRSA bacteremia laboratory-identified events. The study included 106 ICUs and 87 non-ICUs from 94 hospitals and involved a 2.3 event reduction per 10,000 patient-days
Researchers have developed a genetic toolkit to isolate individual neuron types in a fruit fly brain, revealing distinct neuronal subgroups that produce different effects, including suppressing aggression. The study identifies a universal control of aggression across sexes and highlights the complex roles of neurons within the same neu...
Researchers have developed a vehicle-mounted spectroscopy system that can reliably detect methane in real time while driving. The system uses mid-infrared dual-comb spectroscopy to detect gases and can be used to locate hidden methane emissions across large areas.
Native Hawaiian women have the highest breast cancer incidence in the US, with a 27% higher rate than White women. The American Cancer Society report highlights the need for tailored interventions to address cancer disparities among Asian American and Native Hawaiian and Pacific Islander populations.
A study found that AI analysis of mammograms can identify features indicative of hypertension, ischaemic heart disease, and stroke in women. This could lead to early detection and prevention of cardiovascular diseases in midlife women who undergo routine breast cancer screening.
A new study suggests that machine learning models using first-trimester pregnancy data can identify women and babies at risk of serious health problems earlier and more accurately than existing early risk assessment approaches. The models generally outperformed the current methods in Sweden, Chile, and Singapore, highlighting the poten...
Researchers found that scented cleaning products form nanoparticles in the air, which can travel deep into the lungs, posing respiratory risks. The particles are formed quickly, taking just minutes to form and grow, and can pose health risks even after cleaning is completed.
Parasitic plants, such as dodders, steal genes from other plants and remodel them over time, retaining their original function. This process, known as horizontal gene transfer, allows the plant to adapt and survive, with the gene becoming an integral part of its genome.
A comprehensive guide to the native reptiles of the Turks and Caicos Islands has been published after 20 years of collaborative fieldwork. The guide documents 11 native species, eight of which are found nowhere else on Earth, and includes original photographs, distribution information, and conservation assessments.
A team of scientists discovered that fleeting sugar pairings in cell membranes regulate epidermal growth factor receptor signaling, reducing unwanted cell division and potentially inhibiting cancer growth. This new mechanism reveals the importance of transient molecular interactions in maintaining membrane stability and regulating cell...
A protein that sticks cells together has been found to also help engulf dead cells, a discovery that could lead to new clues for understanding chronic inflammatory conditions. The study found that the 'tissue glue' helps cells adapt to swallow dead cells, which are a major cause of inflammation.
A new multi-ancestry polygenic risk score (PRS) for Alzheimer's disease (AD) outperforms previous models, especially in genetically diverse groups. The PRS was associated with cognitive decline, memory performance, and brain imaging traits, providing a more accurate prediction of AD risk.
A new guideline from the American Stroke Association emphasizes the importance of early, individualized rehabilitation to help survivors of stroke regain independence and quality of life. The comprehensive approach addresses physical, cognitive, communication, and emotional challenges throughout recovery.
NYU Langone Health has appointed Sunil Rao, MD, and Susheel Kodali, MD, as directors of the Leon H. Charney Division of Cardiology and interventional cardiology, respectively. Dr. Rao will oversee a nationally ranked cardiology program, while Dr. Kodali will lead the Cardiac Catheterization Laboratory and expand treatment options for p...
Researchers at Ritsumeikan University developed a unique 'cut-to-fuse' strategy for molecular skeletal editing, transforming hydroxycoumarins into coumaranones under mild conditions. The method, published in JACS Au, demonstrates a new route to molecular scaffold construction, offering a valuable tool for medicinal chemistry.
Seoul National University researchers use probabilistic fracture mechanics to assess pipe rupture frequency in nuclear power plants, accounting for degradation mechanisms and individual parameters. The study highlights the importance of inspections in reducing rupture frequency, and the results can help engineers identify key factors g...