Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
Cardiologist George Dangas, MD, PhD, is recognized for his lifetime achievements in caring for patients and cardiology education. He is the third interventional cardiologist from Mount Sinai to receive the Laennec Master Clinical award, which celebrates his exceptional insight in correlating cardiovascular disease with clinical findings.
Researchers are studying how microgravity affects colorectal tumor response to chemotherapy on the International Space Station. They aim to learn how to improve cancer patient care on Earth by applying knowledge gained in space to treat tumors more effectively at lower doses.
A $2M grant from the National Science Foundation will support professional development workshops and active learning initiatives for STEM educators at SUNY campuses. The project aims to address the challenges of traditional lecture-based learning and promote a more effective, student-centered approach to STEM instruction.
Researchers have developed a new approach called agentic robotics, which enables teams of AI agents to generate, test, and refine robot programs quickly and efficiently. This method addresses the challenges of collecting and processing large amounts of data and programming robots, allowing for faster and more adaptable robot development.
A study by Ohio State University researchers found that people view 'kind' and 'nice' as essentially interchangeable, but 'caring' is a higher threshold. Acts that are warm, planned, and not expected of the giver are consistently rated as more prosocial.
SourceOhio State University·JournalInternational Journal of Applied Positive Psychology·TypeExperimental study
A phase 2b clinical trial led by Mass General Brigham researchers shows that MAR001 can significantly reduce triglyceride levels within 12 weeks for patients with high triglyceride levels. The therapy targets ANGPTL4, a protein that naturally inhibits lipoprotein lipase, an enzyme that breaks down triglycerides.
SourceMass General Brigham·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial
Researchers propose that childhood cancers may spread aggressively by 'shape-shifting' into different cellular states, rather than accumulating genetic mutations. This process may be reversible, and understanding these transitions could lead to new treatment opportunities and potentially predict when cancers are preparing to spread
A new study by ISGlobal estimates that very strong El Niño episodes are associated with 107,035 additional heat-related deaths and 112,681 fewer cold-related deaths per year compared to neutral conditions. This shift towards warmer temperatures during El Niño has significant implications for global health.
A new study by Stanford Medicine scientists found that linear acceleration, not rotational motion, is more predictive of concussion. The research analyzed data from motion-sensing mouthguards and found that peak linear acceleration is the single most predictive factor in whether an impact leads to concussion.
SourceStanford Medicine·JournalAnnals of Biomedical Engineering·TypeExperimental study
Scientists have developed a treatment that 'reawakens' heart muscle cells, promoting repair and improving heart function after a heart attack. The treatment, using mRNA therapy, temporarily activates proteins that help regenerate heart tissue, leading to a stronger heartbeat and increased blood pump efficiency.
Researchers found that tiny plagioclase crystals from Andean volcanoes have the same chemical signature, indicating the same eruptive process. This discovery could help predict future eruptions by analyzing the crystals' composition, which is linked to hot magma from deeper underground.
Scientists at Tampere University develop a new approach to composite fillers, designing each particle's 3D geometry before printing, enabling tailored stiffness and mechanical behavior. The new method could lead to breakthroughs in soft robotics, biomedical materials, and tissue engineering.
A new AI tool, PREVIA, analyzes patients' narratives about injuries to predict who will later develop PTSD, correctly identifying over 95% of at-risk patients. This tool could help clinicians catch the condition early, as it is designed to be a quick and efficient screening method.
Researchers will study icy lunar soil's cohesion, flow behavior, and mechanical properties under cryogenic conditions, providing insights for extracting water ice and other resources. The project's findings could help inform methods for handling and processing lunar regolith.
A new study reveals that participating in cancer clinical trials can cause financial burdens, with median reimbursement of $2,128. The study suggests that reimbursement programs can improve equitable access to and retention in trials, making cancer clinical trials more accessible.
SourceWiley·JournalCancer
A study by the University of Plymouth found that international regulations governing marine protected areas (MPAs) are often ambiguous, failing to provide clear rules for satellite-based enforcement. This limitation hinders the effective use of satellite monitoring to prevent illegal activities, such as industrial fishing, in MPAs. The...
PeroCycle has announced a partnership with Glass Futures Ltd to develop a scaling platform for its closed loop carbon recycling technology. The technology uses a perovskite catalyst to split CO2 into CO, reducing carbon emissions from foundational industries by up to 90%.
Researchers found that despite mass ritual sacrifices, everyday violence was extremely rare in ancient Lambayeque Valley communities. The study suggests that societies may respond to climate change in diverse ways, and that violence is not a predetermined outcome.
SourceFrontiers·JournalFrontiers in Environmental Archaeology·TypeObservational study
Researchers discovered NGR1's neuroprotective effects are mediated by microglia-mural interactions and a FOXO1-associated program involving ABCA9. This study provides single-cell resolved insights into NGR1's mechanism and identifies potential therapeutic targets for cerebral blood flow regulation.
Researchers at the University of Tokyo used a new radiocarbon analysis technique to study ocean sediment cores, revealing previously undetected history of geophysical disasters in Japan. The study found multiple 'hidden' traces of earthquakes in the Nankai Trough, which could help predict future geophysical events and prepare for poten...
Researchers found that H3mm15, a histone variant differing from H3.3 by three amino acids, contributes to normal sperm development in mice by regulating gene expression. The study found that H3mm15 forms less stable nucleosomes, leading to changes in chromatin behavior and gene regulation.
The CT scans of Jeremy Bentham's head have provided valuable insights into his life and after-life, showing that he suffered from chronic toothache and a jaw riddled with arthritis. The scans also reveal further physiological factors, such as tissue structure and preservation choices, which were previously unknown.
Phase 3 clinical trials involving over 1,000 participants found that those taking retatrutide, a new experimental weight-loss injectable drug, lost about a quarter of their body weight on average and experienced significant pain relief. The drug also showed benefits in reducing blood pressure, lipid levels, and systemic inflammation.
A new study found that using portable air filters with high-efficiency particulate air (HEPA) filters can reduce daily blood sugar swings and morning sugar surges in people with prediabetes. By cutting levels of tiny air particles by 36%, cleaner air was linked to a nearly 8% drop in blood sugar swings and smaller morning surges.
A randomized trial found that intravenous iron repletion led to functional benefits after 12 weeks for patients with HFpEF and iron deficiency. Peak oxygen uptake improved by approximately 10% in the intervention group.
Researchers found that intravenous cangrelor improved heart function in cardiogenic shock patients, with a 73% lower risk of microvascular obstruction compared to oral ticagrelor. After one year, cangrelor patients showed a significant increase in heart pumping ability, outperforming ticagrelor.
A new treatment, extended aldosterone synthase inhibition (EASI), has been shown to reverse excess aldosterone production and lower blood pressure in people with primary aldosteronism. The treatment, which involves taking a new class of drugs for 6-12 months, has been found to sustain its benefits for up to two years after treatment en...
A global phase 3 clinical trial, ZEUS, tested a drug targeting interleukin-6, but found no reduction in cardiovascular event rates compared to placebo. The study's neutral findings suggest moving upstream to find the right target, while acknowledging the effectiveness of downstream IL-6 inhibition in modifiable earlier stage disease.
SourceMass General Brigham·JournalNew England Journal of Medicine·TypeRandomized controlled/clinical trial
A new study has found that routine invasive procedures for stable heart disease do not improve long-term survival compared to drug therapy alone. The study, which followed over 5,000 patients with stable coronary artery disease, revealed that early invasive procedures eased symptoms and improved quality of life but did not reduce the r...
UT MD Anderson and P-Cure collaborate on a compact upright proton and helium ion therapy platform, combining expertise in radiation oncology and particle therapy. The alliance aims to establish the clinical value of helium ion therapy and advance the platform's capabilities.
Researchers found that charged states on carbon nanotubes, known as trions, retain their chirality, which is crucial for manipulating light and electric current in nanotechnology. This discovery opens new paths for quantum optics and potential applications in next-gen optoelectronic devices.
A randomized controlled trial found that Tai Chi Qigong and an exercise class improved sleep quality in older male cancer survivors, with no significant difference between the two. While the changes were modest, the study suggests that a more diverse range of participants and future studies are needed to confirm the findings.
SourceGenomic Press·JournalBrain Medicine·TypeRandomized controlled/clinical trial
A recent study published in Genomic Psychiatry analyzed the Alzheimer's Disease Neuroimaging Initiative and found that people with frequent anxiety scored lower on a standard test of global cognition. The authors suggest that a single serotonin receptor may be responsible for both worry and cognitive decline in Alzheimer's disease.
The employment-to-population ratio for people with disabilities held near record highs at 39.9% in October, reflecting sustained labor market growth. The employment-to-population ratio for people without disabilities also increased slightly, while labor force participation rates for people with disabilities decreased slightly.
Researchers at Texas A&M AgriLife Research used an AI tool to screen 1,100 human mitochondrial proteins for likely interactions, revealing nearly 2,900 new pairs. The study provides clues about the functions of mystery mitochondrial proteins and their roles in human diseases.
A University at Buffalo-led team has predicted the optical fingerprints of known atomic defects in hexagonal boron nitride, a material with potential applications in quantum technologies. The researchers' computer models simulated how different defects affect the intensity and polarization of light produced when h-BN is hit with a laser.
Researchers found that stock market analysts generally fail to adjust their price targets after Fed meetings, resulting in increased prediction inaccuracy. The study highlights potential limitations in how capital market intermediaries interpret and act upon macroeconomic information.
Alliance Clinical Trials is advancing early detection, improving treatments, and enhancing survivorship for lung cancer patients. The organization is conducting seven active clinical trials focused on prevention, early detection, treatment, and survivorship.
A Mount Sinai study found a single amino acid difference between rodent- and human-derived Andes virus isolates affects viral protein processing and release in human cells. The change enables faster virus-like particle release and altered protein behavior, providing a starting point for studying the virus's biology.
Researchers developed new instruments to assess empathy and Theory of Mind in everyday life, including positive and negative social contexts. The tools, EmpaToM-pos and EmpaToM-embarrass, provide a more precise understanding of human social understanding and its applications in clinical practice.