Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A phase 3 study found that combining belzutifan with pembrolizumab after surgery significantly improved disease-free survival for high-risk kidney cancer patients. The regimen reduced recurrence by 28% and kept 81% of participants cancer-free.
Researchers have identified three distinct distribution patterns of alkali metal cations at the reaction interface, which correspond to electrostatic adsorption, specific adsorption, and quasi-specific adsorption. The team clarified the physicochemical origin of the alkali metal cation effect and proposed new insights for designing nex...
Researchers at Tokyo Metropolitan University have created a rotating tabletop device to test dynamic wireless power transfer for electric vehicles. They successfully replicated conditions of a car moving at 40 kilometers per hour, promising accelerated research into next-gen charging.
A $3 million NIH grant funds a national study on Medicare Advantage's new non-medical benefits, including groceries, meal deliveries, utilities, transportation, and other services. The study will examine the impact of these benefits on health care use and patient outcomes.
Researchers found that managed cropland soils produced the highest nitrous oxide emissions due to irrigation and fertilization, while natural ecosystems emitted lower amounts but showed a clear response to elevation. Climate change could shift the balance of greenhouse gas emissions across ecosystems in arid mountain regions.
The company's CAP-accredited laboratory performs the PanCystPro assay, which utilizes proprietary BioMatra optical reporter platform to help clinicians accurately rule out malignancy in pancreatic cystic lesions. Amplified Sciences' lab has also validated its unique protease turnover assays through CAP accreditation.
Dr. Gregory Reeves' team has developed a method to measure the amount of Dorsal protein in the nucleus, revealing its interaction with DNA and providing a predictive model for therapeutic purposes. The study aims to control cellular processes and prevent diseases like cancer.
The award recognizes the exceptional achievements of graduate students exploring topics like tumor metabolism and DNA replication. The recipients reflect the strength and promise of the next generation of scientific leaders.
A review of field studies found that combining biochar with other amendments like compost, manure, or fertilizers enhances soil health by increasing water retention, nutrient cycling, and microbial activity. The co-application approach also improves soil physical properties and biological responses.
Renowned cancer clinician Dr. Daniela Matei will lead the Houston Methodist Dr. Mary and Ron Neal Cancer Center, bringing expertise in ovarian cancer treatment and therapeutics. She aims to bridge laboratory science to the clinic, advancing new concepts from bench to bedside.
Researchers found that adding native forest litter rapidly reshaped soil microbial communities and improved their functional potential. This low-cost strategy could help accelerate ecological recovery in degraded landscapes worldwide.
Researchers have developed a new PSMA-targeted PET tracer that shows promise in early human studies, providing strong tumor uptake and favorable radiation dosimetry. Additionally, advanced dynamic PET imaging has been used to track heart amyloid buildup more precisely, detecting significant reductions after six months of tafamidis ther...
The UT Health San Antonio School of Dentistry has secured a $9 million NIH grant to develop a targeted, non-opioid treatment for chronic pain associated with muscle and joint dysfunction. Researchers will map the biology of facial pain, identify specialized neurons, and analyze gene expression changes to design effective treatments.
A new targeted PET/CT tracer can detect treatment response in rheumatoid arthritis patients as little as four weeks after treatment initiation. The imaging technique uses macrophages, a type of white blood cell, as a biomarker for disease activity, potentially allowing non-responders to pursue more effective therapies.
Researchers identified an enzyme called PFKM, which helps control glucose processing in cells. By manipulating PFKM levels, they accelerated muscle building in laboratory models, potentially helping address age-related muscle decline and lean muscle loss in patients using weight-loss medications. This finding could lead to the developm...
A global study synthesizes evidence on dementia inequities in Indigenous communities, highlighting their cultural strengths as neuroprotective resources. The authors recommend centering culture and community in brain health research to promote lifelong equity and strengths-based models of dementia care.
A new study by engineers at the University of Colorado Boulder found that dopamine influences movement speed, particularly when rewards are expected. The researchers discovered that people tend to move faster towards targets that offer rewards and experience a surge in energy when they receive unexpected treats.
Seq-Scope-eXpanded allows researchers to see even finer transcription detail, enabling discoveries that weren't possible with previous methods. The technology has been expanded to capture transcriptome from tissue with greater resolution.
A gene therapy platform successfully mapped the living brain noninvasively, using engineered proteins to track gene expression in different brain regions. This technology has the potential to reveal critical information about cellular activity and neurological disease progression.
Drs. Guillermo Aguilar, Heng Pan, Xingyong Song, and Stavros Kalafatis recognized for their innovative technologies that have made or aim to make a significant impact on the welfare of society. The National Academy of Inventors Senior Member induction ceremony will take place in Los Angeles this June.
Researchers at Ohio State University have developed a new laser 3D printing method that can create extremely durable structures using simulated lunar dirt. The study found that the material's properties depend on the surface onto which it is printed, and that environmental factors such as oxygen levels and temperature affect its stabil...
A study by UCL researchers found large variations in nitrous oxide use across UK dental services, with some sites emitting up to 1,849 kg CO₂e per week. The team recommends reducing wastage, standardizing practice, and considering alternatives to minimize environmental impact.
Researchers found the Cascadia Subduction Zone to be more active than previously thought, with signs of shallow earthquakes and fluid flow detected offshore. The study suggests variable fluid pathways could alter the behavior of large earthquakes on the fault, potentially influencing the severity of future events.
Researchers develop a new material that exhibits improved reversibility in its barocaloric effect, allowing for a wider temperature range and increased refrigeration capacity. The material combines neopentyl glycol and pentaglycerine with added pentaerythritol to reduce thermal hysteresis.
The European Medicines Agency has granted a positive opinion to Acoziborole Winthrop as a single-dose oral treatment for both early- and advanced-stage gambiense sleeping sickness in adults and adolescents. The medicine, co-developed by DNDi and Sanofi, could provide a significant advance over current therapies.
A new study conducted by researchers at Penn State found that the presence of a higher variety of foods in a buffet increases both the weight and calories of food selected. Participants who visited buffets with more food options chose higher-calorie dense foods, leading to increased calorie consumption.
A UC Berkeley-led study reconstructed emissions from Swedish wildfires and found that current climate estimates are failing to fully account for carbon released from smoldering organic soils. This highlights the need for improved climate models to better understand the impact of northern wildfires on the environment.
The launch of Mauve marks a new era for astronomical data and collaborations, enabling researchers to study stars in ultraviolet and visible light. The satellite will investigate magnetic activity, stellar flares, and exoplanet habitability.
Leading climate scientists, including Prof Benjamin Santer, reiterate the role of humans in global warming and warn against using an inaccurate government report to inform legal decisions. The report's claims are factually incorrect, contradicting decades of research on human-caused temperature changes.
Study by Duke engineers reveals that a common device architecture used to test 2D transistors overstates their performance prospects up to sixfold. The back-gated architecture amplifies the transistor's performance using contact gating, but has physical limitations that prevent its use in commercial technologies.
The Safeguard project, which aimed to expand understanding of declining wild pollinators, has come to an end. The project delivered a comprehensive reassessment of European wild pollinator trends and developed an integrated assessment framework to guide evidence-based management.
Researchers found that circulating tumor DNA can predict metastatic risk in patients treated with bladder-sparing treatment for muscle-invasive bladder cancer. The absence of ctDNA predicted favorable outcomes regardless of bladder removal status.
A comprehensive review argues that single-factor interventions in Alzheimer's disease are insufficient due to the complex interplay of multiple factors. The authors call for an integrated therapeutic approach, including multi-target therapies and precision medicine based on early biomarkers.
Researchers found that past actions have a greater impact on current decisions than assumed, with people often repeating choices due to mental shortcuts. This study enhances understanding of everyday habits and decision-making processes, offering new starting points for describing human behavior more realistically.
A modelling study suggests that reduced international donor funding increases the household economic burden of tuberculosis in low- and middle-income countries. The research found that decreased funding leads to a significant rise in healthcare costs and lost productivity.
A partnership between Goethe University Frankfurt and Universidad de Costa Rica aims to deepen scientific understanding of Costa Rica's biodiversity, with a focus on conservation. The €450,000 funding will support joint research initiatives, including pilot projects on fungal diversity and the establishment of a culture collection.
Developing high-performance Ni-rich cathode materials is crucial for achieving single-cell energy densities exceeding 400 Wh kg‑. A research team synthesized quinary full-concentration-gradient cathodes using an in-situ co-precipitation strategy, featuring a Mn-rich, Ni-poor surface and radially aligned primary particles.
Researchers developed a comprehensive database and trained machine learning models to predict catalyst performance. They discovered a zeolite catalyst with ultra-high initial ethene selectivity, achieving 100% methanol conversion and 87.6% combined ethene and propene selectivity.
A study by SWPS University researchers found that imagery-based techniques can significantly reduce fear of failure and negative emotions associated with childhood criticism. The techniques, including Imagery Exposure and Rescripting, helped participants reframe their memories and experience a lasting reduction in stress and anxiety.
Researchers found that microbes can use mercury sulfide nanominerals as an energy source, releasing volatile elemental mercury into the air. The study estimates that this process could release hundreds of tons of mercury per year, comparable to cement production.
A recent study by Penn State researchers found that tardigrades can adapt to simulated Martian soil, but some regoliths are damaging to their health. Washing the regolith with water can mitigate this impact, providing a potential resource for plant growth and protection against Earth contaminants.
A new study reveals major blind spots in global sustainable research, overlooking key strategies and sectors needed to address the environmental crisis. The study finds that sustainability researchers are neglecting potentially powerful actors, including civil society, and failing to assign clear responsibilities across sectors.
A new study found that teams that move the ball unpredictably across the full field tend to succeed more than those that confine their play to a few hotspots. The researchers used an information-theoretic metric called Spatial Event Distribution Randomness (EDRan) to analyze event data from top-tier football competitions.
Researchers found that as humpback whale populations recovered from whaling, the age structure shifted towards a more even distribution among older and younger males. Older males became increasingly successful at siring offspring compared to younger males, suggesting they need time to refine their singing and competitive tactics.
Researchers at KAIST have developed a technology that predicts atomic arrangement tendency of catalysts using artificial intelligence, leading to more efficient design of fuel cell catalysts. The zinc-platinum-cobalt catalyst secured both higher activity and superior long-term durability compared to commercial platinum catalysts.
Researchers propose a new method for dynamic polychromatic holography using polymer-stabilized chiral superstructures, achieving broadband and multichannel functions. The device can dynamically modulate light wavefronts, reconstructing high-quality full-color holographic images with reversible switching.
Researchers propose a scene-level passive high-precision polarization 3D imaging method, resolving challenges of discontinuous targets, absolute depth interpretation, and dynamic reconstruction. The approach achieves accurate true depth through integrating stereo vision and polarization, enabling scene-level high-precision 3D imaging.
A cross-sectional study of former American football players found prior participation to be associated with worse later-life cognitive and neuropsychiatric function. The findings support a dose-response association with years and level of play, providing context for clinicians and researchers assessing symptom risk among former players.
Researchers at Aarhus University have developed a technology to turn used rubber gloves into a material that captures CO2, offering a climate-friendly alternative to current methods. The process converts waste rubber into a CO2 adsorbent using a ruthenium-based catalyst and hydrogen gas.
A new Singapore-based project reanalyzes 35 years of weather records for Southeast Asia, aiming to improve weather forecasting and regional climate resilience. The project will train artificial intelligence to make more precise predictions, benefiting governments, aviation, and maritime sectors.
Researchers created a paper-thin 'metalens' that can change how it looks at the world with just a tiny electrical nudge. The device flips between two useful views, producing two small bright spots for depth sensing and keeping fine details sharp without refocusing.
A study reveals a regulatory pathway in melon that links transcriptional control to cell wall chemistry, leading to accelerated tissue softening and changes in fruit texture. Transcription factor CmbZIP11 is identified as a key regulator controlling pectin methyltransferase genes during ripening.
Researchers at the University of Texas at Austin have created a high-resolution 3D map of the Andes virus, a crucial step towards developing vaccines and treatments against hantaviruses. The new structure allows for the design of effective vaccines and antibody therapies.
A new AI design strategy transforms semitransparent solar cells into colorful, user-defined windows without compromising energy output. The technology enables up to 20% power generation increase while maintaining visual appeal, making it suitable for real-world applications in buildings, vehicles, and wearable electronics.
Researchers found widespread occurrence of tri-OPEs and di-OPEs in the Tibetan Plateau's terrestrial ecosystem. The study confirmed the trophic dilution behavior of OPEs along a representative food chain, with bio-transformation and metabolism playing key roles.
A study found that refugee and immigrant children have lower rates of emergency department visits for minor illnesses compared to their Ontario-born peers. The researchers attribute this to the healthcare-navigation support they receive during early settlement.
Researchers propose a novel space-time-coding metasurface that integrates energy harvesting, electromagnetic wave manipulation, and information modulation. This technology enables high-capacity transmission, multi-user access, and green communication, with experimental verification demonstrating superior energy efficiency.
A team from Monash University Biomedicine Discovery Institute has identified a tick-derived evasin that can bind to two major classes of chemokines, representing a novel finding in the field. This discovery opens up new opportunities to develop therapies that target chemokines driving inflammatory diseases such as RA and MS.
A comprehensive study of collagen supplements found benefits in skin elasticity, hydration, and osteoarthritis symptoms. However, there were no meaningful improvements in sports performance or muscle recovery, dispelling some myths surrounding its use.
Researchers have developed a hybrid integrated C-band high-precision tunable semiconductor laser based on thin-film lithium niobate, achieving a wide tuning range of approximately 51.8 nm and a tuning precision of 0.03 nm while maintaining narrow-linewidth characteristics. The design integrates Sagnac loop reflectors with multiple sets...