Brightsurf delivers daily science news discoveries, articles, and the latest scientific breakthroughs. Your trusted source for science news today, covering nature news, science & technology, and scientific discoveries from leading research institutions worldwide.
A new tool, ASAP, rapidly and reversibly turns autophagy on and off, confirming suspected targets, revealing new ones, and suggesting a link between protein building and breakdown. ASAP also targets nuclear pore complexes and protein condensates, shedding light on autophagy's role in maintaining cellular health.
Scientists at Curtin University's ICRAR node have linked mysterious radio pulses to an unusual star pairing: a dead star that spins every 8 minutes and a Sun-like star. The discovery breaks new ground, as radio pulses are typically observed in systems with smaller and cooler red dwarf stars.
A large study published in Scientific Reports found that people with irregular sleep-wake schedules may experience more severe symptoms of anxiety, depression, and loneliness. The study analyzed data from 23,000 participants and found that those with consistent sleep patterns had lower rates of depression and anxiety.
The INRS team has set a new world record in profilometry, capturing three-dimensional images at speeds of up to 150,000 frames per second. The C-BLIP technology enables visualization of transient phenomena in multiple fields, including mechanics, aerodynamics, and microfluidics.
A new research project aims to study the stability of Antarctic glaciers and their impact on sea levels. The project will investigate the processes that affect the stability of ice shelves, including ocean currents, temperature, and snowfall, to improve predictions of future sea-level rise.
A study by the University of Copenhagen reveals that climate adaptation policies unevenly distribute costs, with poor residents shouldering the most burden. The study highlights the need for fair payment models and improved governance to distribute costs more evenly across social groups.
A team of four researchers, led by Professor Tomás Ryan, will explore how the brain stores memories of immune and sickness experiences to make predictions about future challenges. The project aims to determine the effect of chronic inflammation during pregnancy on immune memory function and its impact on altered neural development.
Researchers aim to diagnose societal tipping points to bring Earth back within a safe operating space. By analyzing past transformations and current trends, the team will model how societal changes can bring about a sustainable future.
The Hebrew University of Jerusalem has been awarded a €10 million ERC Synergy Grant to study judges' role in defending democracy. The six-year project, JUSTGOV, will examine 48 supreme and constitutional courts across OECD countries, mapping how judges act as agents of democracy.
The review highlights how macrophages, Th17 cells, and regulatory T cells shift across disease phases, and how metabolic reprogramming intervenes. Persistent injury disrupts this balance, leading to chronic pancreatitis.
Researchers investigate how warming oceans affect marine food webs by analyzing copepod diet differences. The study reveals geographical variations in basal diets, with tropical and subtropical regions favoring bacterial and heterotrophic bacteria, while colder regions prefer eukaryotic microalgae.
Researchers at Linköping University developed an organ-on-chip model of head and neck cancer, demonstrating how tumours interact with surrounding structures and tissues. The model showed that cancer cells respond differently to the ECM material and blood vessels, and that nerves can influence tumour behaviour and pain.
A 75-year dataset reveals a stark continental divide in El Niño impacts, with Southern Brazil facing torrential rainfall and the North experiencing severe drought. Month-by-month planning can help target preparedness efforts and reduce vulnerability.
A systematic review emphasizes the need for emotional security, family relationships, and culturally sensitive support for children approaching the end of life. The review found that children's spiritual concerns and needs for connection with others are often overlooked.
A study published in Advanced Science reveals that TREM2+ macrophages contribute to immune dysfunction in endometriosis, compromising CD8+ T cell and NK cell cytotoxic behavior. Researchers identified TREM2 as a potential therapeutic target, suggesting new avenues for developing non-hormonal therapies for endometriosis.
Research from Osaka Metropolitan University reveals that climate change is affecting Japan's forests, leading to changes in tree composition and structure. The study found that warmer temperatures and increased precipitation are driving the decline of cold-adapted tree species and the rise of warmer-adapted species.
Dr. Egan shares crucial steps to prevent foodborne illnesses, including handwashing, proper cooking techniques, and handling raw poultry. He emphasizes the importance of vigilance and taking responsibility for protecting loved ones during the holiday season.
A new study identifies a mechanism in the environment surrounding tumors that drives the growth of triple-negative breast cancer, a particularly challenging cancer to treat. Researchers found that a type of microRNA transferred from fibroblasts surrounding tumors, miR-1290, promotes cancer cell proliferation by suppressing tumor growth.
A study finds a direct link between reduced winter sea ice in the Barents and Kara Seas and summer droughts in eastern Europe and central Asia. The researchers used historical records of sea ice and atmospheric conditions to find a mechanistic link between winter sea ice cover and summer drought risk.
Researchers discovered a unique symbiotic bacterium, Candidatus Abyssoplasma scotoplanesicola, in deep-sea sea pigs. The bacterium has a minimized genome but produces 'giant' proteins, which likely play a role in interactions with host tissues or bacterial aggregation.
A study found that metformin kills cancer cells by blocking a mitochondrial-cytosolic circuit that drains surplus NADH, reducing reductive stress. The circuit, involving pyruvate carboxylase, mitochondrial malate dehydrogenase, and malic enzyme 1, is a key player in cancer cells' ability to survive under metabolic stress.
Researchers demonstrate that sound alone can recreate the experience of hand movement in flowing water, with increased pitch enhancing resistance. The study's findings may inform the development of sound-based technologies for visually impaired individuals, providing an alternative to visual cues.
Researchers review post-translational modifications of p53, revealing a dynamic signaling hub that coordinates cell-cycle arrest, apoptosis, and DNA repair. Targeting p53 PTM regulatory networks may offer anti-tumor strategies, but multiple obstacles limit clinical implementation.
Researchers at NUS developed a catalyst-regeneration strategy to improve hydrogen production from ammonia. The new catalyst, Pt/Fe-NC, resisted oxidation and poisoning, sustaining production for over 2,000 hours. This breakthrough brings ammonia-based hydrogen production closer to practical applications.
A systematic review and meta-analysis of 40 studies found that people with type 2 diabetes are 53% more likely to develop Alzheimer's disease. The review estimated that 4.7 out of 1000 people with type 2 diabetes will develop Alzheimer's in a year.
Professor Hanjung Lee's new monograph introduces an innovative approach to linguistic meaning study, integrating AI with linguistic theory. The book reveals AI language models' systematic tendencies to favor more frequent meanings, potentially distorting semantic variation found in actual language use.
A new study reveals that the decline in thermogenic fat activity with age may explain why older people feel the cold more. The research suggests that restoring thermogenic fat activity could help understand and treat age-related metabolic problems, including obesity and type 2 diabetes.
A study from the University of Birmingham found that nearly 30% of ingested carbohydrates remain unavailable to fuel exercise in hot conditions. Despite heat acclimation, the mechanism stopping carbohydrate transfer into muscles was not alleviated.
The study found that a salt-triggered gel containing engineered Salmonella reduced tumour growth by shrinking tumours as well as free bacteria, cutting weight loss by 82% and reversing liver and spleen damage. The gel also delivered the bacteria to the tumours, avoiding poisoning, and showed promise in treating melanoma and other cancers.
Researchers develop flexible coating with microscopic cracks that amplify antibacterial power, killing 80% of bacteria within three hours. The coating, combined with electrical stimulation, creates an antimicrobial response that can be switched on when needed.
Pseudogenes contribute to the adaptation of vertebrates to new environments by inactivating genes that are no longer necessary. This process, known as pseudogenization, has been observed in whales, naked mole-rats, and hummingbirds, where it has helped these species thrive in different ecological niches. For example, the loss of the TL...
Urban green-up dates advance faster than rural green-up in 80.4% of Chinese cities, with cities pulling ahead by 0.37 days a year. Heat requirement, not warming, governs the urban-rural disparity in spring phenology advancement.
Researchers have successfully tested a 'living medicine' treatment in pigs, thinning biofilms of antibiotic-resistant Pseudomonas aeruginosa and reducing thickness by 40%. The treatment involves inhaling genetically modified bacteria designed to target biofilms on endotracheal tubes.
Researchers employ Cu-BDC-X MOFs as pre-catalysts to facilitate multicarbon product formation. Electron-withdrawing ligand modification strengthens CO adsorption, reducing the C-C coupling energy barrier and improving selectivity.
Experts warn that destigmatizing obesity campaigns by pharmaceutical companies, like Eli Lilly's
Pregabalin misuse rates in Australia have declined by 25% and 47% following media coverage and prescribing restrictions, with dispenses decreasing significantly in December 2018, May 2020, and December 2021. Despite ongoing concerns, the decline suggests similar interventions in other countries may be effective in reducing misuse.
A trial of older adults found pausing blood pressure medication on surgery day reduces the rate of very low blood pressure requiring treatment. The study provides high certainty evidence to inform future guidelines for patients aged 60 years or older with high blood pressure.
A study of 10,000 employees found that sit-stand desks increase active computer time by 43 minutes a day, resulting in 171 additional hours of work per year. This translates to a potential annual productivity gain of nearly $9,000 per employee.
Scientists have developed a molecularly woven fabric that can filter out most of the benzene in a mixture, separating it from cyclohexane with high efficiency. The fabric, made of four molecular networks, is reusable and can be used on an industrial scale, potentially reducing energy consumption and costs for the chemical industry.
The partnership aims to strengthen quantitative molecular imaging by promoting harmonized approaches to image acquisition, reconstruction, and analysis. By developing and implementing shared standards, the organizations seek to improve the accuracy and consistency of quantitative imaging results.