Chronic kidney disease patients with high blood phosphate levels may be at risk of progressing to kidney failure faster. Lowering phosphate levels could help optimize the effectiveness of important kidney medications like ramipril.
A University of Cincinnati study reveals that racial tensions played a significant role in Southern executions, with black audiences using these events as sites of resistance to oppression. The research found that white reporters portrayed the executions as 'just' and downplayed the conflict they sparked among black communities.
Memory T cells that initially developed against a virus upon first encounter can be lost during chronic infections, making it challenging for vaccine development. Researchers at the Emory Vaccine Center have identified a molecule called 2B4 on memory cells that slows them down during chronic infections.
A study published in the European Physical Journal B demonstrates that embryo development follows hydrodynamic principles, where cells flow like a fluid, resulting in the formation of the head. This challenges previous theories suggesting chemical gradients drive cell movement, providing new insights for regenerative medicine.
NASA satellite data shows strong convection in both Tropical Storm Fernanda and Hurricane Greg, making them match in size. Both systems are moving towards the western coast of Mexico.
A prevention program for postpartum obsessive compulsive symptoms was developed and tested in a study, reducing anxiety and symptom incidence in mothers. The program incorporated cognitive behavioral therapy principles and was found to be effective in preventing symptoms from developing.
The tammar wallaby genome sequence provides valuable information on the evolution of mammalian reproduction, development, and fascinating biological characteristics. Researchers discovered genes responsible for the kangaroo's characteristic hop, excellent sense of smell, and antibiotics in mother's milk to protect newborns from harm.
A study found a higher prevalence of undiagnosed celiac disease in women with unexplained infertility, which was significantly higher at 5.9%. Dietary changes, specifically a gluten-free diet, improved fertility rates for these women.
Researchers found that microtubules, which act like 'fishing lines,' often incorrectly hook onto chromosomes, resulting in 90% of chromosomes getting connected in the wrong way. This error-prone process can lead to female infertility and miscarriages due to incorrect chromosome separation.
A recent study published by Dietrich Manzey et al. investigated the performance consequences of advanced automated navigation support for surgeons. The results show that navigated-control assistance provides benefits for patient safety and surgical outcome, but also slows performance, increases workload, and reduces situation awareness.
A Kansas State University research team is conducting a three-year study to improve the genetic groundwork for turning sorghum into biofuel. The team aims to increase biomass yield by analyzing sorghum's genetic diversity and developing predictive models to optimize crop improvement.
The study found that boys are maturing physically earlier, while their social and economic roles are becoming more adult. This trend is linked to improved nutrition and disease environments.
Researchers found significant variations in ionization energy along adenine's reaction pathways, challenging previous understanding and implications for spectroscopic measurements.
Researchers at the University of Pennsylvania have developed a color-changing stress sensor using polymersomes and porphyrins, allowing for early detection of system failures. The technology has the potential to monitor drug delivery and track stress in cellular membranes.
Researchers at Virginia Tech and the University of Virginia are creating a portable fall prediction monitoring system that can identify individuals most at risk for falling. The system, called ROOP-Alert, uses sensors to measure gait, posture, and mobility, providing early diagnosis and treatment before falls occur.
TRIAD simplifies biomedical research by aggregating and analyzing rare data, reducing time spent on data translation. The platform is adopted by multiple institutions worldwide, including the National Cancer Institute, for groundbreaking projects like CLL Research Consortium.
A new class of drugs called cardiac myosin activators targets the motor proteins in heart failure patients, prolonging contraction duration and improving blood pumped per stroke. Omecamtiv mercabil shows promise as a safe and effective treatment option with minimal increased energy expenditure.
Researchers found that role abandonment by first responders is unlikely if organizations are proactive in protecting their employees. The study suggests that employers should reach out to families and provide support and resources for spouses to alleviate role strain. Additionally, education on disaster threats and personal protective ...
A national study of 327 patients published in the Journal of Pediatrics found that lung function declines as chest deformity deepens. The more severe the deformity, the more lung function was compromised, primarily due to lung restriction rather than airway obstruction.
Researchers have identified a new protein called Constitutive Differential Growth1 (CDG1) that plays a crucial role in the brassinosteroid-activated pathway. CDG1 adds a phosphate to BSU1, leading to deactivation of BIN2 and promoting gene activity.
Researchers identify the need for a balance between structure and open-ended instruction, and introduce a method to clearly describe classroom instruction. They also advocate for increased use of intelligent tutors like TED to help children design experiments and train them on how to create solid ones.
Researchers at the University of Missouri College of Agriculture have completed two drought simulators designed to mimic real-world conditions. The simulators, measuring 50 feet by 100 feet, will enable in-depth testing under varying environmental conditions and improve food security for farmers.
The Canadian Institutes of Health Research has funded 25 policy-relevant research projects across six provinces to strengthen Canada's healthcare system. These projects will enable meaningful collaborations between researchers and decision makers to address health system challenges.
A new study found that four-year-olds can differentiate between individuals who provide accurate information due to independent knowledge and those who rely on external help. This skill allows children to seek out trustworthy sources, enabling more effective learning.
Researchers found that higher disorder in complex networks accelerates synchronisation, contradicting previous theories. This observation holds true for various real-life networks, including air-transport and social networks.
Researchers used PET scans to measure estrogen-receptor blocking and binding in breast cancer patients. The study found that estrogen-receptor-blocking drugs such as tamoxifen were more effective than aromatase inhibitors in blocking the estrogen receptor in cancer cells.
Researchers developed a method to analyze confiscated indoor fireworks using four techniques, revealing hazardous substances like methanol and boric acid. The technique can be performed with mobile devices and provides conclusive scientific tests on the nature of these liquids.
Researchers at Vanderbilt University have developed a groundbreaking lower-limb prosthetic that enables amputees to walk with a natural gait, thanks to its powered knee and ankle joints. The device has been shown to reduce energy consumption by 30% and enable users to walk 25% faster on level surfaces.
Structural elements in cells organize the motion of receptors, enabling them to receive signals from other parts of the organism. This discovery could have profound implications for drug development and treating diseases like cancer.
A new study published in BMJ Open found no evidence that patients who underwent a heart ultrasound before major surgery had improved survival rates one month or one year after their operation. In fact, some groups of patients may have worse survival rates if they had undergone an echocardiogram.
Researchers discovered B chromosomes causing female-biased sex-ratios in a species of cichlid fish from Lake Victoria. The study also identified multiple protein-coding genes in the B chromosomes, suggesting their role in sex determination.
A two-year NIH-funded study analyzing 83,000 grant applications found a significant 10 percentage point gap in research funding between white and black applicants. Despite accounting for demographic factors, the researchers discovered that applications from black researchers were less likely to be scored and had worse scores.
Biomedical education leaders propose a new model that breaks down silos between disciplines, teaching students to work across fields and study organisms at multiple levels. The new framework includes hands-on training and skills courses to help students tackle fundamental biological questions.
Researchers investigated the muscle-building effect of protein beverages on athletes. Consuming high-quality protein drinks immediately after exercise increased muscle protein synthesis by 33% compared to periodic smaller doses. The essential amino acid leucine plays a crucial role in stimulating muscle growth during recovery.
A team of USDA researchers developed a method to estimate the ethanol potential of switchgrass using near-infrared sensing, which can predict actual and maximum ethanol yields. This technology has the potential to reduce costs by $5 per sample, making it more accessible for bioenergy production.
Research highlights a significant increase in European storm frequency and strength since the late 19th century. However, Martian soil samples show moderate oxidation-reduction potential, suggesting that while oxidizing compounds may be present, life could still thrive.
The first clinical studies of omecamtiv mecarbil suggest it could be a promising treatment for systolic heart failure, improving heart muscle contraction and pumping function. The drug has dose-dependent and concentration-dependent effects on cardiac function, increasing stroke volume, ejection fraction, and fractional shortening.
In Malawi, public radio has become an unlikely platform for ordinary people to air their grievances about abuse and corruption. The Nkhani Zam'maboma programme features contributions by villagers, highlighting local development success stories that often reveal complaints about leaders' behaviour. This approach highlights the complexit...
Researchers at Georgetown University Medical Center have identified a mutant gene STAG2 that is commonly mutated in human cancers and causes aneuploidy, an abnormal number of chromosomes. The study found that 20% of brain, skin, and bone cancer samples lacked the STAG2 protein, leading to increased risk of cancer.
SUNY Downstate researchers found that female animals had higher levels of a specific opioid receptor complex that could explain why certain opioids are more effective in women than men. This discovery suggests new molecular targets for pain management in women, taking into account the stage of their menstrual cycle.
A study by Harvard Medical School found that complex insurance choices in Medicare Advantage plans can lead to poor decisions among elderly patients with low cognitive ability. These patients often benefit from more generous coverage but struggle to navigate the numerous options.
The NIH Blueprint empowers researchers to develop new treatments for neurological disorders, such as vision loss, neurodegenerative disease, and depression. Seven research teams have received funding to explore promising strategies for creating faster and more effective antidepressants.
Species have moved towards the poles at three times the rate previously accepted and to cooler, higher altitudes at twice that rate. On average, species have shifted 12.2m per decade in elevation and 17.6km per decade in latitude.
Researchers will analyze tumor samples from 100 patients with large intestine cancer or chronic lymphatic leukemia before and after drug treatment. The goal is to identify genetic mutations that contribute to treatment resistance, enabling the development of more effective cancer therapies.
A team of researchers has found that Greenland's Mittivakkat Glacier is melting at an unprecedented rate, with two consecutive record losses in mass observations for 2010 and 2011. The findings suggest that the glacier's mass balance has been negatively affected by higher surface temperatures and low precipitation.
Women in urban Ecuador turn to direct sales as an alternative to low-paying jobs due to gender discrimination and caregiving responsibilities. Adjustable hours and demand for products make it a viable option.
Researchers at Mount Sinai School of Medicine will identify genetic markers for each patient enrolled in the study, inputting them into electronic medical records for tailored treatment. The study aims to improve management of heart disease risk factors and prevent onset.
Valley Presbyterian Hospital will receive a $500,000 grant to implement policies and procedures promoting exclusive breastfeeding among new mothers. The three-year initiative aims to enhance the hospital's ability to provide intensive training, new procedures, and postnatal support to encourage more mothers to rely on breast milk.
The U.S. Department of Energy's national laboratories enabled the discovery of a groundbreaking new drug treatment for malignant melanoma, with FDA-approved drug Zelboraf (vemurafenib) showing great promise in disrupting disease progression.
Researchers at Oregon State University have developed a new system that combines computer vision, machine learning, and automated planning to improve operations in various industries. The system is based on analyzing football plays and can be applied to tasks such as factory efficiency, airport operation, and nursing care.
Researchers at the Broad Institute and Whitehead Institute found that cancer cells can interconvert between different types, existing in phenotypic 'states' that can change over time. This decentralized model challenges the traditional view of cancer stem cells as a hierarchical society.
A study published in Journal of Neurotrauma found that over 70% of patients with traumatic brain injury reported headaches during the first year after their injury. Females and individuals with a pre-injury history of headache were significantly more likely to experience post-injury headaches.
A new study from Tel Aviv University finds that LGB soldiers in the US military experience high levels of verbal, physical, and sexual abuse despite official support. The researcher suggests that mandatory sensitivity training is essential to address this issue and create a more inclusive environment.
Researchers identified three periods of evolutionary innovation in gene regulation that increased in frequency during different periods in vertebrate evolution. These innovations affected genes involved in embryonic development, cell-to-cell communication, and signaling pathways.
The research found that elongated particles behave differently due to surface tension, leading to a uniform coating. The discovery could translate into new formulations for product coatings or better inks and paints.
Research suggests that statin cholesterol-lowering medications can lower stroke risk in patients with ischemic strokes. However, patients with hemorrhagic strokes or certain high-risk profiles may not benefit from statins. Further research is needed to understand the optimal use of statins in these cases.
Patients with clinically diagnosed superficial vein thrombosis are four to six times more likely to develop venous thromboembolism, a dangerous and often life-threatening condition. Studies have shown that patients with
A study published in PLOS ONE found that pharmaceutical advertisements in biomedical journals are often non-compliant with FDA guidelines, failing to provide critical safety and efficacy information. The study's findings highlight the need for improved regulation of pharmaceutical marketing.
The University of Tennessee, Knoxville, has been awarded a five-year, $18 million grant to lead the development of ultra-wide-area resilient electric energy transmission networks. The center aims to create a smart grid system that operates efficiently and reliably over long distances.
Research found that embryos exposed to high levels of saturated fatty acids have fewer cells, altered gene expression, and impaired metabolic activity. This study suggests a link between maternal obesity and diabetes and reduced fertility, highlighting the importance of pre-pregnancy health for successful conception.