Researchers have developed super-mini vehicles that can carry drugs and imaging agents into the body, revolutionizing medicine by improving drug solubility and bio-distribution. The devices use self-assembling nano-sized structures to cross membrane barriers and enable combination therapies.
UT Southwestern Medical Center researchers have found that blocking two specific RNA molecules can suppress abnormal blood vessel growth in degenerative eye disorders. This finding suggests a potential strategy to treat age-related macular degeneration, a leading cause of blindness among older people.
Researchers found that cash-based overcompensation leads to higher satisfaction ratings than industry-standard compensation or voucher-based overcompensation. Participants were most satisfied with a $400 cash bonus, but satisfaction levels did not increase linearly with the amount of cash provided.
A nursing expert emphasizes the importance of preventing maternal-child health disparities by recognizing signs of domestic violence in healthcare settings. Health care providers require training to effectively connect victims with resources and support services.
Researchers at University of Pennsylvania School of Medicine found that disrupting the circadian rhythms of fruit flies by feeding them at incorrect times led to reduced fertility. The study suggests a connection between diet and reproduction, highlighting the importance of timing in maintaining reproductive capacity.
The US construction industry has the highest number of traumatic brain injuries (TBI), with a fatality rate of 0.8 per 100,000 workers per year. Falls are the leading cause of fatal TBI, accounting for 29% of all fatalities.
The team is studying 14 locations along the Passaic River to determine the effect of combined sewer overflows on water quality. They are also analyzing samples for bacteria in dry and wet weather events to understand pollution patterns.
Research recommends considering dried fruits equivalent to fresh fruits in dietary guidelines, highlighting their comparable fiber and potassium content. Dried fruits also contain bioactive compounds with potential health benefits, including anti-cancer properties.
Researchers tracked 27 unique viruses affecting honey bees, including four unknown strains and six species of bacteria and fungi. The study provides a baseline measurement of pathogens in healthy hives, shedding light on the causes of colony collapse.
A new study suggests that widespread urban development can lead to reduced nighttime winds and increased air pollution in coastal cities. Researchers found that paved surfaces absorb heat, reducing the temperature contrast between land and sea, and causing stagnation. This can result in a buildup of pollutants during warm summer weather.
A virtual issue explores the long-term environmental impact of the Chernobyl disaster and its relevance to future nuclear accidents. Research reveals radiation can affect entire ecosystems, highlighting the need for better understanding and mitigation strategies.
A new collaborative research center aims to study the diversity of Arabic manuscripts from a historical and comparative perspective. The project, led by Prof. Dr. Tilman Seidensticker, will analyze nine layout characteristics to understand their functions in everyday transcriptions.
A native species, the plucky winter ant, has been discovered using chemical warfare to combat the Argentine ant invasion. In laboratory testing, the poison had a 79 percent kill rate, making it a potential game-changer in ecosystem defense.
A new FRET-based sensor has been developed for real-time imaging of intracellular redox dynamics, allowing for the quantification of redox state. The sensor's dynamic range is improved, enabling better discrimination between redox states in complex biological specimens.
Hanadi Rifai will test parts of Galveston Bay for dioxins and PCBs to identify the source of pollutants and determine concentrations in marine life. Her findings will help state officials develop effective management strategies, including bioremediation and commercial fishing bans.
A Spanish investigation reveals that glaciation's impact on dung beetle distribution persists in Europe. The analysis shows two distinct patterns of species presence in the north and south, influenced by past and present climates.
Research finds that paved surfaces in cities like Houston can lead to stagnant air and increased pollution by altering wind patterns. By adding parks and lakes, cities may be able to improve air quality by blowing away pollutants.
A study found that infection with influenza likely increases the incidence of invasive pneumococcal disease (IPD). Influenza infection may increase the short-term risk of bacterial invasion in individuals already colonized with Streptococcus pneumoniae, which causes IPD. This suggests that some cases of IPD could be attributable to inf...
Research suggests that UK government plans to divert mentally ill prisoners into mental health services are unlikely to succeed due to a lack of suitable facilities. The study found that only a small percentage of psychotic prisoners receive treatment, and those who do often face significant barriers to follow-up care after release.
A University of Cincinnati researcher is using simulation modeling to study the impact of electronic health record implementation on emergency departments. The study aims to quantify the operational disruption caused by EHRs and optimize efficiency during implementation.
A new study finds that pregnant women who gain too much weight are more likely to have newborns with high body fat, regardless of pre-pregnancy weight. This increased obesity risk exists even when birth weight is normal and may be associated with higher childhood obesity rates.
Researchers have discovered that dolphins can generate two sound beam projections simultaneously, each with different frequencies and directions. This ability could help dolphins locate objects more accurately, according to Dr. Josefin Starkhammar, who led the study published in Biology Letters.
A Finnish twin study found that obese individuals have higher amounts of polyunsaturated fatty acids in their adipose tissues than non-obese twins. The researchers suggest that this adaptation helps preserve membrane function as the cells expand, but breaks down in morbidly obese individuals.
A study by Rosalia C. M. Simmen found that blueberry powder improved indicators of rat mammary gland health, including branching and biochemical markers like PTEN. The effects have not been shown in humans and may aid breast cancer research.
Researchers have discovered that GPS stations can detect the impact of underground nuclear tests on the ionosphere, allowing for the confirmation of clandestine nuclear explosions. By analyzing changes in atmospheric electron density, scientists can pinpoint the location and timing of such events.
Researchers found that people's brains become distracted by previously associated rewarding objects, such as money, even when they're not important in the task. This effect persists for weeks and is linked to impulsivity levels.
A new study reveals that bacteria living in mosses on tree branches contribute to nutrient dynamics, sustaining the long-term productivity of coastal temperate rainforests. Large, ancient trees provide habitat for mosses and cyanobacteria, which fix nitrogen and fertilize the forest.
A recent study found that women veterans of US wars in Iraq and Afghanistan experienced similar levels of combat-related stress and post-deployment mental health impacts as their male counterparts. The research, based on survey responses from 595 service members, suggests that women's exposure to combat stress may be only slightly lowe...
Patients undergoing elective total hip or knee arthroplasty at hospitals with lower surgical volume had a higher risk of venous thromboembolism and mortality following the procedure. Researchers found that hospital procedures and peri- and post-operative care processes may contribute to complications.
Developing better modeling techniques for protein folding is vital to creating effective pharmaceutical treatments for diseases such as Alzheimer's and Parkinson's. The new algorithm can predict protein folding in 10 minutes on a laptop, improving upon classical methods that required hundreds of thousands of CPU hours.
A clinical trial at Michigan State University is testing the effectiveness of acetazolamide in reducing vision loss in patients with idiopathic intracranial hypertension (IIH). The study aims to establish evidence-based treatment strategies and follow patients for up to four years to observe long-term treatment outcomes.
The Collage Authoring Environment won first prize for its scalable architecture designed to support authors, reviewers, and end users as well as publishers. SHARE: A Web Portal for Creating and Sharing Executable Research Papers took second place, while A Universal Identifier for Computational Results received third prize.
A new report examines the ways to protect sex workers, highlighting the need for decriminalization and policy changes. The study, conducted by Concordia University and University of Windsor researchers, reveals that sex work is increasingly dangerous and unprotected, with many sex workers facing marginalization and violence.
The UK Ocean Acidification research programme aims to study the impact of changing CO2 levels on marine organisms and ecosystems. The cruise will conduct experiments using tanks of natural seawater collected from the sea, subjecting them to various levels of carbon dioxide that may occur in the future.
A new study found that coffee consumption improved treatment response in advanced patients with chronic liver disease and hepatitis C. Patients who drank three or more cups of coffee per day were two times more likely to respond to treatment, with higher rates of early virologic response and sustained virologic response.
A new study published by The Endocrine Society finds that testosterone levels do not decline with age in healthy older men. In fact, serum testosterone levels remained stable across the board, indicating that age is not a contributing factor to declining testosterone levels.
A recent study reveals that charities in England receive significant public funding, with 70% of organisations working with socially excluded or vulnerable people relying on government support. The study also highlights regional variations and uneven distribution of public funding across the sector.
A Clemson University research team, led by Juan Gilbert, has been awarded a $4.5 million grant to create an accessible voting technology system. The Prime III software allows voters to cast ballots by touch or voice, and includes advances in four areas: accessibility, simplicity, verification, and administration.
The open-source software, GenPlay, is designed to help biologists visualize, analyze and transform raw genomic data. Biologists can now analyze their own data using a user-friendly tool that provides continuous visual feedback, making it easier to make sense of the avalanche of new data.
A study introduced at SNM's 58th Annual Meeting found that 4D PET imaging using state-of-the-art image reconstruction and motion correction significantly improves cancer detection. This method provides clearer images, especially for small lesions, allowing for more accurate diagnosis and better treatment planning.
Puyehue-Cordón Volcano in Chile erupted on June 4, prompting 3,500 evacuations. NASA's Terra Satellite, GOES-13, and GOES-11 captured images of the massive ash plume blowing northeast and southeast across the Atlantic Ocean.
Researchers at North Carolina State University have developed a method to apply conductive nanocoatings to textiles, enabling the creation of flexible electronic devices. The new technique uses atomic layer deposition and measures conductivity using larger probes, providing a better understanding of how to apply coatings on textiles.
A large study found that carrying the FVL gene variant substantially increases the risk of colorectal cancer, with a six-fold increase in risk compared to those without the variant. Another gene variant of clotting factor XIII was also associated with a 15% lower risk of bowel cancer.
A recent study by Fred Hutchinson Cancer Center found that bankruptcy rates among cancer patients rise fourfold within five years of diagnosis. The risk is highest for lung, thyroid and leukemia/lymphoma cancer patients, who face significant financial stress due to income loss and treatment costs.
Researchers have clarified an important step in the complex control circuit of insulin in the brain. Insulin inhibits nerve impulses, suppressing feelings of satiety and increasing energy expenditure, promoting overweight and obesity.
Researchers use molecular imaging to gauge heart efficiency in subjects with a pathogenic mutation linked to HCM. They find carriers of the mutation already have less efficient hearts despite the absence of any symptoms. Alcohol septal ablation is shown to be an effective treatment for symptomatic patients who remain symptomatic despit...
A new study found that overweight girls who consumed sugar-free, low-fat desserts several times a week lost more weight and had better blood pressure control compared to those who ate dessert once a week. The low-glycemic index desserts also improved appetite-suppressing hormone levels and insulin resistance markers.
Researchers found that myeloid-derived suppressor cells mediate immune suppression during pregnancy, allowing tumors to spread more easily. This mechanism may also be relevant to lung cancer patients with poor prognosis.
The Endocrine Society released a clinical practice guideline recommending vitamin D screening and dietary intakes for children and adults at risk of deficiency. Key findings include recommended daily intake ranges, from 400 IU/day for infants and 600 IU/day for adults, to prevent vitamin D deficiency.
Researchers developed a novel form of radioimmunotherapy that targets antigens associated with renal cell carcinoma. Patients receiving up to three doses show dramatic slowing of cancer growth and stabilization of their disease. The therapy, Lu-177-cG250, targets kidney tumors with high effectiveness for reducing cancer proliferation.
Researchers develop a new therapy to prime tumors before radiotherapy, reducing damage to healthy tissue. The treatment shows effective targeting of tumors with minimal side effects.
Researchers found that people with Parkinson's disease are twice as likely to develop melanoma, a deadly form of skin cancer. Women with Parkinson's disease are also at higher risk, particularly for aggressive forms of the disease.
The study presents promising results for the clinical use of a new integrated PET/MRI system, which provides diagnostic information on soft tissues and physiological functions. The technology has been shown to be comparable in detecting cancerous tumors as conventional PET/CT methods.
Researchers found that syntax rules, which govern word order in language, also apply to mathematical equations and may be universally applicable. The study used structural priming, a cognitive process where past structures influence future ones, to demonstrate this connection.
A recent brain imaging study suggests that men with a history of violent behavior may have greater gray matter volume in certain brain areas, whereas those with substance use disorders may have reduced volume in other areas. The study found associations between increased gray matter volume and higher scores for psychopathy and lifelong...
Researchers have found a link between methane production and levels of archaeol in the faeces of cows, sheep, and deer, offering a potential solution to quantify animal methane contributions. The discovery could enable more accurate assessments of global greenhouse gas emissions.
Researchers at Queen Mary University of London found that relocating Met molecules from the inside to the cell surface could halt cancer growth and shrink tumours. This approach may lead to new drugs for treating aggressive breast and lung cancers.
Researchers used molecular imaging to visualize changes in the brains of heavy marijuana smokers versus non-smokers, finding a decreased number of cannabinoid CB1 receptors. Chronic cannabis smoking caused downregulation of these receptors, but they returned to normal when subjects stopped smoking.
A nationwide study found that young adults aged 18-27 experience increased self-esteem and mastery when holding credit card and education debt. The effect is strongest among those in lower economic classes, who see debt as a resource for achieving goals and feeling in control of their lives.
A study published in Archives of Pediatrics & Adolescent Medicine found that adolescent girls who followed a DASH-style diet had smaller gains in overall body mass index (BMI) over 10 years compared to those on other diets. Higher consumption of fruits, whole grains, and low-fat dairy products was associated with less weight gain.