A new genomic test has shown promise as a predictor of chemotherapy response and survival benefit in women with invasive breast cancer. The test combines multiple signatures, including estrogen receptor status, endocrine therapy response, chemotherapy resistance and sensitivity, to predict treatment outcomes.
A Cochrane Systematic Review revises conclusions on two fertility treatments, finding GnRH antagonists comparable to agonists in live birth rates while reducing ovarian hyperstimulation syndrome risks. This shift justifies the use of GnRH antagonists over agonists.
Research at DDW 2011 shows that patients taking clopidogrel after polyp removal have a relatively low risk of bleeding. Teduglutide increases intestinal absorption, decreasing dependence on intravenous fluid in those with short bowel syndrome. Rifaximin reduces death rates in advanced liver cirrhosis and ascites patients.
Researchers found that Lactobacillus rhamnosus promotes healing of the intestinal lining in mice by inducing reactive oxygen species. This discovery could guide doctors to improved treatments for intestinal diseases.
A new study found that systemic sclerosis is an independent determinant for moderate to severe coronary calcification or atherosclerosis in patients. The research team discovered that 57% of patients with systemic sclerosis had high coronary calcification scores, compared to 29% of healthy controls.
Researchers find increased MAN2C1 levels enhance prostate cancer recurrence and metastasis, highlighting a potential target for blocking tumor progression. The study could lead to the development of new treatments for patients with advanced prostate cancer.
A Cochrane Systematic Review of randomized controlled clinical trials found no protective effect against non-melanoma skin cancer and prostate cancer. Researchers also noted potential toxic effects from long-term selenium intake.
Researchers used a linguistic analysis tool to study 9/11 pager messages, finding that anger was not as widespread as initially thought. In reality, people expressed feelings of sadness, fear, and a desire for connection during the tragedy.
Researchers at Wayne State University have found a new method to identify children with major depressive disorder (MDD), setting them apart from both healthy children and those with obsessive compulsive disorder (OCD). Cortical thickness in the brain was used as a key factor, revealing distinct differences between MDD patients and heal...
A recent report from the University of Southampton found widespread acceptance of nurse and pharmacist prescribing among patients, with safe and appropriate practices reported. The study highlights the growing contribution of these healthcare professionals to patient care, particularly in primary care settings.
Researchers have discovered that pyrite nanoparticles from hydrothermal vents are a significant source of iron for ocean life, with the ability to travel long distances and form a potentially important food source. These nanoparticles are dispersed into the ocean rather than falling to the bottom due to their small size.
A global health agreement is necessary to clarify national and global responsibilities for health and close major health inequities, say researchers from Georgetown University. The Joint Action and Learning Initiative on National and Global Responsibilities for Health aims to create a political space for such an agreement.
Researchers have developed a new technique to improve artificial photosynthesis by using cuprous oxide coated with a thin film of atoms, enabling the production of hydrogen from water. The process utilizes widely available materials and can be easily scaled up for industrial fabrication.
Children whose mothers are successfully treated for depression show progressive improvement in their own behaviors even a year after treatment discontinuation. The faster mothers get better, the faster and greater their children's improvements are.
Researchers at Oregon State University have experimentally confirmed the presence of the rotational Doppler effect in individual molecules for the first time. The finding has implications for understanding molecular spectroscopy and high-energy electron studies.
Researchers found that Irritable Bowel Syndrome is linked to an overgrowth of bacteria in the gut, as well as a connection to food poisoning. The study suggests that military personnel are at a higher risk for developing IBS due to their increased exposure to gastroenteritis.
Scientists investigate how a virus affecting the Indian meal moth impacts its host populations in size, with potential to inform better pest management strategies. The research could lead to improved techniques for controlling invasive species and pests.
Research published by the American Psychological Association found that people with good peer support systems at work may live longer than those without. The study also showed that control and decision authority had a different effect on mortality rates for men and women.
A new antibody called 5750 has been developed by researchers at Ruhr-University Bochum to label specific stem cells in the nervous system. The antibody targets a sugar residue on the cell surface called LewisX, which is found on different types of neural stem cells.
Research reveals that long non-coding RNA SPRY4-IT1 promotes cellular survival and invasion in melanoma cells, suggesting its potential as an early biomarker. The study also found reduced levels of another non-coding RNA, miR-211, in melanoma cells.
Dr. Elizabeth Hausler receives award for sustainable reconstruction in developing countries, improving lives of millions through culturally accepted and economically viable buildings.
Researchers identified previously undiscovered high-risk genetic features in T-cell acute lymphocytic leukemia (T-ALL) using zebrafish models. These genetic characteristics can predict which patients are more likely to experience aggressive forms of the disease that recur after treatment or do not respond to therapy.
A recent study at Nationwide Children's Hospital identified 11 patients with Self-Embedding Behavior (SEB), a form of self-injurious behavior involving foreign objects in soft tissue. The majority of patients had psychiatric disorders, histories of out-of-home placements, and suicidal ideations.
A study by researchers at Virginia Commonwealth University finds that deaf animals' brains reorganize sensory inputs to preserve their behavioral functions. The research provides insight into brain reorganization following sensory loss, potentially informing the development of more effective rehabilitative medicine for deaf patients.
Scientists have discovered an exotic nucleus called fluorine-14, comprising nine protons and five neutrons, which exists for a fraction of a second before releasing a proton. The team's experiments were enabled by supercomputers and advanced simulation codes, including the Universal Nuclear Energy Density Functional (UNEDF) project.
Ostracism can lead to extended periods of pain and negative experiences due to its impact on human needs like belonging and self-esteem. The pain caused by social exclusion can linger for a long time if coping mechanisms are not effective, leading to depression, alienation, and feelings of unworthiness.
Ingo Schlupp, OU Department of Zoology associate professor, receives top award for evolutionary biology and animal behavior research. He will spend a year at University of Potsdam in Germany working on genomics of the Amazon molly.
Purdue University researchers introduce a new class of software called surrogate interaction, enabling designers to easily change complex object features. This approach also enhances video game experiences by allowing players to manipulate animated characters and objects simultaneously.
The Brazilian health system has expanded health care coverage, improved population health, and reduced inequalities, yet universal and equitable coverage remains elusive. Constraints on health care financing, infrastructure, and human resources hinder the goal of universal access.
A Spanish-Mexican research team found that wild birds exhibit ageing in terms of reproductive capacity and DNA damage. As males age, their germline becomes damaged, increasing the risk of genetic illnesses in their offspring.
Researchers at UC San Diego and Scripps Institute of Oceanography used matrix-assisted laser desorption ionization mass spectrometry to reveal multiplex microbial interactions. The technique allowed them to see competition for resources, secretion of molecules altering neighboring organisms' phenotypes.
Researchers discovered that married couples tend to select partners based on their social and political attitudes rather than physical traits or personality. This finding suggests that people place more emphasis on finding a kindred spirit for politics, religion, and social activities.
A3309, a new medication, targets bile acid recycling to promote bowel movements and relieve constipation symptoms. In a Phase II study, patients with constipation reported significantly less straining and softer stool after taking A3309.
A new study by Henry Ford Health shows that patients with mild hearing loss are motivated to purchase hearing aids based on factors other than cost, including perception of need and insurance coverage. Despite significant advancements in hearing aid technology and comfort, many adults with mild hearing loss do not acquire devices.
A new study reveals that American married couples often choose partners with similar political views, resulting in a strong political bond from the early years of marriage. This 'sorting' behavior may contribute to polarization and reinforce ideological divisions within families.
A new study at Columbia Presbyterian Medical Center reveals high rates of chronic hepatitis B infection among pregnant minority and immigrant women in NYC, with many not receiving standard care. The study highlights the importance of targeted screening and education for this vulnerable population.
A study in Michigan's Upper Peninsula reveals that deer are outcompeting saplings for resources, hindering regeneration of sugar maple trees. The research suggests a trade-off between deer populations and timber harvesting, with areas in the south facing severe sapling shortages.
The USDA has developed a cutting-edge optical scanning system that uses two different kinds of lighting and a sophisticated camera to inspect fresh produce items. The system can detect defects and contaminants, such as cuts, bruises, and specks of fertilizer, in a single image.
A study by Asita De Silva and colleagues found that low-dose adrenaline given before antivenom treatment significantly reduces acute severe reactions in snakebite patients. This finding highlights the importance of improving antivenom quality in countries where snakebites are common.
A study found that erythropoietin use in heart attack patients after PCI did not reduce infarct size and was associated with higher rates of adverse cardiovascular events. The REVEAL trial evaluated the safety and effect on infarct size of a single intravenous dose of recombinant human erythropoietin.
Research at DDW 2011 reveals colonoscopy is effective in preventing and detecting colorectal cancer, but disparities persist among lower socioeconomic groups. Ambulatory surgical centers provide safe alternatives to hospitals for screening colonoscopies, while the administration method may impact patient outcomes.
A new study published in Respirology reveals that adult patients with pneumonia who have vitamin D deficiency are more likely to die within the first 30 days after hospital admission. The researchers found no explanation for the association beyond patient age and other factors.
A recent study published in Breast Cancer Research found that coffee consumption is associated with a lower incidence of ER-negative breast cancer. The research, which adjusted for other lifestyle factors, suggests that moderate coffee consumption may offer protective effects against this type of breast cancer.
A new study from the University of Utah found that mothers of twins tend to be healthier and live longer than singleton mothers, with stronger women being more likely to naturally conceive twins. The research analyzed data from over 58,000 Utah women born between 1807 and 1899, revealing a link between twin birth and longevity.
The Cephalalgia Award has been won by A Stankewitz and colleagues for their groundbreaking paper on a new trigemino-nociceptive stimulation model for event-related fMRI. The study offers high spatial resolution and potential to advance headache science.
Researchers have identified genetic mutations that predict risk of sudden cardiac death and cardiac events in patients with Long QT syndrome. The findings could lead to personalized treatment approaches for individuals with the condition, who are often at risk but may not exhibit typical clinical symptoms.
Researchers found that glaucoma is more likely to progress with peak intraocular pressure of 18 mm Hg or higher, as well as cornea thinning and disc hemorrhage. These risk factors can help clinicians decide how aggressively to treat patients to slow glaucoma progression.
Researchers have discovered an evolutionary change 65 million years ago that may have set the pace for present-day flowering plants' rapid growth rate. The team measured vein densities in ancient leaves to determine when modern vegetation first appeared.
A £5M funding call aims to extract valuable chemicals from grain brewing co-products, enhancing the UK's biorefining industry and reducing reliance on fossil fuels. Researchers will focus on overcoming bottlenecks and developing new methods for increasing product value.
A new study of U.S. veterans ages 70 and older found that healthy seniors benefit most from current colon cancer screening methods, while less healthy veterans may experience a net burden. The study highlights the need to target screening for those who are likely to benefit and re-evaluate screening for those who are not.
Researchers have discovered a new compound, VUAA1, that directly stimulates the Orco co-receptor in mosquito odorant receptors, overwhelming the insect's sense of smell. The compound is thousands times more effective than DEET and works against flies, moths, ants, and other insects.
Approximately 14% of all strokes occur during sleep, preventing patients from receiving timely clot-busting treatment. Researchers estimate that around 58,000 people in the US go to the emergency department with a wake-up stroke each year.
A comprehensive study of 55,000 children in South Korea found that over two-thirds of Autism Spectrum Disorder cases were unrecognized and untreated. The research suggests that autism prevalence may be higher than previously thought, particularly in non-clinical populations.
According to a recent report, dementia and mild cognitive impairment are prevalent among 'oldest old' women, who are 85 years of age and older. The prevalence of these conditions increases with age, with the highest rates found in women over 90 years old.
Control of infectious diseases such as cholera, diarrhoea, Chagas disease, and those preventable by vaccination have been successful in Brazil. However, failures exist, including the ongoing public health problem of dengue fever and visceral leishmaniasis.
Three Ontario projects focused on biomonitoring, gene function, and synthetic antibody production will further knowledge and discovery in these fields. The funding will support the creation of new methods to monitor environmental change and improve treatment options for cancers.
A new Weill Cornell study found that teenagers who drink alcohol tend to spend more hours using computers for non-school-related activities. The survey of 264 teenagers also linked drinking to more frequent social networking and listening to music, but not to video games or online shopping.
Lubchenko investigates phase-change materials for ultra-fast computer memory and protein aggregation, potentially treating diseases like Alzheimer's. His work earns him prestigious Alfred P. Sloan Research Fellowship.
A new study from the Bradley Hasbro Children's Research Center suggests that teens who are offered free or low-cost rapid HIV testing are often willing to accept the test. The study found that 53% of teens in the age group accepted the test, with African-American teens more likely to agree.
A recent study at UCSD found that NOTES sleeve gastrectomy was effective and safe for morbidly obese patients, with no reported complications. The procedure eliminated the need for a large incision, resulting in shorter hospital stays.