Researchers have developed an artificial plasmid coding for Sindbis virus replicase genes that causes regression of lung and melanoma tumors in mice. The plasmid forces cells to produce double-stranded RNA, leading to cell death and activation of immune responses.
Scientists have developed stronger, lighter, and more sustainable automotive plastics by harnessing the power of plant-based nano-cellulose fibers. These innovative materials are set to revolutionize car production, reducing weight and improving fuel efficiency.
A new study published in Nature suggests that biodiversity can evolve in complex environments where previously thought to be impossible. Researchers found that both 'fit' and 'unfit' species can coexist indefinitely due to trade-offs between growth rate and efficiency.
Dr. Yosef Shiloh is recognized for his groundbreaking work on ataxia-telangiectasia (A-T), a rare disease caused by a defect in the cellular response to DNA damage. His identification of the ATM gene has revolutionized the field, leading to significant advances in our understanding of DNA damage response and repair.
The American Association for Cancer Research (AACR) has recognized 24 new grant recipients for their groundbreaking research in cancer treatment and prevention. These grants support innovative projects focused on invasive bladder cancer, ovarian cancer, skin tumorigenesis, tumor microenvironment, head and neck cancer radiation response...
The American Association for Cancer Research (AACR) has awarded 27 undergraduate students with the AACR-Thomas J. Bardos Science Education Award, recognizing their dedication to advancing cancer research. The award aims to inspire science students at the undergraduate level to pursue careers in cancer research.
The Arctic Ocean's freshwater content has risen significantly, with a 20% increase since the 1990s. This change affects global ocean circulation and heat exchange between the ocean and atmosphere. Researchers analyzed over 5,000 salt concentration profiles to determine this increase.
Baylor University researchers have discovered the oldest archaeological evidence of human occupation in the Americas at a Central Texas site. The findings, published in the journal Science, date the peopling of the Americas to around 15,500 years ago, contradicting previous estimates of 13,000 years.
The Pancreatic Cancer Action Network and AACR have awarded Jennifer M. Bailey and E. Scott Seeley $600,000 grants to pursue groundbreaking research on pancreatic cancer initiation and progression. Their projects focus on novel insights into KRAS mutations and transport proteins as modifiers of oncogenic signaling.
The American Association for Cancer Research has awarded 50 Minority Scholar in Cancer Research Awards to early-career scientists from diverse backgrounds. The recipients, who were chosen based on their qualifications and potential impact, will receive funding and support to attend the annual meeting and present their research.
The American Association for Cancer Research has awarded grants to researchers studying carcinoid tumors and pancreatic neuroendocrine tumors. These grants will support the development of new treatments and therapies for these cancers, including those targeting the menin-regulated signaling pathway and oncolytic viral therapy.
A research team at the University of Colorado Cancer Center has identified a new enzyme biomarker, ALDH1B1, present in nearly all colon cancer cells, which could help physicians diagnose colon cancer earlier and treat it more effectively.
Pier Paolo Pandolfi has made significant contributions to cancer research, particularly in the area of leukemia treatment. His work on mouse models and chromosomal translocations has led to the development of novel therapeutic strategies, making APL a curable disease.
Shannon Fortin, a University of Arizona graduate student at TGen, has been awarded the $7,000 Achievement Rewards for College Scientists scholarship. This award will enable her to pursue two simultaneous post-graduate degrees while continuing her research on glioblastoma multiforme, the most malignant form of brain cancer.
Peter Shizgal, a leading researcher in reward, motivation, and decision-making, has been awarded the prestigious Prix Adrien Pinard. A prolific scientist, he is known for his work on cognitive, emotional, and neural mechanisms that underlie human behavior.
A new study predicts significant changes in arable land globally and regionally due to climate change. Regions like China, Russia, and the US are expected to see an increase in farmland area, while Africa, Europe, India, and South America may lose land.
Researchers at MIT have devised a new method to detect internal damage in airplane composite materials, allowing for faster inspection. The approach uses a handheld device and heat-sensitive camera to reveal underlying problems.
The Pancreatic Cancer Action Network and the American Association for Cancer Research awarded 10 grants totaling nearly $3 million to support innovative pancreatic cancer research. The recipients will be honored at the AACR Annual Meeting, with a focus on building a comprehensive and coordinated pancreatic cancer research community.
A study published in American Journal of Respiratory and Critical Care Medicine found that a written action plan attached to the drug prescription improves asthma control in preschool-aged children. The provision of the plan significantly improved patient adherence to prescribed medications and physicians' recommendations.
Carey Anders will receive a $181,000 grant to test the effectiveness of PARP-inhibitors and nanoparticle agents in treating triple-negative breast cancer brain metastases. The research aims to improve survival rates for women with this aggressive form of breast cancer.
Theodore W. Gray, a best-selling author and science writer, has won the American Chemical Society's James T. Grady-James H. Stack Award for his work in interpreting chemistry for the public. The award recognizes Gray's ability to make complex chemical concepts accessible to a broad audience through his writing and visual displays.
A two-year energy audit by McMaster University identified significant energy conservation measures that could save Hamilton schools almost $2.4 million annually. The audit found opportunities to install advanced heat recovery systems, boilers, solar, and wind generating systems.
Researchers found that individuals with a better understanding of their friends' personality triggers had stronger, less conflict-ridden relationships. This knowledge was crucial for navigating social situations and avoiding frustration in friendships.
Susan Band Horwitz, a renowned molecular pharmacologist, receives the Eighth Annual AACR Award for Lifetime Achievement in Cancer Research. Her pioneering work on paclitaxel has led to significant advancements in cancer treatment, particularly in ovarian, breast, and lung carcinomas.
A team of researchers at Marshall University has identified and analyzed unique adult animal stem cells that can transform into neurons, which could pave the way for novel therapies for slowly progressing diseases like Parkinson's and multiple sclerosis. The discovery is especially interesting as it involves using readily available and...
A new RAND Corporation study found that high-deductible health plans reduce healthcare spending, but also lead to cuts in preventive care such as childhood vaccinations and cancer screenings. Costs only decrease significantly when deductibles reach $1,000 per person.
Researchers at the University of Colorado School of Medicine found that people living at high altitudes have a lower chance of dying from ischemic heart disease and tend to live longer than others. Lower oxygen levels may spur genes to create blood vessels, reducing the risk of heart disease deaths.
A new study published in Epilepsia found that children with epilepsy are at increased risk of developing behavioral and psychiatric problems. The study showed that girls were more likely to experience emotional problems, while boys had more hyperactivity/inattention issues and peer relationship problems.
Scientists have discovered that smells are processed by the olfactory bulb and cortex through a dialogue of rapidly firing nerve cells. This new understanding expands our knowledge of the complex process of smell detection and how it filters and categorizes odors.
A 40th anniversary Corvette was sold at a Barrett-Jackson auction to benefit the TGen Cancer Research Fund, named after Jackson family members who died from colon cancer. The sale raised over $250,000 for the fund, with all proceeds going towards life-changing research.
A new study finds that biodiversity can be conserved while resources are used to support local household livelihoods, especially when managed under systems that involve local forest users. The research suggests formalizing the rights of local people to contribute to forest management and governance can promote dual success.
Researchers have discovered that smaller quantum dots can increase the efficiency of solar panels by generating multiple excitons from a single photon of light. This breakthrough has significant implications for commercial realizations of multiple-exciton generation (MEG) technology.
A new study published in the Journal of the American Dietetic Association found that inadequate nutrition is a significant risk factor for anemia in postmenopausal women. The study, which analyzed data from over 72,000 women, found that deficiencies in multiple nutrients were associated with a higher risk of persistent anemia.
The American Association for Cancer Research and the Landon Foundation will present three INNOVATOR Awards to recognize emerging mid-career researchers. The awards support innovation in cancer prevention, international collaboration, and personalized medicine research.
A new statistical model helps regulators identify ships carrying unwanted species, enabling more effective screening of ballast water. The model's findings are published in Environmental Science & Technology, providing a promising solution to prevent bioinvaders from causing environmental damage.
The FDA is considering new rules to speed up confirmatory trials of drugs granted accelerated approval, following a review that found six indications remained on the market without confirmation. The median time between accelerated and regular approval was 3.9 years, with some drugs remaining on the market for over 10 years.
The American Association for Cancer Research (AACR) recognizes leaders in the minority cancer community with the Minority-Serving Institution Faculty Scholars in Cancer Research Awards. The awards aim to increase scientific knowledge, encourage research, and inspire students to pursue careers in cancer research.
Researchers found that Zileuton, an asthma drug, reduced gamma secretase's production of amyloid beta and subsequent plaque buildup in the brain by over 50% in a transgenic mouse model. This breakthrough suggests potential for new Alzheimer's treatment using an FDA-approved medication.
A University of Georgia study found a supervised, low-to-moderate intensity weight-lifting exercise program to be safe and beneficial for pregnant women. The research showed that participants increased their strength without experiencing musculoskeletal injuries or significant changes in blood pressure.
A team of international researchers from Fred Hutchinson Cancer Research Center and University of Washington have made significant contributions to understanding human papillomavirus (HPV) infections. They developed the HPV vaccine, which has the potential to prevent over half a million HPV-associated cancers worldwide.
Dr. Arthur D. Levinson is recognized for his leadership and extraordinary achievements in cancer research, leading to targeted drugs and personalized healthcare. He was a key figure in developing cancer therapeutics, including Herceptin, Avastin, and Rituxan.
Researchers found that long-term mutations are advantageous over short-term fitness gains, leading to the survival of less fit organisms. This unique study provides unprecedented detail on the complexity of evolution and challenges the traditional view of evolutionary success.
The American Association for Cancer Research (AACR) is honoring two renowned cancer researchers, Helen Blau and Nathanael Gray, for their groundbreaking contributions to the field. Helen Blau's work on regenerative medicine and cellular plasticity has led to new approaches in modeling diseases and regenerating damaged tissues.
Tiny single-celled algae and bacteria rebounded quickly after the Permian-Triassic mass extinction, consuming oxygen and slowing larger organisms' recovery. This process was driven by volcanic activity and resulting ocean acidification, which fueled explosive algae blooms.
Dr. Ching-Hon Pui, a world-renowned leukemia physician and researcher at St. Jude Children's Research Hospital, is the recipient of the 2011 AACR Joseph H. Burchenal Memorial Award for Outstanding Achievement in Clinical Research. He has made exceptional contributions to childhood cancer research and treatment.
Lianas, found in most tropical lowland forests, are outcompeting trees for sunlight, water, and nutrients. This intense competition is limiting tree growth and survival in these ecosystems.
Obese postmenopausal women are almost as likely to fracture as non-obese women, with specific sites like the upper arm, ankle, and lower leg being more prone to fractures in obese individuals. Poor mobility and a history of early menopause also play significant roles.
Researchers discovered that Antarctic icebergs raise chlorophyll levels, increasing carbon dioxide absorption in the Southern Ocean. The findings indicate a new dimension to previous research on icebergs' role in polar ecosystems and global carbon cycling.
Researchers found two ways neurons communicate: synchronized firing for simple messages and individual spikes for complex ones. This collective approach enhances transmission, but not for intricate information.
Researchers at the University of Pennsylvania have discovered a novel way to treat pancreatic cancer by activating the immune system to destroy the cancer's scaffolding. The strategy was tested in a small cohort of patients with advanced pancreatic cancer, resulting in substantial tumor shrinkage and reduced metabolic activity.
Researchers found that including falls history with clinical risk factors and bone mineral density values significantly enhances the accuracy of fracture prediction models. The study showed a 6% improvement in accuracy for men, with positive predictive values of 21.5% and 29.8% for women.
Researchers at LSU Health Sciences Center have identified a protein called c-MYC oncoprotein that enables cancer cells to resist DNA-damaging agents like cisplatin. The study suggests that inhibiting this protein may provide a novel strategy for cancer therapy in combination with DNA-damaging agents.
A new study projects that climate change will likely eliminate Joshua trees from 90 percent of their current range within 60 to 90 years. The species' ability to migrate via seed dispersal may be severely limited due to its reliance on seed-caching rodents.
A study of Yup'ik Eskimos found that high intake of omega-3 fats from fish reduces markers of chronic disease risk in overweight/obese people. Obesity did not increase inflammation and blood triglycerides among participants with high blood levels of omega-3 fats.
Dr. Helena Johansson and Dr. Maria-Belen Zanchetta receive $50,000 USD Fellowship to support their osteoporosis research at Sahlgrenska Academy and Instituto de Investigaciones Metabólicas, respectively. The award aims to promote research excellence in the bone field.
A Texas A&M University-led research team has discovered evidence of human occupation in Texas and North America dating back to 15,500 years ago. This finding challenges the traditional Clovis-first theory and suggests that early Americans arrived earlier than previously believed.
A national survey of US family medicine residency programs found that most limit pharmaceutical and industry interactions with residents, while some exclude all interactions. This shift aims to reduce the influence of industry on prescribing patterns and promote evidence-based prescribing.
Researchers found that most orthodontists prescribed removable retainers, with 58.2% opting for these over fixed lingual retainers. Patient compliance was generally high, with 60% wearing retainers more than 10 hours a day in the first three months.
Researchers challenge Inclusive Fitness Theory, citing flawed assumptions and misrepresentation of data. The debate highlights the importance of rigorous scholarship in scientific inquiry.
A study by Jackson Laboratory researchers reveals that mutations in the TDRD7 gene can cause juvenile cataracts and glaucoma, linked to a malfunctioning protein affecting eye lens development. The disorder disrupts stress granule production, leaving tissues susceptible to oxidative damage.