A Phase III trial of Radium-223 Chloride has shown improved survival rates among patients with bone metastases from advanced prostate cancer. The study found that patients taking radium-223 had a 30% lower rate of death compared to those receiving placebo.
University of Louisville bioengineering researchers will use a $3.33 million award from the Wallace H. Coulter Foundation to help commercialize promising academic innovations into medical solutions. The five-year program aims to save, extend and improve patients' lives with a focus on translational research.
Two Arizona university graduate students working at TGen have received $50,000 grants to study antibiotic resistance and Alzheimer's disease. The research will focus on understanding genetic mechanisms behind antibiotic resistance and developing models for neurodegenerative diseases.
Lawrence Livermore National Laboratory scientists used an ultrafast spectroscopic technique to measure breakouts in aluminum thin films at high strain rates. The research tested fundamental scaling laws and revealed unexpected insight into shock wave phenomena.
A new study by researchers from the UK found a link between living in river valley areas and an increased frequency of COPD symptom exacerbations. The unique climate in these areas, with high humidity and low dew point, retains particles and pollutants that can worsen lung symptoms.
Researchers have successfully developed a new, cheaper alloy for shape memory materials, which could revolutionize industries such as aerospace engineering and electronics. The new alloy, produced using copper, has shown promising properties and is expected to be cost-effective alternative to existing alloys like Nitinol.
Researchers at Johns Hopkins University have developed a protein switch that instructs cancer cells to produce their own anti-cancer medication. The goal is to deploy a new type of weapon that causes cancer cells to self-destruct while sparing healthy tissue.
A new combination therapy for kala azar has been developed, reducing treatment time from 30 days to 17 days and decreasing costs. However, without international funding, too few patients will benefit from this new treatment.
Research from the University of Edinburgh and Warwick University finds that powerful lobby groups in Europe are threatening public acceptance of genetically modified (GM) food. This has resulted in greater restriction of plant biotechnology research and development, hindering efforts to address global hunger and climate change.
A multi-institute team led by TGen will study triple-negative breast cancer, a highly aggressive form of the disease that disproportionately affects African-Americans. The research aims to uncover new ways of treating this aggressive form of breast cancer by understanding molecular makeup of breast cancer stem cells.
Researchers will explore how gene networks in the rice leaf respond to changing environmental conditions, particularly temperature and water availability. The study aims to develop crop varieties that can thrive under a range of circumstances, improving food security globally.
Research by Queensland University of Technology found that large dust particles can coagulate with ultrafine vehicle emissions particles, making the latter nearly invisible in their presence. This process reduces the risk of respiratory problems associated with ultrafine particle pollution.
Self-reported mental health disabilities among US non-elderly adults rose by 2.7% from 1997-99 to 2007-09, equating to nearly 2 million disabled adults. The increase was mainly among those with significant psychological distress and unmet mental health care needs.
Researchers at Northwestern University have discovered edible compounds that efficiently detect, capture and store carbon dioxide. The porous crystals, made from sugar, salt and alcohol, are simple to prepare and turn red when full of CO2.
Arizona State University researchers are studying the 10,000 Solutions participatory online platform to understand conditions for collective action. They aim to investigate how participation spreads, voting mechanisms impact community dynamics, and team formation affects solution quality.
Researchers will examine how humans have responded to changes in surrounding forests over multiple centuries, focusing on New Mexico's Jemez Mountains and the intersection of climate change, drought, and forest fires. The team aims to understand how humans can live sustainably within fire-adapted ecosystems.
Researchers have observed four cesium states with roughly the same size, surprising theorists and suggesting a new kind of ultracold chemistry at work. The three-body parameter varies consistently across different atomic species, implying universal behavior.
A recent study developed a system to continuously monitor blood glucose levels in diabetic dogs, revealing that none were receiving ideal treatment. The system provided valuable insights for improving treatment plans, including adjusting insulin doses and diets.
Two new risk indicators for prostate cancer have been identified, showing an association between benign prostatic hyperplasia and an increased risk of developing and dying from prostate cancer. Elevated prostate-specific antigen (PSA) levels in healthy men also predict long-term risk of developing prostate cancer.
Researchers are developing a computer-delivered intervention to increase parental motivation and adolescent engagement in diabetes care. The study, targeting urban African American youth, aims to address poor health outcomes related to diabetes management.
Researchers have found that a heart drug called levosimendan can improve the mechanical efficiency of the diaphragm, suggesting a new therapeutic approach to treat respiratory muscle weakness. The study showed that levosimendan prevents muscle fatigue in respiratory muscles and improves contraction force.
A study by an international consortium has identified five new genes associated with the risk of coronary artery disease (CAD). The research, published in PLOS Genetics, found that these genetic variants contribute to the development of CAD and heart attacks, particularly in South Asian populations.
African ranchers may need to rethink their approach to managing savanna rangelands, as a new study suggests that coexisting with wildlife can enhance cattle growth. Grazing by wild animals like zebras can actually improve the quality of grass for cattle during the wet season when grass becomes rank and unproductive.
Researchers found that singing complete texts was not decisive for patients with non-fluent aphasia. Rhythm and familiar song lyrics were more important for articulation. Daily expressions like 'How are you?' can be easier to articulate, regardless of whether sung or spoken.
A Johns Hopkins team discovered that MRI's strong magnet pushes on fluid in the inner ear's balance organ, leading to vertigo. This finding may affect results of functional MRI studies and could lead to a non-invasive method for diagnosing balance disorders.
Researchers found that Adeno-associated virus type 2 (AAV2) targets all different grades of breast cancer by activating death pathways. The virus causes 100% of cancer cell destruction within seven days, with majority of cell death proteins activated on the fifth day.
Researchers have sequenced the Aboriginal Australian genome, demonstrating that they descended directly from an early human expansion into Asia around 70,000 years ago. This study provides new insights into the dispersal of the first humans to leave Africa and re-writes the story of their journey to Australia.
A global sampling of 48 sites on five continents yields unprecedented data set, finding no clear relationship between productivity and plant species in small study plots. This challenges the 'hump-shaped' model developed by British ecologist J. Philip Grime, which has remained a textbook standard for nearly four decades.
Researchers found increased nitrate levels in coastal waters of Korea and Japan since the 1980s, correlated with human-generated atmospheric nitrogen. This shift may influence marine plants and ecosystems, favoring organisms adapted to high nitrate conditions.
Scientists at Dana-Farber Cancer Institute have found that a common cancer protein, cyclin E, plays a crucial role in memory formation and may be implicated in Alzheimer's disease. By inhibiting the activity of cyclin E, researchers believe they can improve memory function.
Archaeologists have uncovered a large Roman shipyard near Rome, which could be the largest of its kind in Italy. The massive building, dating back to the 2nd century AD, features eight parallel bays with wooden roofs and was likely used for shipbuilding activities.
A new study in Canada found that breast imaging reports generated with automatic speech recognition (ASR) systems have a higher error rate compared to conventional dictation transcription. At least one major error was found in 23% of ASR reports, while 4% of conventional reports contained errors affecting patient management.
Scientists have discovered a key to predicting emerging diseases like HIV, SARS, and flu by studying how viruses infect different species. By analyzing the relationships between species and viruses, researchers found that closely related flies are more susceptible to certain viruses.
A new study found that CT fluoroscopy for spine injections can reduce radiation exposure when the planning CT scan is optimized. The study suggests that reducing the coverage of the planning CT to only areas of interest and adjusting tube current or peak kilovoltage can lower the dose.
Researchers at the University of Alberta have developed a multi-cellular model of Zellweger's syndrome, a rare and deadly genetic disease, using fruit flies. The model mimics the human phenotype and is ideal for medical research due to its rapid development and low cost.
Digna Biotech receives FDA approval for cardiotrophin-1 as an acute liver failure treatment. The medicine is expected to work by acting as a messenger to damaged liver cells, helping them recover and restoring function. Cardiotrophin-1 has been shown to stimulate hepatic regeneration and protect hepatocytes during acute hepatic damage.
Berkeley lab researchers have discovered a complex protein structure in E.coli that plays a critical role in defending against viruses and other invaders. The 'Cascade' complex acts as a surveillance system, detecting and inactivating invading pathogens using RNA-guided target binding.
Researchers found that cardiac rehabilitation programs significantly improved patients' risk profiles after a transient ischemic attack (TIA) or mild stroke. Patients showed improvements in cholesterol levels, body mass index, waist circumference, and blood pressure.
A Department of Health and Human Services-funded study confirms earlier findings were likely due to laboratory error, ruling out XMRV's presence in patients with chronic fatigue syndrome or healthy donors. The study suggests there is no need to screen blood donors for the viruses at present.
The journal Optical Materials Express has published a special Focus Issue on Nanoplasmonics and Metamaterials, highlighting recent advances in nano-optics. Researchers have successfully developed new optical materials and nanofabrication techniques to control light fields beyond the diffraction limit.
According to research published in Group Processes and Intergroup Relations, people prefer friends who share their beliefs, values, and interests. With more choice, these similarities increase, but surprisingly, the quality of friendships doesn't necessarily improve.
A large and robust DNA matrix represents all mammalian families, covering their earliest history and deepest divergences. The dataset enables biologists to take the next leap in understanding mammalian evolution and biodiversity.
Researchers found genetic evidence that links fluid balance to a turning point in evolution, with the emergence of ENaC and Na-K-ATPase coinciding with multi-cellular organisms. The study suggests a link between these genes and the development of complex life forms.
Researchers found that GABA suppressed inflammatory immune responses involved in Type 2 diabetes development. The supplement also improved glucose tolerance and insulin sensitivity even after disease onset.
A team of scientists at the US Department of Agriculture has patented a method to convert commercial digital cameras into color infrared cameras for aerial photography. This technology allows for immediate image availability without further processing, making it ideal for detecting farmland extent and crop health. The innovation enable...
The study demonstrates that Aboriginal Australians descend directly from an early human expansion into Asia around 70,000 years ago. The results show that modern day Aboriginal Australians are the direct descendants of the first people who arrived in Australia as early as 50,000 years ago.
A study reveals how human activities can diminish the usefulness of ornamental traits like colorful feathers as signals of fitness. In contrast, a new field experiment shows that invasive yellow starthistle responds favorably to increased carbon dioxide levels. Plant breeding experts emphasize its potential to bring about a more positi...
A new study will assess the effectiveness of Project REACH, a prenatal intervention designed to prevent postpartum depression in adolescent mothers. The program focuses on strengthening social relationships and encouraging support, with a goal of reducing symptoms before they occur.
Researchers predict numerous human proteins required by HIV to replicate, discovering potential new targets for controlling the spread of HIV. The study also identifies prognostic markers to determine pathological outcome and AIDS development.
Researchers have created a large DNA matrix representing 99% of mammalian families, providing a robust framework for understanding evolutionary history and classification. The study reveals key diversification events in response to environmental changes, including the Cretaceous-Tertiary Mass extinction.
A study by UCLA scientists has found the first evidence of the H1N1 virus in animals in Africa, with 89% of pigs studied showing exposure to the virus. The discovery highlights the rapid spread of diseases globally and the importance of understanding viral transmission between humans, wild animals, and domestic animals.
Researchers used a new algorithm to predict human proteins that the HIV virus requires to replicate, offering potential new targets for controlling its spread. The study found many previously undiscovered proteins with high predictive value as prognostic markers.
Researchers sequenced the genome of a man who was an Aboriginal Australian, showing they are direct descendants of the first people to arrive on the continent 50,000 years ago. This challenges the prevailing theory of human migration, suggesting that Aboriginal Australians migrated to Australia earlier than previously thought.
The Global Climate and Energy Project (GCEP) is awarding $3.5 million to researchers at five universities to develop new technologies for advanced grid energy storage. The initiatives focus on high-efficiency electrochemical storage systems, solid oxide flow batteries, and low-cost flywheels.
In a study published in Science, researchers found that female promiscuity can increase genetic benefits in inbred populations. Females who mate with multiple males produce more viable offspring, while those who only mate with one male experience reduced reproductive success.
Residents who attend conferences focusing on missed cases exhibit lower error rates when interpreting x-ray images. The study found a significant reduction in discrepancies from 55 to 18 major errors after the conference became part of the resident education program.
Scientists at Oak Ridge National Laboratory have discovered a non-polar polymer material exhibiting up to 10 times the measured electro-active response as compared to strong piezoelectric materials. This finding has the potential to revolutionize the field of electro-active devices, including sensors, actuators, energy storage devices,...
A study by UK researchers found that over two-thirds of men seeking email advice experienced erection problems and a quarter were from the age group of 21-30 years. The study highlights the importance of online resources like the Sexual Advice Association in addressing sexual health concerns.
A recent DNA study suggests that humans settled in Asia in multiple waves of migration, contrary to previous genetic studies. The research found that Denisovans, an archaic human group, contributed DNA to modern populations in Southeast Asia and Oceania, including New Guineans, Australian aborigines, and Philippine populations.
Researchers at Stanford University have developed a nanoscale nonlinear optical device that can be controlled electronically, offering potential applications in data communications and information processing. The device uses plasmonics to intensify light and produce a powerful electrical field.