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Search results for “Phage”

429 results for "Phage"

Human antibodies against spores found by researchers suggest new tool to detect and treat anthrax

Scientists at Scripps Research Institute have identified human antibodies that can recognize spore surfaces, enabling the detection of anthrax and other bacterial spores. These antibodies could be used to passively immunize individuals exposed to anthrax, providing a simple and inexpensive treatment option.

SourceScripps Research Institute·JournalProceedings of the National Academy of Sciences·DateApr 15, 2002

NIAMS, NINDS fund multiple research grants in facioscapulohumeral dystrophy

Researchers are studying the molecular pathophysiology of FSHD using genome-wide approaches and developing animal models to understand the disease. The goal is to gain insight into the cellular and molecular processes leading to neuromuscular system dysfunction in FSHD patients.

SourceNIH/National Institute of Arthritis and Musculoskeletal and Skin Diseases·DateDec 13, 2001

Tips from the Journals of the American Society for Microbiology: July 2001

Researchers found that antacids significantly increased the survival rate of Vibrio vulnificus, a bacteria commonly contracted through eating raw oysters. Banning antibiotics in Denmark has also led to significant decreases in resistance rates among food animals.

SourceAmerican Society for Microbiology·JournalApplied and Environmental Microbiology·DateJul 11, 2001

New therapy uses viruses to attack bacteria

Researchers from the University of Florida College of Medicine have developed a new therapy using bacteriophages to treat Vibrio vulnificus infections. Most mice injected with both the bacterium and a deadly bacteriophage survived what would normally be a fatal infection, demonstrating the effectiveness of this approach.

SourceAmerican Society for Microbiology·DateMay 22, 2000
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A ringing endorsement for new tb drug target

Researchers have created a mutant strain of Mycobacterium tuberculosis that fails to establish a lethal chronic infection in mice. Targeting the pcaA gene, which codes for an enzyme essential for virulence, may lead to breakthroughs in TB treatment.

SourceHoward Hughes Medical Institute·JournalMolecular Cell·DateApr 20, 2000

Repetitive DNA in the genome of Neisseria meningitidis

The Neisseria meningitidis genome contains hundreds of repetitive elements that facilitate genome fluidity and antigenic variation. The most abundant element is the neisserial DNA uptake sequence, which enables transformation among different species.

SourceMax-Planck-Gesellschaft·JournalNature·DateMar 27, 2000

New drugs target HIV's deep pocket

Researchers have developed a new family of chemicals that bind specifically to the gp41 pocket, halting HIV's ability to infect cells. The compounds, created using mirror-image phage display, show promise as potential oral treatments for HIV, with advantages including reduced cell membrane penetration and lower likelihood of resistance.

SourceHoward Hughes Medical Institute·JournalCell·DateOct 1, 1999
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