1 Structures, Functions, and Adaptations of the Human LINE-1 ORF2 Protein
3 institutional releases
Published in Nature · View the paper (DOI)
A multidisciplinary study has elucidated the structure of the machinery responsible for writing much of our 'dark genome', a 98% unknown biological function. This discovery may lead to novel treatments for autoimmune diseases, cancer and neurodegeneration.
Coverage from 3 institutions
- New understanding of ancient genetic parasite may spur medical breakthroughs Rutgers University · Dec 14, 2023 · first to report
- Researchers reveal full structure of ‘ancient genetic parasite’ implicated in human diseases University of Alberta · Dec 14, 2023
- Research spotlight: Structural analysis and inhibition of human LINE-1 ORF2 protein reveals novel adaptations and functions Massachusetts General Hospital · Dec 19, 2023