Published in Nature · View the paper (DOI)
The study analyzed 3,000 cancer patients' genomes to identify common mutation patterns, revealing a significant role for structural alterations in gene expression. By integrating genome and transcriptome data, researchers gained insight into the complex interplay between DNA mutations and RNA alterations.
Coverage from 2 institutions
- A close-up look at mutated DNA in cancer cells Max Delbrück Center for Molecular Medicine in the Helmholtz Association · Feb 5, 2020 · first to report
- Characterizing RNA alterations in cancer European Molecular Biology Laboratory · Feb 5, 2020