Published in Nature Communications · View the paper (DOI)
A computational study has shown that cancer cells proliferate less and are more vulnerable to acidic conditions than initially thought. The researchers have identified potential therapeutic targets by analyzing how variations in pH affect metabolic enzyme activity, providing opportunities for new treatments.
Coverage from 2 institutions
- Acidic pH: The weakness of cancer cells Institute for Research in Biomedicine (IRB Barcelona) · Jul 31, 2018 · first to report
- Lowering pH inside cells may put the brakes on cancer growth H. Lee Moffitt Cancer Center & Research Institute · Aug 16, 2018