Anaphylactic shock: IgG antibodies and neutrophils play an unexpected role
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Published in Science Translational Medicine · View the paper (DOI)
A recent study has discovered that IgG antibodies can contribute to drug-induced anaphylactic shock by activating neutrophils, leading to high doses of vasodilating mediators. This finding explains up to 10-20% of previously unexplained cases and may help improve diagnosis and treatment for patients with this condition.