Published in Angewandte Chemie International Edition · View the paper (DOI)
Lugdunin, a cyclic peptide with strong antimicrobial properties, works by proton transport across bacterial membranes. The researchers discovered that the thiazolidine group in lugdunin forms a critical part of its structure and is essential for its antibacterial activity.
Coverage from 2 institutions
- Antibiotic ornament clasp Wiley · May 27, 2019 · first to report
- Antibiotic produced by the microbiome kills bacteria by disturbing energy metabolism German Center for Infection Research · Jun 4, 2019