Published in Immunity & Inflammation · View the paper (DOI)
The concept of Persistent Intracellular Extraintestinal Microbes (PIEM) expands human microbiome research to the body's internal tissues, influencing health and disease. PIEM, including latent viruses and bacteria, regulates host physiology over years and decades, affecting immune responses, vascular homeostasis, and chronic diseases.
Coverage from 2 institutions