Brain tumors in children: Hereditary genetic defect destabilizes protein regulation
3 institutional releases
Published in Nature · View the paper (DOI)
A genetic defect in 15% of children with medulloblastoma leads to disrupted protein production and metabolism, increasing the risk of cancer. The study identifies a new hereditary cause of medulloblastoma, which could lead to more effective treatment options for affected families.
Coverage from 3 institutions
- Brain tumors in children: Hereditary genetic defect destabilizes protein regulation German Cancer Research Center (Deutsches Krebsforschungszentrum, DKFZ) · Apr 1, 2020 · first to report
- Understanding brain tumors in children European Molecular Biology Laboratory · Apr 1, 2020
- Inherited mutation can predispose children to a type of brain tumor St. Jude Children's Research Hospital · Apr 1, 2020