Published in Science · View the paper (DOI)
Researchers have developed a fast CRISPR system that reduces cleavage time from hours to seconds, allowing for high-resolution DNA repair studies and single allele-level genetic editing. The technique uses light-sensitive nucleotides to control Cas9's action, enabling precise control over the editing process.
Coverage from 2 institutions
- Caging technique yields very fast CRISPR American Association for the Advancement of Science (AAAS) · Jun 11, 2020 · first to report
- Light-activated 'CRISPR' triggers precision gene editing and super-fast DNA repair Johns Hopkins Medicine · Jun 17, 2020