Published in Science Translational Medicine · View the paper (DOI)
Mutations in the PIK3CA cancer gene drive venous malformations, a common blood vessel abnormality causing painful and disfiguring lesions. Repurposing PI3K-inhibiting cancer drugs may offer a potential therapeutic avenue for patients with these vascular diseases.
Coverage from 2 institutions
- Cancer gene drives vascular disorder American Association for the Advancement of Science (AAAS) · Mar 30, 2016 · first to report
- Cancer drug could treat blood vessel deformities University College London · Mar 30, 2016