Published in Science · View the paper (DOI)
Researchers have created an mRNA-based approach to reprogram immune cells to attack specific targets, with promising results in treating heart failure. The technique, which is simpler and more temporary than current CAR T cell technology, holds potential for addressing a range of fibrotic diseases.
Coverage from 2 institutions
- Vaccine-like mRNA injection can be used to make CAR T cells in the body University of Pennsylvania School of Medicine · Jan 6, 2022 · first to report
- In vivo generation of engineered CAR T cells can repair a broken heart American Association for the Advancement of Science (AAAS) · Jan 6, 2022