Published in Journal of Clinical Investigation · View the paper (DOI)
A study by CRCHUM researchers reveals that chronic kidney disease can cause secondary diabetes through the buildup of urea in the blood. The disease impairs insulin secretion from pancreatic beta cells, leading to increased blood glucose levels and potentially progressing to diabetes.
Coverage from 2 institutions
- Chronic kidney disease may cause diabetes University of Montreal Hospital Research Centre (CRCHUM) · Aug 15, 2016 · first to report
- Urea impairs insulin-producing cells in chronic kidney disease JCI Journals · Aug 15, 2016