Comparative Efficacy and Safety of Wakefulness-Promoting Agents for Excessive Daytime Sleepiness in Patients With Obstructive Sleep Apnea
3 institutional releases
Published in Annals of Internal Medicine · View the paper (DOI)
Researchers found that solriamfetol, armodafinil–modafinil, and pitolisant reduce excessive daytime sleepiness in patients with obstructive sleep apnea already using conventional therapy. However, patients may be more likely to discontinue the use of these medications due to adverse events including headache, anxiety, and insomnia.
Coverage from 3 institutions
- Wakefulness-promoting agents effective for excessive daytime sleepiness but patients may discontinue due to side effects American College of Physicians · May 8, 2023 · first to report
- McMaster researchers find best treatment for excessive daytime sleepiness