Published in Science · View the paper (DOI)
Researchers discovered a protein complex that eliminates potentially harmful cells over time by measuring the duration of mitosis. The Mitotic Stopwatch Complex starts forming after prolonged mitosis and triggers cell arrest or death, providing new insights into cancer development.
Coverage from 2 institutions
- Memories of mitosis: Molecular mechanism that detects defects during cell division could aid cancer treatment Okinawa Institute of Science and Technology (OIST) Graduate University · Mar 28, 2024 · first to report
- Cell division quality control ‘stopwatch’ uncovered University of California - San Diego · Mar 28, 2024