Published in Cell Reports · View the paper (DOI)
A recent study published in Cell Reports reveals that DNA supercoiling is involved in regulating gene expression, rather than being just collateral damage. The researchers found that specific genes are massively activated in response to stimuli, and topoisomerase TOP2A plays a crucial role in this process.
Coverage from 2 institutions
- DNA structure itself is involved in genome regulation Centro Nacional de Investigaciones Oncológicas (CNIO) · Apr 13, 2021 · first to report
- The structure of DNA is found to be actively involved in genome regulation University of Seville · May 7, 2021