Published in Nature Communications · View the paper (DOI)
An international team of scientists identified sestrin-3 as a key regulator of gene networks in human epilepsy. Inhibiting sestrin-3 reduced seizures in animal models. The discovery offers promising starting points for new treatments, potentially avoiding drug resistance.
Coverage from 2 institutions
- Dragnet for epilepsy genes University of Bonn · Jan 23, 2015 · first to report
- New 'systems genetics' study identifies possible target for epilepsy treatment Imperial College London · Jan 23, 2015