Effective targeting of PDGFRA-altered high-grade 1 glioma with avapritinib
3 institutional releases
Published in Cancer Cell · View the paper (DOI)
Researchers found that avapritinib decreases aggressive gliomas in animal models and in an initial cohort of patients with high-grade glioma. The drug targets the PDGFRA gene, which is commonly mutated in this type of cancer.
Coverage from 3 institutions
- Re-purposed FDA-approved drug could help treat high-grade glioma Michigan Medicine - University of Michigan · Mar 13, 2025 · first to report
- Promising new therapeutic approach for pediatric brain tumors Medical University of Vienna · Mar 14, 2025
- Pediatric high-grade gliomas: Research reveals effective targeting with avapritinib Boston Children's Hospital · Mar 26, 2025