Genetic origin of neurodevelopmental disabilities in infants with heart disease
3 institutional releases
Published in Science · View the paper (DOI)
A new study has identified numerous genetic mutations associated with both congenital heart disease and neurodevelopmental disorders. The analysis revealed a high burden of damaging de novo mutations in genes highly expressed during heart development, suggesting a link between heart and brain development.
Coverage from 3 institutions
- Genetic origin of neurodevelopmental disabilities in infants with heart disease American Association for the Advancement of Science (AAAS) · Dec 3, 2015 · first to report
- In child heart patients, gene effects overlap in heart, brain development Children's Hospital of Philadelphia · Dec 8, 2015
- Genomic sequencing finds common link in congenital heart and brain disorders Columbia University Irving Medical Center · Dec 9, 2015