Published in Science · View the paper (DOI)
A new study in mice reveals that excess cholesterol may be hindering the repair of fatty protective sheaths around neurons. Researchers found that phagocytes, which ingest debris, had internal organs called lysosomes overwhelmed with cholesterol crystals, reducing their ability to repair myelin.
Coverage from 2 institutions
- How cholesterol contributes to age-related neuron impairment American Association for the Advancement of Science (AAAS) · Jan 4, 2018 · first to report
- Multiple sclerosis: Cholesterol crystals prevent regeneration in central nervous system Technical University of Munich (TUM) · Jan 4, 2018