Priming agents transiently reduce the clearance of cell-free DNA to improve liquid biopsies
3 institutional releases
Published in Science · View the paper (DOI)
Researchers developed intravenous priming agents that increase the recovery and detection of tumor-derived genetic fragments in liquid biopsies. In mouse models, these agents increased sensitivity for detecting small tumors from 10% to 75%. The approach may boost the sensitivity of liquid biopsies in cancer care and beyond.
Coverage from 3 institutions
- Improving sensitivity and success of liquid cancer biopsy in mice American Association for the Advancement of Science (AAAS) · Jan 18, 2024 · first to report
- Injectable agents could improve liquid biopsy for cancer detection and monitoring Broad Institute of MIT and Harvard · Jan 18, 2024
- Researchers improve blood tests’ ability to detect and monitor cancer Massachusetts Institute of Technology · Jan 18, 2024